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Catalogue of the papers and correspondence of SIR HANS ADOLF KREBS, FRS (1900-1981)


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Reference CSAC 113.4.86
Covering dates 1890-1984
Held by Sheffield University Library
Extent 257 boxes
Conditions of access NOT ALL THE MATERIAL IN THE COLLECTION IS YET AVAILABLE FOR CONSULTATION. ENQUIRIES SHOULD BE ADDRESSED IN THE FIRST INSTANCE TO:
THE LIBRARIAN,
SHEFFIELD UNIVERSITY LIBRARY,
SHEFFIELD S10 2TN.
Source of acquisition This very extensive collection has been brought together from several sources and at various dates between July 1982 and June 1986.
The main sources, made available by Lady Krebs, were Krebs's home at Iffley and his Metabolic Research Laboratory at the Radcliffe Infirmary, Oxford. A little material was received from Dr. J.R. Krebs. Microfilm transcripts and photocopies of his own research material on the history of biochemistry were kindly provided by Professor F.L. Holmes.
Creators Krebs, Sir, Hans Adolf, 1900-1981, Knight, scientist, biochemist and pharmocologist
Bibliography BIBLIOGRAPHY
The following Bibliography of 396 items is that which appears on microfiche to accompany the Royal Society Memoir (Biographical Memoirs of Fellows of the Royal Society, 30, 1984, 351 - 385). References in all sections of the catalogue are to this list, in the form (Bibliog....).
It should be noted that the Memoir itself refers only to a selection of 121 papers which are printed in a numbered list after the text. These numbers do not correspond to the Bibliography and have not been used in the compilation of the catalogue.
[1] 1923. Die Färbung des Skelettmuskels mit Anilinfarbstoffen. Arch. mikroskp. Anat. [Entw. Mech.] 97, 557.
[2] 1925. Zur Goldsolreaktion im Liquor cerebrospinalis. Klin. Wschr. 4. 1309.
[3] Die Flockung des kolloidalen Goldes durch Eiweisskörper. Biochem. Z. 159. 311.
[4] Die Theorie der Kolloidreaktionen im Liquor cerebrospinalis. Z. Immun. Forsch. exp. Ther. 44, 75.
[5] Zur Theorie der Weichbrodtschen Sublimatreaktion im Liquor cerebrospinalis. Dt. med. Wschr. 51, 1771.
[6] 1926. (With A. WITTGENSTEIN.) Studien zur Permeabilität der Meningen unter besonderer Berücksichtigung physikalisch-chemischer Gesichtspunkte. Z. ges. exp. Med. 49. 553.
[7] (With A. WITTGENSTEIN.) Untersuchungen über die Permeabilität der Meningen. Dt. med. Wschr. 52, 1161.
[8] (With A. WITTGENSTEIN.) Die Abwanderung intravenös eingeführter Substanzen aus dem Blutplasma. Ein Beitrag zum Permeabilitätsproblem und zur Theorie der Giftwirkung. I. und II. Mitteilung. Pflüger's Arch. ges. Physiol. 212, 268.
[9] (With A. WITTGENSTEIN.) Über die Abwanderung intravenös eingeführter Farbstoffe aus dem Blutplasma. Klin. Wschr. 5, 320.
[10] (With P. RONA.) Physikalisch-chemische Untersuchungen über die Isohämagglutination. I. Mitteilung: Die Bedeutung der Elektrolyte bei der Isohämagglutination. Biochem. Z. 169, 266.
[11] 1927. (With D. NACHMANSOHN.) Vitalfärbung und Adsorption. Biochem. Z. 186, 478.
[12] Über die Rolle der Schwermetalle bei der Autoxydation von Zuckerlösungen. Biochem. Z. 180, 377.
[13] Über den Stoffwechsel der Netzhaut. Biochem. Z. 189, 57.
[14] (With F. KUBOWITZ.) Über derr Stoffwechsel von Carcinomzellen in Carcinomserum und Normalserum. Biochem. Z. 189, 194.
[15] (With O. WARBURG.) Über locker gebundenes Kupfer und Eisen im Blutserum. Biochem. Z. 190, 143.
[16] Über den Stoffwechsel der Tumoren. Biologischen Zentralblatt 47, 59.
[17] 1928. Über das Kupfer im menschilchen Blutserum. Klin. Wschr. 7, 584.
[18] Über die Wirkung von Kohlenoxyd und Licht auf Häminkatalysen. Biochem. Z. 193, 347.
[19] Über die Chemische Konstitution des Atmungsferments. Klin. Wschr. 7, 1047.
[20] 1929. Über die Wirkung von Kohlenoxyd und Blausäure auf Hämatinkatalysen. Biochem. Z. 204, 322.
[21] Über die Wirkung der Schwermetalle auf die Autoxydation der Alkalisulfide und des Schwefelwasserstoffs. Biochem. Z. 204, 343.
[22] Stoffwechsel der Zellen und Gewebe. In: Methodik der wissenschaftlichen Biologie, Vol. 2, p. 1049.
[23] Über Hemmung einer Hämatinkatalyse durch Schwefelwasserstoff. Biochem. Z. 209, 32.
[24] (With J.F. DONEGAN.) Manometrische Messung der Peptidspaltung. Biochem. Z. 210, 7.
[25] 1930. Manometrische Messung des Kohlensäuregehaltes von Gasgemischen. Biochem. Z. 220, 250.
[26] Manometrische Messung der fermentativen Eiweisspaltung. Biochem. Z. 220, 283.
[27] Versuche über die proteolytische Wirkung des Papains. Biochem. Z. 220, 289.
[28] Über "Aktivierung" proteolytischer Fermente. Naturwissenschaften 18, 736.
[29] 1931. Über die proteolytische Wirkung von Papain und Kathepsin. Naturwissenschaften 19, 133.
[30] Über die Wirkung der Monojodessigsäure auf den Zellstoffwechsel. Biochem. Z. 234, 278.
[31] (With H. ROSENHAGEN.) Über den Stoffwechsel des Plexus chorioideus. Z. ges. Neurol. Psychiat. 134, 643.
[32] Manometrische Messung der Eiweisspaltung. In: Abderhalden's Handbuch der biologischen Arbeitsmethoden. Section IV. Part 1, p. 871.
[33] Über die Proteolyse der Tumoren. Biochem. Z. 238, 174.
[34] 1932. (With K. HENSELEIT.) Untersuchungen über die Harnstoffbildung im Tierkörper. Klin. Wschr. 11, 757.
[35] (With K. HENSELEIT.) Untersuchungen über die Harnstoffbildung im Tierkörper. II. Klin. Wschr. 11, 1137.
[36] (With K. HENSELEIT.) Untersuchungen über die Harnstoffbildung im Tierkörper. Hoppe-Seyler's Z. physiol. Chem. 210, 33.
[37] Untersuchungen über den intermediären Eiweisstoffwechsel.
Klin. Wschr. 11, 1692.
[38] Über den Stoffwechsel der Aminosäuren im Tierkörper. Klin. Wschr. 11, 1744.
[39] 1933. (H. WESTERKAMP.) Über Ketosäuren im Blutserum. Biochem. Z. 263, 239.
[40] (H. MANDERSCHEID.) Über die Harnstoffbildung bei den Wirbeltieren. Biochem. Z. 263, 245.
[41] Untersuchungen über den Stoffwechsel der Aminosäuren im Tierkörper. Hoppe-Seyler's Z. physiol. Chem. 217, 191.
[42] Weitere Untersuchungen über den Abbau der Aminosäuren im Tierkörper. Hoppe-Seyler's Z. physiol. Chem. 218, 157.
[43] (P. OSTERN.) Methode zur Bestimmung von Oxalessigsäure. Hoppe-Seyler's Z. physiol. Chem. 218, 160.
[44] (With H. EITEL and A. LOESER.) Hypophysenvorderlappen und Schilddrüse. Die Wirkung der thyreotropen Substanz des Hypophysenvorderlappens auf die Schilddrüse in vitro. Klin. Wschr. 12, 615.
[45] (With TH. BENZINGER.) Über die Harnsäuresynthese im Vogelorganismus. Klin. Wschr. 12, 1206.
[46] Grösse der Atmung und Gärung in lebenden Zellen. In: Oppenheimer's Handb. Biochem. 2. Auflage. Ergänzungswerk I. 863.
[47] Abbau der Fettsäuren. In: Oppenheimer's Handb. Biochem. 2. Auflage, Ergänzungswerk I, 936.
[48] Abbau der Aminosäuren. In: Oppenheimer's Handb. Biochem. 2. Auflage, Ergänzungswerk I, 939.
[49] Atmung und Gärung in lebenden Zellen. Tabul. Biol. III, 209.
[50] 1934. Über die Harnstoffbildung in der Leber. Hoppe-Seyler's Z. physiol. Chem. 230, 278.
[51] Urea formation in the animal body. Ergebn. Enzymforsch. III, 247.
[52] 1935. Metabolism of amino-acids. III. Deamination of amino-acids. Biochem. J. 29, 1620.
[53] Metabolism of amino-acids. IV. The synthesis of glutamine from glutamic acid and ammonia, and the enzymic hydrolysis of glutamine in animal tissues. Biochem J. 29, 1951.
[54] (With H. WEIL-MALHERBE.) Metabolism of amino-acids. V. The conversion of proline into glutamic acid in kidney. Biochem. J. 29, 2077.
[55] (With H. WELL.) Untersuchungen über die Urikolytischen Fermente (Uricase, Allantoinase, Allantoicase). In: Problèmes de Biologie et de Médecine, Éditions de l'État de la Littérature biologique et médicale, Moscou/Leningrad, p. 32.
[56] 1936. (With N.L. EDSON.) Micro-determination of uric acid. Biochem. J. 30, 732.
[57] (With N.L. EDSON and A. MODEL.) The synthesis of uric acid in the avian organism: hypoxanthine as an intermediary metabolite. Biochem. J. 30, 1380.
[58] Intermediate metabolism of carbohydrates. Nature Lond. 138, 288.
[59] Metabolism of amino acids and related substances. Ann. Rev. Biochem. 5, 247.
[60] 1937. (With W.A. JOHNSON.) Metabolism of ketonic acids in animal tissues. Biochem. J. 31, 645.
[61] Dismutation of pyruvic acid in Gonococcus and Staphylococcus. Biochem. J. 31, 661.
[62] (With W.A. JOHNSON.) The role of citric acid in intermediate metabolism in animal tissues. Enzymologia 4, 148.
[63] The intermediate metabolism of carbohydrates. Lancet 11, 736.
[64] (With W.A. JOHNSON.) Acetopyruvic acid ([alpha][gamma]-diketovaleric acid) as an intermediate metabolite in animal tissues. Biochem. J. 31, 772.
[65] The role of fumarate in the respiration of Bacterium coli' commune. Biochem. J. 31, 2095.
[66] Intermediary hydrogen-transport in biological oxidations. In: Perspectives in Biochemistry, Cambridge University Press, p. 150.
[67] 1938. Micro-determination of [alpha]-ketoglutaric acid. Biochem. J. 32, 108.
[68] (With E. SALVIN and W.A. JOHNSON.) The formation of citric and [alpha]-ketoglutaric acids in the mammalian body. Biochem. J. 32, 113.
[69] (With L.V. EGGLESTON.) The effect of insulin on oxidations in isolated muscle tissue. Biochem. J. 32, 913.
[70] Metabolism of amino acids and proteins. Ann. Rev. Biochem. 7, 189.
[71] 1939. (P.P. COHEN.) Microdetermination of glutamic acid. Biochem. J. 33, 551.
[72] (With Å. ÖRSTRÖM.) Microdetermination of hypoxanthine and xanthine. Biochem. J. 33, 984.
[73] (With Å. ÖRSTRÖM and M. ÖRSTRÖM.) The formation of hypoxanthine in pigeon liver. Biochem. J. 33, 990.
[74] (With Å. ÖRSTRÖM, M. ÖRSTRÖM and L.V. EGGLESTON.) The synthesis of glutamine in pigeon liver. Biochem. J. 33, 995.
[75] (W.A. JOHNSON.) Aconitase. Biochem. J. 33, 1046.
[76] (P.P. COHEN.) Transamination in pigeon breast muscle. Biochem. J. 33, 1478.
[77] The oxidation of d(+)proline by d-amino acid oxidase. Enzymologia 7, 53.
[78] (With L.V. EGGLESTON.) Bacterial urea formation. (Metabolism of Corynebacterium ureafaciens). Enzymologia 7, 310.
[79] With P.P. COHEN.) Metabolism of =293=-ketoglutaric acid in animal tissues. Biochem. J. 33, 1895.
[80] (With P.P. COHEN.) Glutamic acid as a hydrogen carrier in animal tissues. Nature, Lond. 144, 513.
[81] 1940. (With L.V. EGGLESTON.) The oxidation of pyruvate in pigeon breast muscle. Biochem. J. 34, 442.
[82] The citric acid cycle. Biochem. J. 34, 460.
[83] The citric acid cycle and the Szent-Györgyi cycle in pigeon breast muscle. Biochem. J. 34, 775.
[84] (E.A. EVANS, Jr.) The metabolism of pyruvate in pigeon liver. Biochem. J. 34, 829.
[85] (With D.H. SMYTH and E.A. EVANS, Jr.) Determination of fumarate and malate in animal tissues. Biochem. J. 34, 1041.
[86] (With L.V. EGGLESTON, A. KLEINZELLER and D.H. SMYTH.) The fate of oxaloacetate in animal tissues. Biochem. J. 34, 1234.
[87] (A. KLEINZELLER.) The effect of electrolytes on the respiration of pigeon breast muscle. Biochem. J. 34, 1241.
[88] (With L.V. EGGLESTON.) Biological synthesis of oxaloacetic acid from pyruvic acid and carbon dioxide. Biochem. J. 34, 1383.
[89] (D.H. SMYTH.) Vitamin B1 and the synthesis of oxaloacetate by Staphylococcus. Biochem. J. 34, 1598.
[90] 1941. Carbon dioxide assimilation in heterotrophic organisms. Nature, Lond. 147, 560.
[91] (A. KLEINZELLER.) The formation of succinic acid in yeast. Biochem. J. 35, 495.
[92] (With L.V. EGGLESTON.) Biological synthesis of oxaloacetic acid from pyruvic acid and carbon dioxide. 2. The mechanism of carbon dioxide fixation in propionic acid bacteria. Biochem. J. 35, 676.
[93] 1942. (With K. MELLANBY.) Digestibility of national wheatmeal. Lancet i, 319.
[94] (With D.M. STEPHENSON.) The utilisation of carbon dioxide by heterotrophic bacteria and animal tissues. Ann. Rep. Chem. Soc. 38, 257.
[95] The effect of inorganic salts on the ketone decomposition of oxaloacetic acid. Biochem. J. 36, 303.
[96] (With M.M. HAFEZ and L.V. EGGLESTON.) Indole formation in Bacterium coli commune. Biochem. J. 36, 306.
[97] Urea formation in mammalian liver. Biochem. J. 36, 758.
[98] 1943. The intermediary stages in the biological oxidation of carbohydrate. Adv. Enzymol. 3, 191.
[99] Urea synthesis in mammalian liver. Nature, Lond. 151, 23.
[100] Carbon dioxide assimilation in heterotrophic organisms. Ann. Rev. Biochem. 12, 529.
[101] (With L.V. EGGLESTON.) The effect of citrate on the rotation of the molybdate complexes of malate, citramalate and isocitrate. Biochem. J. 37, 334.
[102] (With K. MELLANBY.) The effect of national wheatmeal on the absorption of calcium. Biochem. J. 37, 466.
[103] (A. KLEINZELLER.) Oxidation of acetic acid in animal tissue. Biochem. J. 37, 674.
[104] 1944. (With L.V. EGGLESTON.) Metabolism of acetoacetic acid in animal tissues. Nature, Lond. 154, 209.
[105] (With L.V. EGGLESTON.) Micro-determination of isocitric and cis-aconitic acids in biological material. Biochem. J. 38, 426.
[106] 1945. (With the Vitamin A Sub-Committee.) Vitamin A deficiency and the requirements of human adults. Nature, Lond. 156, 11.
[107] (With L.V. EGGLESTON.) Metabolism of acetoacetate in animal tissues. 1. Biochem. J. 39, 408
[108] (With J.C. SPEAKMAN.) Dissociation constant, solubility, and the pH value of the solvent. J. Chem. Soc., p.593.
[109] 1946. (With J.C. SPEAKMAN.) The solubility of sulphonamides in relation to hydrogen-ion concentration. Brit. Med. J. 1. 47.
[110] (J. TOSIC.) Oxidations in Acetobacter. Biochem. J. 40, 209.
[111] The advent of biochemistry. Inaugural Lecture 8th May, the University of Sheffield.
[112] 1947. (With L.V. EGGLESTON and R. HEMS.) Urea synthesis in mammalian liver. Nature, Lond. 159, 808.
[113] Cyclic processes in living matter. Enzymologia 12, 88.
[114] (With W.O. SYKES and W.C. BARTLEY.) Acetylation and deacetylation of the p-amino group of sulphonamide drugs in animal tissues. Biochem. J. 41, 622.
[115] 1948. The D- and L-amino-acid oxidases. Biochem. Soc. Symp. I, 2.
[116] (With L.V. EGGLESTON.) Metabolism of acetoacetate in animal tissues. 2. Biochem. J. 42, 294.
[117] (With L.V. EGGLESTON.) Note on the manometric determination of succinic and [alpha]-ketoglutaric acids. Biochem. J. 43, 17.
[118] (With Vitamin C Sub-Committee.) Vitamin-C requirement of human adults. Experimental study of vitamin-C deprivation in man. Lancet 1, 853.
[119] (With L.V. EGGLESTON.) Observations on transimination in liver homogenates. Biochim. Biophys. Acta 2, 319.
[120] Quantitative determination of glutamine and glutamic acid. Biochem. J. 43, 51.
[121] (With L.V. EGGLESTON and R. HEMS.) Synthesis of glutamic acid in animal tissues. Biochem. J. 43, 406.
[122] Inhibition of carbonic anhydrase by sulphonamides. Biochem. J. 43, 525.
[123] (With F.J.W. ROUGHTON.) Carbonic anhydrase as a tool in studying the mechanism of reactions involving H2CO3, CO2 or HCO-3. Biochem. J. 43, 550.
[124] (J.R. STERN.) Carbon dioxide fixation in animal tissues. Biochem. J. 43, 616.
[125] (With W.A. JOHNSON.) Cell metabolism. Tabul. Biol. XIX, 100.
[126] (With J.B. BIALE.) Oxidative processes in minced flower buds of the cauliflower, Brassica oleracea. Amer. J. Bot. 35, 806.
[127] 1949. (With L.V. EGGLESTON and R. HEMS.) Distribution of glutamine and glutamic acid in animal tissues. Biochem. J. 44, 159.
[128] (With J.R. STERN, L.V. EGGLESTON and R. HEMS.)
Accumulation of glutamic acid in isolated brain tissue. Biochem. J. 44, 410.
[129] (With L.V. EGGLESTON.) Optical rotation of the molybdate complex of dextro-isocitric acid. Biochem. J. 45, 578.
[130] (With A.E. BENDER and N.H. HOROWITZ.) Amino-acid oxidase of Neurospora crassa. Biochem. J. 45, xxi.
[131] (With E.M. HUME.) Vitamin A requirement of human adults.
An experimental study of vitamin A deprivation in man.
Medical Research Council Special Report No. 264.
[132] 1950. (With A.E. BENDER.) The oxidation of various synthetic [alpha]-amino-acids by mammalian D-amino-acid oxidase, L-amino-acid oxidase of cobra venom and the L- and D-amino-acid oxidases of Neurospora crassa. Biochem. J. 46, 210.
[133] The tricarboxylic acid cycle. Harvey Lectures, Series XLIV, 165.
[134] Chemical composition of blood plasma and serum. Ann. Rev. Biochem. 19, 409.
[135] (With C. TERNER and L.V. EGGLESTON.) The role of glutamic acid in the transport of potassium in brain and retina. Biochem. J. 47, 139.
[136] Manometric determination of L-aspartic acid and L-asparagine. Biochem. J. 47, 605.
[137] Body size and tissue respiration. Biochim. Biophys. Acta 4, 249.
[138] 1951. Improved manometric fluid. Biochem. J. 48, 240.
[139] (L.E. HOKIN.) The synthesis and secretion of amylase by pigeon pancreas in vitro. Biochem. J. 48, 320.
[140] The use of 'CO2 buffers' in manometric measurements of cell metabolism. Biochem. J. 48, 349.
[141] (With L.V. EGGLESTON and C. TERNER.) In vitro measurements of the turnover rate of potassium in brain and retina. Biochem. J. 48, 530.
[142] The measurement of the turnover rate of steady state systems in living tissues. In: Radioisotope Techniques, Vol. 1, Medical and Physiological Applications (Proceedings of the Isotope Techniques Conference, Oxford, 1951) HMSO, London.
[143] Oxidation of amino acids. In: The Enzymes, Vol. II, Pt. 1, (Eds. J.B. Sumner and K. Myrbäck), p. 499, Academic Press Inc., New York.
[144] (L.E. HOKIN.) Amino-acid requirements of amylase synthesis by pigeon-pancreas slices. Biochem. J. 50, 216.
[145] (P.M. NOSSAL.) Estimation of L-malate and fumarate by malic decarboxylase of Lactobacillus arabinosus. Biochem. J. 50, 349.
[146] Carbon dioxide fixation in animal tissues. In: Symposia of the Society for Experimental Biology No. 5, Carbon dioxide Fixation and Photosynthesis, p. 1.
[147] The use of 'CO2-buffers' in manometric measurements of cell metabolism. In: Symposia of the Society for Experimental Biology No. 5, Carbon Dioxide Fixation and Photosynthesis, p.336.
[148] 1952. Urea synthesis. In: The Enzymes, Vol. II, Pt. 2, (Eds. J.B. Sumner and K. Myrbäck), p. 866, Academic Press Inc., New York.
[149] Neuere Entwicklungen auf dem Gebiete der Patho-Physiologie der Niere. Verhandlungen der Deutschen Gesellschaft für innere Medizin. Kongress für innere Medizin 58, 113.
[150] (With R.E. DAVIES.) Biochemical aspects of the transport of ions by nervous tissue. Biochem. Soc. Symp. 8, 77.
[151] (With H.L. KORNBERG.) Carbon dioxide exchanges between tissues and body fluids. Brit. Med. Bull. 8, 206.
[152] (P.M. NOSSAL.) The effects of glucose and potassium on the metabolism of pyruvate in Lactobacillus arabinosu: Biochem. J. 50, 591.
[153] (With S. GURIN and L.V. EGGLESTON.) The pathway of oxidation of acetate in baker's yeast. Biochem. J. 51, 614.
[154] (L.V. EGGLESTON and R. HEMS.) Separation of adenosine phosphates by paper chromatography and the equilibrium constant of the myokinase system. Biochem. J. 52, 156.
[155] (With D. HOLZACH.) The conversion of citrate into cisaconitate and isocitrate in the presence of aconitase. Biochem. J. 52, 527.
[156] 1953. (With R. HEMS.) Some reactions of adenosine and inosine phosphates in animal tissues. Biochem. Biophys. Acta 12, 172.
[157] Some aspects of the energy transformation in living matter. Brit. Med. Bull. 9, 97.
[158] The equilibrium constants of the fumarase and aconitase systems. Biochem. J. 54, 78.
[159] Equilibria in transamination systems. Biochem. J. 54, 82.
[160] (With K. BURTON.) The free-energy changes associated with the individual steps of the tricarboxylic acid cycle, glycolysis and alcoholic fermentation and with the hydrolysis of the pyrophosphate groups of adenosinetriphosphate. Biochem. J. 54, 94.
[161] (With A. RUFFO, M. JOHNSON, L.V. EGGLESTON and R. HEMS.) Oxidative phosphorylation. Biochem. J. 54, 107.
[162] (With M. JOHNSON, M.A.G. KAYE and R. HEMS.) Enzymic hydrolysis of adenosine phosphates by cobra venom. Biochem. J. 54, 625.
[163] (R. HEMS and W. BARTLEY.) Preparation of <;?;?;?;?; P-labelled adenosine triphosphate. Biochem. J. 55, 434.
[164] The Sheffield experiment on the vitamin C requirement of human adults. Proc. Nutr. Soc. 12, 237.
[165] 1954. (With W. BARTLEY and R.E. DAVIES.) Active transport in animal tissues and subcellular particles. Proc. Roy. Soc. B, 142, 187.
[166] Considerations concerning the pathways of syntheses in living matter. Synthesis of glycogen from non-carbohydrate precursors. Bull. Johns Hopkins Hosp. 95, 19.
[167] Some aspects of the metabolism of adenosine phosphates. Bull. Johns Hopkins Hosp. 95, 34.
[168] Excursion into the borderland of biochemistry and philosophy. Bull. Johns Hopkins Hosp. 95, 45.
[169] (R. WHITTAM and R.E. DAVIES.) Energy requirements for ion transport in steady-state systems. Nature, Lond. 173, 494.
[170] (L.V. EGGLESTON and D.H. WILLIAMSON.) The turnover rates of the phosphate groups of flavin-adenine dinucleotide and adenosine triphosphate during oxidative phosphorylation. Biochem. J. 56, 250.
[171] (W. BARTLEY.) The formation of phosphopyruvate by washed suspensions of sheep kidney particles. Biochem. J. 56, 387.
[172] Energy production in animal tissues and in microorganisms. In: Cellular Metabolism and Infections (Ed. E. Racker), p. 35, Academic Press Inc., New York.
[173] The citric acid cycle. Nobel Lecture, Les Prix Nobel en 1953, Stockholm.
[174] 1955. (With L.V. EGGLESTON and V.A. KNIVETT.) Arsenolysis and phosphorolysis of citrulline in mammalian liver. Biochem. J. 59, 185.
[175] (With L.V. EGGLESTON.) Arsenolysis and phosphorolysis of citrulline. In: Biochemistry of Nitrogen, p. 496, Academia Scientiarum Fennica, Helsinki.
[176] (With R. HEMS.) Phosphate-transfer reactions of adenosine and inosine nucleotides. Biochem. J. 61, 435.
[177] (With D.D. DAVIES.) Inhibition of the 'malic enzyme' by fluorocitrate. Arch. Sci. biol. 39, 533.
[178] The steering of metabolic processes. In: Lectures on the Scientific Basis of Medicine, Vol. V, 1955-56, p. 126.
[179] 1956. Die Steuerung der Stoffwechselvorgänge. Deut. Med. Wschr. 81, 4.
[180] (X.P. GEY.) The concentration of glucose in rat tissues. Biochem. J. 64, 145.
[181] The effects of extraneous agents on cell metabolism. In: Ciba Foundation Symposium on Ionizing Radiations and Cell Metabolism, p- 92
[182] 1957. Biochemical concepts in medicine. In: Oxford Medical School Gazette, 2, p. 1.
[183] (With H.L. KORNBERG.) A survey of the energy transformations in living matter. Ergebnisse Physiol. biol. Chem. exp. Pharmakol. 49, 212.
[184] (With H.L. KORNBERG.) Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle. Nature, Lond. 179, 988.
[185] (With R. WHITTAM and R. HEMS.) Potassium uptake by Alcaligenes faecalis. Biochem. J. 66, 53.
[186] Die energieliefernden Reaktionen des Stoffwechsels. Klin. Wschr. 35, 209.
[187] Control of metabolic processes. Endeavour 16, 125.
[188] 1958. Inhibitors of energy-supplying reactions. In: Symposia of the Society for General Microbiology, No. VIII, The Strategy of Chemotherapy, p. 104.
[189] (With P.K. JENSEN and L.V. EGGLESTON.) Phosphorolysis of citrulline by mammalian livers the effect of a bacterial activator. Biochem. J. 70, 397.
[190] 1959. The regulation of metabolic processes. Texas Rep. Biol. Med. 17, 16.
[191] Rate-limiting factors in cell respiration. In: Ciba Foundation Symposium on Cell Metabolism, p.1, J. & A. Churchill Ltd., London.
[192] (With L.V. EGGLESTON.) Permeability of Escherichia coli to ribose and ribose nucleotides. Biochem. J. 73, 264.
[193] 1960. Biochemical aspects of ketosis. Proc. Roy. Soc. Med. 53, 71.
[194] The cause of the specific dynamic action of foodstuffs. Drug Res. (Arzneim.-Forsch.) 10, 369.
[195] (With D. BELLAMY.) The interconversion of glutamic acid and aspartic acid in respiring tissues. Biochem. J. 75, 523.
[196] (With J.M. LOWENSTEIN.) The tricarboxylic acid cycle. In: Metabolic Pathways (Ed. D.M. Greenberg), Vol. 1, p. 129, Academic Press Inc., New York.
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[289] (With H.F. WOODS and L.V. EGGLESTON.) The cause of hepatic accumulation of fructose 1-phosphate on fructose loading. Biochem. J. 119, 501.
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[315] (With J.T. HUGHES and D. JERROME.) Ultrastructure of the avian retina. An anatomical study of the retina of the domestic pigeon (Columba liva) with particular reference to the distribution of mitochondria. Exp. Eye Res. 14, 189.
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[342] (With M. STUBBS.) Factors controlling the rate of alcohol disposal by the liver. In: Alcohol Intoxication and Withdrawal (Ed. M.M. Gross), p. 149. Plenum Publishing Corporation, New York.
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[364] Some general considerations concerning the use of carbohydrates in parenteral nutrition. In: Advances in Parenteral Nutrition (Ed. I.D.A. Johnston), p. 23. MTP Press.
[365] Regulatory mechanisms in purine biosynthesis. Adv. Enzyme Reg. 16, 409.
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[373] Zur Biologie der Jugendkriminalität. Wirtschaftspolitische Chronik 1, 27.
[374] On asking the right kind of question in biological research. In: Molecular Mechanisms of Biological Recognition (Ed. M. Balaban), p.27. Elsevier/North-Holland Biomedical Press, Amsterdam.
[375] Otto Warburg: Zellphysiologe, Biochemiker, Mediziner. Wissenschaftliche Verlagagesellschaft mbH, Stuttgart.
[376] (With P. LUND and M. EDWARDS.) Criteria of metabolic competence of isolated hepatocytes. In: Cell Populations: Methodological Surveys (B) Biochemistry (Ed. E. Reid), Vol. 9, p.1. Ellis Horwood Ltd., Chichester.
[377] 1980. (With H. TAEGTMEYER and R. HEMS.) Utilization of energy-providing substrates in the isolated working rat heart. Biochem. J. 186, 701.
[378] (With G. BAVEREL and P. LUND.) Effect of bicarbonate on glutamine metabolism. Int. J. Biochem. 12, 69.
[379] Zur Biologie der Jugendkriminalität. Sozialpädiatrie 2, 252.
[380] (With J.R. KREBS.) The "August Krogh Principle". Comp. Biochem. Physiol. 67B, 379.
[381] Glutamine metabolism in the animal body. In: Glutamine: Metabolism, Enzymology and Regulation (Ed. J. Mora and R. Palacios), p.319. Academic Press.
[382] Wie ich aus Deutschland vertrieben wurde.Dokumente mit Kommentaren. Medizinhistorisches Journal 15, 357.
[383] On the biology of juvenile delinquency: comments on the essay-by Felton Earls, "The social reconstruction of adolescence: toward an explanation for increasing rates of violence in youth". Perspect. Biol. Med. 23, 179.
[384] 1981. Otto Warburg (1883-1970). Oxford University Press. (English translation of [375]).
[385] (With J.E. BALDWIN.) The evolution of metabolic cycles. Nature. Lond. 291, 381.
[386] Evolutionary concepts in biological thought. In: Metabolism and Clinical Implications of Branched Chain Amino and Ketoacids (Ed. Walser and Williamson), p.3. Elsevier North Holland Inc. Amsterdam.
[387] The evolution of metabolic pathways. In: Molecular and Cellular Aspects of Microbial Evolution (Ed. Carlile, Collins and Moseley), p.215. Cambridge University Press.
[388] (With J.R. KREBS.) The "August Krogh Principle". Comp. Biochem. Physiol. 70B, 385.
[389] Response. Current Topics Cell. Reg. 18, 555.
[390] Biological and medical aspects of juvenile delinquency. In: New Horizons of Human Knowledge, p.79. UNESCO Press, Paris.
[391] Reminiscences and Reflections. Clarendon Press, Oxford.
[392] 1982. The discovery of the ornithine cycle of urea synthesis. Trends Biochem. Sci. 7, 76.
[393] (With D. WIGGINS and P. LUND.) Adaptation of urate synthesis in chicken liver. Comp. Biochem. Physiol. 72B, 565.
[394] (With K. DECKER.) Feodor Lynen 1911-1979. Biogr. Mem. Fellows Roy. Soc. 28, 261.
[395] 1983. (With J. VIÑA, G.T. SAEZ, D. WIGGINS, A.F.C. ROBERTS and R. HEMS.) The effect of cysteine oxidation on isolated hepatocytes. Biochem. J. 212, 39.
[396] (With D. WIGGINS, M. STUBBS, A. SOLS and F. BEDOYA.) Studies on the mechanism of the antifungal action of benzoate. Biochem. J. 214, 657.
SUPPLEMENTARY BIBLIOGRAPHY
Listed here are additional papers by Krebs, 1980-82. Titles and descriptions are taken from the list of publications from the Metabolic Research Laboratory, Oxford, 1980-83; the complete list is at A.26.
References to these papers in the catalogue are in the form (SUPP, Bibliog. no. ...).
20a. Gedenkworte für Feodor Lynen
In: Reden und Gedenkworte, pp. 39-42, Verlag Lambert Schneider, Heidelberg, 1980.
21. Gesellschaftskrankheiten - Jugenkriminalität vom biologisch-medizinischen Gesichtspunkt.
Der Kassenarzt 20, 44, 1980.
22. Jugendkriminalität vom biologisch-medizinischen Gesichtspunkt.
Deutsche Krankenpflegezeitschrift 10, 1980.
23. Biotechnology and values: how to arrive at sound value judgments.
International Cultural Foundation, 1980.
33. Biological aspects of juvenile delinquency.
In: Stress, 1, No.1, 7-9, 1980.
37. On asking the right kind of question in biological research.
In: Rheinisch-Westfälische Akademie der Wissenschaften 300, 7-30, 1981.
44. Introductory remarks.
Phil. Trans. R. Soc. Lond. B 293, 3-4, 1981.
56. Biotechnology and Values: How to arrive at sound value judgments. Social Science for Summer 1981.
57. Sessional Chairman's remarks.
Neurochem. Int. 2, 13, 1980.
58. Biological aspects of juvenile delinquency. (N.B. Duplicate of no.33.)
In: Stress 1, 7-9, 1980.
62. Zur Evolution des Citronensäurezyklus.
Naturw. Runds. 6, 225-228, 1982.
NOTE OF ADDITIONAL PUBLICATIONS
The collection contains considerable material which relates to publications unlisted in the Bibliography or Supplementary Bibliography, or which indicates an intention to publish. This material may range from a fully-prepared draft with references and figures ready for despatch to a journal to a reference in editorial correspondence. It applies especially, though not exclusively, to writings on social problems which were such a feature of Krebs's later years, but also includes such scientific contributions as his Jayne Lectures, as well as book reviews, abstracts, short notes and letters to the press omitted from the canon.
The relevant catalogue entry numbers are presented by Section.
A.437; A.440; A.453; A.903; A.909 - A.911; A.1081
B.34; B.95
C.28; C.228; C.267; C.329 - C.334
D.137; D.151; D.158; D.211; D.286; D.307; D.322; D.407; D.428; D.474; D.502 - D.505
E.11; E.15; E.72; E.131; E.136 - E.142; E.158; E.174; E.223; E 244 - E.247; E.248; E.249 - E 255; E.261; E.288 - E 290; E.291 - E.297; E.306; E.363 - E.365; E.366; E 374 - E.377; E.381; E.395; E.415; E.427 - E.433; E.444 - E.446
Note of additional publications
F.68; F.236; F.328 - F.330; F.336 - F.340
G.15; G.236
H.2; H.4; H.10; H.15; H.16; H.17; H.22; H.26; H.29; H.30; H.32; H.33; H.34; H.35; H.38; H.39; H.41; H.42; H.43; H.44; H.45; H.62; H.78; H.80; H.94; H.95; H.140; H 148; H.229 - H.242; H.279; H.291 - H.295; H.304; H.305; H.321; H.329; H.339 - H.341; H 344; H.359; H.361; H.364; H.381; H.388; H.393; H.394; H.397; H.398; H.400; H 402; H.404; H.412; H.415; H.419; H.420; H.421
J 29; J.35; J.145; J.297; J.354; J.507; J.535; J.789; J.840
Note Compiled by Jeannine Alton and Peter Harper
The work of the Contemporary Scientific Archives Centre, and the production of this catalogue, are made possible by the support of the following societies and institutions:
The Biochemical Society
The Charles Babbage Foundation for the History of Information Processing
The Institute of Physics
The Institution of Electrical Engineers
The Institution of Mechanical Engineers
The Nuffield Foundation
The Rhodes Trustees
The Royal Society of London
The Wolfson Foundation
The assembling and cataloguing of the collection have drawn on the time and goodwill of many. Particular thanks are due to:
Lady Krebs, for making the material available, for collecting family letters and documents from several sources, and for her many visits to provide information and encouragement over a long period;
Professor F. L. Holmes, for much invaluable information and advice, for his generosity in adding to the collection microfilm transcripts of his conversations with Krebs, microfilm copies of Krebs's laboratory notebooks, and the photocopy of a note-book of K. Henseleit, and for continuing visits and support;
Dr. D.H. Williamson and Mr. R. Hems for help in dealing with the research material, with special gratitude to Reg Hems for many visits of patient explanation and advice, for checking Section D and for making available a copy of his memorial address for Krebs;
Mr. C.K. Balmforth, Mr. M.S-M. Hannon and Mr. W.J. Hitchens of Sheffield University Library for mutual visits, help and encouragement;
Drs. Martin and Martina Jeningshausen-Lauster and Dr. C.J. Wells for help with manuscripts in German script;
Lady Phillips for invaluable assistance in the early stages of sorting and listing;
Miss M.J. Erskine for help with the index;
Mrs. M.M. Edwards, our long-term typist, for help with the conspectus and index and for more than usual patience with successive emendations and additions to the catalogue.

Administrative history:
Krebs, a pioneer of research in intermediary metabolism and an internationally-respected figure in biochemistry, died in 1981, the same year that his autobiography Reminiscences and Reflections was published. A further account of his life and work by two long-term colleagues, H.L. Kornberg and D.H. Williamson, appeared in 1984 (Biographical Memoirs of Fellows of the Royal Society, 30, 349-387). These recent and accessible sources, which have been drawn upon throughout the compilation of this catalogue, make it unnecessary to give more than a brief rehearsal of the facts of Krebs's career.
He was born in 1900 to a Jewish family in Hildesheim, where his father was a doctor. After studies at the universities of Göttingen, Freiburg and Munich he began a career as a medical graduate in Berlin with P. Rona, until the decisive step of his appointment as Research Assistant to Otto Warburg (1926-30) who strongly influenced him. Subsequently he worked briefly at Altona, then accepted an offer from S. Thannhause to join the Department of Medicine at Freiburg where he worked from April 1931 and where his first major work, the discovery of the ornithine cycle, was completed and met with immediate international recognition on its publication in 1932.
The following year saw the rise to power of the Nazi party, Krebs's suspension and dismissal from his post, and the start of a new career in England in the laboratory of Gowland Hopkins at Cambridge. In 1935 Krebs moved to Sheffield. Here his second major research discovery, of the citric or tricarboxylic acid cycle, was made; here also was created, from 1945, the Medical Research Council Unit for Research in Cell Metabolism which remained in being as the focus of his research and the base of his 'team' until his retirement in 1967. During the Sheffield period two of the greatest honours of the scientific world were awarded him - Fellowship of the Royal Society in 1947 and the Nobel Prize for Physiology and Medicine (jointly with F. Lipmann) in 1953. In private life it was also the period of his marriage and the birth of his three children.
In 1954 he accepted the Whitley Chair of Biochemistry at Oxford and moved there, with his Unit and many of his 'team', until 1967, the year of his official 'retirement'. In his autobiography Krebs uses inverted commas for the chapter on this subject, since he continued to work, still funded by the Medical Research Council and by other research grants and still with some at least of his original Sheffield 'team', in the Metablic Research Laboratory sited in the Radcliffe Infirmary, Oxford. His research continued to focus on physiological biochemistry and the regulation of biochemical processes, but he developed an increasing interest in the history and philosophy of science, its methodology and sociology, and in sociobiology and criminality. He was hard at work on all these topics, with a full programme planned ahead for publications and visits, when he died after a short illness.

Contents:
SECTION A BIOGRAPHICAL AND AUTOBIOGRAPHICAL A.1-A.1280
A.1 -A.7 Obituaries
A.8 -A.22 Articles and tributes
A.23 -A.26 Bibliographies
A.27 -A.40 Scrapbooks
With an introductory note
A.41 -A.399 Diaries and jotters
With an introductory note
A.400 -A.714 Career, honours and awards
With an introductory note
A.715 -A.887 Family correspondence and papers
With an introductory note
A.888 -A.924 Hildesheim (City and school)
A.925 -A.966 Miscellaneous biographical items
A.967 -A.1062 Personal correspondence
A.1063-A.1083 Shorter autobiographical writings
A.1084-A.1278 Reminiscences and Reflections
With an introductory note
A.1279, A.1280 Press-cuttings
SECTION B SHEFFIELD B.1-B.104
Introduction to Section B
B.1 -B.29 Pharmacology/Biochemistry Departments
B.30-B.40 Wartime research
With an introductory note
B.41-B.77 Funding and administration of Krebs's research
B.41-B.52 Rockefeller Foundation
With an introductory note
B.53-B.67 Medical Research Council Unit
With an introductory note
B.68-B.77 Miscellaneous
B.78-B.90 General University correspondence
B.91-B.104 Later contacts with Sheffield
With an introductory note
SECTION C OXFORD C.1-C.389
C.1 -C.96 Biochemistry Department
C.1 -C.34 General administration
C.35-C.58 Lectures
C.59-C.85 Building extension
C.86-C.96 Sub-departments
C.97 -C.182 Funding and administration of Krebs's research
C.97 -C.123 Medical Research Council Unit/Metabolic Research Laboratory
C.124-C.144 Financing bodies
C.145-C.182 Miscellaneous
C.183-C.240 Development of science of Oxford
With an introductory note
C.183-C.189 Development of Biology
C.190-C.201 'Oxford's needs in science'
With an introductory note
C.202-C.204 Biology centre
C.205-C.211 Zoology
C.212-C.236 Molecular Biophysics
C.237-C.240 Miscellaneous
C.241-C.334 University reform
With an introductory note
C.241-C.260 General correspondence and papers
C.261-C.273 Salaries
With an introductory note
C.274-C 278 Schedule A Professorships
C.279-C.328 Committees and Commissions of Inquiry
C.329-C.334 Publications
C.335-C.389 General University correspondence
C.335-C.361 Central administration
C.362-C.372 Electoral Boards
C.373-C.389 Libraries, departments, colleges and societies
SECTION D RESEARCH D.1-D.569
Introduction to Section D
D.1 -D.45 Laboratory notebooks
With an introductory note
D.46 -D.100 Indexed notes and memoranda
With an introductory note
D.101-D.514 Research projects
With an introductory note and a list of contents
D.515-D.548 Miscellaneous notes
D.549-D.569 Bibliographical references
SECTION E SCIENCE-RELATED INTERESTS E.1-E.507
Introduction to Section E
E.1 -E.204 History and philosophy of science
E.205-E.315 Sociology of research
With an introductory note
E.316-E.492 Sociobiology
With an introductory note
E.493-E.501 Science and religion
E.502-E.507 Background material
SECTION F VISITS AND CONFERENCES F.1-F.360
Introduction to Section F
SECTION G SOCIETIES AND ORGANISATIONS G.1-G.243
Introduction and list of contents
SECTION H PUBLICATIONS, LECTURES, BROADCASTS H.1-H.446
Introduction to Section H
H.1 -H.97 Publications
H.98 -H.271 Lectures
H.272-H.284 Broadcasts and television
H.285-H.446 Correspondence
SECTION J CORRESPONDENCE J.1-J.985
Introduction to Section J
SECTION K REFERENCES AND APPOINTMENTS K.1-K.72
SECTION L NON-PRINT MATERIAL L.1-L.108
List of contents
BIBLIOGRAPHY
With an introductory note
SUPPLEMENTARY BIBLIOGRAPHY
NOTE OF ADDITIONAL PUBLICATIONS
With an introductory note
The material fully documents all aspects of Krebs's career and is presented in the order shown in the List of Contents. Additional explanatory notes accompany many of the Sections, sub-sections and individual entries in the body of the catalogue. The following paragraphs aim only to draw attention to matters of particular substance or interest, since the material considerably expands the published accounts of Krebs's life and thought.
Krebs was of a naturally retentive disposition. He refers to this frequently in the drafts of his autobiography, one of which, written in 1975 under the rubric 'Collection of junk' and now included in A.1104, runs:
"Throughout my life I had a tendency not to throw things that I might care to see again or to use again away. This applied to all correspondence that contained personal and technical matters, all photographs, many drafts of papers, scientific notebooks of course, books, reprints, souvenirs of memorable occasions, newspaper cuttings, extracts of other readings, sayings, quotations (which I stuck into scrap books).
I kept no diaries except on special occasions, such as during the war years and during some of my travels."
Furthermore, the international acclaim which greeted the publication of the ornithine cycle work in 1932 had made him aware of the value of his research. Thus when he left Germany he was able to bring to England 'sixteen wooden boxes and several suitcases' of apparatus and also his notebooks and personal documents; and when he assembled the 'scrap books' referred to above, he added notes and comments linking the selected material to the events of his own life.
Section A (Biographical and autobiographical) is rich in material of this kind. It contains several 'scrap books', a very substantial number of engagement books, diaries and 'jotters' and full documentation of the long gestation of the eventual autobiography Reminiscences and Reflections. The events of Krebs's career, notably his successive moves to Warburg's laboratory, to Cambridge, Sheffield and Oxford are represented together with many other offers or applications for appointments. Of the many honours he received, pride of place goes to the Nobel Prize and his own careful recording of the event, and the concomitant ceremonies and correspondence. In addition to Krebs's own life, there is extensive correspondence and papers from the 1930s and later relating to his family and friends and reflecting on the suffering of the Jews in Germany, their enforced emigration to Britain, Palestine and America, renewal of contacts after the Second World War and claims of restitution from the German state.
Section B (Sheffield) is relatively short, but documents the funding of his research by the Rockefeller Foundation, the setting-up of his Medical Research Council Unit and the problems of establishing and running a biochemistry department. It includes Krebs's 'Reflections' on the history of the Sheffield department on the occasion of his resignation. The most important research discovery of the Sheffield period (the citric acid cycle) is recorded in his research notebooks in Section D, but Section B preserves correspondence and papers relating to the wartime research on nutrition and (very scantily) Krebs's ideas on carbon dioxide fixation.
Section C (Oxford) contains some not dissimilar material on the running (and in this case the major extension) of a university department and its sub-departments, Krebs's Medical Research Council Unit during and after his tenure of the Whitley Chair, and the funding of his research, including support from the Rockefeller Foundation. The Section is greatly extended and complicated, however, by Krebs's involvement in what he called 'debates on shortcomings'. These include his efforts to strengthen the development of science - and especially the biological sciences - in new or extended ways such as a 'Biology Centre', Zoology and Molecular Biophysics. Documents include not only Krebs's substantial unpublished account of the history of molecular biology at Oxford but photocopies of the relevant papers which the late J.W.S. Pringle (Linacre Professor of Zoology) made available to him. More general topics of 'University Reform' are salary and income structure, collegiate and non-collegiate appointments, the Robbins Committee, the National Incomes Commission and the Franks Commission; to all of these Krebs submitted memoranda for which drafts and background material survive. The records preserved here greatly expand Krebs's published writings on the subject at the time and later in his autobiography.
Section D (Research) is a very full record of the contributions to metabolic research made by Krebs and his collaborators over the long period 1926-81. It takes various forms - traditional laboratory notebooks, binders of dated and indexed notes, folders and boxes, and loose pages - and may include data and experimental results, records of discussions and information, reflections on work in hand or projected, drafts for publications, correspondence, extensive bibliographical references and background material usually annotated. The Section includes a photocopy of a laboratory notebook on the ornithine cycle research by Krebs's collaborator at Freiburg, K. Henseleit, and many pages of notes and results by long-term members of the Medical Research Council Unit, notably L.V. Eggleston, R. Hems and P. Lund.
Section E (Science-related interests) is one of the most interesting in the collection, since it gives substantial documentation of abiding interests of Krebs only briefly acknowledged in his own and other published accounts, and also contains much material for articles and lectures not listed in the extant bibliographies. The topics dealt with in the Section are history and philosophy of science (including considerable material on Otto Warburg), sociology of research (policy-making, funding, team-work and leadership, motivation and recognition), sociobiology and criminality, and the scientist's duty to bring his gifts to bear on social problems. Another note by Krebs of 1977 and now included in E.324 headed 'Why I concern myself with "Sociological" problems' may usefully be quoted here:
"People have asked me why I do not stick to my last (as Apelles, the Roman painter, shouted to the cobbler who criticised not only the shoes on his painting but also other matters) considering that I know little about sociology and that I had enough problems on my hands in connection with my research.
I am not only a scientist, but also a citizen, and as a citizen I have good reason to be worried about what I call the diseases of society. I hold the view that every citizen ought to contribute to the best of his ability to matters of public life, especially on the basis of his own professional experiences and skills. Having been trained as a physician and as a scientist I fancy, rightly or wrongly, that I can look upon problems of society from a special point of view, that of the medical scientist. It is also my view which I know is shared by others, that the great majority of those who profess sociological subjects are appallingly ignorant of the biology of Homo sapiens."
Section F (Visits and conferences) covers a long period (1933-81, with ongoing plans up to 1983) though in varying detail and with some overlap with material in other Sections. Krebs was in great demand as speaker, chairman or honoured guest, and he as an active scientist placed high value on the contacts and exchanges with colleagues offered by symposia, visits to institutions and laboratories and the like. Of special interest is the record 1962-77 of his visits to the annual international conferences on advances in enzyme regulation organised at Indianapolis, where he presented papers on his current research for publication in Advances in Enzyme Regulation.
Section G (Societies and organisations) includes some seventy British and overseas organisations. While some entries are relatively trivial, others are substantial sequences covering a lengthy timespan and matters of consequence such as research policy and grant applications. These include the Agricultural Research Council, the Biochemical Society, especially Krebs's chairmanship of the Society's Sub-committee on the Report of the Working Group on Molecular Biology, the Royal Society and the Science Research Council. There is also some material on organisations concerned with refugee scientists and with sociological matters.
Section H (Publications, lectures, broadcasts) brings together notes, drafts, correspondence and other related material for published and unpublished work 1927-81; it includes some book-reviews and some radio and television work. There is also an extensive sequence of correspondence with editors and publishers which testifies both to the many requests Krebs received to write or lecture which he was not able to accept and also to his long-term editorial commitments to two journals, Biochimica et Biophysica Acta and FEBS Letters.
Section J (Correspondence), though essentially confined to professional exchanges with colleagues and collaborators (personal correspondence being in Section A), is very extensive and diverse. It includes substantial exchanges with life-long friends such as H.K.F. Blaschko, D. Nachmansohn and F. Lipmann, and documents the careers of many younger scientists who spent some of their research years with Krebs and maintained contact with him as their careers developed. This material thus supplements and confirms the attention paid by Krebs in many of his writings to the concept of 'filiation' or 'scientific genealogy' in fostering scientific excellence, and his persuasion that his own Unit had been a step in such filiation.
The value placed on Krebs's judgment is shown by the very large number of requests for advice and references, which have been placed separately in Section K, subject to restricted access.
Section L, the last of the collection, is of non-print material and includes many photographs of Krebs, his family, colleagues and laboratories, sound-recordings and videotapes of lectures given by him. Of interest are the microfilms of transcripts of conversations between Krebs and the historian F.L. Holmes.
All references in the catalogue are to the Bibliography of 396 items which was published on microfiche to accompany the Royal Society Memoir, and to a Supplementary Bibliography of 11 items taken from the list of publications by members of the Metabolic Research Laboratory, Oxford, 1980-83. These bibliographies are listed, with permission, in the present catalogue.
This represents the latest information available on Krebs's published works. It supersedes the list of 356 items which Krebs published in his autobiography and the selection of only 121 items printed after the text of the Royal Society Memoir.
The manuscript collection contains considerable additional material relating to publications or to the intention to publish. This may range from a fully-prepared draft with references and figures ready for despatch to a journal to a reference in editorial correspondence. It applies especially, though not exclusively, to writings on social problems which were such a feature of Krebs's later years, but also includes such important scientific contributions as his Jayne Lectures, not to mention book-reviews and abstracts omitted from the canon. A separate list of catalogue entries for such material has been compiled and appears on pp. 671-72.
CONSPECTUS
This aims to relate Krebs's publications as defined above to their principal sources in the manuscripts. Only the more extended references, to research, publications and reception of the work, ensuing correspondence and the like, are given. Passing allusions in correspondence or requests for reprints are omitted.



SECTION B SHEFFIELD  CSAC 113.4.86/B.1 - B.104  [n.d.]

Administrative history:
In May 1935, at a meeting of the British Pharmacological Society at Cambridge, Krebs was offered the post of Lecturer in the Department of Pharmacology at the University of Sheffield by Professor E.J. (later Sir Edward) Wayne. Since there was not likely to be an equivalent post in Cambridge where he had settled immediately upon his arrival in England from Germany and since Sheffield offered him the possibility of continuing his research, he accepted the lecturership in Wayne's department. In 1938 the University agreed to change his title to Lecturer in Biochemistry and in 1945, the year in which the Medical Research Council established the Unit for Research in Cell Metabolism with Krebs as Honorary Director, Krebs was appointed to the University's newly-created Chair of Biochemistry. Everything still remained to be done in respect of the accommodation and staffing of the new department. Krebs's efforts to solve the space problem of the department met with considerable resistance within the university and it was not until 1952, when the university had at last provided greatly improved familities including the conversion of a disused cinema, that a three-year Honours course could be envisaged. The offer of a Professorship at Harvard (1951) greatly strengthened his bargaining position, enabling him to secure the facilities he sought. In 1954 he left Sheffield to take up the Whitley Professorship of Biochemistry at Oxford.
For correspondence re Krebs's appointment as Lecturer in Pharmacology at Sheffield see A.27, A.436, D.12, D.13.
For correspondence re Krebs's appointment to the Chair of Biochemistry at Sheffield including letters of congratulation see A.443. A reprint of his inaugural lecture is at A.28.
For photographic record of Krebs's later years at Sheffield see L.5.

Contents:
B.1 -B.29 PHARMACOLOGY/BIOCHEMISTRY DEPARTMENTS
B.30-B.40 WARTIME RESEARCH
With an introductory note
B.41 -B.77 FUNDING AND ADMINISTRATION OF KREBS'S RESEARCH
B.41-B.52 Rockefeller Foundation
With an introductory note
B.53-B.67 Medical Research Council Unit
With an introductory note
B.68-B.77 Miscellaneous
B.78-B.90 GENERAL UNIVERSITY CORRESPONDENCE
B.78-B.82 Central administration
B.83-B.86 Other university departments, committees and organisations
B.87-B.90 Sheffield hospitals
B.91-B.104 LATER CONTACTS WITH SHEFFIELD
With an introductory note

PHARMACOLOGY/BIOCHEMISTRY DEPARTMENTS  CSAC 113.4.86/B.1-B.29  [n.d.]

Pharmacology Department  CSAC 113.4.86/B.1  [n.d.]

Pharmacology Department  [no ref.]  1935-37

Contents:
Brief correspondence with E.J. Wayne.
Folder includes letter (1935) re arrangements for Krebs to fulfil teaching commitment at Cambridge after his appointment to the Sheffield post. (Rem. & Refl. p.94.)

Biochemistry Department  CSAC 113.4.86/B.2-B.29  1939-54

Contents:
A chronological sequence of correspondence and papers on the general affairs of the department.

Biochemistry Department  CSAC 113.4.86/B.2  1939

Contents:
Information on research workers in Krebs's department, provided in response to a request from the Vice-Chancellor, July.

Biochemistry Department  CSAC 113.4.86/B.3  1940

Contents:
Brief correspondence with Vice-Chancellor re Biochemical Society meeting at Sheffield.

Biochemistry Department  CSAC 113.4.86/B.4  1940

Contents:
Brief correspondence re transfer to Sheffield of personnel from P. Fildes's department of Bacterial Chemistry in London.

Biochemistry Department  CSAC 113.4.86/B.5  1940-41

Contents:
Correspondence and papers re departmental expenditure, equipment and personnel (L.V. Eggleston and R. Hems).

Biochemistry Department  CSAC 113.4.86/B.6  1944

Contents:
Exchange of letters with C.R. Harington re establishment of a research unit of Chemical Microbiology at Sheffield.
Krebs noted that since 1941 Sheffield had housed as an 'evacuee' the remnant of Fildes's department of Bacterial Chemistry: it was the wish of the university including Krebs himself that this type of research unit should continue at Sheffield after the war.

Biochemistry Department  CSAC 113.4.86/B.7  1944 (or later)

Contents:
5pp. typescript memorandum on accommodation for the Department of Biochemistry and 2 ms. diagrams of biochemistry accommodation, n.d.
This memorandum compares 1941 proposals for the accommodation of the Biochemistry department with the much less generous space allocation for Biochemistry in the 1944 plan.

Biochemistry Department  CSAC 113.4.86/B.8  1945

Contents:
Brief statement of the Biochemistry department's contribution to the war effort, produced in response to a university circular of 22 October.

Biochemistry Department  CSAC 113.4.86/B.9  1945-46

Contents:
Exchange of letters, March 1945, between R. Hems (on war service) and Krebs, on the occasion of Krebs's appointment as Professor of Biochemistry at Sheffield.
Note to the University bursar, July 1946, confirming that Hems had returned from war service.

Biochemistry Department  CSAC 113.4.86/B.10  1946

Contents:
Letter from T. Mann, 26 January, re possibility of placing a demobilised Polish Air Force officer as a student at Sheffield.

Biochemistry Department  CSAC 113.4.86/B.11  1947

Contents:
Correspondence with Vice-Chancellor on research interests of the Biochemistry Department and proposed new developments, January-February.
Folder includes 1p. Vice-Chancellor's Memorandum of a talk with Professors Smyth and Krebs, 15 January, and 1p. memorandum on development in the Department of Biochemistry sent by Krebs to the Vice-Chancellor, 30 January.

Biochemistry Department  CSAC 113.4.86/B.12  1947

Contents:
Correspondence with the Vice-Chancellor re appointments, award of Fellowship by (United States) National Research Council to J. Stern to study under Krebs, additional accommodation for the department, etc., June.
Krebs's letter of 10 June discusses the possible candidature of S.R. Elsden for the post of Senior Microbiologist in the University and Krebs's letter of 13 June refers to a letter of invitation to a chair of Biochemistry at London he had received.

Biochemistry Department  CSAC 113.4.86/B.13  1947

Contents:
Correspondence with Vice-Chancellor re accommodation and staffing of the department, November.

Biochemistry Department  CSAC 113.4.86/B.14  1948

Contents:
Correspondence with Vice-Chancellor and Bursar re departmental affairs, principally space problems.
Folder includes 3pp. typescript memorandum on accommodation for the Department of Biochemistry.

Biochemistry Department  CSAC 113.4.86/B.15  1948, 1951-53

Contents:
Applications for posts in Krebs's department.
Folder includes reply to an invitation from Krebs to apply for unspecified Chair at Sheffield.

Biochemistry Department  CSAC 113.4.86/B.16  1949

Contents:
Letters from Krebs's secretary in Sheffield during his absence in the United States as a Rockefeller Travelling Fellow, with news of the department, etc., March-April.
Correspondence re travel funds to aid proposed conference on CO2 fixation at Sheffield, May.

Biochemistry Department  CSAC 113.4.86/B.17  1950

Contents:
Correspondence with University Grants Committee re possibility of Rockefeller Foundation finance for building and equipment of a new biochemical laboratory at Sheffield, June-July.
Letters from Krebs's secretary providing news of the department while he was on holiday, August.

Biochemistry Department  CSAC 113.4.86/B.18  1951

Contents:
Correspondence with Vice-Chancellor re Rockefeller Foundation support for Krebs's research, departmental appointment, the Harvard Professorship, etc., April-July, November.
Folder also includes letter from Krebs to Dean of the Faculty of Medicine, J.G. McCrie, setting out the history of the Biochemistry Department.

Biochemistry Department  CSAC 113.4.86/B.19  1951

Contents:
Letter from L. Young re Biochemical Society meeting at Sheffield, July.
Letter from Krebs re history of Sheffield Biochemistry department in response to a circular from I.D. Ferguson who was writing a history of the Glasgow School of Physiology and Biochemistry, September.

Biochemistry Department  CSAC 113.4.86/B.20  1951-52

Contents:
'Undergraduate teaching in the department of Biochemistry'
Typescript and ms. drafts of note on organisation of courses.

Biochemistry Department  CSAC 113.4.86/B.21  1952

Contents:
Brief correspondence re proposed B.Sc. Honours Course in Biochemistry and new chemical laboratory dealing with the preparation of substances on a large scale, September-October.

Biochemistry Department  CSAC 113.4.86/B.22  1952

Contents:
'The teaching of Biochemistry and Microbiology in Sheffield University'
7pp. duplicated typescript paper prepared by Krebs and S.R. Elsden in support of an honours course in biochemistry, dated 11 October 1952.
Typescript and ms. draft of the above paper, with many ms. additions and corrections.

Biochemistry Department  CSAC 113.4.86/B.23  1952

Contents:
'The Growing Science of Biochemistry'
6pp. typescript, n.d.
Observations on the teaching of biochemistry at Oxford by W.O. James, extracted from a letter from James to A.R. Clapham.
2pp. typescript, n.d.
Manchester Guardian, 13 October 1952
Marginal emphasis has been added to an article on research grants and technological education.

Biochemistry Department  CSAC 113.4.86/B.24  1953

Contents:
1 letter only.

Biochemistry Department  CSAC 113.4.86/B.25  1954

Contents:
Formal letter of thanks from the University on the occasion of Krebs's resignation from the Sheffield Chair of Biochemistry.

Biochemistry Department  CSAC 113.4.86/B.26  1954

Contents:
'Reflections on Resigning from the Chair of Biochemistry at Sheffield'
3 drafts (one incomplete); brief correspondence with Vice-Chancellor.
The section headings include origin and resources, personnel, morale, choice of successor. Appendices detail the budget of the MRC unit, 1945-46 to 1954-55, full-time research workers in the Biochemistry Department supported by outside bodies, 1936-54, and the present personnel (1954) including university staff, MRC staff, special research fellows and research students.

Biochemistry Department  CSAC 113.4.86/B.27  1954

Contents:
Ms. and typescript drafts of portions of Krebs's 'Reflections', often very heavily corrected.

Biochemistry Department  CSAC 113.4.86/B.28  n.d

Contents:
Miscellaneous items re the supply of equipment and rationed foodstuffs to the department, various dates and n.d.
The folder also includes a Biochemistry Department Christmas card.

Biochemistry Department  CSAC 113.4.86/B.29  n.d

Contents:
18pp. typescript account of his own career and the work of the department, 1934-48, by L.V. Eggleston.
Continuation of the preceding to 1972, paginated 19-52.

WARTIME RESEARCH  CSAC 113.4.86/B.30-B.40  [n.d.]

Arrangement: The material is presented as a chronological sequence of correspondence and papers.



Related information: For additional material re wartime nutrition work see H.28, H.106, H.107, H.109, H.110, H.113, H.114, H.116, H.119, J 234, J.507, J.542, J.543, J.688.

Administrative history:
Krebs's particular contribution to the war effort lay in the field of nutrition research. He undertook investigations into the properties of 'National Wheatmeal', with K. Mellanby, the Sorby Research Fellow of the Royal Society, who was based in Sheffield from 1941. According to Krebs's own statement of his department's contribution to the war effort (B.8): 'the digestibility of National Wheatmeal and its effect on the absorption of calcium from the intestine were examined on human volunteers prior to the compulsory introduction of the National Wheatmeal, and of the addition of calcium salts to it. The results of the work contributed towards shaping government policy'. Krebs also undertook investigations into vitamin A and vitamin C requirements of human adults, work which was also carried out on volunteers. Nutrition surveys were carried out in the Sheffield area and Krebs served on the Yeast Sub-Committee of the Scientific Committee on Food Policy of the War Cabinet.
As a continuation of Krebs's work on the citric acid cycle he was interested, in the early war years, in 'the idea that carbon dioxide might be an active metabolite taking part in synthetic processes' and the possibility of carrying out experiments with isotopic carbon to determine the question of carbon dioxide participation.
(Rem. & Refl., pp.126-131).
There is little material in this section on these developments (see especially B.30) for further related correspondence which Krebs had set aside for the October 1973 Boston conference on the historical development of bioenergetics see E.31-E.33.
The diaries and research notebooks in Sections A and D also include additional information on research projects during the war years.

WARTIME RESEARCH  CSAC 113.4.86/B.30  1940,1942

Contents:
Correspondence, 1940, 1942, re Krebs's attempts to obtain carbon isotopes for research on tissue metabolism.

WARTIME RESEARCH  CSAC 113.4.86/B.31  1940

Contents:
Papers

WARTIME RESEARCH  CSAC 113.4.86/B.32  1941

Contents:
May-June 1941

WARTIME RESEARCH  CSAC 113.4.86/B.33  1941

Contents:
July-December 1941

WARTIME RESEARCH  CSAC 113.4.86/B.34  1942

Contents:
1942
Includes letter to the Lord President of the Council, C.R. Attlee, 3 March, re the 'almost complete failure' of the Scientific Committee on Food Policy (the Bragg Committee) and ms. draft of letter to The Times, 23 September, re the Nutrition Council advocated by its correspondents.

WARTIME RESEARCH  CSAC 113.4.86/B.35  1943

Contents:
Papers

WARTIME RESEARCH  CSAC 113.4.86/B.36  1944

Contents:
Papers

WARTIME RESEARCH  CSAC 113.4.86/B.37  1946-1947

Contents:
1946-47
Includes long letter of complaint from a vitamin experiment volunteer, principally about expenses.

Duplicated newsletters produced to enable the volunteers to keep in touch after the war.  CSAC 113.4.86/B.38-B.40  [n.d.]

Duplicated newsletters produced to enable the volunteers to keep in touch after the war.  CSAC 113.4.86/B.38  1946

Contents:
Sorby News Letter, no.3, February 1946. Described as the last Sorby News Letter.
Sorby Newsletter. New Series, no.1, April 1946.
Sorby Newsletter. New Series, no.2, July 1946.

Duplicated newsletters produced to enable the volunteers to keep in touch after the war.  CSAC 113.4.86/B.39  1947

Contents:
Sorby Newsletters, nos. 5, 6, 7, 1947

Duplicated newsletters produced to enable the volunteers to keep in touch after the war.  CSAC 113.4.86/B.40  1948-1949, 1977

Contents:
Sorby Newsletters, nos. 8, 9, 10, 1948
Sorby Newsletters, no.13, 1949
Folder also includes a short letter from Krebs to W. Bartley, 16 August 1977, re recorded message for a Sorby reunion.

FUNDING AND ADMINISTRATION OF KREBS'S RESEARCH  CSAC 113.4.86/B.41-B.77  [n.d.]

Rockefeller Foundation  CSAC 113.4.86/B.41-B.52  1935, 1937-42, 1946-47, 1949-55


Related information: For material re Rockefeller funding after Krebs's move to Oxford, see C.129-C.139. See also B.17, B.18, B.65, D.30.

Contents:
A chronological sequence of correspondence principally between Krebs and officers of the Foundation and relating to support for Krebs's research and the development of biochemistry at Sheffield. In a letter of 21 April 1947 (see B.45), Krebs noted the extent of his debt to the Rockefeller Foundation: 'At a critical period of my career, when I was young and without reputation, they generously supported me, first at Freiburg and especially during my first year in this country at Cambridge in 1933. Later the help of the Foundation contributed much to the development of my present department'.

Rockefeller Foundation  CSAC 113.4.86/B.41  1935

Contents:
1 letter only, predating Krebs's move to Sheffield.

Rockefeller Foundation  CSAC 113.4.86/B.42  1937-38

Contents:
1937 letter is the Rockefeller Foundation's response to a request from E.J. Wayne for financial assistance to purchase equipment for Krebs's research.
1938 material relates to Rockefeller Foundation proposal for a five-year scheme of assistance for Krebs's research conditional on the establishment of a Department of Biochemistry at Sheffield. Includes memorandum by Krebs on the probable requirements of the Department of Biochemistry during the next five years (3pp. typescript).

Rockefeller Foundation  CSAC 113.4.86/B.43  1939-40

Contents:
June 1939 correspondence relates to the award of a Rockefeller Fellowship to V.R. Potter to work in Krebs's laboratory.
September-October 1939 and July 1940 correspondence relates to working conditions in the department and the prospects for the continuation of research.

Rockefeller Foundation  CSAC 113.4.86/B.44  1941-42

Contents:
Correspondence re two one-year extensions of financial assistance to Krebs's department. In May 1941 Krebs submitted, in the form of a 4pp. letter, 'an account of the progress of the research which the Foundation has now supported for five consecutive years, and also a report on future plans and on the general working conditions in the present circumstances'.

Rockefeller Foundation  CSAC 113.4.86/B.45  1946-47

Contents:
1946 correspondence includes Krebs's letter to the Import Licensing Department re importing of scientific apparatus from the USA.
In April 1947 Krebs, in reply to congratulations on his election to the Royal Society, expressed his gratitude for Rockefeller Foundation's generous support for his work from Freiburg onwards.

Rockefeller Foundation  CSAC 113.4.86/B.46  1949-50

Contents:
1949 correspondence is with the British Commonwealth Scientific Office (North America) re Krebs's purchase of scientific equipment during a visit to the USA, with Rockefeller funds.
1950 correspondence relates to Krebs's enquiry whether the Foundation might be willing to consider an application for financial assistance in respect of new accommodation for the Sheffield Biochemistry Department.

Rockefeller Foundation  CSAC 113.4.86/B.47  1951

Contents:
Correspondence re Krebs's application to the Foundation for financial support for his research. Krebs's letter of 24 April and its appendices detail the research area and the equipment needs of the department. He was awarded a grant of $35,000 for a three-year period beginning 1 June.

Rockefeller Foundation  CSAC 113.4.86/B.48  1953

Contents:
1 letter only.

Rockefeller Foundation  CSAC 113.4.86/B.49  1954

Contents:
January
Correspondence re extension of Foundation support when current grant came to an end in June 1954. In his letter of 21 January Krebs submits an estimate of expenditure under the current grant for 1953-54 and lists of envisaged expenditure for 1954-55.

Rockefeller Foundation  CSAC 113.4.86/B.50  1954

Contents:
February-May
Continuing correspondence re support for Krebs's research.
In his letter of 6 February Krebs reflects on the prospect of the Oxford chair - 'the future of Oxford is so uncertain that I omit it entirely from my present plans for the future' - and in April the Foundation agreed to make available $80,000 for Krebs's research at Sheffield during the five-year period beginning 1 June 1954.

Rockefeller Foundation  CSAC 113.4.86/B.51  1954

Contents:
July-August
In his letter of 1 July Krebs confirmed that he would be going to Oxford on 1 October. Subsequent correspondence deals with problems in respect of the grant already made to Krebs for his work at Sheffield and the prospect of financial support for Krebs at Oxford.
Includes 1p. ms. note of totals of university grants 1946-54 and Rockefeller Foundation funding 1935-54.

Rockefeller Foundation  CSAC 113.4.86/B.52  1955

Contents:
Copies of letters from Rockefeller Foundation to Sheffield University re termination of Rockefeller grant to Sheffield for biochemical research under Krebs.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.53-B.67  1944-1954


Related information: See B.56, D.37.

Contents:
In 1944 the Medical Research Council made an offer to Sheffield University to establish a research unit in Krebs's department under his directorship. The MRC insisted on the provision of adequate accommodation and that Krebs's status should be raised to that of professor on the understanding that they would contribute half his professorial salary. Krebs suggested the designation of 'Unit for Research in Cell Metabolism'. This development was of great importance to the scope of Krebs's research, providing long-term financial support for the salaries of a team of collaborators, equipment and running expenses. In 1954, when Krebs accepted the Whitley Professorship of Biochemistry, the unit moved with him to Oxford. (Rem. & Refl., pp.132-3.)
At its inception the unit was a victim of a famous printing error. The new departmental notepaper was headed 'Medical Research Council. Unfit for Research in Cell Metabolism'.
A sequence of correspondence and papers presented chronologically.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.53  1944

Contents:
Letter from Vice-Chancellor, 22 November, informing Krebs that he had replied to Sir Edward Mellanby (Secretary of the Medical Research Council) 'to the effect that the University would greatly welcome the formation of an M.R.C. Unit of research in Biological Chemistry with you as Director if his Council decide to propose it'.
Copy of letter of same date from Vice-Chancellor to Dean of Medicine at Sheffield re new accommodation for Krebs.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.54  1945

Contents:
Correspondence, January, between Krebs and Sir Edward Mellanby.
In his letter of 17 January Krebs suggests as a name for the proposed unit: 'Unit for Research in Cell Metabolism'.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.55  1945

Contents:
Correspondence, October-December, between Krebs and Sir Edward Mellanby.
Relates to a proposal of the Therapeutic Research Corporation to pay the remuneration of additional members of Krebs's staff.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.56  1945

Contents:
Four examples of the letter-heading of the new departmental notepaper with the printing error 'Unfit for Research in Cell Metabolism', one incorporated into a draft page of Krebs's autobiography.

[no title or date]  CSAC 113.4.86/B.57-B.64

Contents:
Correspondence re salaries and staffing of MRC unit, 1946-50

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.57  1946

Contents:
February-March

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.58  1946

Contents:
April-November

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.59  1946

Contents:
December; 1947, January

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.60  1948-49

Contents:
Papers

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.61  1949

Contents:
June-July

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.62  1949

Contents:
June (relates to visit of H.P. Himsworth to Sheffield before taking over as MRC Secretary in October)

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.63  1950

Contents:
February-April

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.64  1950

Contents:
August-October

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.65  1951

Contents:
Correspondence re Rockefeller funding, research proposals, Harvard professorship and space problems at Sheffield, April-October.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.66  1954

Contents:
Letter of 13 July from the MRC detailing the total financial provision for Krebs's unit for each of the nine years 1945-46 to 1954-55.
Correspondence, October and December, re the resignation of F.P. Chappel from the staff of the unit.
Chappel, a member of the unit's staff for the three years to October 1954, had worked at the Department of Physics, University of Leeds.

Medical Research Council Unit, 1944-54  CSAC 113.4.86/B.67  1950-1955

Contents:
Various dates and n.d.
Medical Research Council Progress Report, 1950-53, of the Unit for Research in Cell Metabolism.
Two undated ms. lists of MRC personnel.
Also filed here for convenience is a notice of memorial service of Sir Edward Mellanby, 1955.

Miscellaneous  CSAC 113.4.86/B.68-B.77  [n.d.]

Contents:
B.68 Home Office licences
B.69, B.70 Suppliers of research material
B.71, B.77 Requests to visit/work in Krebs's laboratory.

[no title]  CSAC 113.4.86/B.68  1936-46

Contents:
Home Office Licences. Various dates

[no title or ref. or date]


Related information: For later material re Home Office licences see C.145-C.149.

Contents:
Notes for the guidance of Krebs in his application for a licence to carry out experiments on live animals and the letter transmitting the licence to Krebs (but not the licence itself), 1936; Letters reminding Krebs of the statutory requirement to submit a return of experiments and a blank form for the return, 1936-46.

[no title or date]  CSAC 113.4.86/B.69, B.70

Contents:
Correspondence with suppliers of scientific material for Krebs's research, presented in a chronological sequence.

Miscellaneous  CSAC 113.4.86/B.69  1945-49

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.70  1950-54

Contents:
Papers

[no title or date]  CSAC 113.4.86/B.71-B.77

Contents:
Correspondence re requests to visit or work in Krebs's laboratory, arranged in a chronological sequence. There is similar material in the correspondence files.

Miscellaneous  CSAC 113.4.86/B.71  1947-58

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.72  1950

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.73  1952(1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.74  1952(2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.75  1953(1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.76  1953(2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/B.77  1954

Contents:
Papers

GENERAL UNIVERSITY CORRESPONDENCE  CSAC 113.4.86/B.78-B.90  [n.d.]

Central administration  CSAC 113.4.86/B.78-B.82  [n.d.]

Contents:
A chronological sequence of correspondence and papers re the general affairs of the university.

Central administration  CSAC 113.4.86/B.78  1939-40

Contents:
Papers

Central administration  CSAC 113.4.86/B.79  1940


Related information: See also J.333.

Contents:
Correspondence with Vice-Chancellor, J.I.O. Masson, the General Secretary of the Society for the Protection of Science and Learning, Esther Simpson, and Eleanor Rathbone M.P. re the problems of enemy aliens at Sheffield University
According to Krebs the situation had arisen when the main buildings of the University were declared a 'special area' because of war research carried out there. As a result refugee students, if they were not interned, were barred from the University.
The position of alien refugees at other British universities, especially Cambridge, Bristol, Liverpool, Manchester, Birmingham and Durham-cum-Newcastle, is mentioned in the correspondence.

Central administration  CSAC 113.4.86/B.80  1943

Contents:
'A.R.P. Western Bank Rata No. 15, Spring Term 1943'
Addresses to the University Court, 29 November 1943, by the Senior Pro-Chancellor and the Vice-Chancellor.

Central administration  CSAC 113.4.86/B.81  1948-49

Contents:
Papers

Central administration  CSAC 113.4.86/B.82  1950-52

Contents:
Papers

Other university departments, committees and organisations  CSAC 113.4.86/B.83-B.86  [n.d.]

Other university departments, committees and organisations  CSAC 113.4.86/B.83  1942-1953


Related information: See H.113.

Contents:
Medical Sciences Club 1953
Notice of lecture by Krebs on 'Some Aspects of the Energy Transformations in Living Matter', 3 November (Bibliog. 157).
Medicine 1942, 1945
Includes programme of industrial medicine course with note of lecture by Krebs on nutritional requirements of industrial workers.

Other university departments, committees and organisations  CSAC 113.4.86/B.84  1949


Related information: See also J.178

Contents:
Microbiology.
3pp. typescript memorandum on the question of instituting a department of microbiology, with ms. draft of Krebs's covering letter to L.E.S. Eastham (Professor of Zoology).
4pp. typescript draft of the memorandum with Krebs's ms. additions and corrections.

Other university departments, committees and organisations  CSAC 113.4.86/B.85  1950

Contents:
Microbiology.
Correspondence with W.K. Slater of the Agricultural Research Council re possibility of setting up an ARC Unit in Microbiology at Sheffield under S.R. Elsden.

Microbiology.  CSAC 113.4.86/B.86  1935-1949

Contents:
Committee of the Non-Professional Staff 1939
North Wing 1949
Publication of Sheffield University Medical Society
Sheffield Jewish Students Association 1935
Women Day Students organisation 1937

Sheffield hospitals  CSAC 113.4.86/B.87-B.90  [n.d.]

Sheffield hospitals  CSAC 113.4.86/B.87  1944

Contents:
Krebs's appointment to supervise the biochemical departments of the Royal Sheffield Infirmary and Hospital, February.
2pp. typescript notes on the 'Biochemical Laboratory, Sheffield Royal Infirmary', with ms. corrections and additions. Initialled by Krebs and dated 27 November 1944.
2pp. typescript note on the 'Biochemical Laboratory', 21 December 1944.

Sheffield hospitals  CSAC 113.4.86/B.88  1945

Contents:
5pp. typescript memorandum on 'Developments at the Biochemical Laboratories of the Sheffield Royal Infirmary and Hospital'.
Letter from Krebs to Professor Barnes, 12 February, enclosing the preceding.

Sheffield hospitals  CSAC 113.4.86/B.89  1945-47

Contents:
Brief correspondence re transferring of testing of patients from Krebs's department to hospital biochemical departments, appointment of Senior Biochemist at the Royal Sheffield Infirmary and Hospital, etc.
In November 1945 Krebs accepted an invitation to the office of Honorary Biochemist at the Royal Sheffield Infirmary and Hospital and in May 1947 he accepted the same office at the Children's Hospital, Sheffield.

Sheffield hospitals  CSAC 113.4.86/B.90  1951-52, 1954

Contents:
Correspondence and papers re requests for Krebs's advice on the treatment of patients, from Sheffield hospitals and the Postgraduate Medical School of London.

LATER CONTACTS WITH SHEFFIELD  CSAC 113.4.86/B.91-B.103  1954-58, 1961-64, 1973-80

Administrative history:
Various dates Krebs retained a close interest in the university after his departure for Oxford. He returned on a number of occasions to lecture, most notably for the July 1980 Biochemical Society meeting held in his honour, and was consulted on appointments and university development especially in the biochemical and medical fields.

Sheffield University Student Biochemical Society, 1958, 1964, 1973-80.  CSAC 113.4.86/B.91, B.92  [n.d.]

Two folders

Administrative history:
In 1958 Krebs gave the inaugural lecture of the society on 'Rate control of metabolic processes'. In 1974 he returned to give the Biochemical Society Lecture on 'The role of chemical equilibrium systems in organ function'. For many years. Krebs served as Vice-President of the Society.

Sheffield University Student Biochemical Society, 1958, 1964, 1973-80.  CSAC 113.4.86/B.91  1958, 1964

Contents:
Papers

Sheffield University Student Biochemical Society, 1958, 1964, 1973-80.  CSAC 113.4.86/B.92  1973-80

Contents:
Papers

LATER CONTACTS WITH SHEFFIELD  CSAC 113.4.86/B.93  1961

Contents:
Sheffield University Philosophical Society, 1961
Invitation to lecture (declined).

LATER CONTACTS WITH SHEFFIELD  CSAC 113.4.86/B.94  1963

Contents:
Correspondence with the University Bursar re accommodation at Crewe Hall for a meeting of the Society of General Microbiology, 1963.
As a result of Krebs's intervention the 27 year-old mattresses at Crewe Hall were replaced.

LATER CONTACTS WITH SHEFFIELD  CSAC 113.4.86/B.95  1975-1977

Contents:
Sheffield University Medical Society, 1975-77
Krebs was invited to contribute to a programme of lectures to celebrate the fortieth year of publication of the Society's magazine Northwing. He had contributed to the magazine's summer edition of 1943.

LATER CONTACTS WITH SHEFFIELD  CSAC 113.4.86/B.96  1978

Contents:
Brief correspondence re Biochemistry Department's collection of Krebs's reprints; drafts of Krebs's introduction to his collected papers at Sheffield. 1978.

LATER CONTACTS WITH SHEFFIELD  CSAC 113.4.86/B.97  1979-1980

Contents:
Brief correspondence re Sheffield University Centenary Appeal, 1979-80.
Krebs was a patron of the appeal.

Biochemical Society meeting at Sheffield, July 1980, to honour Krebs's 80th birthday. See also G.26.  CSAC 113.4.86/B.98-B.100  [n.d.]

Biochemical Society meeting at Sheffield, July 1980, to honour Krebs's 80th birthday.  CSAC 113.4.86/B.98  1978-80

Contents:
Correspondence with organisers re arrangements

Biochemical Society meeting at Sheffield, July 1980, to honour Krebs's 80th birthday.  CSAC 113.4.86/B.99  [n.d.]

Contents:
Notes and draft for Krebs's speech.
4pp. draft of 'Envoi' chapter of autobiography presumably used in preparation of speech.

Biochemical Society meeting at Sheffield, July 1980, to honour Krebs's 80th birthday.  CSAC 113.4.86/B.100  1980

Contents:
Biochemical Society Bulletin, February 1980, with announcement of July meeting at Sheffield.
Biochemical Society Bulletin, June 1980, with programme of Sheffield meeting.
Leaflet with details of arrangements for Sheffield meeting.

Biochemical Society Bulletin, February 1980, with announcement of July meeting at Sheffield.  CSAC 113.4.86/B.101  n.d

Contents:
Sheffield University Dining Club
2pp. typescript and 1p. ms. draft of speech of reminiscences on the early history of the club, given by Krebs on a visit to Sheffield.
2pp. typescript reminiscences, possibly delivered on the some occasion.

References and appointments  CSAC 113.4.86/B.102-B.104  [n.d.]

References and appointments  CSAC 113.4.86/B.102  1954-56, 1958

Contents:
Papers

References and appointments  CSAC 113.4.86/B.103  1973, 1977

Contents:
Papers

References and appointments  [no ref. or date]

References and appointments  CSAC 113.4.86/B.104  [n.d.]

Contents:
Miscellaneous

SECTION C OXFORD  CSAC 113.4.86/C.1 - C.389  [n.d.]


Related information: For correspondence and papers re Krebs's election to the Whitley Professorship of Biochemistry, see A.555-A.566.

Contents:
C.1-C.96 BIOCHEMISTRY DEPARTMENT
C.1-C.34 General administration
C.35-C.58 Lectures
C.59-C.85 Building extension
C.86-C.96 Sub-departments
C.97-C.182 FUNDING AND ADMINISTRATION OF KREBS'S RESEARCH
C.97-C.123 Medical Research Council Unit/Metabolic Research Laboratory
C.124-C.144 Financing bodies
C.145-C.182 Miscellaneous
C.183-C.240 DEVELOPMENT OF SCIENCE AT OXFORD
With an introductory note
C.183-C.189 Development of Biology
C.190-C.201 'Oxford's needs in science'
With an introductory note
C.202-C.204 Biology Centre
C.205-C.211 Zoology
C.212-C.236 Molecular Biophysics
C.237-C.240 Miscellaneous
C.241-C.334 UNIVERSITY REFORM
With an introductory note
C.241-C.260 General correspondence and papers
C.261-C.273 Salaries
With an introductory note
C.274-C.278 Schedule A Professorships
C.279-C.328 Committees and Commissions of Inquiry
C.329-C.334 Publications
C.335-C.389 GENERAL UNIVERSITY CORRESPONDENCE
C.335-C.361 Central administration
C.362-C.372 Electoral Boards
C.373-C.389 Libraries, departments, colleges and societies

BIOCHEMISTRY DEPARTMENT  CSAC 113.4.86/C.1-C.96  [n.d.]


Related information: See also C.335-C.361

General Administration  CSAC 113.4.86/C.1-C.34  [n.d.]

Contents:
A chronological sequence of correspondence and papers re the general affairs of the department.

General Administration  CSAC 113.4.86/C.1  1954

Contents:
'Notes on informal speech to assembled members of Oxford Biochem. Dept. on assuming office, 2.10.1954'.

General Administration  CSAC 113.4.86/C.2  1954-1955

Contents:
Various lists of departmental personnel, 1954-55.

General Administration  CSAC 113.4.86/C.3  1955

Contents:
Correspondence re arrangements for visiting lecturer, 1955.

General Administration  CSAC 113.4.86/C.4  1955-1958

Contents:
Applications for/enquiries about posts in Krebs's department, 1955, 1957-58.

General Administration  CSAC 113.4.86/C.5  1955-1956

Contents:
'Departmental Estimates 1955/56'
4pp. typescript with details of expenditure and income.

General Administration  CSAC 113.4.86/C.6  1956

Contents:
Brief correspondence re departmental personnel, 1956.
Minute of staff meeting, 13 November 1956, re appointment.

General Administration  CSAC 113.4.86/C.7  1953-1956

Contents:
Papers re teaching survey of members of department, 1956.
Folder also includes 'Undergraduate Teaching Before HAK - Practical Classes 1953-1954' and material on the duties of demonstrators, 1955-56.

General Administration  CSAC 113.4.86/C.8  1957

Contents:
Material re effect of insufficiency of the quinquennial grant on the department, 1957.

General Administration  CSAC 113.4.86/C.9  1957-1958

Contents:
Correspondence and papers re joint research project with Nuffield Department of Surgery, 1957-58.

General Administration  CSAC 113.4.86/C.10  1958-1958

Contents:
Brief correspondence re departmental staff meetings, January and November 1958.
'Outline proposal for the revision of the Honour School of Biochemistry with reference to the inclusion of suitable courses in Physiology', 1 May 1958. By C.W. Carter.
Brief correspondence with Registry re undergraduate and research student numbers, June-July 1958.

General Administration  CSAC 113.4.86/C.11  1956-1959, nd

Contents:
Krebs's minute of student comments on departmental teaching, 28 January 1959.
Statement of grave concern about the state of teaching in the department (2pp. typescript). Not by Krebs. n.d. but not later than October 1959.
Proposal for reorganisation of Biochemistry teaching. n.d. ? 1959.
Folder also includes earlier (1956) minute re Biochemistry teaching.

General Administration  CSAC 113.4.86/C.12  1959

Contents:
Duplicated typescript notes (8pp.) 'intended to introduce students to the Department of Biochemistry at Oxford University'. By Krebs. September 1959.

General Administration  CSAC 113.4.86/C.13  1961-1963

Contents:
Lists of departmental personnel, 1961 and 1963.
Minutes of discussions re new Fellowship at Wadham College in chemistry-cum-biochemistry, 1961 and 1962.

General Administration  CSAC 113.4.86/C.14  1961-1963

Contents:
Correspondence re arrangements for visiting lecturers, 1961-63.

[no title or date]  CSAC 113.4.86/C.15, C.16

Contents:
'Future of Final Year Students'. Various dates 1961-67.
Principally Krebs's typescript notes of interviews with under-graduate and postgraduate students, reports of tutors and supervisors, references provided by Krebs, etc.

General Administration  CSAC 113.4.86/C.15  1961-65

Contents:
Papers

General Administration  CSAC 113.4.86/C.16  1966-67

Contents:
Papers

General Administration  CSAC 113.4.86/C.17  1961-67

Contents:
Krebs's orders for U.S. Government publications

General Administration  CSAC 113.4.86/C.18  1963-64

Contents:
Correspondence and papers re secretarial appointments

[no title]  CSAC 113.4.86/C.19, C.20  1964-68

Contents:
Correspondence, etc., with The Wellcome Trust re fellowships, research training scholarships, etc.

General Administration  CSAC 113.4.86/C.19  1964

Contents:
Papers

General Administration  CSAC 113.4.86/C.20  1965, 1967-68

Contents:
1965 material includes brief exchange re 90th birthday of Sir Henry Dale.

General Administration  CSAC 113.4.86/C.21  1965

Contents:
'Survey of Graduates in Biochemistry - January 1965'
'Quinquennial Estimates - Department of Biochemistry' (1965).

General Administration  CSAC 113.4.86/C.22, C.23  1965

2 folders

Contents:
Correspondence and papers re arrangements for visiting lecturers, 1965.

General Administration  CSAC 113.4.86/C.24  1966

Contents:
Papers re appointment of Krebs's successor as Whitley Professor of Biochemistry, 1966.
Includes Krebs's 'Memorandum for Hebdomadal Council and Electors of the Whitley Professorship', 10 September 2 copies and letter from A.L.P. Norrington commenting on the memorandum, 23 September.

General Administration  CSAC 113.4.86/C.25  1966

Contents:
Duplicated typescript notes (8pp.) 'intended to introduce students to the Department of Biochemistry at Oxford University'. By Krebs. October 1966.

General Administration  CSAC 113.4.86/C.26  1966

Contents:
'Whitley Professorship'
2pp. typescript draft with ms. corrections, 31 October 1966. Principally relates to departmental budget.
'Departmental Finance'
1p. typescript (carbon), 14 December 1966.

General Administration  CSAC 113.4.86/C.27  1966-67

Contents:
Papers re use of classrooms in the department, practical classes, visiting lecturers, departmental seminars, applicant for lecturership in department, etc.

General Administration  CSAC 113.4.86/C.28  1967

Contents:
Material re departmental expenditure financed from outside grants
Includes draft letters to the editor of the Oxford Magazine and the Registry.

General Administration  CSAC 113.4.86/C.29  1967

Contents:
Papers re transfer to Oxford of Krebs's successor and his research team
Includes Krebs's 'Report on Recent Events in the Department of Biochemistry', 17 February, which relates to structural alterations necessitated by the transfer (Rem. & Refl., pp.204-5), and a draft of the section in Krebs's last annual report on the transfer of responsibility to his successor.

General Administration  CSAC 113.4.86/C.30  1967

Contents:
Lists of departmental and microbiology unit personnel

General Administration  CSAC 113.4.86/C.31  1971; 1973; 1979

Contents:
Project work for Biochemistry department students in Krebs's laboratory
Biochemistry department examinations
Honorary MA degree for chief technician in Biochemistry

General Administration  CSAC 113.4.86/C.32  1927; 1973

Contents:
History of Biochemistry department.
Letter from Edward Whitley (1973) re his father, the founder of the Whitley Professorship, with abridged pedigree of Whitley family.
Folder also includes copy of booklet printed to commemorate the opening of the Oxford School of Biochemistry, 1927.

General Administration  CSAC 113.4.86/C.33  [n.d.]

Contents:
Miscellaneous items re departmental personnel, research, student numbers, teaching, examinations, etc.

General Administration  CSAC 113.4.86/C.34  1957-65

Contents:
Krebs's annual departmental reports

Lectures  CSAC 113.4.86/C.35-C.58  [n.d.]

[no title or date]  CSAC 113.4.86/C.35-C.37

Contents:
'First Year Biochemists'
Contents of a ring-back binder so inscribed.
The material is divided into three folders for ease of reference.

Lectures  CSAC 113.4.86/C.35  n.d

Contents:
'The nature of biochemistry'
7pp. typescript draft, with a very few ms. additions and corrections, paginated 4-10.
'The nature of biochemistry'
2pp. typescript draft, headed 'HLK' and 'JRQ' [Kornberg and Quayle].
'The nature and scope of biochemistry'
2pp. typescript draft, with ms. corrections.
Untitled 6pp. typescript draft on the nature of biochemistry, headed with the names W.H. Elliot and K.M. Jones.

Lectures  CSAC 113.4.86/C.36  1960,nd

Contents:
'Detailed Notes'
4pp. typescript draft, with ms. additions and corrections, on the nature of biochemistry. By R.B. Fisher.
'How to become a Biochemist'
2pp. typescript draft, with ms. corrections.
'What happens to the food we eat'
3pp. typescript draft, dated 8 August 1960.
Miscellaneous ms. and typescript notes on the nature of biochemistry.

Lectures  CSAC 113.4.86/C.37  1946

Contents:
Krebs's 1946 inaugural lecture at Sheffield, 'The advent of biochemistry', with underscoring and marginal emphasis.
'Prospects for the development of biochemistry in the light of the resolutions of the XXI Congress of the Communist Party of the Soviet Union', with underscoring and marginal emphasis.
Miscellaneous background material.

Lectures  CSAC 113.4.86/C.38  1900, 1960 1961

Contents:
'Two introductory lectures for first-year biochemists'
6pp. typescript draft of first lecture, with ms. corrections, 1960.
7pp. typescript draft of second lecture, with ms. corrections, 1960.
1p. typescript note and 1p. ms. note on the history of biology since 1900, 1961. Found with the preceding.

[no title or date]  CSAC 113.4.86/C.39-C.43

Contents:
'Lectures, Final Year Biochemists'
Contents of a folder so inscribed.
The material has been divided into 5 folders for ease of reference.

Lectures  CSAC 113.4.86/C.39  1960

Contents:
'Synopsis of Final Honour Biochemistry School Lectures, Hilary Term, 1960'
Notice of a series of lectures by Krebs on 'Special aspects of the energy-giving reactions (cause of specific dynamic action of foodstuffs, rate control of energy metabolism)'. Hilary Term, 1960.
2pp. typescript draft introduction to the series.
2pp. typescript draft, 20 January 1960. Untitled but 'mainly quoted from Medawar'.
Miscellaneous ms. and typescript notes.

Lectures  CSAC 113.4.86/C.40  1960

Contents:
'F.H. Biochem. Class Work January 1960'
Krebs's ms. and typescript notes of experimental method.
Experimental account and results in other hands, probably students.

Lectures  CSAC 113.4.86/C.41  1960-1961

Contents:
Duplicated notes for practical classes. Hilary Term, 1960.
1p. typescript note on the use of the departmental library by 4th-year honours students, 14 October 1961.

Lectures  CSAC 113.4.86/C.42  1962

Contents:
Notice of a series of lectures by Krebs, on 'Control of Metabolic Processes', Hilary Term, 1962.
Duplicated notes for practical classes: advanced enzymology and cell fractionation studies, 1962.

Lectures  CSAC 113.4.86/C.43  1964

Contents:
Duplicated notes for practical classes, with ms. tables of results, 1964.

[no title or date]  CSAC 113.4.86/C.44-C.47

Contents:
'F.H.S. Physiology Lectures I'
Contents of a spring-back binder so inscribed.
The material is divided into four folders for ease of reference.

Lectures  CSAC 113.4.86/C.44  1959

Contents:
'Energy transformations in living matter'
Krebs's first lecture, given 17 October 1959.
5pp. typescript draft, with a few ms. additions and corrections.
'Untitled second lecture, given 24 October 1959.
6pp. typescript draft.
Krebs discusses the question of how much energy is released by respiration on the one hand and fermentation on the other.

Lectures  CSAC 113.4.86/C.45  1959

Contents:
'Intermediary stages of the energy yielding reactions'
Krebs's third lecture, given 31 October 1959.
5pp. typescript draft.
Untitled fourth lecture, given 7 November 1959.
6pp. typescript draft.

Lectures  CSAC 113.4.86/C.46  1959

Contents:
Untitled fifth lecture, given 14 November 1959.
6pp. typescript draft and 1p. ms. note.
Untitled sixth lecture, given 21 November 1959.
4pp. typescript draft.

Lectures  CSAC 113.4.86/C.47  n.d

Contents:
'General observations on the energy giving reactions'
22pp. typescript draft, with ms. additions. Includes tables and list of references.
Miscellaneous ms. and typescript notes.

[no title or date]  CSAC 113.4.86/C.48-C.52

Contents:
'F.H.S. Physiology Lectures II'
Contents of a spring-back binder so inscribed.
The material has been divided into five folders for ease of reference.

Lectures  CSAC 113.4.86/C.48  1956-1962 nd

Contents:
List of seven lectures to Final Honours Physiology, n.d
Dated ms. and typescript notes for Final Honours Physiology lectures, 1956-62.

Lectures  CSAC 113.4.86/C.49  1959-1960

Contents:
Untitled seventh lecture, dated 28 November 1959.
7pp. typescript draft, with ms. additions and corrections.
Untitled first lecture, dated 23 January 1960.
8pp. typescript draft, with ms. additions and corrections.

Lectures  CSAC 113.4.86/C.50  1960

Contents:
Untitled second lecture, dated 30 January 1960.
8pp. typescript draft, with ms. additions and corrections.
Untitled third lecture, dated 6 February 1960.
7pp. typescript draft, with ms. additions and corrections.

Lectures  CSAC 113.4.86/C.51  n.d

Contents:
Undated ms. and typescript notes.

Lectures  CSAC 113.4.86/C.52  n.d

Contents:
Printed background material.

Lectures  CSAC 113.4.86/C.53  1946, 1966

Contents:
Biology option for chemists, 1966.
3pp. duplicated typescript course outline.
7pp. draft of Krebs's introductory lecture, typescript and printed material (extract from Krebs's 1946 inaugural lecture at Sheffield).

Lectures  CSAC 113.4.86/C.54  1973-1974

Contents:
Letter from course organiser and list of lectures on disorders of human metabolism, 1973-74.
Ms. notes and printed background material.

Lectures  CSAC 113.4.86/C.55, C.56  1972-1973

Two folders.

Contents:
'Regulation of the redox state'
Drafts of three lectures, 1972-73, letter from course organiser, reading list and lecture timetable.

Lectures  CSAC 113.4.86/C.57  1973, nd

Contents:
Lecture timetable for F.H.S. Biochemistry option on the regulation of metabolic pathways, n.d.
Krebs gave two lectures on compartmentation.
Ms. and typescript notes on compartmentation, 1973.

Lectures  CSAC 113.4.86/C.58  1973

Contents:
Unattributed ms. and typescript notes. Some material dated in 1973.

Building extension, 1955-64  CSAC 113.4.86/C.59-C.85  [n.d.]

Administrative history:
During Krebs's tenure of the Whitley Professorship a major building extension was planned and completed - an eight-storey wing which more than doubled the size of the department. Although the University Grants Committee provided the greater part of the finance for the extension and its equipment, Krebs was obliged to approach the Wellcome Trust for the finance for an extra research floor for the Head of Department (Rem. & Refl., p.196).

[no title]  CSAC 113.4.86/C.59-C.74  1955-60

Contents:
Correspondence and papers re building extension with Registry, University Surveyor, the architects and academic colleagues, 1955-60.

Building extension, 1955-64  CSAC 113.4.86/C.59  April-May 1955

Contents:
Folder includes Biochemistry location plan, May.

Building extension, 1955-64  CSAC 113.4.86/C.60  June-July 1955

Contents:
Includes memorandum giving draft requirements for the first extension of the department.

Building extension, 1955-64  CSAC 113.4.86/C.61  August-September 1955

Contents:
Papers

Building extension, 1955-64  CSAC 113.4.86/C.62  October-December 1955

Contents:
Papers

Building extension, 1955-64  CSAC 113.4.86/C.63  May-June 1956

Contents:
Includes 8pp. memorandum on the Biochemistry extension submitted to the Building and Development Committee of Council and the General Board.

Building extension, 1955-64  CSAC 113.4.86/C.64  July 1956 (1)

Contents:
Includes memorandum (various drafts) of additional information on the Biochemistry extension for the Building and Development Committee of Council and the General Board. Deals with curriculum changes and general aspects of the development of Biochemistry.

Building extension, 1955-64  CSAC 113.4.86/C.65  July 1956 (2)

Contents:
Includes memoranda on 'Biochemistry Extension - Plan B', 'Future of Biochemistry', 'Physical Biochemistry' and 'Virus research'.
The memorandum on Plan B has the ms. comments of senior members of the department.

Building extension, 1955-64  CSAC 113.4.86/C.66  August-October 1956

Contents:
Includes memoranda on the requirements for the extension and the canteen problem, sent to the architects.

Building extension, 1955-64  CSAC 113.4.86/C.67  November-December 1956

Contents:
Includes undated papers found with 1956 material.

Building extension, 1955-64  CSAC 113.4.86/C.68  January-June 1957

Contents:
Includes notes on meeting of members of the Biochemistry department, the University Surveyor and the architects, 27 February, and schedule of accommodation for the extension.

Building extension, 1955-64  CSAC 113.4.86/C.69  July-August 1957

Contents:
Includes committee papers for consideration of the Building and Development Committee, 29 July, with timetable prepared by the University Surveyor of the planning stages for the Biochemistry extension.

Building extension, 1955-64  CSAC 113.4.86/C.70  October-December 1957

Contents:
Includes reports and memoranda on the Biochemistry extension, F.H.S. Biochemistry and the microbiology unit and notice of a symposium on the design of teaching laboratories, organised by the RIBA for March 1958.

Building extension, 1955-64  CSAC 113.4.86/C.71  January-April 1958

Contents:
Includes 'Comments on the scheme for the Biochemistry Extension dated 17.3.58.' (5pp. typescript).

Building extension, 1955-64  CSAC 113.4.86/C.72  1959

Contents:
Includes memorandum (by R. Cecil) on the architects' short-comings in their planning of the extension. Sent to the Registrar by Krebs, 17 April.

Building extension, 1955-64  CSAC 113.4.86/C.73  1960

Contents:
Includes Building and Development Committee paper re revised estimate of cost and notes made by Krebs in case he should be requested to raise the money to meet the shortfall, July.

Building extension, 1955-64  CSAC 113.4.86/C.74  n.d

Contents:
Miscellaneous papers re Biochemistry department extension.

[no title or date]  CSAC 113.4.86/C.75-C.80

Contents:
Outside grants for Biochemistry department extension.

[no title or date]  CSAC 113.4.86/C.75-C.79

Contents:
Wellcome Trustees

Building extension, 1955-64  CSAC 113.4.86/C.75  1955

Contents:
Minute of visit from Sir Henry Dale, 28 November.

Building extension, 1955-64  CSAC 113.4.86/C.76  June 1956

Contents:
Minutes of discussions with Secretary of Wellcome Trustees, senior Biochemistry department staff and Registrar, and draft letter from the Registrar to Sir Henry Dale re possible grants from the Wellcome Trustees for the Biochemistry extension.

Building extension, 1955-64  CSAC 113.4.86/C.77  July-August 1956

Contents:
Correspondence with Sir Henry Dale re award of grant towards the cost of the projected new biochemistry building.

Building extension, 1955-64  CSAC 113.4.86/C.78  1957-60

Contents:
Includes copies of correspondence between the Registrar and Sir Henry Dale.

Building extension, 1955-64  CSAC 113.4.86/C.79  1963

Contents:
Brief correspondence re plaque to record formally in the building the indebtedness to the Wellcome Trust.

Building extension, 1955-64  CSAC 113.4.86/C.80  n.d

Contents:
J.R. Geigy, S.A.
1958-59
Correspondence re small contribution to Krebs's biochemical laboratories from Geigy and its British subsidiary.

Building extension, 1955-64  CSAC 113.4.86/C.81  1961-1964

Contents:
Typescript notes (6pp.) recording progress of building extension, 16 October 1961 to 11 June 1964.
Folder also includes 1p. typescript note: 'Comment on the following inscription in the entrance hall of the Department of Biochemistry'.

Building extension, 1955-64  CSAC 113.4.86/C.82  1959

Contents:
Newspaper cuttings re Biochemistry department architect, 1959.

Building extension, 1955-64  CSAC 113.4.86/C.83  1954

Contents:
Photographs of work in progress on the extension, with one earlier (1954) photograph.

[no title]  CSAC 113.4.86/C.84, C.85  2 May 1964

Contents:
Biochemistry extension open day

Building extension, 1955-64  CSAC 113.4.86/C.84  n.d

Contents:
Correspondence re arrangements, invitations, letters of thanks, etc.

Building extension, 1955-64  CSAC 113.4.86/C.85  [n.d.]

Contents:
Notes of arrangements, programme, press-cutting, draft of Krebs's speech at open day lunch.
Folder also includes draft of Krebs's speech at buffet luncheon, 14 January, for members of department, architects, consultants, builders, etc.

Sub-departments  CSAC 113.4.86/C.86-C.96  [n.d.]

[no title]  CSAC 113.4.86/C.86-C.93  1955, 1964-66


Related information: See also C.353.

Contents:
Iveagh Professorship of Chemical Microbiology
According to Krebs's own note preserved at C.89, the professorship was established in 1955 with outside support from Arthur Guinness & Sons, in the first instance for the expected tenure of the first professor, D.D. Woods, and after his death for the tenure of the second professor, J. Mandelstam. This support was sufficient to raise a readership to a professorship, to finance post-doctoral fellowships and contribute to general laboratory expenses. (Cf. Rem. & Refl., pp.204-5).

[no title]  CSAC 113.4.86/C.86-C.89  1955

Contents:
Correspondence and papers re the establishment of the Iveagh Professorship

Sub-departments  CSAC 113.4.86/C.86  1955

Contents:
May

Sub-departments  CSAC 113.4.86/C.87  1955

Contents:
June-July

Sub-departments  CSAC 113.4.86/C.88  1955

Contents:
September-November
Includes Krebs's note for the 'News and Views' columns of Nature on the appointment of D.D. Woods as Iveagh Professor.

Sub-departments  CSAC 113.4.86/C.89  1955

Contents:
Ms. and typescript notes by Krebs and D.D. Woods on the establishment of the Iveagh Professorship.

Sub-departments  CSAC 113.4.86/C.90  1964

Contents:
D.D. Woods's thoughts on Schedule A professors, March 1964, and paper on the Iveagh Professorship which Woods and Krebs discussed with the Secretary of the Faculties, July 1964.

[no title]  CSAC 113.4.86/C.91-C.93  1964

Contents:
Correspondence and papers re the future of the Chair after the death of D.D. Woods and the appointment of his successor, 1964-66.

Sub-departments  CSAC 113.4.86/C.91  1964

Contents:
Krebs's memorandum on the Iveagh Professorship, 21 November 1964, and correspondence about it with J.W.S. Pringle and B. Bleaney; second copy of memorandum incorporates Bleaney's comments.

Sub-departments  CSAC 113.4.86/C.92  1964-1965

Contents:
November 1964-January 1965

Sub-departments  CSAC 113.4.86/C.93  1966

Contents:
1966

[no title]  CSAC 113.4.86/C.94-C.96  1955-1963


Related information: See also C.346.

Contents:
Laboratory of Human Nutrition, 1955-59, 1963
The laboratory was incorporated in the Department of Biochemistry in 1955.

[no title or date]  CSAC 113.4.86/C.94, C.95

Contents:
Correspondence with H.M. Sinclair, Sir Henry Dale and the University Registry re future of the laboratory.

Sub-departments  CSAC 113.4.86/C.94  1955

Contents:
1955

Sub-departments  CSAC 113.4.86/C.95  1956, 1963

Contents:
1956, 1963

Sub-departments  CSAC 113.4.86/C.96  1955-1959

Contents:
Grant from Chilean Iodine Educational Bureau, 1955-59
Correspondence and report on work carried out under the grant (1956-57).

FUNDING AND ADMINISTRATION OF KREBS'S RESEARCH  CSAC 113.4.86/C.97-C.182  [n.d.]

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.97-C.123  [n.d.]

Arrangement: A chronological sequence of papers and correspondence.


Contents:
Most of the material presented here relates to a 1959 proposal to transfer the unit from the Medical Research Council to Oxford University, the future of the unit when Krebs retired from the Whitley Professorship and the move to and running of Krebs's 'retirement' quarters in the Radcliffe Infirmary, Oxford. The designation Metabolic Research Laboratory was adopted for these 'retirement' premises.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.97  1953-1961

Contents:
Medical Research Council Cell Metabolism Research Unit Progress Reports, 1953-57 and 1957-61.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.98  1954-1955

Contents:
Brief correspondence with University Registry re accommodation for MRC unit, 1954-55.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.99  1957-1972,nd

Contents:
Lists of MRC unit personnel, 1957-58, 1966, 1968, 1972 and n.d.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.100  1959

Contents:
Schedule and brief correspondence re visit by the Lord President of the Council, Lord Hailsham, to Oxford MRC units, 1959.

[no title or date]  CSAC 113.4.86/C.101-C.106

Contents:
Correspondence and papers re proposed transfer of MRC unit to Oxford University, 1959-61.
This 'major threat to the work of the Unit' came about in 1959 when the University Grants Committee in a report on university development suggested that the responsibility for some MRC units should be transferred to universities. In compliance with this policy the MRC asked Oxford University to enter into negotiations about the transfer of Krebs's unit. In the discussions with the General Board of the University it became clear that there were major difficulties in the way of a transfer including discrepancies between MRC and university salaries for a number of senior members of the unit and the financing of the unit as a whole after the ending of MRC support. Negotiations were abandoned after two and a half years of frustrating argument and Krebs concluded that the University as a body attached little importance to his unit's work (Rem. & Refl., pp.141-4).

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.101  January-April 1959

Contents:
Includes Krebs's memorandum on the proposed transfer of the MRC Unit in the Department of Biochemistry, 16 April.
(13pp. duplicated typescript including tables and appendices).

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.102  n.d

Contents:
Contents of envelope inscribed 'MRC Unit Transfer Staff Meeting'
Copy of Krebs's memorandum (8pp. duplicated typescript) and comments on it of eight senior members of the Biochemistry department.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.103  June-October 1959

Contents:
Includes copy of memorandum on salaries of university demonstrators (see also C.261), notes for meeting of Council, 5 October, and second memorandum on the proposed transfer of MRC Unit, 8 October.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.104  November-December 1959

Contents:
Includes part of the report of the Standing Committee for Natural Science (10 November 1959) as related to the proposed transfer, with Krebs's comments, and various drafts and copies of the second memorandum on the transfer.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.105  1960

Contents:
Includes draft of speech prepared by Krebs for meeting of Council, 29 October 1960, but not delivered.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.106  1961

Contents:
Papers

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.107  1963

Contents:
Brief correspondence re official visit of MRC to Oxford units

[no title]  CSAC 113.4.86/C.108-C.112  1965-67


Related information: See also C.353.

Contents:
Correspondence, etc., with the Medical Research Council and the University re the future of the MRC unit after Krebs reached the statutory age of retirement.
The material relates to Krebs's post-retirement plans, the future of his research team and the disposition of MRC equipment.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.108  1965

Contents:
Includes draft letter to Hebdomadal Council (not sent) on post-retirement activities.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.109  January-March 1966

Contents:
Papers

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.110  April-May 1966

Contents:
Includes draft statement 'Laboratory in the Nuffield Department of Medicine, Radcliffe Infirmary', 15 April, giving details of Krebs's research team, recent research interests, wish to continue research after retirement, etc.
The statement was probably the basis of a grant application to meet the costs of alterations to the laboratory in the Nuffield Department offered to Krebs by P.B. Beeson, Nuffield Professor of Clinical Medicine.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.111  June-August 1966

Contents:
Includes correspondence re the terms of the MRC's acceptance of Krebs's proposal for post-retirement research.

Medical Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.112  December 1966, September-October 1967

Contents:
Papers

[no title]  CSAC 113.4.86/C.113-C.123  1966-81

Contents:
Metabolic Research Laboratory, Radcliffe Infirmary

[no title or date]  CSAC 113.4.86/C.113-C.121

Contents:
Correspondence and papers re accommodation, equipment and the general running of the laboratory.

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.113  1966

Contents:
Material relates to the conversion into a biochemical research laboratory for Krebs of rooms vacated by the Department of Anaesthetics in the Nuffield Department of Clinical Medicine.

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.114  January-June 1967


Related information: See also C.122.

Contents:
Continuing correspondence on conversion of laboratory for Krebs.

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.115  July-December 1967

Contents:
Includes correspondence with the Registry re the University's acceptance of the MRC's offer of support for Krebs's research in the Nuffield Department of Clinical Medicine.

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.116  1968

Contents:
Papers

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.117  1970-72

Contents:
Includes request from Nuffield Department of Orthopaedic Surgery for advice on proposed research (1971) and Krebs's letter to the Director of the Committee on Invisible Exports setting out the invisible earnings of his research laboratory (1972).

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.118  1974

Contents:
Papers

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.119  1975-78

Contents:
1975 correspondence relates to the future of Krebs's research group.
1977 papers include 'Material for the renewal of the grant of the Medical Research Council', 5 and 6 April (6pp. typescript).

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.120  1979

Contents:
Includes material re possible move of the research group from the Radcliffe Infirmary to the John Radcliffe Hospital, Headington, Oxford.

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.121  1980-81 and nd

Contents:
Papers

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.122  1967-1967

Contents:
Grants to cover costs of converting accommodation into biochemical research laboratories.
J.R. Geigy, S.A. 1967-68
Nuffield Committee 1969

Material Research Council Unit/Metabolic Research Laboratory  CSAC 113.4.86/C.123  1969-80

Contents:
Staffing various dates

Financing bodies  CSAC 113.4.86/C.124-C.144  [n.d.]

Arrangement: Arranged in an alphabetical sequence (incomplete).



Related information: See also C.339.

Financing bodies  CSAC 113.4.86/C.124  1971

Contents:
National Institute of Alcoholism and Alcohol Abuse

[no title]  CSAC 113.4.86/C.125-C.128  1980-81

Contents:
Onassis Foundation
Correspondence and papers re Krebs's candidature for the Olympia Prize awarded by the International Board of the Onassis Foundation.
Krebs's name was put forward for the prize by Sir Michael Stewart.

Financing bodies  CSAC 113.4.86/C.125  December 1980-January 1981

Contents:
Papers

Financing bodies  CSAC 113.4.86/C.126  February-March 1981

Contents:
Includes draft statements about Krebs and his work by Krebs himself and Sir Michael Stewart.

Financing bodies  CSAC 113.4.86/C.127  April-June 1981

Contents:
Includes the statement of recommendation submitted to the International Board.

Financing bodies  CSAC 113.4.86/C.128  n.d

Contents:
Miscellaneous ms. and typescript material re Krebs's candidature.
Includes statement of honours received by Krebs.

[no title]  CSAC 113.4.86/C.129-C.139  1954-61, 1964-65, 1969, 1971, 1977

Contents:
Rockefeller Foundation
A chronological sequence of correspondence re grant applications, annual expenditure, visits from officers of Rockefeller Foundation to Oxford, etc.
Rockefeller Foundation support for Krebs's research, initiated in Germany in 1932, continued in Oxford until 1965.

Financing bodies  CSAC 113.4.86/C.129  December 1954

Contents:
Krebs's application for a grant to Oxford University for biochemical research under his direction, to replace the grant to Sheffield University returned on Krebs's acceptance of the Oxford Chair.
In his letter of 10 December Krebs explained what had happened to the equipment bought under previous grants at Sheffield.

Financing bodies  CSAC 113.4.86/C.130  1955

Contents:
In January Krebs was awarded a grant of up to $80,000 for a period of 5 years.

Financing bodies  CSAC 113.4.86/C.131  1956

Contents:
Papers

Financing bodies  CSAC 113.4.86/C.132  1957

Contents:
Papers

Financing bodies  CSAC 113.4.86/C.133  1958

Contents:
Papers

Financing bodies  CSAC 113.4.86/C.134  January-May 1959

Contents:
During this period Krebs made a major grant application to the United States Public Health Service and was advised by G.R. Pomerat, Associate Director of the Rockefeller Foundation, to await the outcome of this application before making a further request for Rockefeller funding.

Financing bodies  CSAC 113.4.86/C.135  September-December 1959

Contents:
In a letter of 6 November Krebs announced the award of a United States Public Health Service grant and discussed informally a further grant from the Rockefeller Foundation. Appendix I of this letter is a list of the permanent and semi-permanent staff of the Biochemistry department and Appendix II is a survey of current investigations.

Financing bodies  CSAC 113.4.86/C.136  1960

Contents:
In January Krebs made a formal application for a grant in support of research in the Oxford Biochemistry Department.

Financing bodies  CSAC 113.4.86/C.137  1961

Contents:
Papers

Financing bodies  CSAC 113.4.86/C.138  1964-65

Contents:
Papers

Financing bodies  CSAC 113.4.86/C.139  1969, 1971, 1977

Contents:
Papers

[no title]  CSAC 113.4.86/C.140-C.144  1976-82

Contents:
Travenol Laboratories Limited
Includes material re conferences as well as research funding.

Financing bodies  CSAC 113.4.86/C.140  1976-77


Related information: See also F.303.

Contents:
Conference on parenteral nutrition, Bermuda, 15-20 May 1977.
Correspondence with organisers re arrangements, publication of proceedings, etc. Bibliog. 364.

Financing bodies  CSAC 113.4.86/C.141  1978

Contents:
Correspondence and papers re financial support for research on parenteral nutrition.

Financing bodies  CSAC 113.4.86/C.142  1979

Contents:
Correspondence re parenteral nutrition research project and symposia at Oxford and Glasgow which Krebs was unable to attend.
Letter from Sir David Cuthbertson, 10 July, reflects on early penicillin research in light of G. Macfarlane's biography of Howard Florey.

Financing bodies  CSAC 113.4.86/C.143  1979-82

Contents:
Correspondence re possibility of a staff member studying for a doctorate in Krebs's laboratory and research funding.

Financing bodies  CSAC 113.4.86/C.144  1980

Contents:
Correspondence re research problems and Kiawah Island (South Carolina) symposium on branched chain amino and ketoacids.

Miscellaneous  CSAC 113.4.86/C.145-C.182  [n.d.]

Contents:
C.145-C.149 Home Office licences
C.150-C.157 Suppliers of research materials
C.158-C.182 Requests to visit/work in Krebs's laboratory

[no title]  CSAC 113.4.86/C.145  1954-81

Contents:
Home Office licences Various dates
Correspondence and papers re applications for and renewal of licences, statutory return of experiments, etc., for Krebs and his collaborators. For earlier material re Home Office licences see B.68.

Miscellaneous  CSAC 113.4.86/C.145  1954-67

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.146  1967-70

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.147  1971-72

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.148  1973-76

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.149  1978-81

Contents:
Papers

[no title]  CSAC 113.4.86/C.150-C.157  1954-80

Contents:
Correspondence with suppliers of scientific material for Krebs's research, presented in a chronological sequence. Not indexed. Similar material is sometimes included with the research projects in Section D.

Miscellaneous  CSAC 113.4.86/C.150  1954-58

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.151  1960-67

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.152  1968(1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.153  1968(2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.154  1969

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.155  1970-71

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.156  1973-76

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.157  1977-80

Contents:
Papers

[no title or date]  CSAC 113.4.86/C.158-C.182

Contents:
Correspondence re requests to visit or work in Krebs's laboratory, arranged in a chronological sequence. There is similar material in the correspondence folders.

Miscellaneous  CSAC 113.4.86/C.158  1954-55

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.159  1956-57

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.160  1958

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.161  1960

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.162  1961

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.163  1962-64

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.164  1965-67

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.165  1967-68

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.166  1969

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.167  1970 (1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.168  1970 (2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.169  1971

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.170  1972 (1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.171  1972 (2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.172  1973 (1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.173  1973 (2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.174  1973 (3)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.175  1974 (1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.176  1974 (2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.177  1975 (1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.178  1975 (2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.179  1976 (1)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.180  1976 (2)

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.181  1977

Contents:
Papers

Miscellaneous  CSAC 113.4.86/C.182  1978-81

Contents:
Papers

DEVELOPMENT OF SCIENCE AT OXFORD  CSAC 113.4.86/C.183-C.240  [n.d.]

Administrative history:
During Krebs's tenure of the Whitley Professorship, he worked for a strengthening of the sciences at Oxford and his interest and involvement in this, especially in respect of the biological sciences, is attested by the very substantial body of correspondence and papers presented here. As a member of the Board of the Faculty of Biological Sciences Sub-Committee on the Development of Biology he took part in discussions on the establishment of new departments (C.183-C.189) and when the new quinquennial grant proved inadequate for the developments envisaged, played a leading role in informal discussions within the university on alternative sources of finance (C.190-C.201). There is material re a proposed Biology Centre (C.202-C.204) and the difficulties faced by the new Linacre Professor of Zoology, J.W.S. Pringle, in respect of the provision of adequate accommodation for him by the university (C.205-C.211).
Perhaps the development to which Krebs attached the most significance, however, was the establishment of molecular biophysics at Oxford (C.212-C.236) not only because of the inherent importance of the subject but also because he believed that the difficulties which had to be overcome before the successful establishment of the Laboratory of Molecular Biophysics in 1967 were characteristic of most major innovations in the university. The papers presented here chart the contribution of Krebs and J.W.S. Pringle to the establishment of the new laboratory and include copies of Pringle's own papers (C.219-C.227) made available as source material for Krebs's very substantial unpublished account of the history of molecular biology at Oxford. (see C.229-C.234). Krebs provided an interesting but much shorter account in his autobiography (Rem. & Refl. pp.207-213). There is also a draft article on the same subject for the Oxford Magazine (C.228).
For published accounts by others which touch upon some of these questions see D.C. Phillips's memoir of W.L. Bragg (Biographical Memoirs of Fellows of the Royal Society, 25, 1979) and V. Wigglesworth's memoir of J.W.S. Pringle (Biographical Memoirs of Fellows of the Royal Society, 29, 1983).
For Pringle's own account see the copy of his lecture on Oxford Zoology at C.211.

Development of Biology, 1956-58  CSAC 113.4.86/C.183-C.189  1956-58


Related information: At a later date these papers were shown to J.W.S. Pringle. See C.183.

Contents:
Correspondence and papers re the Board of the Faculty of Biological Sciences Sub-Committee on the Development of Biology.
The Chairman of the Sub-Committee was C.D. Darlington.

Development of Biology, 1956-58  CSAC 113.4.86/C.183  1956-1957

Contents:
'Memorandum from Professor Darlington: New Biology Departments', 20 November 1956.
2pp. duplicated typescript.
'Expansion of Biology in Oxford', 2 February 1957.
3pp. typescript memorandum by D.D. Woods.
Carbon of letter from W. Le Gros Clark to Darlington, 4 February 1957, with comments on Darlington's memorandum and points for his committee to consider.
Minutes of the meeting of the committee on the development of biology, 4 February 1957.
4pp. typescript.
Krebs attended this meeting.

Development of Biology, 1956-58  CSAC 113.4.86/C.184  1957

Contents:
Letter from D.D. Woods, 13 February 1957, enclosing two drafts of a document about a new department of chemical/general microbiology. Only one draft, described as the shorter version, was found with the letter.
Committee paper for meeting of 19 February 1957.
3pp. duplicated typescript.
Incorporates the longer version of Woods's memorandum on a new microbiology department and a memorandum by A.G. Ogston on physical biochemistry.
Copy of memorandum from W.O. James on the establishment of a department of plant physiology.
2pp. typescript, with covering letter, 21 February 1957.
Copy of draft preamble 'which might contain suitable material for the report on the development of biology'.
2pp. typescript, with covering letter.
Sent to Darlington by Krebs, 28 February 1957.
Memorandum on virology by K. Burton.
1p. duplicated typescript.

Development of Biology, 1956-58  CSAC 113.4.86/C.185  1957

Contents:
Committee papers for meetings of 6 and 26 March 1957.
Includes:
Memorandum by Professor Burn on a New Department of Experimental Medicine.
Memorandum by Professor Darlington on a Department of Genetics.
Comments of Professor Pickering on Professor Burn's memorandum on a New Department of Experimental Medicine.
Memorandum by Professor Sir Wilfrid Le Gros Clark: Biological Science in Oxford: The case for a Department of Human Biology and Physical Anthropology.
Memorandum by Professor Sir Howard Florey on a new department of Medical Bacteriology.

Development of Biology, 1956-58  CSAC 113.4.86/C.186  1957

Contents:
Memorandum on the relations of biology with the physical sciences by C.D. Darlington, 1 April 1957.
2pp. typescript.
Comments by A.G. Ogston on Darlington's memorandum, 7 April 1957.
3pp. typescript (carbon).
Letters from R. Barer to Krebs, 11 and 12 April 1957, commenting on the memoranda by Darlington and Ogston.
Paper on biophysics by Barer and Ogston, n.d
4pp. typescript (carbon).
Draft statement on growing points of biology and medicine.
6pp. typescript.
Sent to Krebs by J.H. Burn.
Draft for 'Preamble' by Darlington, 24 April 1957, and Krebs.

Development of Biology, 1956-58  CSAC 113.4.86/C.187  1957

Contents:
Committee papers and correspondence re meetings of 2 and 31 May 1957.
Includes:
Memorandum by N.T.J. Bailey on a new department of Biometry.
Statements on Virology by Sir Macfarlane Burnet and K.M. Smith.
Copies of interim report of sub-committee and preamble.

Development of Biology, 1956-58  CSAC 113.4.86/C.188  1957

Contents:
'Notes on the development of science and medicine at Oxford', 27 September 1957.
1p. duplicated typescript. By Krebs.
Untitled 3pp. typescript draft re conclusions of sub-committee and discussions with Chairman of the University Grants Committee by two of its members. n.d. but probably late 1957.
'Biology development', 25 November 1957.
1p. typescript note. By Darlington.
Draft statement on growing points of biology and medicine, 23 December 1957.
3pp. duplicated typescript, with ms. note 'this contains ammunition, but is not a suitable call for action'.

Development of Biology, 1956-58  CSAC 113.4.86/C.189  1957-1958

Contents:
Committee papers for meeting of 28 May 1958:
Minutes of last meeting of 31 May 1957.
Report of Committee on the future of the Physical Sciences in Oxford, 19 January 1958.
Memorandum from Professor L.R. Wager: 'Developments in the Geological Sciences - Proposals for Departments or Sub-Departments of Geophysics, Geochemistry and Geomorphology'.
Copy of report of the sub-committee on the Development of Biology and Medicine. Virtually identical with interim report at C.187.

'Oxford's needs in science', 1957-61.  CSAC 113.4.86/C.190-C.201  1957-61


Related information: See also C.338.

Contents:
Correspondence and papers re informal discussions within the university arising from what was considered the inadequacy of the new quinquennial grant for providing much-needed scientific and other development at Oxford. Discussions centred on identifying the particular areas of science for development and the desirability of a public appeal to help finance them.
In addition to Krebs, the principal participants were:
B. Bleaney
Lord Bridges
A.L.C. (later Lord) Bullock
J.H. Burn
C.D. Darlington
Sir William Deakin
H.W. (later Lord) Florey
E.R.H. (later Sir Ewart) Jones
D. (later Sir Douglas) Veale
L.R. Wager
In April 1958 a memorandum on Oxford's needs in science was sent by Krebs to the Vice-Chancellor for consideration by Council. Apparently there was no action at the time because of the appeal for St. Catherine's College, though Krebs made an informal approach for financial support for Oxford science to British Petroleum, which came to nothing.
In 1960 Krebs approached the Wellcome Foundation re funding for the type of development envisaged in the memorandum on Oxford's needs in science. Although encouraged by the Foundation to make a proposal in respect of the biological sciences he had been unable to do so by late 1961 because of the uncertainty of suitable building sites.

'Oxford's needs in science', 1957-61.  CSAC 113.4.86/C.190  June-July 1957

Contents:
On 8 July a meeting was held at Corpus Christi College to consider whether industry, commerce and private individuals should be approached for money for university development.
Folder includes the notes Krebs prepared in advance of the meeting - 'not used since Registrar organised discussion in his own way' - and an account, also by Krebs, of what took place at the meeting.
Krebs agreed to provide a statement outlining the king of developments in biology and medicine for which any funds collected might be used.

'Oxford's needs in science', 1957-61.  CSAC 113.4.86/C.191  August-September 1957

Contents:
Includes letter (September) from J.M. Hammersley on how industrialists would react to a general request to finance extensions of academic work at Oxford and what kind of cooperation would be needed between industry and the universities in the future.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.192  October-December 1957

Contents:
Includes notes of discussions on 1 October and 22 November and drafts of ideas on growing points of biology and medicine.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.193  January-February 1958

Contents:
Includes statement on growing points in Geology and related sciences, note of discussions on 24 January, draft statement of Oxford's needs in science, 30 January, and notes on and drafts of letter to The Times.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.194  April 1958

Contents:
Includes drafts of covering note and memorandum on Oxford's needs in science sent to the Vice-Chancellor 22 April, for consideration by Council.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.195  May 1958

Contents:
Two drafts of Krebs's statement at Council meeting, 5 May

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.196  June 1958

Contents:
Includes material re meeting at the British Petroleum Company Offices about fund-raising for a new college (St. Catherine's), 10 June, and subsequent approach to a director of BP, Sir Percival Waterfield, about support for scientific development at Oxford from the oil company.
Folder also includes additions to the memorandum of 25 May 1958 on the developments in the geological sciences, 16 June. By L.R. Wager.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.197  July 1958

Contents:
Includes material re meeting between representatives of the University, including Krebs, and the Chairman of the University Grants Committee, Sir Keith Murray, and Krebs's approach to BP for financial support for Oxford science.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.198  1959-60

Contents:
Note of discussions between Krebs and Registrar re external financial support for scientific development, 19 September 1959.
Brief exchange between Krebs and Sir George Pickering, re a copy of the memorandum on Oxford's needs in science for Sir Harold Himsworth, October 1959.
Brief exchange between Krebs and L.R. Wager re earlier correspondence relating to possible financial support from BP, May 1960.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.199  April-May 1960

Contents:
Material re meeting between Krebs and Wellcome Trustees, 28 April, about possible financial support for the development of the growing points of science at Oxford, as set out in the memorandum on Oxford's needs in science.
Includes draft notes on research laboratories for developing the growing points of science and new biological laboratory.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.200  October-November 1961

Contents:
Brief correspondence re Wellcome Trust funding for proposed Biological Sciences Centre.

'Oxford's needs in science', 1957-61  CSAC 113.4.86/C.201  [n.d.]

Contents:
Undated ms. and typescript notes and drafts found with Oxford's needs in science material.

Biology Centre, 1962  CSAC 113.4.86/C.202-C.204  1962

Contents:
Correspondence and papers re the Board of the Faculties of Medicine and Biological Sciences Committee on the proposed Biology Centre.

Biology Centre, 1962  CSAC 113.4.86/C.202  1962

Contents:
February
Includes a summary of the previous history of the question.

Biology Centre, 1962  CSAC 113.4.86/C.203  1962

Contents:
March
'Memorandum on the proposed biology centre', 1 March. By J.W.S. Pringle.
2pp. typescript.
'Memorandum on the Biology Centre'. By G.C. Varley.
2pp. typescript.
'Notes on the Biological Centre'. By G.L.B[rown].
3pp. typescript.
'Further note on the Biology Centre'. By J.W.S. Pringle.
1p. duplicated typescript.
Memorandum of points to be decided, 9 March, By Krebs.
3pp. typescript.
'Points for Discussion', 15 March. By C.D. Darlington.
2pp. typescript.
'Note on the proposed Biology Centre', 15 March. By G.W. Pickering.
1p. typescript.
Draft note of points for discussion, 16 March. By Krebs.
2pp. typescript.
Draft note of 'Dinner and committee meeting of biological centre', 19 March. By Krebs.
2pp. typescript.

Biology Centre, 1962  CSAC 113.4.86/C.204  1960; 1962


Related information: See CSAC 113/C.199.

Contents:
April-June
Draft report of the committee on the proposed Biological Centre by G.C. Varley and related correspondence.
Also found with this material is a copy of a letter from Sir Henry Dale, 29 April 1960, re possible Wellcome funding for Oxford scientific development.

Zoology  CSAC 113.4.86/C.205-C.211  1961-1979

[no title or date]  CSAC 113.4.86/C.205-C.210

Contents:
'Historical Documents regarding John Pringle'
Contents of a folder so inscribed divided into six folders for ease of reference.
The material relates to Pringle's appointment as Linacre Professor of Zoology, new accommodation for the Zoology department, the development of Zoological research in Oxford, etc.

Zoology, 1961-79  CSAC 113.4.86/C.205  January-March 1961

Contents:
Papers

Zoology, 1961-79  CSAC 113.4.86/C.206  September-December 1961

Contents:
Papers

Zoology, 1961-79  CSAC 113.4.86/C.207  February 1962

Contents:
Includes material re candidates for readership in biophysics, 2pp. duplicated statement by the Vice-Chancellor, A.L.P. Norrington, on the Zoology building and 'Resolution on allocation of site for Zoology building', 4pp. typescript statement addressed to members of Congregation by J.R. Baker, W. Holmes and N. Tinbergen.

Zoology, 1961-79  CSAC 113.4.86/C.208  May-July, November 1962

Contents:
Includes 3pp. typescript statement by Pringle entitled 'Crisis in Oxford', with Krebs's ms. comments.

Zoology, 1961-79  CSAC 113.4.86/C.209  1963

Contents:
Includes material re the development of biophysics and insect physiology research in the Zoology department.

Zoology, 1961-79  CSAC 113.4.86/C.210  1964-67

Contents:
Papers

Zoology, 1961-79  CSAC 113.4.86/C.211  'Oxford Zoology 1961-79'

Contents:
20pp. duplicated typescript with ms. note, 'John Pringle. Unpublished script of lecture given in June 1979 on his retirement'.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.212-C.236  [n.d.]

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.212  1956

Contents:
Material re possible transfer of J.T.Randall's biophysics unit from King's College, London, to Oxford.
Folder includes copy of the Medical Research Council Progress Report of Randall's biophysics unit for 1951-55.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.213  1958

Contents:
Material reflecting Krebs's continued interest in the further development of biophysics at Oxford.
He discussed the question with D.M.C. Hodgkin and sought the advice of M.F. Perutz.
Folder includes information re D.C. Phillips and copy of the Medical Research Council Progress Report of the Cavendish Laboratory Molecular Biology Research Unit, for 1956-58.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.214  1962

Contents:
Krebs's typescript notes of discussions with D.C. Phillips, D.M.C. Hodgkin and senior members of the biochemistry department re possible transfer of Phillips and his collaborators from the Royal Institution to Oxford, September and October.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.215  January-May 1963

Contents:
Material re possible transfer of Phillips and his unit to Oxford, including exchanges of correspondence between Krebs and J.W.S. Pringle, Krebs and Phillips, Pringle and Sir Harold Himsworth.
Considerations included the availability of accommodation in the new Zoology building and the date of retirement of Sir Lawrence Bragg, Director of the Royal Institution.
Much of the material is photocopies.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.216  June-December 1963

Contents:
June material relates to a meeting of Krebs and Pringle with Bragg to discuss the transfer of the biophysics unit to Oxford upon Bragg's retirement in 1967. Krebs hoped that Phillips and his group would do some lecturing in Oxford before that date.
In September Krebs wrote to Himsworth to arrange a meeting to discuss further the future of molecular biophysics in Oxford and this meeting was held at MRC headquarters in October.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.217  1964, 1965

Contents:
1964 correspondence relates to lecture course by Phillips at Oxford during the Trinity term.
1965 correspondence relates to Phillips's discourse at the Royal Institution, 5 November.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.218  1966

Contents:
Includes letter from Phillips thanking Krebs for his part in making possible the move of Phillips and his team to Oxford and inviting Krebs to give an evening discourse at a Summer School on Molecular Biology and Biophysics to be held in Oxford 18-29 September.

[no title]  CSAC 113.4.86/C.219-C.227  1964-67

Contents:
Photocopies of documents re detailed arrangements for D.C. Phillips and his biophysics research unit to come to Oxford from the Royal Institution
These documents are the correspondence and papers of J.W.S. Pringle re negotiations with Oxford University, D.C. Phillips, the Medical Research Council, Nuffield Foundation, etc.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.219  March-June 1964

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.220  July-December 1964

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.221  January-April 1965

Contents:
Includes letter from Sir Harold Himsworth to the University Registrar with the news that Phillips and his team had 'got out the structure of lysozyme' and that Sir Lawrence Bragg had provided a champagne celebration.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.222  May-June 1965

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.223  July-August 1965

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.224  October-November 1965

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.225  December 1965

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.226  January 1966

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.227  March-July 1966, August 1967

Contents:
Papers

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.228  1966

Contents:
'Molecular biophysics at Oxford'
6pp. typescript draft, with slight ms. correction, intended for publication in the Oxford Magazine.
Copies of letters from Krebs to J.W.S. Pringle and D.C. Phillips, May 1966, enclosing draft of proposed article. For Pringle's reply see C.210.
1966 Hilary 7 issue of the Oxford Magazine in which the editor attributed the establishment of Molecular Biology entirely to the University administration.
It was this editorial comment which prompted Krebs to draft his article.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.229-C.231  n.d

Contents:
'Documents Concerning the History of Molecular Biophysics at Oxford'
Typescript draft with ms. corrections and additions. Paginated pp.I-II, 1-102, including some original documents. The pagination is not continuous, presumably because Krebs intended to add further documents at a later date.
Krebs's preface (p.II) explains the nature of the documents:
'This is a collection of letters, of minutes of personal discussions, and of University papers, especially of the Board of Biological Sciences, linked by comments.
It is not a complete collection of material bearing on the history of the Laboratory of Molecular Biophysics. It includes only those aspects with which I was personally concerned as a participant or witness. The material is in a rough draft form. It requires editing and in some places checking of facts.'
The typescript is divided into three folders for ease of reference.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.232-C.234  n.d

Contents:
'Documents concerning the History of Molecular Biophysics at Oxford'
Clean typescript copy of the preceding divided into three folders for ease of reference.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.235  n.d

Contents:
'Comments on the difficulties to keep Oxford science up to date, with reference to the history of Oxford science'
Typescript draft with ms. corrections, paginated pp. 111a-123. Also clean typescript copy of the same.
The 'Comments' were a continuation or conclusion for the 'Documents'.
Krebs considered that the difficulties which had to be overcome to establish Molecular Biophysics at Oxford University were characteristic of the great majority of major innovations. He gave earlier examples of the struggles necessary to keep Oxford science up to date: the establishment of the University Museum, the Whitley Professorship of Biochemistry, the Clinical School, and the department of Nuclear Physics.

Molecular Biophysics, 1956, 1958, 1962-67  CSAC 113.4.86/C.236  n.d

Contents:
Miscellaneous typescript drafts re Molecular Biophysics.

Miscellaneous  CSAC 113.4.86/C.237-C.240  1956, 1959-61

Miscellaneous  CSAC 113.4.86/C.237  1956

Contents:
Debate in Congregation re resolution on the Keble Road Triangle development, 4 December 1956.
Copy of statement of proposer, P.D. Henderson, as sent to Krebs, with ms. note explaining why p.2 was missing.
Draft of Krebs's speech seconding the resolution.
Newspaper cuttings.

[no title]  CSAC 113.4.86/C.238, C.239  1962-67

Contents:
Quinquennial Application

Miscellaneous  CSAC 113.4.86/C.238  1959-1960

Contents:
Krebs's notes of meeting of sub-committee considering policy for next quinquennium, 16 December 1959.
1p. typescript and 1p. draft.
Memorandum on postgraduate education by G.W. Pickering, with brief related correspondence, February 1960.
Krebs's notes for meeting of Natural Sciences Committee of the General Board, 16 February 1960.
4pp. typescript, with a few ms. additions and corrections.
Interim report of Faculty Board of Biological Sciences Committee on Quinquennial Estimates. n.d.
4pp. typescript.

Miscellaneous  CSAC 113.4.86/C.239  1960-1967

Contents:
Board of the Faculty of Biological Sciences. Faculty expenditure: Quinquennial Application 1962-67.
2pp. duplicated typescript and appendices of statements by heads of department including Krebs.
The appendices are dated in February and March 1960.
Statements made by representatives of the Committee of Heads of Science Departments (including Krebs) at the discussions with the University Grants Committee on 9 November 1960.
3pp. duplicated typescript.

Miscellaneous  CSAC 113.4.86/C.240  1961

Contents:
New university science building.
'The problem of planning university laboratories', 7 June 1961.
3pp. duplicated typescript and 6pp. typescript draft with ms. corrections.
The memorandum was prepared by R. Cecil, drawing on the experience of the Biochemistry Department in respect of its new extension.
'Planning of University Buildings', 7 July 1961.
2pp. typescript note of discussions. By Cecil.
'Comments on Messrs. Chamberlin, Powell and Bon's plan for the development of the Science Area'
4pp. typescript memorandum by Cecil, with covering letter from Krebs to the Registrar, 13 October 1961.

UNIVERSITY REFORM  CSAC 113.4.86/C.241-C.334  [n.d.]

Administrative history:
Although Krebs begins the chapter of his autobiography on Oxford by praising the university as 'in many ways a splendid place for academics, one of the finest in the world' (Rem. & Refl., p.193), he was also very conscious of its shortcomings and his involvement in attempts to rectify these is evidenced by the substantial body of surviving material presented here.
It is divided into a chronological sequence of general papers and correspondence on various aspects of Oxford reform and further sequences of papers on particular areas for reform such as university salaries and schedule A professors and on specific committees or commissions of inquiry.
For Krebs's articles on reform written for the Oxford Magazine, see C.329-C.334.

Contents:
With an introductory note
C.241-C.260 General correspondence and papers
C.261-C.273 Salaries
With an introductory note
C.274-C.278 Schedule A Professorships
C.279-C.328 Committees and Commissions of Inquiry
C.329-C.334 Publications
C.335-C.389 GENERAL UNIVERSITY CORRESPONDENCE
C.335-C.361 Central administration
C.362-C.372 Electoral Boards
C.373-C.389 Libraries, departments, colleges and societies
For correspondence and papers re Krebs's election to the Whitley Professorship of Biochemistry, see A.555-A.566.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.241-C.260  [n.d.]

Contents:
The material is principally Krebs's dated typescript notes, but includes correspondence with the Registry and others, newspaper cuttings and other background material.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.241  1958

Contents:
Note by C.D. Darlington for the Visitorial Board on the demands for lecturing made upon visiting professors, 19 March.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.242  1961

Contents:
Includes undated notes found with 1961 material.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.243  January-May 1962

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.244  June 1962

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.245  September 1962

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.246  March-June 1963

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.247  July-December 1963

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.248  January-April 1964

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.249  June-October 1964

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.250  1965

Contents:
Includes draft of memorandum on improving communication within the university and between the university and the outside world.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.251  1966

Contents:
'The difficulties in attracting staff in certain science subjects'
3pp. typescript draft, with related newspaper cuttings.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.252  July-August 1967

Contents:
'Thoughts on occasion of retirement'
Intended as memorandum to General Board but never completed.
This is a sequence of mainly typescript notes setting out Krebs's views on the inability of the General Board, as then constituted, to foster excellence within the university, especially scientific excellence.

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.253  September-December 1967

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.254  1968

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.255  1969-70

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.256  1973, 1979

Contents:
Papers

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.257  n.d

Contents:
Miscellaneous undated ms. and typescript notes

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.258, C.259  1958-61

Two folders.

Contents:
Miscellaneous press-cuttings on various aspects of university reform and development including salaries

General correspondence and papers, 1958, 1961-68, 1973, 1979  CSAC 113.4.86/C.260  mid-1960s

Contents:
Press-cuttings on misgovernment and maladministration inside and outside the universities

Salaries, 1959-61  CSAC 113.4.86/C.261-C.273  [n.d.]


Related information: For drafts of the Oxford Magazine articles and related correspondence see C.329-C.334.
See also C.342-C.345, C.349-C.352.

Administrative history:
Krebs identifies in his autobiography (Rem. & Refl., pp. 196-201) a number of problems relating to salary and income structure within the university, especially:
(1) the existence in the science departments of two classes of lecturer, those who enjoyed, in addition to their full-time university lecturership, a tutorial College Fellowship which brought considerable benefits in terms of income, status and amenities, and those who were without the all-important college attachment.
(2) the rigid age-tie of the salary scale and the absence of the grade of Senior Lecturer which made it impossible, Krebs argued, to recognise special merit by more rapid promotion, or promotion to a higher grade.
Krebs first raised the question of abolishing the age-scale in October 1959 but although he had the support of the Faculty Board of Biological Sciences concerned about the effect of the salary-income structure on the recruitment and retention of good staff, the General Board decided against action. Hopes for movement in the direction Krebs wished the university to go came in May 1960 with a government decision to make funds available through the University Grants Committee to universities which were having difficulty in attracting or retaining academic staff of requisite quality. Oxford was offered £14,500, 'to recoup... expenditure incurred in paying salaries above the normal in order to recruit or retain staff'.
While the university authorities considered the offer, a committee of Heads of Science Departments, on which Krebs played the leading role, collected detailed information on the difficulties in staffing certain departments - information which formed the basis of a memorandum submitted to the General Board on 21 October 1960. The General Board recommended the rejection of the offer of money. Krebs openly challenged this recommendation in an article for the Oxford Magazine published 1 June 1961 and he was supported in this public campaign by an article in the following week's edition in which an anonymous demonstrator described how those without college affiliations were treated as 'useful second-class citizens' - Krebs had a hand in drafting this second article. Despite these efforts Congregation voted on 13 June to turn down the offer of the University Grants Committee.
Krebs was reluctant to give up the fight over the university salary-income structure and published a further article in the Oxford Magazine in October 1961 in which he set out the inequalities between the incomes of Fellows and Non-Fellows. Although the article did not give rise to any action, the matters which concerned Krebs were considered by the Robbins Committee on Higher Education and the Franks Commission of Inquiry (qqv.). Krebs retained his interest in these questions over an extended period.

Contents:
The papers, which include correspondence with the university authorities and academic colleagues, drafts of memoranda for the General Board, drafts of Krebs's speeches at the Hebdomadal Council and at Congregation, etc., are presented in a chronological sequence.

Salaries, 1959-61  CSAC 113.4.86/C.261  1959

2 copies.

Contents:
Includes Krebs's memorandum for the Biology Board on the salaries of university demonstrators

Salaries, 1959-61  CSAC 113.4.86/C.262  February, May 1960

Contents:
Includes note of Krebs's remarks on salary supplementation at a meeeting of the Hebdomadal Council, 22 February.

Salaries, 1959-61  CSAC 113.4.86/C.263  June 1960

Contents:
Includes letter from Krebs to the President of Trinity College (A.L.P. Norrington), with information re the question of special supplementation of Demonstrators' salaries, note by Krebs on the UGC offer of flexibility money and two annotated copies of a memorandum on quinquennial policy, 1962-67, for consideration by Heads of Science Departments in respect of the visit of the UGC to Oxford, November 1960. Krebs kept the UGC material with that relating to salaries although it includes additional topics.

Salaries, 1959-61  CSAC 113.4.86/C.264  July 1960

Contents:
Heads of Science Departments sub-committee on salary scales (1).
The members of the sub-committee were Krebs, G.E. Blackman and E.R.H. (later Sir Ewart) Jones.
Folder includes drafts of circular sent by sub-committee requesting information about the adequacy of present salary scales in attracting and retaining first-rate staff. There are replies from Sir Alister Hardy, C. Clark, W.D.M. (later Sir William) Paton, H.W. (later Lord) Florey and others.

Salaries, 1959-61  CSAC 113.4.86/C.265  October 1960

Contents:
Heads of Science Departments sub-committee on salary scales (2).
Replies to the sub-committee's circular from C.D. Darlington, D.H. Wilkinson and A. Thom, Krebs's ms. and typescript notes on the replies, duplicated statement of comments on the adequacy of university demonstrator scales and some (undated) background material on university salaries.

Salaries, 1959-61  CSAC 113.4.86/C.266  November 1960 (1)

Contents:
Visit of Medical Sub-committee of the UGC to Oxford, 8 November 1960.
Brief correspondence, programme of visit, draft statements by Krebs on postgraduate education and research.

Salaries, 1959-61  CSAC 113.4.86/C.267  November 1960 (2)

Contents:
Visit of UGC to Oxford, 9 November 1960.
Various drafts, notes on background material, etc., put together by Krebs re UGC visit.
Folder includes draft for Krebs's speech at UGC meeting, duplicated note on the discussion with the UGC for Committee of Heads of Science Departments and draft letter from Krebs and B. Bleaney (probably to the editor of the Oxford Magazine) re meeting between UGC and Heads of Science Departments.

Salaries, 1959-61  CSAC 113.4.86/C.268  December 1960

Contents:
Includes draft speech for Council meeting, 12 December, 'not delivered because item was adjourned', and draft of substantial paper by Krebs on the salaries of university demonstrators and lecturers: 'Comments bearing on the University Grants Committee's offer of selective supplementation and the General Board's proposal that the offer be rejected'.

Salaries, 1959-61  CSAC 113.4.86/C.269  January-April 1961

Contents:
Includes duplicated typescript copy of Krebs's memorandum on the salaries of university demonstrators and lecturers and drafts of Krebs's speeches on the same subject at meetings of Council and Congregation.

Salaries, 1959-61  CSAC 113.4.86/C.270  May 1961 (1)

Contents:
'Notes on the use of flexibility'
1p. duplicated typescript, 1 May, attached to 'Corrected Copy' of Krebs's paper on the salaries of university demonstrators and lecturers.
Photostat of report of standing committee on finance, 2 and 9 May, with record of interview of Krebs by the committee.
'Flexibility within the lecturers' scale: Communication from the General Board of the Faculties', 13 May.

Salaries, 1959-61  CSAC 113.4.86/C.271  May 1961 (2)

Contents:
Draft notes for meeting of Council and correspondence with academic colleagues, the Registry and the UGC.

Salaries, 1959-61  CSAC 113.4.86/C.272  June-July 1961

Contents:
Includes correspondence with the Registrars of Oxford and Sheffield Universities, copy of Oxford University Gazette with agenda for 13 June meeting of Congregation and Krebs's typescript note, heavily corrected, on the vote of Congregation on 'flexibility' funds.

Salaries, 1959-61  CSAC 113.4.86/C.273  n.d

Contents:
Printed university papers re salaries' question.

Schedule A Professorships, 1961-64  CSAC 113.4.86/C.274-C.278  [n.d.]


Related information: See CSAC 113.4.86/C.86-CSAC 113.4.86/C.89.

Administrative history:
Krebs advocated the replacement of the pyramidal structure of the large Oxford Science departments by the multi-professor type of departmental organisation he had admired in America (Rem. & Refl., pp.203-207).
The material includes correspondence, committee papers and Krebs's typescript notes and drafts.
For the creation of a second Professorship in Krebs's own department

Schedule A Professorships, 1961-64  CSAC 113.4.86/C.274  March-July 1961

Contents:
Papers

Schedule A Professorships, 1961-64  CSAC 113.4.86/C.275  August-September 1961

Contents:
Includes notes on the selection of demonstrators.

Schedule A Professorships, 1961-64  CSAC 113.4.86/C.276  October 1961

Contents:
Papers

Schedule A Professorships, 1961-64  CSAC 113.4.86/C.277  1962-63

Contents:
Papers

Schedule A Professorships, 1961-64  CSAC 113.4.86/C.278  February-June 1964

Contents:
Includes undated ms. note by D.D. Woods: 'Some ill-digested random points re Professors. (Transatlantic reading).'

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.279-C.328  [n.d.]

Contents:
C.279-C.281 Committee on the relations between Colleges and the University
C.282-C.291 Robbins Committee on Higher Education
C.292-C.297 National Incomes Commission
C.298-C.328 Franks Commission of Inquiry

[no title or date]  CSAC 113.4.86/C.279-C.281

Contents:
Committee on the relations between Colleges and the University, 1961-63
The material, principally Krebs's typescript notes reflecting on matters affecting relations between the Colleges and the University, is presented in a chronological sequence.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.279  1961

Contents:
Includes copy of memorandum expressing the views of about 130 members of Congregation with full-time university, departmental or institutional appointments who were not Fellows of Colleges, November.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.280  1962

Contents:
Includes 'Report of the Syndicate on the Relationship between the University and Colleges', Cambridge University Reporter, 13 March, annotated by Krebs.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.281  1963 and nd

Contents:
Papers

[no title or date]  CSAC 113.4.86/C.282-C.291

Contents:
Robbins Committee on Higher Education, 1961-63

[no title or date]  CSAC 113.4.86/C.282, C.283

Contents:
Correspondence with University Registry, Robbins Committee, academic colleagues, re memorandum prepared by Krebs, Krebs's oral evidence to the committee, etc.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.282  1961-62

Contents:
Papers

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.283  1963

Contents:
Papers

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.284  n.d

Contents:
Early drafts of Krebs's memorandum to Robbins Committee.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.285  January 1962

Contents:
'Complete' draft of Krebs's memorandum
9pp. typescript draft, with six appendices.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.286  January 1962

Contents:
Draft of Krebs's memorandum with ms. comments of H.W. (later Lord) Florey and letter from Florey returning the draft
Clean typescript copy of the memorandum

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.287  23 February 1962

Contents:
Krebs's verbatim evidence taken before the committee
5pp. duplicated typescript and 1p. ms. corrections.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.288  1961-62

Contents:
Krebs's dated typescript and ms. notes on aspects of university reform especially the relationship between the colleges and the university

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.289  n.d

Contents:
Miscellaneous ms. notes re Robbins Committee.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.290  n.d

Contents:
Submissions to the Robbins Committee by others:
Agricultural Research Council
Association of University Teachers
Committee of Vice-Chancellors and Principals of the Universities of the United Kingdom
The Institute of Physics and the Physical Society

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.291  December 1961

Contents:
Miscellaneous newspaper cuttings and printed material re various aspects of university reform and development including salaries, found with Robbins Committee papers.
Folder includes Commonwealth Relations Office Seventh Report of the Overseas Migration Board

[no title]  CSAC 113.4.86/C.292-C.297  April-December 1963, February 1980

Contents:
National Incomes Commission
Krebs's continued concern about Oxford salaries and in particular the difficulties in attracting first-rate staff to full-time university posts not carrying a college fellowship is reflected in his interest in the Commission's review of academic salaries.
Krebs was one of a number of Oxford scientists who submitted memoranda to the Commission.
The material is presented in a chronological sequence.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.292  1963

Contents:
April-May
Includes copy of memorandum submitted by C.D. Darlington, 'The consequences of the double standard of payment under the college system in Oxford'.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.293  1963

Contents:
June
Two drafts of the memorandum Krebs submitted to the Commission, 'Salaries of Oxford University Staff'.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.294  1963

Contents:
July-September
Includes Krebs's comments on the note submitted by the University Registry to the Commission.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.295  1963

Contents:
October
Includes copy of memorandum submitted by J.W.S. Pringle, 'Salaries of University Biologists', further material produced by Krebs commenting on the Registry's factual note on Oxford salaries and note by Krebs on undergraduate and postgraduate teaching in the biochemistry department.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.296  1963

Contents:
November-December
Includes copy of Krebs's second memorandum in the form circulated to other parties by the Commission.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.297  February 1980

Contents:
Note by Krebs commenting on the work of the Commission.

[no title or date]  CSAC 113.4.86/C.298-C.328


Related information: See also CSAC 113.4.86/A.195.

Administrative history:
In February 1964 the Hebdomadal Council appointed a committee chaired by the Provost of Worcester College (Lord Franks) to consider the recommendations and criticisms in the Robbins Report on Higher Education which particularly affected Oxford. The committee's terms of reference were wide-ranging, extending 'not only to the organisation and activity of the University but also to the teaching arrangements of the Colleges' (Report of Commission of Inquiry, I, p.17). The committee issued general and specific invitations to persons and organisations to submit written evidence which might help them in dealing with any of their terms of reference and sent out questionnaires on aspects of academic policy and university organisation. It was made clear that all written evidence apart from replies to questionnaires addressed to individuals would be made available to the public (Report, I, p.13).
Krebs was involved as a member of an ad hoc sub-committee in preparing the Heads of Science Department's response to the Commission's July questionnaire on teaching and research (CSAC 113.4.86/C.298, CSAC 113.4.86/C.299). He also prepared in October his own very extensive memorandum of written evidence on the organisation of science at Oxford (CSAC 113.4.86/C.302-CSAC 113.4.86/C.307). He was not able to submit this memorandum, however, because he was unwilling to have it made public. Instead, in November, he submitted a short memorandum which sought unsuccessfully to change the Commission's policy on the question of confidentiality (CSAC 113.4.86/C.308). It was not until the end of January 1965 that Krebs submitted a major memorandum to the Commission (CSAC 113.4.86/C.309) - a memorandum substantially different in character from that prepared in October 1964.
In 1966 the Commission issued a report of its findings with a large number of recommendations. In his autobiography Krebs expressed his disappointment that so very few had actually been implemented by the university (Rem. & Refl., pp.202-3).

Contents:
Franks Commission of Inquiry, 1964-68

[no title or date]  CSAC 113.4.86/C.298, C.299

Contents:
Heads of Science Departments Sub-committee on Franks Commission, 1964
In June the Commission of Inquiry sent a letter to the Chairman of the Committee of Heads of Science Departments (followed by a detailed questionnaire in July) requesting written evidence on various aspects of academic policy. At its meeting of 13 July the Committee of Heads of Science Departments appointed a sub-committee to draft a reply to the Commission's questionnaire and all heads were invited to send short replies to the Chairman for the sub-committee's consideration. Krebs was a member of the sub-committee.
The material presented here is a chronological sequence of committee papers including copies of the heads' replies.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.298  June-July 1964

Contents:
Includes copies of the replies and comments on the questionnaire by D.D. Woods, W. Hume-Rothery, R.C. Oldfield, R.E. Peierls, C.A. Coulson, and C.D. Darlington, and draft of Krebs's answers to Franks's questionnaire, misdated 15 July 1965.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.299  August-September 1964 and nd

Contents:
Includes comments on the questionnaire by J.W.S. Pringle and D.H. Wilkinson, summary of comments received and draft replies to the questionnaire.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.300  1964-66


Related information: See CSAC 113.4.86/C.308.

Contents:
Correspondence with the Franks Commission
Includes letter from Lord Franks, 8 December 1964, replying to Krebs's request that the Commission reconsider the rule that all their evidence should be public.
For the memorandum in which Krebs's request was set out

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.301  November and December 1964

Contents:
Correspondence with J.E. (later Lord) Vaizey and R.N.W. (later Lord) Blake re Oxford reform and the Franks Commission
The correspondence arose because of Krebs's comments (in his memorandum on confidentiality submitted to Franks in November) on articles by Vaizey and Blake in the Oxford Magazine and Oxford respectively.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.302  1964

Contents:
'Comments concerning the organisation of science at Oxford', October 1964.
'Complete' 60pp. typescript memorandum with ms. note by Krebs: 'Intended for Franks Committee [sic] but not accepted because of the confidentiality I asked for'.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.303  n.d

Contents:
'First draft' of section 16 of the preceding: 'Concepts to be clarified'.
At least part of this was written as early as 1962 for another purpose.

[no title or date]  CSAC 113.4.86/C.304, C.305

Contents:
'Final Draft'

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.304  1964

Contents:
Typescript draft with ms. additions and corrections of sections 1-13 of Krebs's October 1964 memorandum on the organisation of science at Oxford.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.305  n.d

Contents:
Typescript draft, with ms. additions and corrections of sections 15-23 of the memorandum.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.306, C.307  1964

Two folders.


Related information: (See CSAC 113.4.86/C.302.)

Contents:
'Early Incomplete draft'
Typescript draft of part of Krebs's memorandum with ms. corrections and additions.
This appears to be a revision of the 'complete' October 1964 draft and may have been undertaken because of the confidentiality question.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.308  1964

Contents:
'Memorandum submitted to the Commission of Inquiry by H.A. Krebs', November 1964.
3pp. typescript with covering letter.
Krebs explains why he feels unable to submit the major memorandum he has completed and asks the Commission to reconsider their decision not to accept confidential evidence.
Folder also includes various ms. and typescript drafts relating to the memorandum submitted.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.309  1965

Contents:
'Comments on the organisation and administration of a Science Department', 29 January 1965.
15pp. typescript and 2pp. appendix.
This is the major memorandum actually submitted to the Commission by Krebs. He describes it, in his first sentence, as 'written in response to an informal request from a member of the Commission'.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.310-C.312  1963-1964

Contents:
Miscellaneous ms. and typescript notes from a folder inscribed '1963-64. FRANKS'.
The material is presented in a chronological sequence as far as possible and divided into three folders for ease of reference.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.313-C.315  1963-1965


Related information: See the original folder preserved at CSAC 113.4.86/C.313.

Contents:
A sequence of dated ms. and typescript notes, January 1963-March 1965.
The material is divided into three folders for ease of reference.
Krebs may have put this material together in connection with the evidence he gave before the Commission in person.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.316-C.318  1964-1965

3 folders.

Contents:
Miscellaneous ms. and typescript notes and draft re Franks Commission. A few are dated in 1964 and 1965.

[no title or date]  CSAC 113.4.86/C.319, C.320

Contents:
Submissions to Franks Commission by others.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.319  1965

Contents:
Report of evidence submitted by Hebdomadal Council and General Board, June 1965.
52pp. duplicated typescript.
Folder also includes 1p. ms. note found with report of evidence.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.320  n.d

Contents:
Draft report to the Franks Commission from the postgraduate students of the Biochemistry Department.
Unidentified draft submission annotated by Krebs.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.321  1965

Contents:
Copies of supplementary numbers of Oxford University Gazette, 20 January and 12 May 1965, re Franks Commission.
There is marginal emphasis and underscoring by Krebs.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.322  1966

Contents:
A sequence of dated typescript and ms. notes commenting on the Franks report, June 1966-April 1967.
The report was published in May 1966.
Folder also includes 2pp. duplicated typescript statement, 16 June 1966, re attitude of Trinity College to the Franks report and initialled A.L.P.N [orrington] and 1p. duplicated typescript statement, 30 June 1966, on the 'General Board Comments on the Proposals of the Franks Commission', by J.W.S.P [ringle].

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.323  1967

Contents:
Brief exchange of correspondence and note of discussion on Oxford reform between Krebs and J.R. Maddox, February-March 1967.
Found with preceding material.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.324  1967-1968

Contents:
Hard-backed notebook. Unpaginated with many pages unused.
This notebook which was found with the Franks material is in the same format as those in which Krebs recorded his research at Berlin, Altona and Freiburg and may be the missing volume noted at CSAC 113.4.86/D.10. Pages have been torn from the front of the notebook.
Krebs used this notebook for jotting down his ideas on various aspects of Oxford reform which he may have intended to use for an article in Nature or the Oxford Magazine or a course of lectures. There are references to both the Robbins and Franks reports.
Dated entries run between 11 November 1967 and 7 February 1968.
Loose items have been removed and preserved in separate folders.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.325  1962-1967

Contents:
Krebs's ms. and typescript notes found in CSAC 113.4.86/C.324 above. Some of these are identified as notes for proposed lectures. There is also material on Schedule A Professors dating from 1962, and on 'Democracy' and the 'Effectiveness of Postgraduate Teaching' from November 1967.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.326  1967

Contents:
Soft-backed 'exercise book' found in CSAC 113.4.86/C.324 above.
Krebs used this notebook for jotting down his ideas on university government and academic leadership, July-September 1967. Pages have been torn from the book.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.327  n.d

Contents:
Newspaper cuttings found in CSAC 113.4.86/C.324 above.
Subjects include Oxford reform. democracy and the organisation of science.

Committees and Commissions of Inquiry, 1961-68, 1980  CSAC 113.4.86/C.328  n.d

Contents:
Miscellaneous press-cuttings found with Franks material.

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.329-C.334  [n.d.]

Contents:
Drafts of articles by Krebs and others for the Oxford Magazine, and related correspondence.
For other material re Oxford Magazine see CSAC 113.4.86/C.28, CSAC 113.4.86/C.228 and CSAC 113.4.86/C.267.

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.329  1960

Contents:
Papers

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.330  1961

Contents:
'The Flexibility of Salaries'
Drafts of Krebs's article published 1 June.

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.331  1961

Contents:
'Oxford life as seen by a University Demonstrator appointed from outside'
Drafts of article by W. Bartley, later Professor of Biochemistry at Sheffield, published 8 June.
The article was heavily revised by Krebs and appears anonymously.

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.332  1961

Contents:
'The salaries of demonstrators'
Correspondence and draft of article, published October.

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.333  1962, 1964

Contents:
1964 material is a letter to the editor submitting a letter for publication on college taxation.

Publications, 1960-62, 1964, 1967  CSAC 113.4.86/C.334  1967

Contents:
Material re Krebs's letter on graduate supervision fees published 17 February, including printed version of letter.

GENERAL UNIVERSITY CORRESPONDENCE  CSAC 113.4.86/C.335-C.389  [n.d.]

Contents:
C.335-C.361 Central administration
C.362-C.372 Electoral Boards
C.373-C.389 Libraries, departments, colleges and societies.

Central administration  CSAC 113.4.86/C.335-C.361  [n.d.]

Contents:
A chronological sequence of correspondence and papers with officers of the University, academic colleagues, etc. re the Biochemistry Department, and the general affairs of the university, kept together by Krebs as his 'University files'.

Central administration  CSAC 113.4.86/C.335  1954

Contents:
Includes material re the qualifying examination in German for undergraduates offering Biochemistry in the Final Honour School of Natural Science.

Central administration  CSAC 113.4.86/C.336  1955

Contents:
Includes material re Gotch Memorial Prize, General Board grant, bench fees and the provision of scientific equipment for the university (electron microscope) and department (recording spectrometer).

Central administration  CSAC 113.4.86/C.337  1956

Contents:
Brief correspondence re Japanese research student.

Central administration  CSAC 113.4.86/C.338  1957


Related information: See CSAC 113.4.86/C.190-CSAC 113.4.86/C.201.

Contents:
Includes material re higher degrees, including A.G. Ogston's comments on a memorandum of C.D. Darlington about the training of students for higher degrees and re a cooperative effort of science professors to raise money for the university. With a memorandum by Krebs on university finance.
For the cooperative effort to raise money

Central administration  CSAC 113.4.86/C.339  1958

Contents:
Includes material re removal expenses, support for Krebs's research from the United States Public Health Service and radiation hazards.
The question of removal expenses led Krebs to prepare a memorandum on the financial situation of the higher income groups in the university. One of the two copies in this folder has the marginal comments of E.R.H. Jones.

Central administration  CSAC 113.4.86/C.340  February, May 1959

Contents:
Includes material re the future of Astronomy in the university and the staffing requirements of the Biochemistry Department.

Central administration  CSAC 113.4.86/C.341  June 1959

Contents:
Agenda and committee papers for Board of the Faculty of Biological Sciences meeting, 9 June.

Central administration  CSAC 113.4.86/C.342  June-July, December 1959

Contents:
Includes material re the University Demonstrator scale and the relation between salaries in Oxford and in other universities. There is a copy of a memorandum by Krebs on the salaries of university demonstrators.

Central administration  CSAC 113.4.86/C.343  January 1960

Contents:
Includes material re Biochemistry Department staffing and expenditure and salaries in Oxford generally.

Central administration  CSAC 113.4.86/C.344  February-March 1960

Contents:
Includes material re salaries and staffing in the department and the university generally.

Central administration  CSAC 113.4.86/C.345  May-June, October 1960

Contents:
Includes material re academic salaries, Biochemistry Department appointment and technicians in the department.

Central administration  CSAC 113.4.86/C.346  1961


Related information: See also CSAC 113.4.86/C.94-CSAC 113.4.86/C.96.

Contents:
Exchange of correspondence re Laboratory of Human Nutrition.

Central administration  CSAC 113.4.86/C.347  February-May 1962

Contents:
Includes Krebs's offer of resignation from the Hebdomadal Council and his note of the future space requirements of the Biochemistry Department in response to a request from the University Surveyor.

Central administration  CSAC 113.4.86/C.348  June 1962

Contents:
Includes note on college teaching and memorandum for the General Board on the lecturing obligations of readers, lecturers and demonstrators. Amongst the material associated with the memorandum are a heavily corrected draft, the report of the committee appointed (by the Board of the Faculty of Biological Sciences) to consider the duties of readers, lecturers and university demonstrators, 11 June, with Krebs's ms. comments, and a note by Krebs on the functions of professors and readers dated 15 July 1961.

Central administration  CSAC 113.4.86/C.349  July, October-November 1962

Contents:
Includes material re Council papers, academic salaries, departmental estimates and animal house accommodation.

Central administration  CSAC 113.4.86/C.350  January-May 1963

Contents:
Includes Krebs's memorandum on the payment of extra fees to full-time university teaching staff.

Central administration  CSAC 113.4.86/C.351  November-December 1963

Contents:
Includes material re payment of fees to lecturers teaching in a department other than their own.

Central administration  CSAC 113.4.86/C.352  January-June 1964

Contents:
Includes material re salaries, staffing and appointments.

Central administration  CSAC 113.4.86/C.353  July-December 1964

Contents:
Includes material re the transfer of financial responsibilities for research projects from research councils to the university and the Schedule A Professorship of Chemical Microbiology.
In his letter to the Registrar of 5 October, Krebs raised the question whether a take-over of the Cell Metabolism Research Unit should be considered for 1967 when he was due to retire.

Central administration  CSAC 113.4.86/C.354  1965

Contents:
Correspondence re arrangements for the resignation of a member of the department and the transfer to his new university of equipment bought from outside grants.

Central administration  CSAC 113.4.86/C.355  1966

Contents:
Includes memorandum on future developments in the Biochemistry Department.

Central administration  CSAC 113.4.86/C.356  1967

Contents:
Correspondence re inclusion in Krebs's last annual report of a special section on the transfer of responsibilities to his successor, and a draft of the special section.
Folder also includes a ms. note by Krebs (1979) which relates to his 1967 Annual Report.

Central administration  CSAC 113.4.86/C.357  1969


Related information: See CSAC 113.4.86/C.368-CSAC 113.4.86/C.372.

Contents:
Draft letter to the Chairman of the General Board re current practice of selecting candidates for appointments to readerships, with draft paper, dated 4 December 1967, on the Biology Readership Committee.
Krebs's letter of resignation from the Electorship of the Sibthorpian Professorship of Rural Economy and of the Directorship of the Nuffield Institute.
For Biology Readership Committee

Central administration  CSAC 113.4.86/C.358  1970

Contents:
Includes 12pp. typescript letter from Krebs to the Secretary of the General Board on the corruption 'in a subtle way' of the higher academic administration of the university. Krebs was encouraged to put his views on paper by the question of the use of fees by postgraduate students who received all their instruction in his laboratory and contended that the university administration was 'grossly biased towards channelling moneys to Colleges and College Fellows'.

Central administration  CSAC 113.4.86/C.359  1977, 1979

Contents:
1977 material is a letter re financial arrangements for the Metabolic Research Laboratory.
1979 material includes correspondence re a proposed 'German House' in Oxford and 2pp. typescript note of Krebs's discussions with the Chairman of the General Board on fees for postgraduate supervision.

Central administration  CSAC 113.4.86/C.360  1980

Contents:
Correspondence re the finances of the Metabolic Research Laboratory in general and the use of fees paid by postgraduate students in particular.

Central administration  CSAC 113.4.86/C.361  1981

Contents:
Continuing correspondence re financial arrangements for the Metabolic Research Laboratory and fees for graduate supervision.

Electoral Boards  CSAC 113.4.86/C.362-C.372  [n.d.]

[no title or date]  CSAC 113.4.86/C.362-C.367

Contents:
Board of Electors to the Waynflete Professorship of Physiology, 1959-60, 1967.
The material, which consists of correspondence, committee papers and Krebs's typescript notes on the merits of the candidates, relates to elections in 1959-60 and 1967.

[no title or date]  CSAC 113.4.86/C.362-C.364

Contents:
1959-60

Electoral Boards  CSAC 113.4.86/C.362  September-November 1959

Contents:
Papers

Electoral Boards  CSAC 113.4.86/C.363  December 1959

Contents:
Papers

Electoral Boards  CSAC 113.4.86/C.364  January 1960 and nd

Contents:
Papers

[no title or date]  CSAC 113.4.86/C.365-C.367

Contents:
1967

Electoral Boards  CSAC 113.4.86/C.365  March-May 1967

Contents:
Papers

Electoral Boards  CSAC 113.4.86/C.366  June

Contents:
Papers

Electoral Boards  CSAC 113.4.86/C.367  July, September and nd

Contents:
Papers

Board of Faculty of Biological Sciences, Ad Hoc Committee on Readerships, 1965, 1967-69.  CSAC 113.4.86/C.368-C.372  [n.d.]

Electoral Boards  CSAC 113.4.86/C.368  1965

Contents:
Details of applicant.

Electoral Boards  CSAC 113.4.86/C.369, C.370  1967

2 folders.

Contents:
Agenda of meeting and details of applicants.

Electoral Boards  CSAC 113.4.86/C.371, C.372  1968-69

2 folders.

Contents:
Correspondence, agenda, details of applicants and report of committee.

Libraries, departments, colleges and societies  CSAC 113.4.86/C.373-C.389  [n.d.]

Libraries, departments, colleges and societies  CSAC 113.4.86/C.373  1955-1964

Contents:
Bodleian Library/Radcliffe Science Library, 1955, 1958, 1963-64

Libraries, departments, colleges and societies  CSAC 113.4.86/C.374  1960-1971

Contents:
Nuffield Department of Clinical Biochemistry, 1960-61, 1971
1960-61 material relates to equipment grant for new laboratory.
1971 material relates to appointments.

Libraries, departments, colleges and societies  CSAC 113.4.86/C.375  1965

Contents:
University Laboratory of Physiology, 1965

Libraries, departments, colleges and societies  CSAC 113.4.86/C.376  1955-1979

Contents:
Miscellaneous invitations for Krebs to attend lectures and seminars in other Oxford departments, 1955, 1967-68, 1972, 1978-79.
1967-68 material relates to a course in autoradiography techniques and includes brief related scientific correspondence and notes.

Libraries, departments, colleges and societies  CSAC 113.4.86/C.377  1958-1978

Contents:
Keble College, 1970
Centenary Appeal.
Trinity College, 1958-59, 1968, 1970-71, 1978
Ms. notes on Fellows by D.D. Woods, n.d.
Miscellaneous correspondence with Fellows and Presidents (in alphabetical order).

Libraries, departments, colleges and societies  CSAC 113.4.86/C.378  1961-1980

Contents:
St. Catherine's College, various dates 1961-78, 1980
1961-63 material is minutes of the committee on St. Catherine's College of which Krebs was a member.

Libraries, departments, colleges and societies  CSAC 113.4.86/C.379  1971, 1974

Contents:
Ashmolean Club, 1971, 1974
Invitations to meetings and list of members (1971)

[no title or date]  CSAC 113.4.86/C.380-C.389

Contents:
Secure Retirement Association Limited, 1970-71
The Association was founded to provide in Oxford, 'apartments and amenities' for retired professional men and women. The prime mover was Dr. W. Ritchie Russell and Krebs was involved from an early stage in the planning.
The material, correspondence, committee papers, etc. is presented in a chronological sequence.

Libraries, departments, colleges and societies  CSAC 113.4.86/C.380  July, October 1970

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.381  November-December 1970

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.382  January-February 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.383  March 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.384  April 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.385  May 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.386  June 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.387  July 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.388  August-September 1971

Contents:
Papers

Libraries, departments, colleges and societies  CSAC 113.4.86/C.389  October, November 1971, and nd

Contents:
Papers

SECTION D RESEARCH  CSAC 113.4.86/D.1 - D.569  [n.d.]

Contents:
D.1 -D.45 LABORATORY NOTEBOOKS
With an introductory note
D.46 -D.100 INDEXED NOTES AND MEMORANDA
With an introductory note
D.101-D.514 RESEARCH PROJECTS
With an introductory note and a list of contents
D.515-D.548 MISCELLANEOUS NOTES
D.549-D.569 BIBLIOGRAPHICAL REFERENCES
This Section is confined to Krebs's scientific research, essentially on various aspects of metabolism. Section E deals with his work on more general science-related topics, and includes memoranda, notes, research ideas and annotated background material of similar type. For additional material on Krebs's wartime research, especially on nutrition, see Section B.
As with the various engagement and personal diaries and jotters in Section A, so here the sub-divisions above correspond more to convenience and/or chronology than to any essential difference of content.
The most straightforward category is the sequence of Laboratory Notebooks (CSAC 113.4.86/D.1-CSAC 113.4.86/D.45). These are hardbacked notebooks of a traditional kind in which Krebs and his collaborators recorded data and experimental results. Even here, there are problems of dating, and complications arising from Krebs's habit of intercalating loose pages of notes, correspondence and other more or less related material (see the introductory note to CSAC 113.4.86/D.1-CSAC 113.4.86/D.45), a practice which threatened to reduce the original notebook to an over-strained outer shell.
Later, and certainly after his move to Oxford, Krebs began to keep his manuscript notes on loose pages or on dictated cassettes which were intended to be - and often were - typed up on standard octavo paper, dated, and kept with related correspondence, bibliographical and printed matter, records of discussions and information received, data and results, drafts, and all other miscellaneous material accumulated for research in progress. These are the basis of all the other categories in Section D, and, mutatis mutandis, Section E.
The Indexed Notes and Memoranda (CSAC 113.4.86/D.46-CSAC 113.4.86/D.100) were received in ring-back or clamped folders and binders, made up to incorporate research material, by Krebs or under his direction. It is possible that the task of making up the folders was often overtaken by pressure of active research, or that they were cannibalised and broken up to allow Krebs to remove material for use in research, writings or lectures. At all events, some incomplete bundles, part-indexed or with items missing, were received in plastic envelopes (see the introductory note to D.46-D.100).
The material designated as Research Projects (CSAC 113.4.86/D.101-CSAC 113.4.86/D.514) was received in boxes of various sizes and format whose only common denominator was that they were too small for the job. Some of the boxes, and of the folders within them, had descriptive titles by Krebs, and these have been retained and quoted in inverted commas in the relative entries, though their overflowing contents have often been redistributed in smaller units for ease of handling and reference. There is a significant difference here from the 'Indexed Notes and Memoranda' in the inclusion of a higher proportion of laboratory results and data, instructions for experiments and discussions with collaborators such as L.V. Eggleston, R. Hems, M. Stubbs and many visiting scientists, and extensive drafts for lectures and publications. The study of the latter, incidentally, makes clear the way the research notes were used as quarries for published work, being discussed, re-drafted, superseded and eventually incorporated over a considerable timespan. There is also a much larger component of background material, some annotated by Krebs. The presentation adopted is chronological from the first date of the records found under the relevant topic heading (see the introductory note).
The Miscellaneous Notes (CSAC 113.4.86/D.515-CSAC 113.4.86/D.548), though no different in essence from the 'Indexed Notes', were either received in very crammed folders simply inscribed 'Memos', or found scattered elsewhere in the collection. Some quite clearly refer to specific research topics (mitochondria, isolated liver cells, etc.) while others are more general and less easy to assign. Some are undated and some are illegible. In many cases, it would seem largely a matter of chance that they had remained undistributed among the indexed folders or the research boxes.
ADDENDUM
Attention is drawn to CSAC 113.4.86/D.9A the laboratory notebook of K Henseleit, August 1931-January 1933, covering the period of collaborative research on the ornithine cycle, which complements Krebs's own notebooks at CSAC 113.4.86/D.9, CSAC 113.4.86/D.10.

LABORATORY NOTEBOOKS  CSAC 113.4.86/D.1 - D.45  [n.d.]

Contents:
These are all hardbacked notebooks presented in a chronological sequence, 1926 - 48, 1962 - 64, 1970 - 71. They cover Krebs's research at Berlin, Altona and Freiburg (in a set of standard format CSAC 113.4.86/D.1 - CSAC 113.4.86/D.10 (part)), Cambridge (CSAC 113.4.86/D.10 (part) - CSAC 113.4.86/D.13), Sheffield (CSAC 113.4.86/D.14 - CSAC 113.4.86/D.38) and Oxford (CSAC 113.4.86/D.39 - CSAC 113.4.86/D.45; a few books only, as Krebs had then adopted a different method of note-taking). A few books are by collaborators or assistants. With these few exceptions, all the books, in German and English, are in Krebs's hand, often with re-workings and corrections, and many with indexes at front, rear or both. Several have letters or information pasted in and most have loose pages of notes, diagrams, correspondence, etc. intercalated at various points; the more significant of these items have been removed for safety to separate folders adjoining the original book. The pages of most are numbered and this, with Krebs's indexes, simplifies the location of particular experiments or results. The books are thus a rich source for the progress of Krebs's research, though it should also be stressed that the diaries and 'jotters' in Section A were very frequently used by Krebs, especially in later life, to record his thoughts on technical as well as general and personal matters.
Several of the books were received with numbered labels stuck on to the front cover, it is not known when or by whom. These labels, sometimes incorrect and in any case note extending to the full range of the material, have been ignored in the chronological presentation here adopted. Krebs's own contemporary numbered sequence for his Sheffield notebooks (Books 2 - 7 only) has, however, been preserved at CSAC 113.4.86/D.14 - CSAC 113.4.86/D.21.
Books CSAC 113.4.86/D.1 - CSAC 113.4.86/D.12 are all in German.

Laboratory Notebooks  CSAC 113.4.86/D.1  1926


Related information: See CSAC 113.4.86/D.4 for research related to above paper.

Contents:
Notebook inscribed 'Krebs' on front cover. Pages numbered 1-192, with a thumb-index at rear which incorporates a few additional unnumbered pages. There is a selective list of contents on the last page (W-Z) of this thumb-index.
The work is mainly on the oxidation of fructose. Experiments run 7 May-28 October 1926. There are a few intercalated loose pages, and a copy of Krebs's paper on carbon monoxide and haem catalysis (Bibliog. 18. Rem. & Refl. p.37). Includes notes and corrections in ink and pencil, charts and diagrams pasted in (and some loose), etc.

Laboratory Notebooks  CSAC 113.4.86/D.2  1926-1927

Contents:
Notebook inscribed 'Dr. Krebs' on front cover. Pages numbered 1-192, with some intercalated loose pages of tabulated results.
The work is mainly on serum, 18 November 1926-2 March 1927. Includes experimental results, in ink and pencil, some marked in red pencil for use in publication. Also notes on the literature.

Laboratory Notebooks  CSAC 113.4.86/D.3  1927

Contents:
Notebook inscribed 'Dr. Krebs' on front cover. Pages numbered 1-384, with several intercalated loose pages at various points.
Continuing work on serum, 3 March-21 November 1927. Includes experimental notes, tabulated results in ink and pencil, some marked in red pencil for publication. Perhaps related to Bibliog. 14, and also to work on copper in blood (Bibliog. 15, 17).
Intercalated between pp.100 (13 April) and 101 (20 April) is a 1p. ms. note, 17 April [Easter Sunday] of ideas on blood, with a ms. 'Note added 31.12.70' discussing earlier research.

Laboratory Notebooks  CSAC 113.4.86/D.4  1927-1928

Contents:
Notebook inscribed 'Krebs' on front cover, and with name and address of Kaiser Wilhelm Institute of Biology inside front cover. Pages numbered 1-384, with lists of contents at front and rear.
The work is mainly on oxidation and on trace elements, 12 December 1927-19 June 1928. Experimental results, many diagrams pasted in, markings in red pencil for publication, several referring to the paper on haem catalysis (Bibliog. 18, see also CSAC 113.4.86/D.1).

Laboratory Notebooks  CSAC 113.4.86/D.5  1928-1929

Contents:
Notebook inscribed 'Krebs' on front cover. Pages numbered 1-288, with a few loose pages, and a list of contents at rear.
Material runs 22 June 1928-19 January 1929. Experimental data, tabulated results, diagrams pasted in, work in ink and pencil.
N.B. This book has been incorrectly labelled '6' though the dates of the material follow in sequence from CSAC 113.4.86/D.4.

Laboratory Notebooks  CSAC 113.4.86/D.6  1929

Contents:
Notebook inscribed 'Krebs' on front cover. Pages numbered 1-288 with a few loose pages.
Continuing work on cysteine and other enzymes, 21 January 1929(Wrongly indicated 1928 for January entries.)-26 November 1929. Experiments, results, tabulated data, diagrams pasted in.
N.B. This book has been incorrectly labelled '5' though the dates of the material follow in sequence from CSAC 113.4.86/D.5.

Laboratory Notebooks  CSAC 113.4.86/D.7  1929-1930

Contents:
Notebook inscribed 'Krebs' on front cover. Pages numbered 1-288, with a few loose pages. There is a selective list of contents on pp.279-280.
Work on various catalysing agents, 29 November 1929-17 August 1930. On p.165 is a note 'Ende in Dahlem' and p.170 is headed 'Altona'. Krebs was given notice to leave Warburg's laboratory by 31 March 1930, and accepted a post with Professor Leo Lichtwitz at the Municipal Hospital of Altona, beginning work there on 1 May 1930 (Rem. & Refl. pp.40-43).

Laboratory Notebooks  CSAC 113.4.86/D.8  1930-1931

Contents:
Notebook inscribed 'Krebs' and 'Protokolle 1.9.30 bis 1.4.31' on front cover. Pages numbered 1-480. There is a list of contents on an unnumbered page at front, and summary of ideas and points of interest at rear of book. Several loose pages (mainly patients' records) are inside front cover, and there is also an offprint of Krebs's paper on proteolytic enzymes (Bibliog. 27. Rem. & Refl. p.44).
Work mainly on protein catalysis, 3 September 1930-25 March 1931. Experiments, calculations, tabulated results, notes on the literature, diagrams pasted in, several pages marked in red pencil for publication.

Laboratory Notebooks  CSAC 113.4.86/D.9A  1931-1932

Contents:
Notebook of K. Henseleit
Henseleit was a medical research student at Freiburg and Krebs's collaborator on the research and publications on the ornithine cycle (Rem. & Refl., p.47).
The material is in the form of a photocopy made by Krebs from the original notebook in the possession of Henseleit's widow and given by him to Professor F.L Holmes who has now (March 1986) made it available for the collection.
The original was a hardback octavo identical to Krebs's notebooks at D.9, D.10. The content is also similar, including notes on the literature, tabulated observations and results. Occasionally Krebs's notebooks have a reference to 'Henseleit' and the ensemble is an interesting example of collaborative research.
The photocopy as received is in two parts:
Part I August 5, 1931 - January 22, 1932, pp.1-177.
Part II January 23, 1932 - January 6, 1933, pp.178-380 + 3pp. list of contents.

Laboratory Notebooks  CSAC 113.4.86/D.9  1932

Contents:
Notebook inscribed 'Krebs' and 'Protokolle' on front cover. Pages numbered 1-576, with a few loose pages and a list of contents at rear of book.
This, together with part of CSAC 113.4.86/D.10 below, covers Krebs's period as 'Assistant' in the Department of Medicine at Freiburg University, at the invitation of S. Thannhauser (Professor of Medicine). He took up his post at Freiburg on 1 April 1931 and remained there until he left Germany in June 1933. It was during this period that he made his first major research discovery, of the ornithine cycle of urea synthesis (Rem. & Refl. pp.43-60).
Work mainly on urea synthesis, 12 May 1931-2 November 1932.

Laboratory Notebooks  CSAC 113.4.86/D.10  1932-1934, 1982


Related information: See CSAC 113.4.86/C.324.

Contents:
Notebook inscribed 'H.A. Krebs' and '1932-1934' on front cover. Pages numbered 1-576, with a few loose pages. There are several lists of contents, on pp.260, 270 and at rear.
This is a particularly interesting volume, beginning with the continuation of work on the ornithine cycle, many pages being marked in red pencil for publication (pp.1-241). Pasted into p.244 is Krebs's hotel bill at the Black Forest resort of St. Peter and (intercalated) a later bill when he revisited the same pension with his family in 1972. P.260 is headed 'Cambridge', the first entry being dated 4 July 1933 (Rem. & Refl. pp.62-63, 86-87).
Entries run 4 November 1932-11 April 1933 (from Freiburg), 4 July 1933-24 March 1934 (from Cambridge). All the entries are in German.
N.B. At rear of book is a note by Lady Krebs 'Vol.II missing', dated 29 July 1982.

Laboratory Notebooks  CSAC 113.4.86/D.11  1933-1935

Contents:
'Minute Book' (in poor condition). Pages numbered 1-300, with detailed list of contents pp.286-289.
Work on amino acids, synthesis of glutamine. Experiments, tabulated results, notes on the literature, in ink with many annotations and re-workings in red ink, perhaps for publication. First entry is 9 April 1933 (in error for 1934)-14 January 1935.
All in German except for an account of 'Unit and determination' on pp.294-5.

Laboratory Notebooks  CSAC 113.4.86/D.12  1935

Contents:
'Minute Book' (in poor condition). Pages numbered in red pencil 1-266 but work continues to end of book.
Continuing work mainly on animo acids in mammalian tissues, 14 January-3October 1935. Experiments, diagrams pasted in, etc. in black and red ink as in CSAC 113.4.86/D.11 above. All in German except for a few notes mainly at end of book (see entry for 2 October on work with D.D. Woods).
There are a few loose pages of notes and calculations inside and at rear of book. More significant letters and items found loose in the book have been removed and now appear at CSAC 113.4.86/D.13.
In addition, several items of interest are pasted into the book at various points. On p.25 is a notice of a Biochemical Society meeting, 15 February 1935, at which Krebs communicated two papers on 'Deamination of amino acids in mammalian tissues' and 'Synthesis of glutamine in mammalian tissues'. On p.199 is letter from Ella Sachs Plotz Foundation, 5 June 1935, awarding Krebs £150 for purchase of apparatus. On pp.230, 231 is correspondence, July 1935, re Krebs's application for post as Lecturer in Pharmacology, Sheffield, with letter from E.J. Wayne (Rem. & Refl. pp.93-94, see also CSAC 113.4.86/D.13). Material at rear of book includes notice of a Biochemical Society meeting, 15 November 1935, at which Krebs presented a collaborative paper with N.L. Edson and A. Model on 'The synthesis of uric acid in birds'. (Bibliog. 52, 53, 57.)

Laboratory Notebooks  CSAC 113.4.86/D.13  1935-1936

Contents:
Correspondence and papers originally found loose in CSAC 113.4.86/D.12. Includes correspondence with Cambridge University re Krebs's employment of a personal assistant, further correspondence with E.J. Wayne on Krebs's appointment at Sheffield (October 1935), correspondence with colleagues on research and publications, 1935-36.
Also included are press-cuttings on the difficulties of learning the English language (Rem. & Refl. p.89).

Laboratory Notebooks  CSAC 113.4.86/D.14  1935-1936

Contents:
Notebook inscribed 'Book 2' inside front cover. There is no 'Book 1' of this sequence surviving. Pages numbered 1-233 with detailed list of contents on pp.232-33. Pages 162-63 are left blank, with a note 'Journey to Palestine' 21 March-21 April 1936 (Rem. & Refl. pp.90-91)
Work on aspects of metabolism, 22 October 1935-8 June 1936. Experiments, results, notes on the literature, in ink and pencil, with several corrections and re-workings in red ink.

Laboratory Notebooks  CSAC 113.4.86/D.15  1936

Contents:
Notebook inscribed 'H.A. Krebs', 'Book 3' inside front cover. Pages numbered 1-232 with list of contents on pp.230-232 and a few loose pages.
Entries run 8 June-30 September 1936, covering experiments, tabulated results, comments, notes on the literature, etc. in ink and pencil, with several corrections and re-workings in red ink.
Pasted into pp.162, 163 are letters from colleagues forwarding specimens.

Laboratory Notebooks  CSAC 113.4.86/D.16  1936-1937

Contents:
Notebook inscribed 'H.A. Krebs. The University Sheffield' and 'Book 4' inside front cover. Pages numbered 0-226 with detailed list of contents on pp.224-25 and some loose pages and items pasted in.
Entries run 2 October 1936-8 March 1937, covering experiments, tabulated results, diagrams pasted in, many annotations and re-workings in red ink, several pages annotated in red pencil for paper or publication.
On p.32 is pasted notice of a Biochemical Society meeting on 17 October 1936 at which Krebs gave a paper on 'The oxidation breakdown of carbohydrates'; between pp.96 and 97 is a notice of a Chemical Society meeting on 26 November 1936 at which Krebs spoke on 'The biological breakdown of carbohydrates'.

Laboratory Notebooks  CSAC 113.4.86/D.17  1937

Contents:
Notebook inscribed 'H.A. Krebs. The University Sheffield' and 'Book 5' inside front cover. Pages numbered 1-232, with list of contents on inside back cover and some loose pages and items pasted in. There is a cumulative 'Contents of last 3 books with reference to Coli' on pp.224-25
Entries run 20 January-23 October 1937, covering experiments, tabulated results, charts and diagrams pasted in, many annotations and re-workings in red ink.
On p.42 and p.191 are pasted acknowledgements of papers submitted for publication in Biochem J.; on p.154 is pasted an acknowledgement of a paper submitted for publication in Enzymologia (Bibliog. 62). This was the crucial paper by Krebs and W.A. Johnson 'The role of citric acid in intermediate metabolism in animal tissue', offered to Enzymologia after its notorious rejection by Nature, never forgotten by Krebs (Rem. & Refl. pp.98-99).

Laboratory Notebooks  CSAC 113.4.86/D.18  1937-1938

Contents:
Notebook inscribed 'H.A. Krebs' and 'Book 6' inside front cover. Pages numbered 1-228, with list of contents on p.228 and dated list of calibrations on inside back cover. Some loose pages and items pasted in. Additional correspondence and items originally kept loose in book have been removed and now appear at CSAC 113.4.86/D.19.
Entries run 28 September 1937-11 July 1938 and include some of the definitive work on the citric acid cycle. Experiments, tabulated results, many annotations and re-workings in red ink.
On p.93 is pasted a notice of a Chemical Society meeting on 25 January 1938 at which Krebs spoke on 'The biochemical lesions in Vitamin B1 deficiency'.

Laboratory Notebooks  CSAC 113.4.86/D.19  1937-1938

Contents:
Correspondence and papers originally found loose in CSAC 113.4.86/D.18. Includes notice of a Biochemical Society meeting on 9 October 1937 at which Krebs gave a collaborative paper with W.A. Johnson on 'Citric acid as an intermediate metabolite in the oxidative breakdown of carbohydrates'. Correspondence with colleagues and with firms, on metabolism research, 1938

Laboratory Notebooks  CSAC 113.4.86/D.20  1938-1939

Contents:
Notebook inscribed 'Book 7' inside front cover, on which also appears address of Å. and M. Örström, co-authors of three papers with Krebs in 1939 (Bibliog. 72, 73, 74). Pages numbered 1-314, with several lists of contents to particular series of experiments on pp.40-41, 312 and inside back cover. There are several loose pages and items pasted in. Additional correspondence and items kept loose in book have been removed and now appear at CSAC 113.4.86/D.21.
Entries run 20 July 1938-30 March 1939, p.34 being left blank and headed 'Summer Holiday Congress Zürich' (Rem. & Refl. p.102). Experiments, charts and diagrams pasted in, summaries of results, notes on the literature, etc., many with annotations and re-workings in red ink.
On p.110 is pasted a note on results (in German), no author or date, but almost certainly from Å. Örström; on p.143 is pasted a letter from Örström, 5 January 1939; on p.145 is pasted a letter on analysis of results, 16 January 1939; on p.147 is pasted a notice of a Biochemical Society meeting on 13 January 1939 (at Leeds) at which Krebs spoke on 'Intermediary Metabolism of Proline' and introduced other papers by his collaborators; on p.244 is pasted acknowledgement of four papers submitted for publication in Biochem. J., 1 May 1939; on p.267 is pasted an acknowledgement of paper submitted for publication in Enzymologia (Bibliog. 77).

Laboratory Notebooks  CSAC 113.4.86/D.21  n.d

Contents:
Correspondence and papers originally found loose in CSAC 113.4.86/D.20. Includes letter from L. Farkas (ref. p.71), letters from colleagues, results and notes.
N.B. This marks the end of Krebs's own sequence of numbered notebooks 2-7 (no.1 is missing).

Laboratory Notebooks  CSAC 113.4.86/D.22  1936-1938

Contents:
Notebook similar in format to the preceding sequence, but kept in other hands by collaborators or assistants. There are a few notes by Krebs, e.g. dated 16 March 1937. Pages not numbered; some loose pages intercalated and at rear of book.
Entries run 25 July 1936-16 March 1937, and 2 March-2 May 1938.

Laboratory Notebooks  CSAC 113.4.86/D.23  1937-1938

Contents:
Red notebook inscribed 'H.A. Krebs. The University, Sheffield' inside front cover. This is Krebs's own notebook but does not form part of the numbered sequence with which it overlaps in date.
Pages not numbered; there is a list of contents on inside back covers. Some loose pages of notes, and a letter on vitamin B1 results, at rear of book.
Entries run 25 January 1937-8 March 1938. Experiments, charts and diagrams pasted in, many annotations and re-workings in red ink. Includes work on insulin, vitamin B1, citrate, etc.

Laboratory Notebooks  CSAC 113.4.86/D.24  1938

Contents:
Black soft-cover notebook, 6-20 April 1938.
Few pages used, mainly on depancreatised specimens. A few notes at rear of book, not all in Krebs's hand.

Laboratory Notebooks  CSAC 113.4.86/D.25  1938

Contents:
Black soft-cover notebook, small format, labelled on cover 'Note Book 1938. Amino Acid Determinations with Chloramine T'.
Earliest entry 31 August 1938. Entries 11-28 October are not in Krebs's hand but many have annotations by him.
A few notes on last page of book.

Laboratory Notebooks  CSAC 113.4.86/D.26  1939-1940

Contents:
Hardbacked notebook, pages numbered 1-312 with 'Index and Summary' on p.311 and index of relevant experiments in earlier notebooks on p.4. There are several loose pages of notes and calculations, and some items pasted in. Additional correspondence and items originally kept loose in book have been removed and now appear at CSAC 113.4.86/D.27.
Entries run 17 July 1939-26 April 1940; much of the work is on pigeon breast muscle. Acknowledgement for publication of Bibliog. 81, 82 is pasted in at p.165, and of Bibliog. 83 at p.213.

Laboratory Notebooks  CSAC 113.4.86/D.27  1940

Contents:
Correspondence and papers originally found loose in CSAC 113.4.86/D.26. Many are notices of meetings and publications (including meeting of Biochemical Society at Sheffield, 17 February 1940, organised by Krebs), letter from B. Mendel and telegram from H. Mcllwain about his move to Sheffield.

Laboratory Notebooks  CSAC 113.4.86/D.28  1940


Related information: See CSAC 113.4.86/D.29 below.

Contents:
Hardbacked notebook, relating to work on risks of exposure to fluorides in industry, carried out on behalf of the Home Office (Rem. & Refl. p.124).
Both ends of book used. Entries run 23 November 1939-1 February 1940 (few pages used).

Laboratory Notebooks  CSAC 113.4.86/D.29  n.d

Contents:
Loose pages of records on subjects examined, tabulation of data, originally kept in CSAC 113.4.86/D.28 above. Also included here is a 1p. note on citric acid synthesis.

Laboratory Notebooks  CSAC 113.4.86/D.30  1940-1941

Contents:
Hardbacked notebook, pages numbered 1-232, with list of contents and note of spending from Rockefeller grant on inside back cover, list of experiments to be done on propionic acid on p.230. Several loose pages intercalated, and items pasted in.
Entries run 6 June 1940-28 January 1941. Experiments, tabulated results, references, notes on the literature, etc., with many annotations and re-workings in red ink.
Pasted on to p.31 is notice of a 'holiday school of Biochemistry' at which Krebs was to speak, arranged for July 1940, and a letter from F.C. Happold cancelling it; intercalated on pp.106-07 are acknowledgements of two papers submitted to Biochem. J. (Bibliog. 86, 88); pasted on to pp.119, 187 are notices of Biochemical Society meeting on 5 October and 7 December 1940, at which Krebs gave papers; pasted on to p.134 is correspondence on propionic acid culture.

Laboratory Notebooks  CSAC 113.4.86/D.31  1941-1943

Contents:
Hardback notebook, pages numbered (on recto only) 1-115. There is a brief summary of contents on inside back cover and summaries of work on staphylococcus and on propionic acid bacterium on pp.35 (verso) and 37. A few loose pages of notes. More extensive notes and other items originally left at front and rear of book have been removed and now appear at CSAC 113.4.86/D.32.
Entries run 27 January 1941-4 August 1942. Experiments, tabulated results, references, notes on the literature, in ink and pencil, with annotations and re-workings in red ink and a note on p.90 verso of material used in paper in Adv. Enzymol., 1943 (Bibliog. 98)

Laboratory Notebooks  CSAC 113.4.86/D.32  1941-1942

Contents:
Correspondence and papers originally found loose in CSAC 113.4.86/D.31. Includes notices of meetings of Biochemical Society, 29 September 1941, 10 July 1942, at which Krebs gave papers, correspondence with colleagues and one personal letter, 1p. ms. note on proposed alterations to Department of Biochemistry at Sheffield, various experimental data and tabulated results.

Laboratory Notebooks  CSAC 113.4.86/D.33  1942-1944

Contents:
Hardback notebook, pages numbered 1-237 (only) though work continues to end of book. Several loose pages intercalated, and items pasted in. Additional loose items found at rear of book are now at CSAC 113.4.86/D.34.
Entries run 5 August 1942-18 December 1944. Experiments, analyses, tabulated data, with some annotations and re-workings in red ink.
Pasted on to p.231 is a notice of a Biochemical Society meeting, 29 September 1944, at which Krebs gave papers on acetoacetic acid and patulin.

Laboratory Notebooks  CSAC 113.4.86/D.34  1943

Contents:
Miscellaneous shorter notes and correspondence originally found at rear of CSAC 113.4.86/D.33. Includes letter from Vice-Chancellor, Sheffield University, authorising Krebs to accept consultancy with I.C.I. to investigate sulphanilamides, 11 September 1943.

Laboratory Notebooks  CSAC 113.4.86/D.35  1945-1946

Contents:
Brown hardback notebook, inscribed 'H.A. Krebs' inside front cover (in poor condition). Pages numbered 1-76 (only) though work continues to end of book. Some loose pages intercalated. Additional correspondence and material found as loose pages have been removed and now appear at CSAC 113.4.86/D.36.
There is no index; the early entries deal with sulphonamides, the majority with metabolic factors.
Entries run 3 January 1945-6 November 1946. Experimental results, tabulated data, extensive notes on the literature at rear of book.

Laboratory Notebooks  CSAC 113.4.86/D.36  n.d

Contents:
Correspondence and papers originally found loose in CSAC 113.4.86/D.35. on various topics. Includes material on Krebs's and Eggleston's paper on acetoacetic acid (Bibliog. 104), Krebs's and Speakman's paper on sulphonamides (Bibliog. 109) and letter (1p. only) from J. Tosic re collaborative paper (Bibliog. 110)

Laboratory Notebooks  CSAC 113.4.86/D.37  1946-1948

Contents:
Brown ledger-type notebook inscribed 'H.A. Krebs. The University, Sheffield' inside front cover. Pages numbered 1-123 (only) though work continues beyond here and is resumed at rear of book. There is a 'Summary' on p.37 (to June 1947). There are several intercalated pages of notes, and many items pasted in (diagrams, data, correspondence, etc.). Additional correspondence and material found as loose pages have been removed and now appear at CSAC 113.4.86/D.38.
Entries run 7 November 1946-9 September 1948. Experiments, tabulated results, summaries and comments on results, in ink and pencil with annotations and re-workings in red ink. There is a note on p.115 of Krebs's attendance at 'Oxford International Physiological Congress, 21-25 July 1947'. At rear of book, several pages of references, notes on the literature, laboratory rules for Department of Biochemistry, notes on 'Interviewing young applicants', 'Examination questions for Cambridge Tripos', apparatus (one on a sample of Krebs's famous 'Unfit for Medical Research' writing-paper).
Pasted on to p.12 is correspondence with E.J. Morgan, 1946; on p.23 is notice of 'Joint meeting with Leeds biochemists', April 1947; on an unnumbered page is letter from C.R. Harington on synthetic compounds, September 1947; on an unnumbered page is a letter from T.S. Stevens, n.d.; on an unnumbered page is a letter from H. Lüthi, September 1947.

Laboratory Notebooks  CSAC 113.4.86/D.38  1949

Contents:
Correspondence and papers originally found as loose papers in CSAC 113.4.86/D.37. Mainly on specimens and equipment; includes letters from S. Ochoa, C.R. Harington (1949).

Laboratory Notebooks  CSAC 113.4.86/D.39  1962-1963


Related information: See CSAC 113.4.86/D.40.

Contents:
Small black notebook inscribed 'H.A. Krebs. Oxford' inside front cover. Few pages only used, at both ends of book. Work is on 'Control of Gluconeogenesis' and entries run 22 December 1962-3 April 1963.

Laboratory Notebooks  CSAC 113.4.86/D.40  1961-1963

Contents:
Two sets of typescript and ms. notes of experiments to be conducted on gluconeogenesis, various dates 1961-62, and 1963. Originally folded in CSAC 113.4.86/D.39.

Three hardback notebooks kept by M.E. Woodford, 1962-64.  CSAC 113.4.86/D.41-D.43  [n.d.]

Three hardback notebooks kept by M.E. Woodford, 1962-64.  CSAC 113.4.86/D.41  1963

Contents:
'Book I' August-December 1963.

Three hardback notebooks kept by M.E. Woodford, 1962-64.  CSAC 113.4.86/D.42  1963-1964

Contents:
'Book II' December 1963-18 April 1964 (wrongly inscribed April 1963 on cover).

Three hardback notebooks kept by M.E. Woodford, 1962-64.  CSAC 113.4.86/D.43  1964

Contents:
'Book III' April-July 1964 (wrongly inscribed 1963 on cover).
All the work relates to research on Fructose 1, 6-diphosphate in striated muscle. Krebs and Woodford published a collaborative paper on the subject in 1965 (Bibliog. 230).

Two large ledger-type notebooks kept by R.A. Hawkins, 1970-71.  CSAC 113.4.86/D.44, D.45  [n.d.]

Two large ledger-type notebooks kept by R.A. Hawkins, 1970-71.  CSAC 113.4.86/D.44  1970-1971

Contents:
'Determinations' Various dates, July 1970-July 1971.
Experiments for July 27 (no year given) has a ms. note by Krebs.

Two large ledger-type notebooks kept by R.A. Hawkins, 1970-71.  CSAC 113.4.86/D.45  n.d

Contents:
'Results' Data on brain metabolites.
The work refers to the research for the collaborative paper by Krebs, Hawkins and Williamson on 'Ketone-body utilization by adult and suckling rat brain in vivo' (Bibliog. 299).

INDEXED NOTES AND MEMORANDA  CSAC 113.4.86/D.46 - D.100  [n.d.]

Contents:
This designation has been adopted to cover heterogeneous material, mostly received in various folders and binders but some in plastic envelopes (CSAC 113.4.86/D.94 - CSAC 113.4.86/D.96) or as loose papers (CSAC 113.4.86/D.59, CSAC 113.4.86/D.84, CSAC 113.4.86/D.89), the majority bearing a manuscript or typescript list of numbered items included therein. These items may comprise ms. notes or typed-up narratives by Krebs on articles read, experiments performed by him, by colleagues in his research teams or notified to him by others; ideas for research projects, lectures or publications; correspondence enclosing or accompanying information, specimens, preparations or results; reprints or press-cuttings of matters of immediate relevance; summaries of discussions with colleagues in the laboratory, at conferences or on visits. Almost all the material is dated, though the contents of any folder may extend over several years and is not presented in chronological order. Some of the folders have on the spine or cover a note of the main topic, but this is not always the case, nor do the items necessarily conform to the title. It is clear however that the topics kept separately in these folders by Krebs are closely related to or identical with the 'Research Topics' at CSAC 113.4.86/D.101 et seq., and should be regarded as complementary to them.
It has not been considered advisable to retain the material within Krebs's original folders and binders, which were fitted with various types of metal clamp fasteners liable to rust and in any case under strain with the quantity of papers crammed inside. The material is now presented in sequences of one or more folders following Krebs's order and preserving his index and title where these exist. In addition, the summary indications of the original lists have been expanded where appropriate to give a little more detail of the contents. The correspondents are indexed where possible.

Indexed notes and memoranda  CSAC 113.4.86/D.46  1957-1968

Contents:
'Pyruvate kinase'
Contents of a ring-back binder so inscribed.
Assay results, bibliographical references, Krebs's notes.
Various dates, 1957-68.
With typescript index (3 items).

Indexed notes and memoranda  CSAC 113.4.86/D.47  1962-1965

Contents:
'Drugs, substrates, antibodies'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes on the literature, on experiments, on the action of various substances, on enzyme induction by drugs. With some related printed material. Includes note by Krebs dated 24 June 1963 on 'The question of purposefulness'.
Various dates, 1962-65.
With typescript and ms. index (10 items, of which no.9 is missing).

Indexed notes and memoranda  CSAC 113.4.86/D.48  1962-1965

Contents:
'General notes on gluconeogenesis'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes on the literature, on experiments by others, Krebs's research ideas and drafts (includes work on Pasteur effect, gluconeogenesis in lactation, adrenals, etc.). There are also correspondence, related printed matter, experimental results by collaborator.
Various dates, 1962-65.
With typescript index (24 items).

Contents of a bulky ring-back binder. No title, but no. 'I' on front cover and inside front cover. There is no volume II, but CSAC 113.4.86/D.52-CSAC 113.4.86/D.54 were in a binder of the same format.  CSAC 113.4.86/D.49-D.51  [n.d.]

Contents:
Ms. and typescript notes and drafts on various topics in gluconeogenesis, enzyme activity, regulatory and feedback mechanisms. Also includes notes on the literature, and on colleagues' findings, experimental results by L.V. Eggleston and others, some related printed matter, correspondence, graphs, etc. Some of the drafts are substantial, e.g. on 'Fuel of respiration' (no.7 in sequence).
Various dates, 1960-65.
With typescript index (25 items, of which nos.17, 18 are missing).

Contents of a bulky ring-back binder. No title, but no. 'I' on front cover and inside front cover. There is no volume II, but CSAC 113.4.86/D.52-CSAC 113.4.86/D.54 were in a binder of the same format.  CSAC 113.4.86/D.49  1960-1965

Contents:
Index, items 1-5

Contents of a bulky ring-back binder. No title, but no. 'I' on front cover and inside front cover. There is no volume II, but CSAC 113.4.86/D.52-CSAC 113.4.86/D.54 were in a binder of the same format.  CSAC 113.4.86/D.50  1960-1965

Contents:
Items 6-12

Contents of a bulky ring-back binder. No title, but no. 'I' on front cover and inside front cover. There is no volume II, but CSAC 113.4.86/D.52-CSAC 113.4.86/D.54 were in a binder of the same format.  CSAC 113.4.86/D.51  1960-1965

Contents:
Items 13-16, 19-25

Contents of a bulky ring-back binder. No title but same format as CSAC 113.4.86/D.49-CSAC 113.4.86/D.51  CSAC 113.4.86/D.52-D.54  1961-1965

Contents:
Ms. and typescript notes, mainly on aspects of gluconeogenesis and ketosis, metabolism of exercise, etc. Includes research ideas, comments on colleagues' results, related printed matter. Some of the drafts are substantial; item 8, 'Glucose requirements of the body', includes note of visit and discussion (18 January 1963) with E.J.H. Ford; item 16, 'Relations between gluconeogenesis and ketosis', contains notes over several years, 1961-64, includes 'comments by F. Lynen', and a sequence 'partly used at Harvard lecture'; item 23 is a substantial sequence, 1962-65, on 'alloxan diabetes'.
Various dates, 1961-65.
With typescript index (31 items, of which nos. 10 and 22 are missing).

Contents of a bulky ring-back binder. No title but same format as CSAC 113.4.86/D.49-CSAC 113.4.86/D.51  CSAC 113.4.86/D.52  [n.d.]

Contents:
Index, items 1-9

Contents of a bulky ring-back binder. No title but same format as CSAC 113.4.86/D.49-CSAC 113.4.86/D.51  CSAC 113.4.86/D.53  [n.d.]

Contents:
Items 11-21

Contents of a bulky ring-back binder. No title but same format as CSAC 113.4.86/D.49-CSAC 113.4.86/D.51  CSAC 113.4.86/D.54  [n.d.]

Contents:
Items 23-31

Indexed notes and memoranda  CSAC 113.4.86/D.55  1961-1965

Contents:
'Gluconeogenesis. Kidney 1'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes on renal metabolism, including results, ideas, colleagues' results, notes on the literature, bibliographical references, correspondence.
Various dates, 1961-65.
With typescript index (14 items, of which nos. 1-5, 12 and 14 only are numbered. There is an additional item numbered 17).

Indexed notes and memoranda  CSAC 113.4.86/D.56  1962-1965

Contents:
'General gluconeogenesis. Emphasis on Energy 2'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes, ideas, notes on the literature and on colleagues' work, results by L.V. Eggleston, printed matter, correspondence, discussion notes.
Various dates, 1962-65.
With typescript index (21 items, of which no.4 is deleted, nos.12 and 19 are missing).

'General gluconeogenesis. Enzymes 3' Contents of a ring-back binder so inscribed.  CSAC 113.4.86/D.57, D.58  1962-64

Contents:
Ms. and typescript notes, ideas, notes on the literature and on colleagues' results, printed matter, correspondence, bibliographical references. Item 7 is a substantial series, 1963-65, on adenylate kinase; item 13, with correspondence, is on DPN.
Various dates, 1962-64.
With typescript index (25 items, of which no.1 is missing).

'General gluconeogenesis. Enzymes 3' Contents of a ring-back binder so inscribed.  CSAC 113.4.86/D.57  1962 - 1964

Contents:
Index, items 2-14

'General gluconeogenesis. Enzymes 3' Contents of a ring-back binder so inscribed.  CSAC 113.4.86/D.58  1962 - 1964

Contents:
Items 15-25

Indexed notes and memoranda  CSAC 113.4.86/D.59  1962-1963

Contents:
Loose pages of ms. and typescript notes on various factors affecting gluconeogenesis.
Various dates, 1962-63.
No index, but material is numbered 1, 2, 7, 9 and perhaps originally formed part of '4' in this sequence.

Indexed notes and memoranda  CSAC 113.4.86/D.60  1962-1965

Contents:
'Subjects other than gluconeogenesis 5'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes, results, printed matter.
Various dates, 1962-65.
With typescript index (13 items, of which nos.2, 3, 5, 13 are missing).

Indexed notes and memoranda  CSAC 113.4.86/D.61  1962-1965

12 items, of which nos.9, are missing

Contents:
'Liver: glycogen, physiology'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes, ideas, notes on the literature and on methods, bibliographical references, correspondence, discussions with colleagues. Various dates, 1962-65.
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.62  1963, 1964

6 items.

Contents:
'Notes on scientific visits'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes of conversations with colleagues, or of papers heard, at conferences and meetings; mainly research in progress or projected, but includes a little personal material.
Various dates, 1963, 1964.
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.63  1961-1968

20 items, of which no.1 is missing.

Contents:
'Biochemistry notes'
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes, notes on the literature, discussions with colleagues, notes on visit to USA March 1968, printed matter. Item 10 is a note by G.K. Raddo on Warburg's theory of photosynthesis; item 17 is Krebs's notes of a meeting of the Biochemical Society, 1967.
Various dates, 1961-68.
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.64  1964-1965

9 items.

Contents:
'Ketosis'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes, correspondence, printed matter, bibliographical references, experimental results by T. Gascoyne, etc.
Various dates, 1964-65.
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.65  1965

Contents:
'Free energy changes'
Contents of a ring-back binder so inscribed.
One item only, 1965.

Indexed notes and memoranda  CSAC 113.4.86/D.66  1965-1967

Contents:
'Redox states and mitochondria'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes and drafts, correspondence. Item 9 is a substantial draft, 10pp., on 'Redox State of Tissues and Cells', 1965; item 11 is 'Article on Hepatic Coma for Besman's new journal', 1967.
Various dates, 1965-67.
With typescript index (12 items, of which nos.1, 2, 3, 5, 6, 10 are missing).

Indexed notes and memoranda  CSAC 113.4.86/D.67  1965-1967

Contents:
'Redox states'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes and drafts, notes of discussions, on the literature, of further points for discussion, printed matter. Includes draft, 1966, for 'Modena lecture' on 'Some aspects of mitochondrial organisation'.
Various dates, 1965-67.
No index, or numbering of items.

Indexed notes and memoranda  CSAC 113.4.86/D.68  1966-1968

Contents:
'Pyridine nucleotide interrelations'
Contents of a ring-back folder so inscribed.
Ms. and typescript notes, research ideas, drafts, a little related printed matter.
Various dates, 1966-68.
With typescript index (17 items, of which nos.1, 2, 4, 6, 9, 13, 15, 16 are missing).

Indexed notes and memoranda  CSAC 113.4.86/D.69  1967-1968

Contents:
'Pyridine nucleotide interrelations'
Contents of a ring-back binder so inscribed.
Ms. and typescript notes, research ideas, results and calculations, laboratory results by colleague. Item 2 is on rat diets (1968).
Various dates, 1967-68.
With typescript index (10 items, of which nos.1, 3, 5, 8, 9, 10 are missing). There is a ms. note by Krebs 'taken to USA' against nos. 8, 9 and 10).

'Biochemistry'  CSAC 113.4.86/D.70, D.71  1966-1973

Contents:
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts, ideas for future experiments, notes on the literature and on colleagues' results, correspondence, related printed matter. Item 10 is correspondence and drafts on early work by Rosenfeld on carbohydrates.
Various dates, 1966-73.
With typescript index (31 items, of which nos.2, 9, 25 are missing).

'Biochemistry'  CSAC 113.4.86/D.70  [n.d.]

Contents:
Index, items 1, 3-8, 10-15

'Biochemistry'  CSAC 113.4.86/D.71  [n.d.]

Contents:
Items 16-24, 26-31

Indexed notes and memoranda  CSAC 113.4.86/D.72  1970-1971

Contents:
Contents of a spring-clamp binder. No title.
Ms. and typescript notes and drafts, research ideas, discussions with colleagues, notes on the literature, experimental results by L.V. Eggleston (annotated by Krebs), related printed matter. Item 2 is 7pp. draft for proposed work on amino acid degradation; item 10 is a note of discussions on research, lectures, etc. during a visit to America, October 1971; item 6 is a note of a discussion with Brittan Chance, March 1971.
Various dates, 1970-71.
With typescript index (24 items, of which no.3 is missing).

Indexed notes and memoranda  CSAC 113.4.86/D.73  1970-1971

Contents:
'1970-1971'
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts, discussion with colleagues, notes on the literature, ideas for research, correspondence, related printed matter. Item 13 (on diabetes and degenerative eye disorders) is dated 1964.
Various dates, 1970-71 (and on item 1964).
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.74  1971

Contents:
'1971'
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts. Several items are notes of discussions with colleagues on research projects and methods, during a visit to America in July 1971. Item 6 is ms. and typescript versions of a note on 'Blood substitutes' (August 1971).
Various dates, 1971.
With typescript index (7 items, of which no.4 is missing).

'1971'  CSAC 113.4.86/D.75, D.76  [n.d.]

Contents:
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts, research ideas, notes on the literature, discussions with colleagues, results, correspondence, related printed matter. Several of the items deal with work with J.B. Hoek and others on liver metabolism. Item 7 (on Rotenone) is dated 1968.
Various dates, 1968, 1970-71.
With typescript index (14 items, of which no.12 ('Blood substitutes' - see CSAC 113.4.86/D.74) - is missing). There is an additional unlisted item.

'1971'  CSAC 113.4.86/D.75  1968

Contents:
Index, items 1-3

'1971'  CSAC 113.4.86/D.76  [n.d.]

Contents:
Items 4-11, 13-14

Contents of a spring-clamp binder.  CSAC 113.4.86/D.77-D.79  [n.d.]

33 items.

Contents:
No title.
Ms. and typescript notes and ideas, discussions with colleagues, bibliographical references, correspondence, related printed matter, notes on the literature, laboratory results. Item 23 is a bundle of notes, results and printed matter on fructolysis (1975).
Various dates
With typescript index

Contents of a spring-clamp binder.  CSAC 113.4.86/D.77  1972-1975

Contents:
Index, items 1-17

Contents of a spring-clamp binder.  CSAC 113.4.86/D.78  [n.d.]

Contents:
Items 18-23

Contents of a spring-clamp binder.  CSAC 113.4.86/D.79  [n.d.]

Contents:
Items 24-33

Indexed notes and memoranda  CSAC 113.4.86/D.80  1972-1975

Contents:
Contents of a spring-clamp binder.
Ms. and typescript notes and drafts, bibliographical references, research problems, discussions with colleagues, notes on Lipmann Symposium, July 1974 (Item 14), related printed matter, correspondence. Item 26 is a draft on equilibrium systems.
Various dates, 1972-75.
With typescript index (28 items).

'1973'  CSAC 113.4.86/D.81-D.83  [n.d.]

36 items.

Contents:
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts, research ideas, notes on the literature, bibliographical references, comments on colleagues' results and ideas, related printed matter. Many items include correspondence or refer to discussions with colleagues (items 1, 3, 22-24, 32). Item 12 is 'Discussions at Copenhagen meeting 1973'. Item 20 is Krebs's introductory lecture at a meeting of the Society for Experimental Biology at Oxford, 1972, on 'Warburg on Measuring Rates'.
Various dates, 1970-73
With typescript index

'1973'  CSAC 113.4.86/D.81  [n.d.]

Contents:
Index, items 1-11

'1973'  CSAC 113.4.86/D.82  [n.d.]

Contents:
Items 12-20

'1973'  CSAC 113.4.86/D.83  [n.d.]

Contents:
Items 21-36

Indexed notes and memoranda  CSAC 113.4.86/D.84  1969, 1973

Contents:
Loose papers of notes, drafts, research ideas, results by L.V. Eggleston, 1969.
Mainly 1973.
Found inside the binder, but not part of the contents as itemised in the index.

'Liver cells'  CSAC 113.4.86/D.85, D.86  [n.d.]

Contents:
Contents of a spring-clamp binder so inscribed. This binder contained two sets of material each with a ms. index by Krebs, all relating to work on liver cells.

'Liver cells'  CSAC 113.4.86/D.85  1973

Contents:
Ms. and typescript notes, drafts, results, calculations by Krebs and collaborators, notes on the literature. Mainly on CO2 buffers, and on lysine.
Various dates, 1973.
With ms. index (15 items, of which nos.6, 7, 8, 9, 11, 13 are missing).

'Liver cells'  CSAC 113.4.86/D.86  1973

Contents:
Ms. and typescript notes, drafts, results, correspondence, on isolated liver cells and on lysine.
Various dates
With ms. index (11 items, of which nos.2, 3, 4, 5, 6, 8, 11 are missing).

Indexed notes and memoranda  CSAC 113.4.86/D.87  1973-1974

6 items, not numbered.

Contents:
Contents of a spring-clamp binder.
Ms. drafts, laboratory results and experiments, mainly by Krebs but some by collaborators, principally related to work on histidine, lysine and methionine. The dated notes are 1973-74.
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.88  n.d

12 items.

Contents:
Contents of a sprint-clamp binder.
Ms. and typescript notes and drafts, notes on the literature, discussions on research projects, results, correspondence, related printed matter. Includes material on histidine metabolism, Crassulacae, lysine, etc.
With typescript index

Indexed notes and memoranda  CSAC 113.4.86/D.89  1973-1975

Contents:
Loose pages of notes, drafts, printed matter, originally tucked into D.88 but not figuring in the index.
Various dates, 1973-75.

Indexed notes and memoranda  CSAC 113.4.86/D.90  1970, 1974

Contents:
Contents of a spring-clamp binder.
Ms. and typescript notes and drafts, notes on the literature. There are a few notes on proline dated 1970, but most of the material is dated 1974 and deals with equilibrium reactions. Some of it, headed 'Indianapolis' probably refers to Krebs's lecture in 1974 (Bibliog. 341).
There is no index.

Indexed notes and memoranda  CSAC 113.4.86/D.91  1974-1977

Contents:
Contents of a spring-clamp binder.
Ms. and typescript notes and drafts, results, notes on books and articles, discussions with colleagues, correspondence, related printed matter, bibliographical references, research data from collaborators.
Various dates, 1974-77.
There is no index.

Contents of a spring-clamp binder.  CSAC 113.4.86/D.92, D.93  1975

22 items.

Contents:
No title.
Ms. notes and drafts, bibliographical references, notes on 'Valencia meeting' (1975), correspondence, printed matter including some on sociobiological problems. Item 21 is a substantial assemblage of material on chirality.
Various dates, 1975.
With typescript index

Contents of a spring-clamp binder.  CSAC 113.4.86/D.92  [n.d.]

Contents:
Index, items 1-20

Contents of a spring-clamp binder.  CSAC 113.4.86/D.93  [n.d.]

Contents:
Items 21, 22

Indexed notes and memoranda  CSAC 113.4.86/D.94  1980-1981

Contents:
Contents of a plastic envelope, perhaps intended to be incorporated in a binder.
Ms. notes and drafts, notes on books and articles, research ideas. Several items relate to evolution of metabolic cycles.
Various dates, 1980-81, and some undated items.
With typescript index (18 items, of which nos. 1, 2, 4, 11, 12, 13, 14, 17 are missing).

Contents of a plastic envelope, perhaps intended to be incorporated in a binder.  CSAC 113.4.86/D.95, D.96  1980-1981,nd

Contents:
Ms. and typescript drafts, comments on ideas of others, notes on books and articles, printed matter and press-cuttings. Much of the material relates to the Dunham lectures given at Harvard in 1981 and to work on evolutionary theory.
Various dates, 1980-81, and some undated items.
With typescript index (21 items, of which nos.11, 20 are missing).

Contents of a plastic envelope, perhaps intended to be incorporated in a binder.  CSAC 113.4.86/D.95  [n.d.]

Contents:
Index, items 1-10, 12, 13

Contents of a plastic envelope, perhaps intended to be incorporated in a binder.  CSAC 113.4.86/D.96  [n.d.]

Contents:
Items 14-19, 21

Contents of three spring-clamp binders kept by Krebs specifically as 'Research projects' or 'Biochemical problems'. The contents do not differ significantly from others in the sequence which he identified by topic or by year.  CSAC 113.4.86/D.97-D.100  [n.d.]


Related information: See also CSAC 113.4.86/D.207 for similar material kept with the research projects in hand.

Contents of three spring-clamp binders kept by Krebs specifically as 'Research projects' or 'Biochemical problems'. The contents do not differ significantly from others in the sequence which he identified by topic or by year.  CSAC 113.4.86/D.97  1962-1969

6 items.

Contents:
'Research projects'
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts, notes on the literature, experimental results, correspondence, related printed matter; mainly on aspects of ketosis, and calcium effect on gluconeogenesis.
Various dates, 1962-69.
With typescript index

Contents of three spring-clamp binders kept by Krebs specifically as 'Research projects' or 'Biochemical problems'. The contents do not differ significantly from others in the sequence which he identified by topic or by year.  CSAC 113.4.86/D.98  1968-1970

Contents:
'Biochemical problems'
Contents of a spring-clamp binder so inscribed.
Ms. and typescript notes and drafts, discussions with colleagues, research ideas and methods, notes on the literature, bibliographical references, results by L.V. Eggleston and others, correspondence, related printed matter. Item 3 (1968) 'General comment on redox work' is a draft for a talk or lecture.
Various dates, 1968-70, except for item 20 'Saline Media' (1963) and item 21 'Alcaligenes' (1961).
With typescript index

[no title]  CSAC 113.4.86/D.99, D.100  1967-1970

Contents:
'Biochemical Problems 1969-70'
Ms. and typescript notes and drafts, research ideas, discussions with colleagues, notes on the literature, experimental results, correspondence, related printed matter, bibliographical references. Item 5 (1969) is a draft on 'Changes in Redox State under Anaerobic Conditions'; item 22 (1970) is a note of discussions at 'Marburg Symposium'; item 25 (1970) is a substantial assemblage of material on 'microsomal mixed function oxidases'.
Various dates, 1967-70.
With typescript index (34 items, of which nos.10 and 27, both on proline, are missing.

Contents of three spring-clamp binders kept by Krebs specifically as 'Research projects' or 'Biochemical problems'. The contents do not differ significantly from others in the sequence which he identified by topic or by year.  CSAC 113.4.86/D.99  [n.d.]

Contents:
Index, items 1-9, 11-20

Contents of three spring-clamp binders kept by Krebs specifically as 'Research projects' or 'Biochemical problems'. The contents do not differ significantly from others in the sequence which he identified by topic or by year.  CSAC 113.4.86/D.100  [n.d.]

Contents:
Items 21-26, 28-34

RESEARCH PROJECTS  CSAC 113.4.86/D.101 - D.514  [n.d.]

Contents:
This covers the bulk of Krebs's research activity 1951 - 81. It is presented as a chronological sequence of topics, each dated from the first surviving notes or records. Krebs's own designations, where they existed on the original folders and boxes, have been retained. Un-named material has been supplied with an appropriate descriptive title on advice from Krebs's colleagues.
Some of the topics are very substantial, extending over a long time-span and covering research ideas, laboratory work by Krebs and others, multiple drafts for lectures and publications, discussions with colleagues, scientific and editorial correspondence, background and bibliographical material. Others are brief, perhaps just a note for possible future research or a collection of annotated offprints on a topic to be explored later. Generally speaking, however, this can be said to form the basic material for Krebs's research, lectures and publications. Efforts have therefore been made to link the work with the published papers, references being given in the form (Bibliog....) and also appearing in the Conspectus. Correspondents are indexed and colleagues identified where possible.
CSAC 113.4.86/D.101-CSAC 113.4.86/D.111 TELEOLOGY 1951-54, 1961
CSAC 113.4.86/D.112 BUFFER SOLUTIONS c.1955
CSAC 113.4.86/D.113-CSAC 113.4.86/D.120 STEERING AND FEEDBACK MECHANISMS 1955-65
CSAC 113.4.86/D.121-CSAC 113.4.86/D.124 KETOGENESIS / PYRUVATE METABOLISM 1955-65
CSAC 113.4.86/D.125-CSAC 113.4.86/D.128 SPECIFIC DYNAMIC ACTION OF FOODSTUFFS 1957-63
CSAC 113.4.86/D.129-CSAC 113.4.86/D.131 ANTERIOR PITUITARY HORMONES IN KETOGENESIS 1959-62
CSAC 113.4.86/D.132-CSAC 113.4.86/D.138 KETOGENESIS / INSULIN 1959-65
CSAC 113.4.86/D.139-CSAC 113.4.86/D.157 REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REDUCTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64
CSAC 113.4.86/D.158 OXALOACETATE AND SUCCINIC DEHYDROGENASE 1961-66
CSAC 113.4.86/D.159, CSAC 113.4.86/D.160 CO2 BUFFERS IN MANOMETRY 1961
CSAC 113.4.86/D.161-CSAC 113.4.86/D.164 GROWTH AND ENERGY 1962
CSAC 113.4.86/D.165 CONTROL OF GLUCONEOGENESIS 1962-63
CSAC 113.4.86/D.166 'CITRULLINE' SPOT 1962-63
CSAC 113.4.86/D.167-CSAC 113.4.86/D.174 MUSCLE METABOLISM 1962-64, 1967
CSAC 113.4.86/D.175-CSAC 113.4.86/D.177 PYRUVATE CARBOXYLASE 1962-66
CSAC 113.4.86/D.178-CSAC 113.4.86/D.180 KETONE BODIES 1963-65
CSAC 113.4.86/D.181, CSAC 113.4.86/D.182 ENZYME ASSAYS 1963-66
CSAC 113.4.86/D.183-CSAC 113.4.86/D.187 ISOTOPE EXCHANGES 1963-70
CSAC 113.4.86/D.188-CSAC 113.4.86/D.205 ISOLATED LIVER CELLS 1963-77
CSAC 113.4.86/D.206 ASPARTATE c.1964
CSAC 113.4.86/D.207 RESEARCH PROBLEMS 1964-67
CSAC 113.4.86/D.208 DRUG-INDUCED DIABETES 1965
CSAC 113.4.86/D.209 CALORIC HOMEOSTASIS 1965
CSAC 113.4.86/D.210-CSAC 113.4.86/D.222 ALANINE 1965-73
CSAC 113.4.86/D.223-CSAC 113.4.86/D.238 REDOX STATE 1965-76
CSAC 113.4.86/D.239, CSAC 113.4.86/D.24 INTRACELLULAR pH 1966-71
CSAC 113.4.86/D.241 ADIPOSE TISSUE 1967
CSAC 113.4.86/D.242 ROTENONE AND KETOSIS 1967
CSAC 113.4.86/D.243 NUTRIENTS c.1967
CSAC 113.4.86/D.244 CARNITINE 1967, 1969
CSAC 113.4.86/D.245 HEPATOTOXIC AGENTS 1967-68
CSAC 113.4.86/D.246 HUMAN LIVER DATA 1967-68
CSAC 113.4.86/D.247-CSAC 113.4.86/D.249 KETOGENESIS / REGULATION OF TCA CYCLE 1968
CSAC 113.4.86/D.250 EXTRAHEPATIC KETOGENESIS 1968-69
CSAC 113.4.86/D.251-CSAC 113.4.86/D.253 ALCOHOL IN ANIMALS 1968-70
CSAC 113.4.86/D.254 HOMEOSTASIS 1968-71
CSAC 113.4.86/D.255-CSAC 113.4.86/D.261 METABOLISM OF ACETALDEHYDE 1968-77
CSAC 113.4.86/D.262-CSAC 113.4.86/D.266 RATE CONTROL OF TCA CYCLE 1968-69
CSAC 113.4.86/D.267-CSAC 113.4.86/D.271 METABOLISM OF WORKING HEART 1969-72
CSAC 113.4.86/D.272-CSAC 113.4.86/D.274 MITOCHONDRIA 1969-71
CSAC 113.4.86/D.275-CSAC 113.4.86/D.288 INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY 1969-75
CSAC 113.4.86/D.289 GLUCOSE FFA CYCLE 1970
CSAC 113.4.86/D.290 HORMONES AND GLUCONEOGENESIS 1970
CSAC 113.4.86/D.291 INTERMEDIATE LIVER METABOLISM 1970-72
CSAC 113.4.86/D.292, CSAC 113.4.86/D.293 PASTEUR EFFECT 1970-71
CSAC 113.4.86/D.294-CSAC 113.4.86/D.304 AMINOTRANSFERASES 1970-72
CSAC 113.4.86/D.305-CSAC 113.4.86/D.307 OXIDATIVE PHOSPHORYLATION 1971
CSAC 113.4.86/D.308, CSAC 113.4.86/D.309 KETONE BODY METABOLISM IN DIABETES 1971
CSAC 113.4.86/D.310 ADIPOSE TISSUE 1971
CSAC 113.4.86/D.311-CSAC 113.4.86/D.313 REDOX STATE IN BACTERIA 1971-72
CSAC 113.4.86/D.314-CSAC 113.4.86/D.316 REVERSIBILITY OF RESPIRATORY CHAIN 1971-74
CSAC 113.4.86/D.317 ALCOHOL METABOLISM IN LIVER 1971-74
CSAC 113.4.86/D.318-CSAC 113.4.86/D.329 RETINAL METABOLISM 1971-72
CSAC 113.4.86/D.330 SALINE MEDIA 1971, 1976
CSAC 113.4.86/D.331-CSAC 113.4.86/D.341 CALORIMETRY 1971-77
CSAC 113.4.86/D.342 ACETYLGLUTAMATE 1972
CSAC 113.4.86/D.343 UREA CYCLE 1972
CSAC 113.4.86/D.344-CSAC 113.4.86/D.348 AMINO ACID ANALYSES IN LIVER CELLS 1972-74
CSAC 113.4.86/D.349-CSAC 113.4.86/D.358 GLUCONEOGENESIS AND UREA SYNTHESIS 1972-74
CSAC 113.4.86/D.359-CSAC 113.4.86/D.372 PENTOSE-PHOSPHATE CYCLE 1972-74
CSAC 113.4.86/D.373-CSAC 113.4.86/D.378 6-AMINO-NICOTINAMIDE 1972-77
CSAC 113.4.86/D.379 COMPETITION BETWEEN SHORT- AND LONG-CHAIN FATTY ACIDS IN PERFUSED RAT LIVER [1973]
CSAC 113.4.86/D.380 SULPHONAMIDES 1973-74
CSAC 113.4.86/D.381 FLUOROCARBONS 1973-74
CSAC 113.4.86/D.382-CSAC 113.4.86/D.395 OVER-MEDICATION 1973-78
CSAC 113.4.86/D.396 CRASSULACEAE 1974
CSAC 113.4.86/D.397 CARNOSINE 1974
CSAC 113.4.86/D.398, CSAC 113.4.86/D.399 SHUTTLES AND CARRIERS 1974
CSAC 113.4.86/D.400-CSAC 113.4.86/D.408 HYPERLACTATAEMIA AND LACTIC ACIDOSIS 1974
CSAC 113.4.86/D.409-CSAC 113.4.86/D.414 RENAL AMMONIA 1974
CSAC 113.4.86/D.415-CSAC 113.4.86/D.435 FOLATE/B12/METHIONINE/HISTIDINE 1974-78
CSAC 113.4.86/D.436 PENTENOATE 1975
CSAC 113.4.86/D.437 L-GLUTAMATE TRANSPORT IN HEPATOCYTES 1975
CSAC 113.4.86/D.438, CSAC 113.4.86/D.439 LACTATE 1975-76
CSAC 113.4.86/D.440-CSAC 113.4.86/D.444 METABOLISM OF BRANCHED-CHAIN AMINO ACIDS 1975-76
CSAC 113.4.86/D.445 CHICK ENTEROCYTES 1977
CSAC 113.4.86/D.446-CSAC 113.4.86/D.449 PURINE SYNTHESIS 1977-81
CSAC 113.4.86/D.450 GLUCAGON AND INSULIN IN BIRDS 1978
CSAC 113.4.86/D.451-CSAC 113.4.86/D.453 GLUTAMINE METABOLISM 1978-79
CSAC 113.4.86/D.454 CALCIUM CONCENTRATION IN SALINE 1979
CSAC 113.4.86/D.455-CSAC 113.4.86/D.458 BENZOATE 1979-81
CSAC 113.4.86/D.459-CSAC 113.4.86/D.511 EVOLUTION OF METABOLIC PATHWAYS 1979-81
With an introductory note
CSAC 113.4.86/D.51 CITRATE CYCLE 1980
CSAC 113.4.86/D.513, CSAC 113.4.86/D.514 HEPATOCYTES 1981

TELEOLOGY  CSAC 113.4.86/D.101-D.111  1951-54, 1961


Related information: See also CSAC 113.4.86/A.118, CSAC 113.4.86/F.23-CSAC 113.4.86/F.46.

Contents:
Krebs assembled ideas and references on the subject during 1951-52. He gave lectures and may have contemplated a more extended work (see CSAC 113.4.86/D.104). His main published contribution (Bibliog. 168) was part of the Herter lectures given at Johns Hopkins University; he also gave a joint talk on 'Frontiers in Biochemistry' with F. Lipmann at a 'Smoker' during a meeting of the American Society of Chemists at Atlantic City during his extended visit to America in 1954.

TELEOLOGY  CSAC 113.4.86/D.101  1951

Contents:
Notes and quotations from Ernst Cassirer: The Problem of Knowledge, 1p. headed 'Teleology' has a ms. note 'Discussion with Cassier 23/8/51'.
In Krebs's original folder, labelled 'Teleology'.

TELEOLOGY  CSAC 113.4.86/D.102  1951-1952

Contents:
Correspondence, 1951-52.
Includes letter from F. Brücke on his great-grandfather, Ernst Brücke, whose work is widely quoted by Krebs in his lectures and writing.

TELEOLOGY  CSAC 113.4.86/D.103  1952

Contents:
'Teleological Considerations in Biology'
Two heavily-corrected ms. and typescript drafts, 10pp. and 13pp., the latter with a ms. headnote 'Lecture before Philosophical Society 22.2.52.

TELEOLOGY  CSAC 113.4.86/D.104  n.d

Contents:
'Postcript. The teleological viewpoint in biology'
3 heavily-corrected ms. and typescript drafts, and final 7pp. typescript version, all with this title, using similar material to CSAC 113.4.86/D.103 above. The drafts begin 'In this book the assumption is made ...' and refer to 'this chapter', but there is no substantial work by Krebs on the subject listed in the Bibliography.

TELEOLOGY  CSAC 113.4.86/D.105  n.d

Contents:
'Excursion into the borderland of biochemistry and philosophy'
Heavily-corrected typescript and ms. drafts for lecture (Bibliog. 168).

TELEOLOGY  CSAC 113.4.86/D.106  n.d

Contents:
Similar ms. and typescript drafts, no title or date but perhaps an earlier version of CSAC 113.4.86/D.105.

[no title or date]  CSAC 113.4.86/D.107-D.109

Contents:
'Frontiers in biochemistry'
2 heavily-corrected ms. and typescript drafts, for talk with Lipmann at Atlantic City, with Krebs's carbon letter to Lipmann discussing arrangements. The talk has a ms. note by Krebs 'Good paper'.

TELEOLOGY  CSAC 113.4.86/D.108  n.d

Contents:
More fragmentary notes and drafts.

TELEOLOGY  CSAC 113.4.86/D.109  n.d

Contents:
Notes, references, background material.

[no title or date]  CSAC 113.4.86/D.110, D.111

Contents:
Later correspondence and papers, 1961.

TELEOLOGY  CSAC 113.4.86/D.110  1961

Contents:
Correspondence with L. Rosenfeld on possible exchange of views on the subject. With a little background material.

TELEOLOGY  CSAC 113.4.86/D.111  1961

Contents:
Krebs's notes and drafts on teleology, complementarity, etc., various dates May-September 1961. With a little background material.

BUFFER SOLUTIONS  CSAC 113.4.86/D.112  n.d, c1955

Contents:
Brief notes, references, data. n.d., c.1955. With related background material, some annotated.

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.113-D.120  1955-65

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.113  1955

Contents:
'Die Steuering der Stoffwechselvorgänge'
Typescript draft, with a few ms. corrections and covering letter, October 1955.
(Bibliog. 179)

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.114  1960,1936

Contents:
'Regulation of Metabolism'
17pp. typescript and ms. draft for lecture. With a ms. headnote 'Ann Arbor March 1960' and 'Jerusalem April 1936'.

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.115  n.d

Contents:
14pp. typescript lecture or article on regulation of metabolism. No date or place.
Included here are offprints of two of Krebs's publications on the subject (Bibliog. 178, 187).

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.116  1955, 1959, 1962

Contents:
Notes, drafts, discussions. Few dated. Includes note of discussion with H. Motz on origin of term 'feedback' 1955, and other notes, 1959, 1962.

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.117  n.d

Contents:
Ms. and typescript bibliographical references.

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.118  n.d

Contents:
Background material, some annotated.

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.119  1963, 1965

Contents:
Ms. notes on feedback mechanisms, 1963, 1965. With a ms. note by Krebs 'Regulation (earlier refs) collected for Physiol. Review (never written)'.

STEERING AND FEEDBACK MECHANISMS  CSAC 113.4.86/D.120  n.d

Contents:
Background material, some annotated.

KETOGENESIS / PYRUVATE METABOLISM 1955-56  CSAC 113.4.86/D.121-D.124  [n.d.]

KETOGENESIS / PYRUVATE METABOLISM 1955-56  CSAC 113.4.86/D.121  1955-1957

Contents:
Typescript draft with a few ms. corrections, and tables for an untitled paper; the accompanying experimental results have various dates, 1955-57.

KETOGENESIS / PYRUVATE METABOLISM 1955-56  CSAC 113.4.86/D.122  1964

Contents:
Miscellaneous references, some dated 1964, and headed 'Deuel Conference paper'.

KETOGENESIS / PYRUVATE METABOLISM 1955-56  CSAC 113.4.86/D.123  1962,1965

Contents:
Brief correspondence on bovine ketosis, 1962.
Later notes and drafts, March-April 1965.

KETOGENESIS / PYRUVATE METABOLISM 1955-56  CSAC 113.4.86/D.124  n.d

Contents:
Offprints and background material, some annotated.

SPECIFIC DYNAMIC ACTION OF FOODSTUFFS 1957-63  CSAC 113.4.86/D.125-D.128  [n.d.]

Contents:
Only one publication on this topic is listed (Bibliog. 194), a paper given at the Rona Symposium.

SPECIFIC DYNAMIC ACTION OF FOODSTUFFS 1957-63  CSAC 113.4.86/D.125  1957, 1958; 1959

Contents:
Ms. and typescript notes and drafts, some dated 1957, 1958.
Heavily-corrected ms. and typescript drafts, some dated 1959 and referring to work of K.L. Blaxter.

SPECIFIC DYNAMIC ACTION OF FOODSTUFFS 1957-63  CSAC 113.4.86/D.126  n.d

Contents:
Undated ms. and typescript drafts, bibliography, references, with a short ms. list of contents.

SPECIFIC DYNAMIC ACTION OF FOODSTUFFS 1957-63  CSAC 113.4.86/D.127  1961,1962

Contents:
Later ms. and typescript notes, drafts, experimental results (by Krebs and some by P. Lund). Includes figures for publication, and a copy of Bibliog. 194 with updated bibliography. Various dates, 1961, 1962.

SPECIFIC DYNAMIC ACTION OF FOODSTUFFS 1957-63  CSAC 113.4.86/D.128  1960,1963

Contents:
Correspondence and discussion with colleagues on experiments, techniques, results, 1960-63. Includes a little related background material and notes by Krebs of discussions.

ANTERIOR PITUITARY HORMONES IN KETOGENESIS 1959-62  CSAC 113.4.86/D.129-D.131  [n.d.]

ANTERIOR PITUITARY HORMONES IN KETOGENESIS 1959-62  CSAC 113.4.86/D.129  1959,-1962

Contents:
Correspondence with colleagues, institutions and firms about specimens and supplies for proposed research, 1959-62.

ANTERIOR PITUITARY HORMONES IN KETOGENESIS 1959-62  CSAC 113.4.86/D.130  1960-1961, 1966

Contents:
Research notes and data, suggestions for experiments, bibliographical references, by Krebs and collaborator. August 1960-September 1961 (and one page later data, August 1966).

ANTERIOR PITUITARY HORMONES IN KETOGENESIS 1959-62  CSAC 113.4.86/D.131  n.d

Contents:
Background material.

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.132-D.138  [n.d.]

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.132  1964

Contents:
Ms. and typescript notes and drafts, references, discussions with colleagues (some on writing-paper of HMS 'Queen Elizabeth') none dated, correspondence (1964).

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.133  n.d

Contents:
Bibliographical references.

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.134  n.d

Contents:
Draft paper by Krebs, contributing to discussion arising from a presentation by C.H. Best on 'Metabolic problems involving the pancreas, insulin and glucagon'. n.d., latest reference 1959.

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.135  n.d

Contents:
'Biochemical Aspects of Ketosis'
11pp. duplicated typescript, with ms. headnote 'Amended Copy'. Perhaps earlier version of Ernest Dixon Memorial Lecture of same title (Bibliog. 193).

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.136  1960,1961

Contents:
'The Biochemical lesion in Ketosis'
3 drafts (all different) of paper given at Chicago, March 1960, and published 1961 (Bibliog. 198), in Krebs's original folder labelled 'Ketosis in Chicago'.

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.137  n.d

Contents:
Offprints of Krebs's published papers on the subject, kept with the material (Bibliog. 193, 198, 200, 236). Included here is his 'Inaugural Lecture: Some Aspects of Gluconeogenesis (The Relations between Gluconeogenesis and Ketogenesis)', given at the Third Symposium, on Energy Metabolism, of the European Association for Animal Production, held at Troon, May 1964 and published in the Proceedings (Academic Press, 1965); this publication is not listed in the Bibliography.

KETOGENESIS / INSULIN 1959-65  CSAC 113.4.86/D.138  n.d

Contents:
Background material sent to or requested by Krebs, some annotated.

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.139-D.157  [n.d.]

Contents:
Contents of a box so labelled, comprising notes, drafts, correspondence, etc. relating to collaborative work principally with L.V. Eggleston (Bibliog. 199, 202, 208, 209). Krebs's original folders, some with descriptions, are at CSAC 113.4.86/D.157. See also CSAC 113.4.86/D.158 which is a continuation of similar work, also with Eggleston, but kept separately by Krebs.

[no title or date]  CSAC 113.4.86/D.139-D.141

Contents:
Ms. and typescript notes and drafts, almost all by Krebs but a few by Eggleston. Not all dated. Many relate to Bibliog. 199.
Three folders as follows:

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.139  1960-1961

Contents:
November 1960-July 1961

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.140  1961, nd

Contents:
September-November 1961 and undated 'Draft of LVE'

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.141  1963, nd

Contents:
April-December 1963 and undated.

[no title or date]  CSAC 113.4.86/D.142-D.146

Contents:
Experimental data, tabulated results, calculations, etc., chiefly by Eggleston but with many ms. notes, suggestions for further experiments, etc. by Krebs.
Five folders as follows:

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.142  1960

Contents:
January-September 1960

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.143  November-December 1960

Contents:
Papers

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.144  January-October 1961

Contents:
Papers

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.145  1962

Contents:
Papers

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.146  August-November 1963

Contents:
Some headed '"Klingenberg" expts.'

[no title or date]  CSAC 113.4.86/D.147-D.152

Contents:
Publications and lectures

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.147  n.d

Contents:
Draft for slide lecture, 21pp. typescript.

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.148  n.d

Contents:
Part draft for slide lecture (different from above).

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.149  n.d

Contents:
Part draft for publication, with tables, on oxidation of succinate.

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.150  n.d, 1961

Contents:
Notes, drafts, references, some dated 1961.
All the above were in original folder labelled 'Welch Raw Material' and probably refer to Krebs's 1961 Welch lecture 'Biological reductions in complex systems' (Bibliog. 202).

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.151  1962, 1963

Contents:
'The effect of dinitrophenol on the metabolism of oxaloacetate in animal tissues'
Heavily-corrected ms. and typescript drafts for a paper so titled, by Krebs and Eggleston, various dates, March 1962, October and December 1963, and undated.
No paper of this title is listed in the Bibliography, and it was probably not published (R. Hems, personal communication, 1984).

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.152  1964

Contents:
Ms. notes for lecture on the subject given for 'Biochemistry Part II', 22 January 1964.

[no title or date]  CSAC 113.4.86/D.153-D.155

Contents:
Correspondence

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.153  1960

Contents:
Bücher, T.
Chance, B. 1960

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.154  1960, 1963

Contents:
Ernster, L. 1960
Klingenberg, M.

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.155  1964

Contents:
Chance, B.
Krebs's carbon only, on further research on reversal of oxidative phosphorylation. With related printed matter.

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.156  n.d

Contents:
Background material, some annotated.

REVERSAL OF OXIDATIVE PHOSPHORYLATION / ATP DEPENDENT REACTIONS / SECONDARY EFFECTS OF DINITROPHENOL 1960-64  CSAC 113.4.86/D.157  n.d

Contents:
Krebs's original folders and box description.

OXALOACETATE AND SUCCINIC DEHYDROGENASE 1961-66  CSAC 113.4.86/D.158  [n.d.]

Contents:
Continuing work with L.V. Eggleston. Includes some earlier data and drafts, 1961-62, another draft of unlisted paper on effect of DNP (see CSAC 113.4.86/D.151 above), continuing drafts by Krebs 1963-66, and a substantial 12pp. draft by Krebs and Eggleston on 'Metabolism of Oxaloacetate'.

CO2 BUFFERS IN MANOMETRY 1961  CSAC 113.4.86/D.159, D.160  [n.d.]

CO2 BUFFERS IN MANOMETRY 1961  CSAC 113.4.86/D.159  1961

Contents:
Notes, drafts, bibliographical references, notes on the literature, correspondence from suppliers of 'Warburg Flasks', June-September 1961.

CO2 BUFFERS IN MANOMETRY 1961  CSAC 113.4.86/D.160  n.d

Contents:
Offprints of articles by O. Warburg on manometry, and of Krebs's earlier (1951) articles on the subject (Bibliog. 140, 147).

GROWTH AND ENERGY 1962  CSAC 113.4.86/D.161-D.164  [n.d.]

GROWTH AND ENERGY 1962  CSAC 113.4.86/D.161  1962

Contents:
Ms. and typescript notes, drafts, calculations, research ideas, references. A few only dated, January, April 1962.
In Krebs's original folder, labelled 'Growth and energy'.

[no title or date]  CSAC 113.4.86/D.162-D.164

Contents:
Correspondence with colleagues, 1962

GROWTH AND ENERGY 1962  CSAC 113.4.86/D.162  1963

Contents:
Elsden, S.R.
Includes copies of Elsden's reports on growth and energy to the A.R.C. Correspondence June includes invitation to Krebs to chair a session of the Society for General Microbiology symposium on 'Comparative Aspects of Microbial Metabolism', in Sheffield, January 1963.

GROWTH AND ENERGY 1962  CSAC 113.4.86/D.163  n.d

Contents:
Stoward, P.J.
Includes report by Stoward to D.S.I.R. on Thermodynamics of bacterial growth.

GROWTH AND ENERGY 1962  CSAC 113.4.86/D.164  n.d

Contents:
Zamecnik, P.
Zeuthen, E.

CONTROL OF GLUCONEOGENESIS 1962-63  CSAC 113.4.86/D.165  1962-1963

Contents:
24pp. ms. notes and drafts, in spiral-bound foolscap pad, various dates December 1962-January 1963.
Includes research ideas, experiments, discussions with colleagues, notes on the literature, etc. The work, though heterogeneous in nature, is dated continuously from 22 December to 5 January, including Christmas Day, and may represent Krebs's reading and thinking when the laboratory was closed for Christmas. Note for 3 January on 'Citrulline' appears in a typed version in CSAC 113.4.86/D.166 below.

'CITRULLINE' SPOT 1962-63  CSAC 113.4.86/D.166  1962-1963

Contents:
Notes, drafts, correspondence, experimental results, by R.Hems and another, August 1962-January 1963. Includes copy of paper by Derks and Grisolia on 'Citrulline-like Material' and of Krebs's ms. and typescript notes on the subject.
In Krebs's original folder.

MUSCLE METABOLISM  CSAC 113.4.86/D.167-D.174  1962-64, 1967

Contents:
Drafts, notes, correspondence, mainly concerned with lactate in exercise.

[no title or date]  CSAC 113.4.86/D.167-D.169

Contents:
Krebs's dated notes, drafts, research ideas and discussions, experimental results, bibliographical references. Three folders as follows:

MUSCLE METABOLISM  CSAC 113.4.86/D.167  1962

Contents:
Papers

MUSCLE METABOLISM  CSAC 113.4.86/D.168  1963

Contents:
Papers

MUSCLE METABOLISM  CSAC 113.4.86/D.169  May, September-October 1963

Contents:
Carbohydrate synthesis in striated muscle; correspondence, substantial drafts and narratives

MUSCLE METABOLISM  CSAC 113.4.86/D.170  October 1963

Contents:
Undated notes, bibliographical references; includes some data by L.V. Eggleston

MUSCLE METABOLISM  CSAC 113.4.86/D.171  1963-1964

Contents:
Brief publications and papers by Krebs.
Includes contribution to discussion of the 'Oxygen Symposium' sponsored jointly by the International Unions of Biochemistry and Physiological Sciences at Oxford, September 1963, and notes for paper on 'Some aspects of the metabolism of muscular exercise' given at a seminar in the Department of Physiology, Oxford, June 1964 (arising in part from 1963 Symposium and subsequent research and correspondence with D. Cunningham, B.B. Lloyd - see CSAC 113.4.86/D.172 below).

MUSCLE METABOLISM  CSAC 113.4.86/D.172  1963-64

Contents:
Correspondence
Cunningham, D.
Lloyd, B.B.
Masoro, E.J.
Olson, R.E.

MUSCLE METABOLISM  CSAC 113.4.86/D.173  1967

Contents:
Correspondence with R.E. Davies, 1967, on early work on muscle metabolism. Includes a draft of letter by Krebs to A.V. Hill on same subject.

MUSCLE METABOLISM  CSAC 113.4.86/D.174  n.d

Contents:
Background material, some annotated.

PYRUVATE CARBOXYLASE 1962-66  CSAC 113.4.86/D.175-D.177  [n.d.]

PYRUVATE CARBOXYLASE 1962-66  CSAC 113.4.86/D.175  1962-1966

Contents:
Notes and drafts by Krebs. Various dates, 1962-66. Includes 4pp. draft by L.V. Eggleston 'Location of pyruvate carboxylase', October 1966.
In original folder labelled 'Pyruvate Carboxylase'.

PYRUVATE CARBOXYLASE 1962-66  CSAC 113.4.86/D.176  1964-1966

Contents:
Experimental assays and results, mainly by Eggleston, with a few notes by Krebs, various dates, 1964-66.

PYRUVATE CARBOXYLASE 1962-66  CSAC 113.4.86/D.177  1967

Contents:
Drafts and notes by W. Gevers and Krebs for collaborative paper 'The regulation of phosphoenolpyruvate synthesis in pigeon liver', published 1967 (Bibliog. 244).

KETONE BODIES 1962-65  CSAC 113.4.86/D.178-D.180  [n.d.]


Related information: See also CSAC 113.4.86/D.130.

Contents:
Correspondence, drafts, data exchanged with L. Kastner, relating to her research and publications on ketone bodies in rat-liver preparations.

KETONE BODIES 1962-65  CSAC 113.4.86/D.178  1964

Contents:
Notes, drafts, amendments by Krebs, some dated 1964.

KETONE BODIES 1962-65  CSAC 113.4.86/D.179  1963-65

Contents:
Correspondence, data and drafts from L. Kastner

KETONE BODIES 1962-65  CSAC 113.4.86/D.180  n.d

Contents:
Miscellaneous drafts, some with Krebs's amendments.
Final 10pp. typescript version.

ENZYME ASSAYS 1963-66  CSAC 113.4.86/D.181, D.182  [n.d.]

Contents:
Contents of two folders so described, of notes, drafts, experimental data by Krebs and L.V. Eggleston.

ENZYME ASSAYS 1963-66  CSAC 113.4.86/D.181  1963-1964

Contents:
Extensive notes and drafts, mainly by Krebs but some by Eggleston annotated by Krebs. Various dates, September 1963-March 1966.
Notes of September 1963 and July 1964 are general ideas on 'Significance of enzyme assays'; several notes are on 'Assay of pyruvate carboxylase'; note of July 1965 is a draft for a proposed paper by Eggleston and Krebs 'The capacity of enzymes related to gluconeogenesis in rat liver and rat kidney cortex'.

ENZYME ASSAYS 1963-66  CSAC 113.4.86/D.182  1965

Contents:
Ms. drafts for papers, experimental data, tables, results, etc. almost all by Eggleston, with a few ms. notes by Krebs. July-October 1965.

ISOTOPE EXCHANGES 1963-70  CSAC 113.4.86/D.183-D.187  [n.d.]

ISOTOPE EXCHANGES 1963-70  CSAC 113.4.86/D.183  1963-1965

Contents:
Notes, drafts, references, various dates 1963-65. Includes brief notes for 'Houston lecture' dated January 1965.

ISOTOPE EXCHANGES 1963-70  CSAC 113.4.86/D.184  1969, nd

Contents:
Similar material, 1969 and undated.

ISOTOPE EXCHANGES 1963-70  CSAC 113.4.86/D.185  n.d

Contents:
Notes for publication and paper.
Includes ms. notes for 'Wirtheimer Paper' on isotope exchanges, and typescript 'Discussion of paper by Robert Pitts', n.d.
Also included here are copies of Krebs's papers Bibliog. 229, 233.
In original folder labelled 'Wirtheimer'.

ISOTOPE EXCHANGES 1963-70  CSAC 113.4.86/D.186  1969-1970

Contents:
Correspondence with colleagues re research and analyses.
Ryman, B.E. 1969-70
Landau, B.R. 1969
In original folder labelled 'Isotope Exchanges'.

ISOTOPE EXCHANGES 1963-70  CSAC 113.4.86/D.187  n.d

Contents:
Background material.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.188-D.205  [n.d.]


Related information: See also CSAC 113.4.86/D.534-CSAC 113.4.86/F.539.

Contents:
The earliest notes and drafts date from the 1960s (D.188, D.189) but the bulk of the material dates from 1970 onward. An important event was the Alfred Benzon Symposium VI on 'Regulation of hepatic metabolism' at which Krebs chaired a session and gave a paper. D.H. Williamson also gave a paper and two collaborative papers (Bibliog. 332, 333) were published in the Proceedings. Krebs continued to work on isolated liver cells until shortly before his death (see CSAC 113.4.86/D.513, CSAC 113.4.86/D.514).

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.188  1963

Contents:
Notes, drafts, data, mainly by Krebs, a few by Eggleston, on 'Cellularity determination', 1963.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.189  1966-1967

Contents:
Notes, drafts, research ideas and narratives on liver permeability, various dates 1966-67. With original folder labelled 'Liver permeability'.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.190  1970

Contents:
Brief notes and references, 1970.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.191  1972

Contents:
Notes and drafts, 1972.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.192  1973

Contents:
Extensive notes and drafts, 1973. Includes brief correspondence forwarding results.

[no title or date]  CSAC 113.4.86/D.193-D.195

Contents:
Experimental data, results, calculations, by Krebs and others, mainly on the 'Iysine effect', probably for paper at Benzon Symposium (Bibliog. 332).

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.193  1972

Contents:
November-December 1972. In original folder labelled 'Early Iysine exp. Nov-Dec 1972'.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.194  1973

Contents:
January 1973.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.195  1973

Contents:
April 1973. In original folder labelled 'Copenhagen Material'.

[no title or date]  CSAC 113.4.86/D.196-D.199

Contents:
Material on the preparation and use of isolated liver cells as experimental material, probably for paper at Benzon Symposium (Bibliog. 333).

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.196  1973

Contents:
Krebs's notes and drafts, some dated January 1973.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.197  1973

Contents:
Continuing notes and drafts, various dates March-September 1973.
Includes sketches and diagrams for equipment, and photographs.
In original folder labelled 'Isolated liver cells paper'.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.198  n.d

Contents:
Miscellaneous drafts, tables, figures, etc. for papers on isolated liver cells, n.d.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.199  1973,1974

Contents:
Photographs of liver cells, December 1973 and January 1974 (the latter with identifications and comments by Krebs on verso).

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.200  1975-1977

Contents:
Continuing notes and drafts by Krebs, various dates, August 1975-April 1977. Draft of February 1977 is headed 'Material for Paris Talk'.

[no title]  CSAC 113.4.86/D.201-D.203  1972-1973

Contents:
Correspondence with colleagues and information on isolated liver cells, 1972-73.

[no title or date]  CSAC 113.4.86/D.201, D.202

Contents:
Berry, M.N. (a principal collaborator in the use and preparation of isolated liver cells). Includes some data and drafts. Two folders as follows:

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.201  October 1972-April 1973

Contents:
Papers

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.202  June-August 1973

Contents:
Includes drafts for papers on preparation techniques, and comments by Berry on draft version of Bibliog 333, with Krebs's marginal comments.

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.203  1972, 1973

Contents:
Cohen, P.P. 1972
Francis, M. 1973
Jones, M.E. 1972
Ontko, J.A. 1973
Raijman, L. 1972
Krebs's carbon only
Schreiber, G. 1972

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.204  1973

Contents:
Programme and List of Participants for the Alfred Benzon Symposium VI on 'Regulation of Hepatic Metabolism', Copenhagen 20-24 May 1973.
Also included here are offprints of publications by Krebs et al (Bibliog. 321, 332, 333).

ISOLATED LIVER CELLS 1963-77  CSAC 113.4.86/D.205  n.d

Contents:
Background material, some annotated.

ASPARTATE c.1964  CSAC 113.4.86/D.206  [n.d.]

ASPARTATE C.1964  [no ref. or date]

Contents:
Notes and tables on 'Some effects of aspartate... on rat-brain cortex slices', prepared by G. Massieu during his period of work in Krebs's laboratory.

RESEARCH PROBLEMS 1964-67  CSAC 113.4.86/D.207  [n.d.]

RESEARCH PROBLEMS  [no ref.]  1964-1967

Contents:
Drafts and notes, most headed 'Experiments to be done', 'Problems for investigation', etc., and some with names or initials of research workers allocated to specific projects. Various dates, April 1964-July 1965.
The last note is headed 'Reg' (Hems) and includes, as well as experiments to be undertaken, the instruction 'Arrange for the transport of equipment from South Parks Road to the Radcliffe' (1967).

DRUG-INDUCED DIABETES 1965  CSAC 113.4.86/D.208  [n.d.]

DRUG-INDUCED DIABETES  [no ref. or date]

Contents:
Mainly correspondence with pharmaceutical firms and suppliers, and a little background material, on drug-induced diabetes with special reference to diuretics of the benzthiadiazine series.

CALORIC HOMEOSTASIS 1965  CSAC 113.4.86/D.209  [n.d.]

CALORIC HOMEOSTASIS  [no ref. or date]

Contents:
Brief ms. notes and annotated printed matter, kept in separate folder so inscribed by Krebs.

ALANINE 1965-73  CSAC 113.4.86/D.210-D.222  [n.d.]

Contents:
The material relates to publications in 1966 with B.M. Notton and R. Hems (Bibliog. 235) and in 1973 with R. Hems and P. Lund (Bibliog. 322, 323). Most of the original folders were labelled 'Alanine' or 'Alanine dehydrogenase'.

ALANINE 1965-73  CSAC 113.4.86/D.210  1965, nd

Contents:
Shorter notes and drafts, 1965, and undated, in various hands including Krebs, B.M. Notton and others. Also included is reprint of Bibliog. 235.

ALANINE 1965-73  CSAC 113.4.86/D.211  1967

Contents:
Notes and drafts 1967. Includes draft dated March 1967 for a proposed paper by Krebs, B.M. Notton and M. Stubbs on 'Stimulation of gluconeogenesis from alanine by phlorrhizin treatment in mouse kidney'. Not listed in the Bibliography.

ALANINE 1965-7  CSAC 113.4.86/D.212  1968

Contents:
Brief notes, tables for paper, 1968.

ALANINE 1965-7  CSAC 113.4.86/D.213  1970

Contents:
Notes, drafts, correspondence re supply and culture of Bacillus cereus and Bacillus subtilis for work on alanine dehydrogenase, April-July 1970. Includes reports on cultures processed at Imperial College, London, and at Microbial Research Establishment.

ALANINE 1965-7  CSAC 113.4.86/D.214  1970

Contents:
Continuing notes and drafts, May-December 1970.

ALANINE 1965-7  CSAC 113.4.86/D.215  1971

Contents:
Continuing notes and drafts, 'discussions with Reg (Hems) and Pat (Lund)'. Includes 10pp. heavily-corrected draft 'For Biochem. J.' dated 21 May. Various dates, January-October 1971.

ALANINE 1965-7  CSAC 113.4.86/D.216  1972-1973

Contents:
Continuing notes and drafts, May-September 1972, and January 1973.

ALANINE 1965-7  CSAC 113.4.86/D.217  n.d

Contents:
Undated ms. notes and drafts.

ALANINE 1965-7  CSAC 113.4.86/D.218  n.d

Contents:
Results, tabulated data, etc., some by Hems and Lund, most annotated by Krebs.

ALANINE 1965-7  CSAC 113.4.86/D.219  n.d

Contents:
'Accumulation of amino acids by the perfused rat liver in the presence of ethanol'.
Heavily-corrected ms. and typescript draft with a ms. note 'Draft for final copy for B.J.' (Bibliog. 322)

ALANINE 1965-7  CSAC 113.4.86/D.220  n.d

Contents:
'Regulatory mechanisms in the synthesis of urea'
Heavily-corrected ms. and typescript draft for paper by Krebs, Hems and Lund (Bibliog. 323)

ALANINE 1965-7  CSAC 113.4.86/D.221  n.d

Contents:
Miscellaneous drafts for lectures and papers, kept with above.

ALANINE 1965-7  CSAC 113.4.86/D.222  n.d

Contents:
Background material, bibliographical references.

REDOX STATE 1965-76  CSAC 113.4.86/D.223-D.238  [n.d.]

Contents:
Contents of a box labelled 'Redox State / Wilson et al. / Marion et al'. The reference is to Bibliog. 328, but Krebs lectured widely and published many collaborative papers on the redox state, several of which are referred to or included.
Notes and data

[no title or date]  CSAC 113.4.86/D.223-D.226

Contents:
Notes, drafts, experimental results, etc. for work with T. Gascoyne on rat liver homogenates (Bibliog. 260), by Krebs and Gascoyne, 1966-67.

REDOX STATE 1965-76  CSAC 113.4.86/D.223  1966

Contents:
Notes, drafts, results, comments by Krebs. Various dates, April-October 1966.

REDOX STATE 1965-76  CSAC 113.4.86/D.224  1967

Contents:
Similar material, February-July 1967 and undated.

REDOX STATE 1965-76  CSAC 113.4.86/D.225  1967

Contents:
Experimental data by Gascoyne, most with comments by Krebs, January-April 1967.

REDOX STATE 1965-76  CSAC 113.4.86/D.226  n.d

Contents:
'The redox state of the nicotinamide-adenine dinucleotides in rat liver homogenates'
Heavily-corrected ms. and typescript draft (Bibliog. 260).

[no title or date]  CSAC 113.4.86/D.227-D.229

Contents:
Notes, drafts, correspondence, etc. relating to collaborative paper published in Biochem. J. (Bibliog. 328).
Notes, drafts, ideas by Krebs.
Three folders as follows:

REDOX STATE 1965-76  CSAC 113.4.86/D.227  1965, 1966

Contents:
Papers

REDOX STATE 1965-76  CSAC 113.4.86/D.228  1969-73

Contents:
Papers

REDOX STATE 1965-76  CSAC 113.4.86/D.229  Undated

Contents:
Papers

REDOX STATE 1965-76  CSAC 113.4.86/D.230  1971

Contents:
Correspondence with colleagues and collaborators
Harris, E.J.
Includes related draft papers and printed matter.

REDOX STATE 1965-76  CSAC 113.4.86/D.231  1973-74

Contents:
Correspondence with colleagues and collaborators
Erecinska, M.

REDOX STATE 1965-76  CSAC 113.4.86/D.232  1975

Contents:
Correspondence with colleagues and collaborators
Tager, J.M.

REDOX STATE 1965-76  [no ref.]  1975

Contents:
Correspondence with colleagues and collaborators
Wilson, D.F.
Includes related printed matter.

REDOX STATE 1965-76  CSAC 113.4.86/D.233  1976

Contents:
Correspondence with colleagues and collaborators
Notes of discussions with collaborators, 1976. Note on 'Wilson's results'.

REDOX STATE 1965-76  CSAC 113.4.86/D.234  n.d

Contents:
Publications
Multiple drafts (all with variants) and comments, for paper (Bibliog. 328) under its original title 'Thermodynamic Relationships between the Oxidation-Reduction reactions and the ATP synthesis in suspensions of isolated liver cells'.
In Krebs's folder labelled 'Dave, Maria et al'.

REDOX STATE 1965-76  CSAC 113.4.86/D.235  n.d

Contents:
Publications
Earlier drafts for sections of paper, figures, etc.

REDOX STATE 1965-76  CSAC 113.4.86/D.236  n.d


Related information: See CSAC 113.4.86/D.307.

Contents:
Publications
Typescript draft for paper with M. Stubbs, titled 'Effect of uncouplers of oxidative phosphorylation on the redox-state of the hepatic nicotinamide adenine dinucleotides', with ms. note 'p.15-16 missing'.

REDOX STATE 1965-76  CSAC 113.4.86/D.237  n.d

Contents:
Publications
Offprints of some of Krebs's publications on the topic (Bibliog. 260, 268, 284, 328), kept with material.

REDOX STATE 1965-76  CSAC 113.4.86/D.238  n.d

Contents:
Publications
Background material, some annotated.

INTRACELLULAR pH 1966-71  CSAC 113.4.86/D.239, D.240  [n.d.]

INTRACELLULAR pH 1966-71  CSAC 113.4.86/D.239  1966-1971

Contents:
Notes, drafts, notes on the literature, of discussions. Various dates, 1966-71.
There is a fairly substantial draft, with tables and references, apparently for a proposed paper (3 November 1970) and also of 'Discussion with Roughton' (24 November 1970).
In Krebs's original folder.

INTRACELLULAR pH 1966-71  CSAC 113.4.86/D.240  n.d

Contents:
Printed matter, bibliographical references, some annotated.

ADIPOSE TISSUE 1967  CSAC 113.4.86/D.241  [n.d.]

ADIPOSE TISSUE  [no ref.]  1967

Contents:
Drafts, notes, correspondence, experimental data by L.V. Eggleston. The work arises mainly from articles submitted to Krebs for comment by B.B.A., Biochem. J., and includes correspondence with authors. January-April 1967.
In Krebs's original folder.

ROTENONE AND KETOSIS 1967  CSAC 113.4.86/D.242  [n.d.]

ROTENONE AND KETOSIS  [no ref. or date]

Contents:
Notes and drafts on the ketogenic effects of amytal and rotenone, with a ms. note 'Further Work on Rotenone and Ketosis'.

NUTRIENTS c.1967  CSAC 113.4.86/D.243  [n.d.]

NUTRIENTS  [no ref.]  1967

Contents:
Miscellaneous typescript and ms. tables, drafts, etc. mainly on growth rates and nutrients.
Also includes note of 'Discussions with R.A. Freedland', July 1967, on his proposed research on urea synthesis under different nutritional conditions.

CARNITINE  CSAC 113.4.86/D.244  1967, 1969

CARNITINE  [no ref. or date]

Contents:
Notes and drafts on metabolic effects of carnitine.

HEPATOTOXIC AGENTS  CSAC 113.4.86/D.245  1967-68

HEPATOTOXIC AGENTS  [no ref. or date]

Contents:
Notes, drafts, correspondence, and a little annotated printed matter, on the toxic effects of pyrrolizidine alkaloids.
In Krebs's original folder.

HUMAN LIVER DATA  CSAC 113.4.86/D.246  1967-68

HUMAN LIVER DATA  [no ref. or date]

Contents:
Data, notes, correspondence, related printed matter, on various enzyme levels in human liver.
In Krebs's original folder.

KETOGENESIS REGULATION OF TCA CYCLE  CSAC 113.4.86/D.247-D.249  1968

Contents:
Contents of a folder so inscribed.
Notes, drafts, data, correspondence, relating to work with W. Feldheim at Oxford.

KETOGENESIS REGULATION OF TCA CYCLE  CSAC 113.4.86/D.247  1968

Contents:
Notes, drafts, summary of Feldheim's research, notes for discussion etc., by Krebs, 1968.

KETOGENESIS REGULATION OF TCA CYCLE  CSAC 113.4.86/D.248  n.d

Contents:
Notes, experimental results, tabulated data, by Feldheim, with many annotations and revisions by Krebs.
In original folder.

KETOGENESIS REGULATION OF TCA CYCLE  CSAC 113.4.86/D.249  n.d

Contents:
Correspondence with Feldheim, draft of paper and tables.

EXTRAHEPATIC KETOGENESIS  CSAC 113.4.86/D.250  1968-69

EXTRAHEPATIC KETOGENESIS  [no ref. or date]

Contents:
Notes, drafts, ideas for experiments, several in bundles addressed to 'Len' (Eggleston), and including results, tables and drafts by Eggleston on 'Ketone body synthesis in rat heart homogenate'.
In Krebs's original folder.

ALCOHOL IN ANIMALS  CSAC 113.4.86/D.251-D.253  1968-70

Contents:
Contents of a folder so inscribed, perhaps related to collaborative paper with J.R. Perkins (Bibliog. 287). Krebs also gave a short broadcast talk on the subject in December 1969. 1969

ALCOHOL IN ANIMALS  CSAC 113.4.86/D.251  1968-70

Contents:
Notes and drafts on 'Rumen', 'Alcohol production by fauna', etc., 'Table of Contents' for proposed paper, miscellaneous information, press-cuttings, etc.; various dates

ALCOHOL IN ANIMALS  CSAC 113.4.86/D.252  December 1969


Related information: See also CSAC 113.4.86/H.280.

Contents:
Draft material for 'unrehearsed interview' for broadcast on 'The Living World', 6pp.

ALCOHOL IN ANIMALS  CSAC 113.4.86/D.253  1969

Contents:
Correspondence, requests for information on intoxication in animals

HOMEOSTASIS  CSAC 113.4.86/D.254  1968-71

HOMEOTASIS  [no ref. or date]

Contents:
Notes and drafts, most headed 'Caloric homeostasis' and dated May 1968 but includes some experimental data by L.V. Eggleston 1971. Includes 9pp. draft summary of research on subject, 1p. list of 'Matters which should be included in the paper', and brief correspondence.
Krebs published a collaborative paper on the subject in 1971 (Bibliog. 305).

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.255-D.261  1968-77

Contents:
Krebs's research notes and data begin in 1968, but the bulk of the material is correspondence and drafts exchanged with E. Fellenius who worked in Krebs's laboratory on the subject, April-August 1969 and for shorter periods subsequently.

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.255  1968-1969, 1977

Contents:
Notes and drafts by Krebs, data and results by L.V. Eggleston and R. Hems, various dates 1968-69, 1977.

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.256  1968-1969

Contents:
Correspondence with colleagues, 1968-69.

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.257  1969

Contents:
Correspondence re visit by Fellenius, 1969. Includes arrangements, statement of proposed research programme.

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.258  1970

Contents:
Correspondence with Fellenius, 1970.
Includes results, discussions on research, etc.

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.260  1971-1972

Contents:
Correspondence, 1971-72
Includes arrangements for visit by Fellenius, etc. Krebs's note of 31 November explains why he felt unable to sign as co-author of paper by Fellenius and K.-H. Kiessling.

METABOLISM OF ACETALDEHYDE  CSAC 113.4.86/D.261  1971

Contents:
Draft paper, sent to Krebs by Fellenius, March 1971.

RATE CONTROL OF TCA CYCLE  CSAC 113.4.86/D.262-D.266  1968-69

RATE CONTROL OF TCA CYCLE  CSAC 113.4.86/D.262  1968-1969

Contents:
Notes and drafts, various dates November 1968-November 1969. Several are headed 'Indianapolis' and the work relates to the lecture Krebs gave on 'Rate control of the tricarboxylic acid cycle' (Bibliog. 286).
In Krebs's original folder.

RATE CONTROL OF TCA CYCLE  CSAC 113.4.86/D.263  n.d

Contents:
Undated notes and drafts, some headed 'Indianapolis' or referring to preparations for the lecture. Includes draft 'Comments on Indianapolis lecture' and Krebs's correspondence requesting information.

RATE CONTROL OF TCA CYCLE  CSAC 113.4.86/D.264  n.d

Contents:
Draft for lecture, 15pp. typescript and ms. (lacks p.1) with an extra ms. page of concluding notes ending 'thank you for your endurance after two very arduous working days'. No date or place.

RATE CONTROL OF TCA CYCLE  CSAC 113.4.86/D.265  1969

Contents:
17pp. typescript and ms. draft lecture, headed Bristol March 1969'.

RATE CONTROL OF TCA CYCLE  CSAC 113.4.86/D.266  n.d

Contents:
Background material, some annotated.

METABOLISM OF WORKING HEART  CSAC 113.4.86/D.267-D.271  1969-72

Contents:
Notes, drafts, data, correspondence relating to collaborative work on the metabolism of working and non-working heart, with L.H. Opie, K.R.L. Mansford, P. Owen, R. Hems, M. Spry. The various types of material are so closely interlinked that they are presented as a simple chronological sequence with no attempt at separation.

METABOLISM OF WORKING HEART  CSAC 113.4.86/D.267  June-December 1969

Contents:
Papers

METABOLISM OF WORKING HEART  CSAC 113.4.86/D.268  1970

Contents:
Papers

METABOLISM OF WORKING HEART  CSAC 113.4.86/D.269  January-June 1971

Contents:
Papers

METABOLISM OF WORKING HEART  CSAC 113.4.86/D.270  April-May 1972

Contents:
Papers

METABOLISM OF WORKING HEART  CSAC 113.4.86/D.271  n.d

Contents:
Undated notes, background material, bibliographical references. Includes 4pp. typescript note on 'Rate control of tricarboxylic acid cycle' and a proof with ms. corrections of Krebs's paper on the subject (Bibliog. 286).

MITOCHONDRIA  CSAC 113.4.86/D.272-D.274  1969-71

Contents:
Research notes, correspondence, drafts, etc., mainly exchanged with E.J. Harris.

MITOCHONDRIA  CSAC 113.4.86/D.272  1969-71

Contents:
Includes an early note by Krebs on 'Substrate competition' dated May 1962.

MITOCHONDRIA  CSAC 113.4.86/D.273  1971

Contents:
Papers

MITOCHONDRIA  CSAC 113.4.86/D.274  n.d

Contents:
Extensive background material, some annotated.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.275-D.288  1969-75


Related information: See also CSAC 113.4.86/D.391.

Contents:
Krebs lectured regularly on disorders or special aspects of metabolism to students in the Oxford Medical School. One of these lectures, on Sir Archibald Garrod, the history of the Whitley Professorship of Biochemistry, and the formation of the concept of inborn errors of metabolism, was published in 1970 (Bibliog. 291). Notes and drafts for these lectures are at CSAC 113.4.86/D.275-CSAC 113.4.86/D.279.
In 1970 a case was notified to Krebs of the specific metabolic disorders of hyperammonaemia and ornithine transcarbamylase deficiency. He studied the case in collaboration with medical colleagues on the staff of the United Oxford Hospitals (as they were then known) and prepared a paper for publication in Archives of Disease in Childhood. This material is at CSAC 113.4.86/D.286. The paper was not published.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.275  1969, 1970

Contents:
Variously paginated notes and drafts, some dated 1969, 1970, for lecture on Garrod and the history of inborn errors of metabolism (Bibliog. 291).

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.276  1971

Contents:
Notes, drafts, time-tabling, material for three 'Bridge Course' lectures on 'Special Aspects of Diseases of Metabolism', 15-17 November 1971.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.277  1973

Contents:
Notes and drafts for 'Bridge Course' lectures on inborn errors, March 1973.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.278  1973, 1974, 1975

Contents:
Brief notes for 'Bridge Course' lectures, December 1973, and short introduction for December 1974 and February 1975.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.279  1972, 1975

Contents:
Brief correspondence, lecture schedules and notes, 1972, 1975.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.280  1970-1972

Contents:
Hyperammonaemia case
Correspondence with colleagues on diagnosis, treatment, arrangement to demonstrate, 1970-72.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.281  1970-1971

Contents:
Hyperammonaemia case
Data and notes, by Krebs and others, 1970-71.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.282  1973-1975

Contents:
Hyperammonaemia case
Krebs's notes and drafts. Mainly 1973-75, but includes some earlier notes (1963) on dietary treatment of ammonia intoxication.

[no title or date]  CSAC 113.4.86/D.283-D.286

Contents:
Variously paginated notes and drafts for lectures and publication on the case.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.283  1971

Contents:
Notes for lecture or demonstration, various dates January-February 1971 (in Krebs's order, not chronological). The note for 29 January describes his personal interest in the case as a link with his experience in 1931 'as a clinician at Freiburg University with full responsibility for patients'.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.284  1971

Contents:
Miscellaneous notes, some dated July 1971 and headed 'Ciba'.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.285  1972-1973

Contents:
Shorter drafts, 1972, 1973, and undated.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.286  1974, 1975

Contents:
Various drafts, in typescript and ms., some by Krebs or with ms. corrections by him and by others, some dated 1974, 1975; with brief correspondence re submission of paper to Arch. Dis. Childh.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.287  n.d

Contents:
Bibliographical references. In Krebs's folder inscribed 'Literature. Inborn Errors'.

INBORN ERRORS OF METABOLISM / HYPERAMMONAEMIA / ORNITHINE TRANSCARBAMYLASE DEFICIENCY  CSAC 113.4.86/D.288  n.d

Contents:
Extensive background material, some annotated by Krebs.

GLUCOSE FFA CYCLE  CSAC 113.4.86/D.289  1970

Contents:
Brief notes, ideas for research and discussion on 'is there a glucose home ostasis separable from caloric homeostasis?', correspondence. Various dates, October-December 1970. In Krebs's original folder.

HORMONES AND GLUCONEOGENESIS  CSAC 113.4.86/D.290  1970

HORMONES AND GLUCONEOGENESIS  [no ref. or date]

Contents:
Brief notes and drafts, December 1970. In Krebs's original folder.

INTERMEDIATE LIVER METABOLISM  CSAC 113.4.86/D.291  1970-72

INTERMEDIATE LIVER METABOLISM  [no ref. or date]

Contents:
Notes, drafts, data and results by R. Hems, with Krebs's annotations, various dates, December 1970, July 1972. In Krebs's original folder inscribed 'Sauer', the work being developed from a paper by F. Sauer et al published in Eur. J. Biochem. 17, 1970, a copy of which is included.

PASTEUR EFFECT  CSAC 113.4.86/D.292, D.293  1970-71

PASTEUR EFFECT  CSAC 113.4.86/D.292  1970-1971, 1972

Contents:
Notes and drafts, various dates, October 1970-December 1971. In Krebs's original folder inscribed 'Pasteur Draft' and perhaps related to the paper he published in 1972 on 'The Pasteur effect and the relations between respiration and fermentation' (Bibliog. 316, German version Bibliog. 312).

PASTEUR EFFECT  CSAC 113.4.86/D.293  n.d

Contents:
Background material, almost all annotated by Krebs.

AMINOTRANSFERASES  CSAC 113.4.86/D.294-D.304  1970-72

Contents:
The work was conducted in collaboration with L.V. Eggleston. Two draft papers were in preparation (CSAC 113.4.86/D.302, CSAC 113.4.86/D.303) and Krebs also used the material for one of his lectures at Indianapolis (CSAC 113.4.86/D.298-CSAC 113.4.86/D.301).

AMINOTRANSFERASES  CSAC 113.4.86/D.294  1970

Contents:
Discussion notes and correspondence with M.F. Utter, 1970. Included here are some earlier notes (October-November 1968) of discussions with Utter on pyruvate carboxylase.

AMINOTRANSFERASES  CSAC 113.4.86/D.295  1970

Contents:
Drafts, data, results, narratives, mainly by Krebs but some by Eggleston, January-November 1970.

AMINOTRANSFERASES  CSAC 113.4.86/D.296  1971, 1972

Contents:
Similar material, but including many results, drafts, tables, etc. by Eggleston, and mainly on Iysine metabolism, January-September 1971, April 1972. In Krebs's original folder inscribed 'Rat Tissue Aminotransferases'.

AMINOTRANSFERASES  CSAC 113.4.86/D.297  n.d

Contents:
Miscellaneous shorter undated notes and drafts.

[no title or date]  CSAC 113.4.86/D.298-D.301

Contents:
Drafts for lectures and papers
Ms. and typescript drafts for a paper, to be given at Indianapolis.

AMINOTRANSFERASES  CSAC 113.4.86/D.298  n.d

Contents:
9pp. ms., headed 'Indianapolis. Amino acid'.

AMINOTRANSFERASES  CSAC 113.4.86/D.299  1970

Contents:
6pp. typescript and ms. 'Regulation of the supply of essential amino acids', dated 22 June 1970.

AMINOTRANSFERASES  CSAC 113.4.86/D.300  n.d

Contents:
7pp. ms. 'Organ Distribution of Aminotransferases', n.d.

AMINOTRANSFERASES  CSAC 113.4.86/D.301  n.d

Contents:
20pp. typescript 'Regulatory Mechanisms in Mammalian Amino Acid Metabolism' (slide lecture).

[no title or date]  CSAC 113.4.86/D.302, D.303

Contents:
Drafts for two papers by Eggleston and Krebs.

AMINOTRANSFERASES  CSAC 113.4.86/D.302  1972

Contents:
'Paper A. Induction and depression of rat liver aminotransferases', 12 April 1972.

AMINOTRANSFERASES  CSAC 113.4.86/D.303  1972

Contents:
'Paper B. Comparative activity of aminotransferases in rat and human tissue', 19 April 1972.
Both in Krebs's original folder inscribed by him with Eggleston's initials and the titles of both papers. The papers were not published, but part of the work was used in Bibliog. 310.

AMINOTRANSFERASES  CSAC 113.4.86/D.304  n.d

Contents:
Background material.

OXIDATIVE PHOSPHORYLATION  CSAC 113.4.86/D.305-D.307  1971

OXIDATIVE PHOSPHORYLATION  CSAC 113.4.86/D.305  1971

Contents:
Drafts and notes, mainly 1971.

OXIDATIVE PHOSPHORYLATION  CSAC 113.4.86/D.306  1971

Contents:
Correspondence and results from R.L. Veech, 1971.

OXIDATIVE PHOSPHORYLATION  CSAC 113.4.86/D.307  n.d


Related information: See CSAC 113.4.86/D.236.

Contents:
'Effect of uncouplers of oxidative phosphorylation on the redox-state of the hepatic nicotinamide adenine dinucleotides'.
Three drafts for a paper so titled, by Krebs and M. Stubbs, two with extensive ms. corrections mainly by Krebs, but some by M. Stubbs, and final typescript draft ready for submission. The paper was not published but some of the material was published in 1979 by M. Stubbs in Pharmac. Ther., 7, 329-350 under the title 'Inhibitors of the adenine nucleotide translocase'.

KETONE BODY METABOLISM IN DIABETES  CSAC 113.4.86/D.308, D.309  1971

Contents:
Notes, drafts, etc. arising from work on the subject by N.B. Ruderman.

KETONE BODY METABOLISM IN DIABETES  CSAC 113.4.86/D.308  1971

Contents:
Krebs's notes, points to be discussed with Ruderman, correspondence with Ruderman, 1971.

KETONE BODY METABOLISM IN DIABETES  CSAC 113.4.86/D.309  n.d

Contents:
Notes, drafts, tables, with ms. corrections by Krebs and others.

ADIPOSE TISSUE  CSAC 113.4.86/D.310  1971

ADIPOSE TISSUE  [no ref. or date]

Contents:
Notes, drafts, bibliographical references, some dated 1971; probably arising from papers submitted for publication in FEBS Letters, some of which are included in the folder.

REDOX STATE IN BACTERIA  CSAC 113.4.86/D.311-D.313  1971-72

REDOX STATE IN BACTERIA  CSAC 113.4.86/D.311  1971, 1972

Contents:
Notes and drafts, various dates, May-July 1971, and 1972. Includes brief correspondence with colleagues.

REDOX STATE IN BACTERIA  CSAC 113.4.86/D.312  n.d

Contents:
Krebs's previous publications on subject (Bibliog. 245, 276, 285).

REDOX STATE IN BACTERIA  CSAC 113.4.86/D.313  n.d

Contents:
Background material.

REVERSIBILITY OF RESPIRATORY CHAIN  CSAC 113.4.86/D.314-D.316  1971-74

Contents:
Contents of a folder so inscribed.

REVERSIBILITY OF RESPIRATORY CHAIN  CSAC 113.4.86/D.314  1971, 1974

Contents:
Notes and drafts, some dated 1971, 1974.

REVERSIBILITY OF RESPIRATORY CHAIN  CSAC 113.4.86/D.315  1973, nd

Contents:
Draft for paper 'Can the mitochondrial respiratory chain be considered as a system which approaches equilibrium', not by Krebs, but with ms. comments and corrections by him. pp.25-65 with two appendices. Some pages dated 1973. Perhaps related to Bibliog. 328.

REVERSIBILITY OF RESPIRATORY CHAIN  CSAC 113.4.86/D.316  1971, 1973

Contents:
Correspondence and data from colleagues.
R.L. Veech, 1971
D.F. Wilson, 1973

ALCOHOL METABOLISM IN LIVER  CSAC 113.4.86/D.317  1971-74

ALCOHOL METABOLISM IN LIVER  [no ref. or date]

Contents:
Shorter drafts and notes, some dated 1971, 1974.

RETINAL METABOLISM  CSAC 113.4.86/D.318-D.329  1971-72

RETINAL METABOLISM  CSAC 113.4.86/D.318  n.d

Contents:
Notes and drafts
Stapled folder of notes, bibliographical references, notes on the literature, 3pp. ms. outline for research project on retinal metabolism. Some by Krebs but mainly in another hand, perhaps R.A. Hawkins.

RETINAL METABOLISM  CSAC 113.4.86/D.319  1971-1972

Contents:
Notes and drafts
Notes, drafts, research data, tabulated results, by Krebs and by R. Hems, some dated August 1971-February 1972. In folder inscribed 'Eye Material'.

RETINAL METABOLISM  CSAC 113.4.86/D.320  1971-1972

Contents:
Notes and drafts
Similar material, for work on 'Avian (and other) Retina', instructions for collaborators, draft tables, data and results by R. Hems, etc., some dated October 1971-November 1972.

RETINAL METABOLISM  CSAC 113.4.86/D.321  n.d

Contents:
Notes and drafts
Bibliographical references and notes on the literature, by Krebs.

RETINAL METABOLISM  CSAC 113.4.86/D.322  1972

Contents:
Lectures and publications
'The Energy Metabolism of the Retina'
Drafts for a paper by Krebs and R. Hems, with R.A. Hawkins appearing as a collaborator on later versions.
3 drafts, all with different ms. corrections and additions, 11pp., 3pp. references, tables 1-12. p.1 dated February 1972. In folder inscribed 'Retina Draft'. The paper was not published.

RETINAL METABOLISM  CSAC 113.4.86/D.323  1972

Contents:
Lectures and publications
'Ultrastructure of the avian retina. An anatomical study of the retina of the domestic pigeon ...' (Bibliog. 315).
3 drafts, all with different ms. corrections and additions by Krebs. The second draft is dated February 1972; the third refers to the paper by Krebs, Hawkins and Hems, 1972 (CSAC 113.4.86/D.322 above) as 'in preparation'.

RETINAL METABOLISM  CSAC 113.4.86/D.324  n.d

Contents:
Lectures and Publications
Miscellaneous notes, slide-list, etc. for a lecture on retinal metabolism, given in various locations listed on folder (Hull, Southampton, Jerusalem, University College London, Rehovoth, Leicester, Oxford Eye Hospital).

RETINAL METABOLISM  CSAC 113.4.86/D.325  n.d

Contents:
Lectures and Publications
Miscellaneous pages for a lecture on the subject, in German.

RETINAL METABOLISM  CSAC 113.4.86/D.326  1971-1972

Contents:
Correspondence and information from colleagues.
Berman, E.R. 1971
Hawkins, R.A. 1972

RETINAL METABOLISM  CSAC 113.4.86/D.327  1972

Contents:
Correspondence and information from colleagues.
Michaelson, I.C. 1971-72
Includes Krebs's research notes and ideas, notes of discussions with Michaelson on various occasions in 1972, etc.

RETINAL METABOLISM  CSAC 113.4.86/D.328  1971

Contents:
Correspondence and information from colleagues.
Vail, W.J. 1971
Includes research notes, references, related printed matter.

RETINAL METABOLISM  CSAC 113.4.86/D.329  n.d

Contents:
Correspondence and information from colleagues.
Background material, some annotated by Krebs.

SALINE MEDIA  CSAC 113.4.86/D.330  1971, 1976

Contents:
Ms. and typescript notes and drafts, various dates, 1971, 1976.

CALORIMETRY  CSAC 113.4.86/D.331-D.341  1971-78

Contents:
Correspondence with colleagues and manufactures, notes, drafts, results, etc. on the development of microcalorimetry for biological research. The material is presented as a chronological sequence, including research papers or reports sent to Krebs, in order to preserve the various contacts, visits and inter-related projects involved in the furtherance of the research.
T.H. Benzinger, correspondence with whom from 1971 contributed to Krebs's involvement in the work, had worked in Krebs's department 1955-57. His principal collaborators at that time had been R. Hems and Kitzinger, and three papers were published in 1956 and 1959 (2).
The chief correspondents in the present sequence are:
G.T. Armstrong, National Bureau of Standards, Washington D.C.
T.H. Benzinger, National Bureau of Standards, Maryland
R.L. Berger, University of California
H.U. Bergmeyer, C.F. Boeringer GmbH, Germany
G.P. Burn, Department of Clinical Biochemistry, Radcliffe Infirmary, Oxford
K. Burton, University of Newcastle
E.J. Prosen, National Bureau of Standards, Washington D.C.

CALORIMETRY  CSAC 113.4.86/D.331  March-May 1971

Contents:
Papers

CALORIMETRY  CSAC 113.4.86/D.332  June-October 1971

Contents:
Papers

CALORIMETRY  CSAC 113.4.86/D.333  1972

Contents:
Includes arrangements for demonstrating Bureau of Standards calorimeter in Krebs's laboratory, arrangements for him to consult regularly on project at National Bureau of Standards, Washington, grant application, etc.

CALORIMETRY  CSAC 113.4.86/D.334  1973

Contents:
Correspondence, results, discussion notes, list of participants at conference on Microcalorimetric Investigations, Lund, July.

CALORIMETRY  CSAC 113.4.86/D.335  March-June 1974

Contents:
Collaborative work, discussion of results and papers, with E.J. Prosen and K. Burton.

CALORIMETRY  CSAC 113.4.86/D.336  July-December 1974

Contents:
Correspondence, notes, related printed matter.

CALORIMETRY  CSAC 113.4.86/D.337  1975-76

Contents:
Mainly Krebs's notes and drafts, some results by G.P. Bum.

CALORIMETRY  CSAC 113.4.86/D.338  1977

Contents:
Includes miscellaneous drafts for paper by Prosen on microcalorimetric studies.

CALORIMETRY  CSAC 113.4.86/D.339  1975-1978

Contents:
Reports on microcalorimetry by G.P. Burn, nos.4-9, 12-14, various dates, 1975-78.

CALORIMETRY  CSAC 113.4.86/D.340  n.d

Contents:
Correspondence with suppliers, quotations, manufactures' literature.

CALORIMETRY  CSAC 113.4.86/D.341  n.d

Contents:
Background material.

ACETYLGLUTAMATE  CSAC 113.4.86/D.342  1972

ACETYLGLUTAMATE  [no ref. or date]

Contents:
Shorter notes and drafts.

UREA CYCLE  CSAC 113.4.86/D.343  1972

UREA CYCLE  [no ref. or date]

Contents:
Miscellaneous notes and drafts, probably for lectures at Kansas City and Indianapolis; some pages dated 1972 (perhaps draft for Bibliog. 323).

AMINO ACID ANALYSES IN LIVER CELLS  CSAC 113.4.86/D.344-D.348  1972-74

Contents:
Several of Krebs's original folders on this subject are headed 'Schimassek' and refer to research findings by H. Schimassek (q.v.) which Krebs developed.

AMINO ACID ANALYSES IN LIVER CELLS  CSAC 113.4.86/D.344  1972-73

Contents:
Correspondence with colleagues

AMINO ACID ANALYSES IN LIVER CELLS  CSAC 113.4.86/D.345  1973

Contents:
Notes and research ideas

AMINO ACID ANALYSES IN LIVER CELLS  CSAC 113.4.86/D.346  1972

Contents:
Experimental data and results, mainly by R.C. Farrell, some by D. Wiggins, several annotated by Krebs or interleaved with his comments or suggestions, various dates

AMINO ACID ANALYSES IN LIVER CELLS  CSAC 113.4.86/D.347  1973-1974

Contents:
Similar material by Farrell, Wiggins and Hems, interleaved with notes by Krebs, various dates, 1973, and a little material 1974. An extensive folder.

AMINO ACID ANALYSES IN LIVER CELLS  CSAC 113.4.86/D.348  n.d

Contents:
Background material.

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.349-D.358  1972-74

Contents:
Data and drafts by Krebs and collaborators (M. Stubbs, P. Lund, D. Wiggins) on various factors in urea synthesis, leading to the chapter contributed by Krebs, Lund and Stubbs on 'Interrelations between gluconeogenesis and urea synthesis' in Gluconeogenesis (ed. R.W. Hanson and M.A. Mehlman) 1976 (Bibliog. 347).

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.349  [n.d.]

Contents:
Research data and results
'LIVER PERFUSIONS. UREA SYNTHESIS'
Folder so inscribed (in the hand of M. Stubbs). Extensive data, graphs, results, in various hands, many with annotations by Krebs. Various dates, mainly 1972, but a few 1974.

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.350  1973-1974

Contents:
Research data and results
'GLUCONEOGENESIS AND UREA SYNTHESIS. EGG WHITE DIET. MEAT DIET. NORMAL FED'
Folder so inscribed (in the hand of M. Stubbs). Similar material, 1973 and 1974

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.351  1973-1974

Contents:
Research data and results
Similar material, found as loose papers, various dates, 1973 and 1974.

GLUCONEOGENESIS AND UREA SYNTHESIS  [no ref. or date]

Contents:
Notes and drafts for paper (Bibliog. 347)
These are extensively revised and corrected, mainly by Krebs, but some by M. Stubbs, and may incorporate similar data to that above. Several have a ms. indication 'Lardy Festschrift', 'Lardy Volume', etc.

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.352  1972

Contents:
Notes and drafts for paper (Bibliog. 347)

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.353  1973

Contents:
Notes and drafts for paper (Bibliog. 347)
Notes for June-July incorporate correspondence and discussions with L. Raijman and M.E. Jones.

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.354  October 1974

Contents:
Papers

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.355  November 1974

Contents:
Papers

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.356  December 1974

Contents:
Papers

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.357  n.d

Contents:
Miscellaneous undated notes, drafts, tables, etc.

GLUCONEOGENESIS AND UREA SYNTHESIS  CSAC 113.4.86/D.358  n.d

Contents:
Background material.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.359-D.372  1972-74

Contents:
Krebs's chief collaborator in this work was L.V. Eggleston, who died in January 1974 when their collaborative paper (Bibliog. 327) was in the press. Another collaborative paper (Bibliog. 329) was published in the same year. In addition, Krebs gave several lectures and papers on the subject in Britain and abroad (see CSAC 113.4.86/D.369-CSAC 113.4.86/D.371).
The main bulk of the research notes and drafts are 1972-74, but see CSAC 113.4.86/D.359 for some of much earlier date.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.359  1949 (1p. only), 1967 (1p. only), August-December 1972

Contents:
Research notes, drafts, discussions

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.360  1973

Contents:
Papers

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.361  1974

Contents:
Papers

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.362  Undated

Contents:
Mainly by Krebs, a few by Eggleston.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.363  1972-1973

Contents:
Experimental results, data, tables, drafts, summaries, mainly by Eggleston, with comments or annotations by Krebs. Various dates, December 1972-September 1973. In Eggleston's original folder.

[no title or date]  CSAC 113.4.86/D.364, D.365

Contents:
Lectures and publications
'Regulation of the pentose phosphate cycle' (Bibliog. 327)

PENTHOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.364  n.d

Contents:
Lectures and publications
Extensive drafts by Eggleston and Krebs. In Eggleston's original folder.

PENTHOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.365  n.d

Contents:
Lectures and publications
Comments on paper, editorial correspondence with Biochem. J. re referees' comments, offprint of published paper.

[no title or date]  CSAC 113.4.86/D.366-D.368

Contents:
'The regulation of the pentose phosphate cycle in rat liver' (Bibliog. 329).
Various drafts and versions for lecture at Indianapolis, subsequently published.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.366  n.d

Contents:
Typescript and ms. draft by Krebs and Eggleston, with a ms. note 'File away 2.5.74.'

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.367  n.d

Contents:
Typescript with ms. corrections, with a ms. note 'Use this for lecture'.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.368  n.d

Contents:
Typescript with ms. corrections, with a ms. note 'Corrected copy'; list of references; proof of publication, with corrections.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.369  1974

Contents:
Symposium on Aspects of Metabolic Regulation, University of Bristol, 15 February 1974.
The Symposium was organised by P.J. Randle. Krebs gave the last paper (on 6-Phosphate Dehydrogenase) and 'concluding comments'. Folder includes correspondence with organiser, programmes, list of participants, 12pp. draft for lecture, ms. notes for concluding comments.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.370  1974

Contents:
1p. ms. notes for lecture at Madrid, 20 May 1974 (using material of Bristol lecture).
15pp. draft for lecture in German at Düsseldorf, 24 May 1974 (using material of Bibliog. 329).

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.371  n.d

Contents:
Notes for visit to Washington (not dated), including tables for lecture on pentose phosphate cycle.

PENTOSE-PHOSPHATE CYCLE  CSAC 113.4.86/D.372  [n.d.]

Contents:
Background material, bibliographical references, some annotated.

6-AMINO-NICOTINAMIDE  CSAC 113.4.86/D.373-D.378  1972-77

Contents:
Notes, drafts, data, discussion

6-AMINO-NICOTINAMIDE; Notes, drafts, data, discussions  CSAC 113.4.86/D.373  1972, 1974

Contents:
(Several arising from discussions with H. Herken).

6-AMINO-NICOTINAMIDE; Notes, drafts, data, discussions  CSAC 113.4.86/D.374  1976-77

Contents:
Includes data by D. Wiggins.

6-AMINO-NICOTINAMIDE  CSAC 113.4.86/D.375  1975-77

Contents:
Correspondence with colleagues
Harris, R.A.
Includes data, results, etc.

6-AMINO-NICOTINAMIDE  CSAC 113.4.86/D.376  1972-76

Contents:
Correspondence with colleagues
Herken, H.

6-AMINO-NICOTINAMIDE  CSAC 113.4.86/D.377  1977

Contents:
Correspondence with colleagues
Mc Lean, P.

6-AMINO-NICOTINAMIDE  CSAC 113.4.86/D.378  [n.d.]

Contents:
Correspondence with colleagues
Extensive background material, some annotated.

COMPETITION BETWEEN SHORT-AND LONG-CHAIN FATTY ACIDS IN PERFUSED RAT LIVER [1973]  CSAC 113.4.86/D.379  [n.d.]

Contents:
Report so titled, tables, etc. by J. Medina, with ms. notes by Krebs. Medina's title on the folder has been amended by Krebs to 'On competition between acetate and oleate in perfused rat liver'. n.d., but Medina worked in Krebs's laboratory in summer 1973.

SULPHONAMIDES  CSAC 113.4.86/D.380  1973-74

SULPHONAMIDES  [no ref. or date]

Contents:
Drafts, notes, data on sulphonamides and sulphanilamide. Includes experimental results by D. Wiggins with comments by Krebs. Various dates, November 1973-January 1974.

FLUOROCARBONS  CSAC 113.4.86/D.381  1973-74

FLUOROCARBONS  [no ref. or date]

Contents:
Background material only, some annotated with reference to fluorocarbons as blood substitutes.

OVER-MEDICATION  CSAC 113.4.86/D.382-D.395  1973-78

Contents:
This topic became one of Krebs's principal concerns in later life. Most of his own notes, drafts and annotations are headed 'Over-medication' but later the more technical term 'latrogenic' was used, e.g. for the section which Krebs incorporated in the Dunham Lectures (CSAC 113.4.86/D.459 et. seq.).
For additional material about Krebs's involvement see Special Commission on Internal Pollution in Section G and CSAC 113.4.86/J.599, CSAC 113.4.86/J.600.

OVER-MEDICATION  CSAC 113.4.86/D.382  1974

Contents:
Research notes and information
Notes and drafts by Krebs, various dates, 1974.

OVER-MEDICATION  CSAC 113.4.86/D.383  n.d

Contents:
Research notes and information
Undated notes, many with accompanying press-cuttings.

OVER-MEDICATION  CSAC 113.4.86/D.384  n.d

Contents:
Research notes and information
Specimens of multiple prescriptions, from Radcliffe Infirmary, Oxford.

OVER-MEDICATION  CSAC 113.4.86/D.385  1973-1978

Contents:
Research notes and information
Correspondence from colleagues forwarding information:
Clarke, C.A. 1975
Sicé, J. 1973
Smith, D.G. 1978

OVER-MEDICATION  CSAC 113.4.86/D.386  1974

Contents:
Lectures and publications
Drafts for article, variously titled 'The Dangers of Over-Medication' and 'On the Mis-Use of Drugs', and published as 'On the overuse and misuse of medication', in Executive Health, 1974 (Bibliog. 334). First draft dated 12 August, second dated 2 September 1974.

OVER-MEDICATION  CSAC 113.4.86/D.387  n.d

Contents:
Lectures and publications
Two other drafts, with different corrections and revisions.
Folder also includes copy of paper as published.

OVER-MEDICATION  CSAC 113.4.86/D.388  1973-1974

Contents:
Lectures and publications
'Abuse of Drugs (The Hidden Danger)'
Brief drafts, December 1973-January 1974, with a note 'Possible lecture subject for Indianapolis 1974'.

OVER-MEDICATION  CSAC 113.4.86/D.389  1974

Contents:
Lectures and publications
'Material used at a lecture at Hanover on 27 April 1974' (text in German).

OVER-MEDICATION  CSAC 113.4.86/D.390  n.d

Contents:
Lectures and publications
Ms. and typescript drafts for a lecture in German on over-medication. This was in fact the second of two subjects on which Krebs announced his intention to lecture. The first topic was hyperammonaemia (see below).

OVER-MEDICATION  CSAC 113.4.86/D.391  n.d

Contents:
Lectures and publications
Ms. and typescript draft for lecture in German on hyperammonaemia.

OVER-MEDICATION  CSAC 113.4.86/D.392  1974

Contents:
Lectures and publications
'Overmedication'
19pp. typescript lecture, with a note 'Philadelphia Oct. 1974, Oxford Bridge Course Dec. 1974'.

OVER-MEDICATION  CSAC 113.4.86/D.393  1975

Contents:
Lectures and publications
Drafts for talk at Oxford on overmedication, probably in Department of Clinical Pharmacology, April 1975.

OVER-MEDICATION  CSAC 113.4.86/D.394  n.d

Contents:
Lectures and publications
Miscellaneous drafts and notes for talk on carcinogenic agents, n.d.

OVER-MEDICATION  CSAC 113.4.86/D.395  n.d

1 box.

Contents:
Lectures and publications
Extensive background material.

CRASSULACEAE  CSAC 113.4.86/D.396  1974

CRASSULACEAE  [no ref. or date]

Contents:
Discussion note on possible collaborative research project with F.R. Whatley, correspondence, background material, February-April 1974.

CARNOSINE  CSAC 113.4.86/D.397  1974

CARNOSINE  [no ref. or date]

Contents:
Brief notes and background material.

SHUTTLES AND CARRIERS  CSAC 113.4.86/D.398, D.399  1974

SHUTTLES AND CARRIERS  CSAC 113.4.86/D.398  1972, 1974

Contents:
Notes and drafts on various factors in metabolic transport (malate, pyruvate, alanine, lactate, etc.), mainly January-February 1974, but includes letter from colleague on subject, 1972.

SHUTTLES AND CARRIERS  CSAC 113.4.86/D.399  [n.d.]

Contents:
Background material.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.400-D.408  1974

Contents:
Notes and drafts mainly related to work on collaborative paper by Krebs, H.F. Woods and K.G.M.M. Alberti, published under this title in the first issue of Essays Med. Biochem., 1975 (Bibliog. 337). Includes some earlier notes of the 1960s.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.400  1963, 1964, 1968

Contents:
Shorter notes and drafts 1963, 1964, 1968.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.401  1974

Contents:
Extensive drafts and notes for 'essay', by Krebs or by collaborators, with extensive revisions by Krebs, January-February 1974.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.402  1974

Contents:
Continuing drafts, March-April 1974.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.403  1974

Contents:
Continuing drafts, July-September 1974.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.404  n.d

Contents:
Undated notes and drafts.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.405  n.d

Contents:
Extensive bibliographical references.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.406  n.d

Contents:
Final draft for 'essay'. Typescript with very extensive ms. corrections.

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.407  1974

Contents:
Drafts for letter to The Lancet, July 1974, arising from a letter (June 1974) by R.A. Kreisberg (also referred to in 'essay').
The letter was not published (perhaps not sent).

HYPERLACTATAEMIA AND LACTIC ACIDOSIS  CSAC 113.4.86/D.408  n.d

Contents:
Background material, some annotated.

RENAL AMMONIA  CSAC 113.4.86/D.409-D.414  1974

Contents:
Notes, drafts, etc. mainly related to collaborative work with P. Vinay (q.v.) who worked in Krebs's laboratory 1973-75 (Bibliog. 338).

RENAL AMMONIA  CSAC 113.4.86/D.409  1974

Contents:
Notes and drafts, by Krebs and by Vinay, March-June 1974. Note of 24 June is headed 'Notes on Pitts conference'. Notes of 28 June are for 'Seminar - June 29' (probably at Oxford).

RENAL AMMONIA  CSAC 113.4.86/D.410  1974

Contents:
Continuing notes and drafts, July 1974.

RENAL AMMONIA  CSAC 113.4.86/D.411  n.d

Contents:
Undated notes by Krebs and by Vinay.

RENAL AMMONIA  CSAC 113.4.86/D.412  1974

Contents:
Typescript and ms. draft for lecture on subject, referring to work with Vinay and also to work of R. Pitts and perhaps related to Pitts Symposium, June 1974. For Pitts symposium see F.259, F.260.

RENAL AMMONIA  CSAC 113.4.86/D.413  n.d

Contents:
'Regulation of Renal Ammonia Production'. Typescript and ms. drafts for Bibliog. 338.

RENAL AMMONIA  CSAC 113.4.86/D.414  n.d

Contents:
Background material. Includes copy of Bibliog. 233.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.415-D.435  1974-78

Contents:
Material on these inter-related topics was kept together by Krebs in one box so inscribed. He published several collaborative papers (Bibliog. 348, 350, 360) and the work is mentioned by Kornberg and Williamson as among the most important of his later research (Memoir, p. 377).

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.415  1975

Contents:
Notes and drafts
Indexed bundle of ms. and typescript notes and drafts, discussions with colleagues, research ideas and results, etc. Various dates, March-November 1975.
With typescript index (12 items, of which nos. 6-10 are missing).
This is material similar to that kept as 'Indexed notes and memoranda' at D.46-D.100, but here kept with other loose pages of drafts and notes.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.416  1974-1975

Contents:
Notes and drafts
Ms. and typescript notes and drafts, February 1974, January-June 1975.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.417  1975

Contents:
Notes and drafts
Continuing notes and drafts, July-December 1975.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.418  1976

Contents:
Notes and drafts
Continuing notes and drafts, 1976.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.419, D.420  n.d

Two folders.

Contents:
Notes and drafts
Undated notes and drafts.

FOLATE / B12 / METHIONINE / HISTIDINE; Notes and drafts  CSAC 113.4.86/D.421, D.422  [n.d.]

Contents:
Notes and drafts, mainly on histidine, related to collaborative paper with R. Hems (Bibliog. 348).

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.421  1974

Contents:
Experimental data and results, by Krebs and collaborators, various dates, January 1974.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.422  1972-1976

Contents:
Extensive notes, drafts, tables, etc. by Krebs and Hems, some dated 1975, 1976, but also including earlier notes of discussions on histidine with N. Cornell, 1972 and 1974. Note of 23 January 1975 is on FIGLU as a substrate for glutamic dehydrogenase, later developed in Bibliog. 360.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.423  1975, 1978

Contents:
Correspondence with colleagues
Scrutton, M.C.
Correspondence 1978 includes arrangements and programme for Symposium and Workshop on 'Gluconeogenesis and Its Regulation', Oxford, September 1978. Krebs was Chairman, gave the 'Opening Remarks' and participated in the final general discussion. There are ms. and typescript drafts dated January 1978 headed 'Notes on the history of regulation of enzyme activity' perhaps intended for delivery at the Symposium (see also D.433).
Also included are drafts of papers by Scrutton on histidine, with comments by Krebs.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.424  1976

Contents:
Correspondence with colleagues
Sellinger, O.Z.
Includes related printed matter.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.425  1975-76

Contents:
Correspondence with colleagues
Smith, R.M.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.426  1976

Contents:
Lectures and publications
'The Regulation of Folate and Methionine Metabolism', by Krebs, Hems and B. Tyler. Heavily-corrected typescript and ms. draft for Bibliog. 350 dated January 1976.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.427  n.d

Contents:
Lectures and publications
Offprints of Krebs's publications, Bibliog. 348, 350 (annotated and revised).

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.428  n.d

Contents:
Lectures and publications
'Draft for the Lancet'
10pp. draft for article on cobalamine (vitamin B12) deficiency. The article was not published and was perhaps not sent.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.429  1976

Contents:
Lectures and publications
'Regulation of folate and methionine metabolism'. Ms. and typescript (incomplete) draft for lecture, 5 January 1976.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.430  1976

Contents:
Lectures and publications
'Univ. College Chem. & Physical Soc'
4pp. ms. notes for lecture, 27 January 1976.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.431  1976

Contents:
Lectures and publications
'Histidine metabolism and methionine'
Typescript and ms. draft with a ms. note 'Philadelphia', 14 September 1976.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.432  1977

Contents:
Lectures and publications
'History of the Study of Regulation of Metabolism'
1p. ms. notes only, December 1977.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.433  1978

Contents:
Lectures and publications
Miscellaneous notes, April 1978, on control mechanisms at enzyme level, perhaps intended for symposium organised by M.C. Scrutton.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.434  n.d

Contents:
Lectures and publications
Bibliographical references on folate and methionine.

FOLATE / B12 / METHIONINE / HISTIDINE  CSAC 113.4.86/D.435  n.d

Contents:
Lectures and publications
Background material, some annotated.

PENTENOATE  CSAC 113.4.86/D.436  1975

PENTENOATE  [no ref.]  1975

Contents:
Notes and drafts by Krebs, experimental results and data by D. Wiggins on effects of pentenoate on urea synthesis; work arising from a paper by A.M. Glasgow and H.P. Chase, a copy of which is included.
Various dates, March 1975 (some of Krebs's notes wrongly dated 1974).

L-GLUTAMATE TRANSPORT IN HEPATOCYTES  CSAC 113.4.86/D.437  1975

L-GLUTAMATE TRANSPORT IN HEPATOCYTES  [no ref.]  1975

Contents:
Draft and diagrams for paper, by A. Kleinzeller annotated by Krebs, n.d.; bibliographical note by Krebs, October 1975.

LACTATE  CSAC 113.4.86/D.438, D.439  1975-76

LACTATE  CSAC 113.4.86/D.438  1975-1976

Contents:
Notes and drafts on carbohydrate and lactate as fuels of respiration, September 1975.
Correspondence 1975, 1976 with A. Freminet including drafts of papers submitted for publication by Freminet.

LACTATE  CSAC 113.4.86/D.439  n.d

Contents:
Background material, some annotated.

METABOLISM OF BRANCHED-CHAIN AMINO ACIDS  CSAC 113.4.86/D.440-D.444  1975-76

Contents:
Drafts, notes, research material for lecture at Indianapolis and publication with P. Lund 'Aspects of the regulation of the metabolism of branched-chain amino acids' (Bibliog. 355). Most of the work is 1976 but see D.440 for earlier work by L.V. Eggleston.

METABOLISM OF BRANCHED-CHAIN AMINO ACIDS  CSAC 113.4.86/D.440  1970-1971

Contents:
Notes and results by Eggleston, 1970-71, with annotations and updating by Krebs.

METABOLISM OF BRANCHED-CHAIN AMINO ACIDS  CSAC 113.4.86/D.441  1976

Contents:
Extensive notes and drafts, discussions with P. Lund, D.H. Williamson for Indianapolis lecture, July-November 1976.

METABOLISM OF BRANCHED-CHAIN AMINO ACIDS  CSAC 113.4.86/D.442  n.d

Contents:
Miscellaneous undated notes, drafts, tables, etc. for lecture and paper.

METABOLISM OF BRANCHED-CHAIN AMINO ACIDS  CSAC 113.4.86/D.443  1975-1976

Contents:
Bibliographical references, 1975-76.

METABOLISM OF BRANCHED-CHAIN AMINO ACIDS  CSAC 113.4.86/D.444  n.d

Contents:
Background material, some annotated.

CHICK ENTEROCYTES  CSAC 113.4.86/D.445  1977

CHICK ENTEROCYTES  [no ref.]  1977

Contents:
Experimental results and research reports by J.W. Porteous (with some annotations by Krebs), June 1977. Porteous worked in Krebs's laboratory January-September 1977.

PURINE SYNTHESIS  CSAC 113.4.86/D.446-D.449  1977-81

PURINE SYNTHESIS  [no ref.]  1977-81

Contents:
Notes, drafts, research ideas, problems for collaborators, experimental results, etc., mainly by Krebs and D. Wiggins, but also by Hems and G. Livesy. Various dates, May 1977-October 1981 and undated; also some earlier material, 1969-70 (see D.446).
Related to Bibliog. 365, 393.

PURINE SYNTHESIS  CSAC 113.4.86/D.446  1969-1970

Contents:
'The Physiological Role of Liver Alcohol Dehydrogenase'
Material used as a basis of lectures of various centres between September 1969 and May 1970; with a ms. note 'Uppsala, Indianapolis, Philadelphia, New York Columbia, Reading, Chelsea, University College, Washington DC, Manchester'.
(Kept with later material.)

PURINE SYNTHESIS  CSAC 113.4.86/D.447  1977-78

Contents:
Papers

PURINE SYNTHESIS  CSAC 113.4.86/D.448  1979-81

Contents:
Papers

PURINE SYNTHESIS  CSAC 113.4.86/D.449  n.d

Contents:
Background material and references, some annotated.

GLUCAGON AND INSULIN IN BIRDS  CSAC 113.4.86/D.450  1978

Contents:
Brief correspondence and notes, January-February 1978.

GLUTAMINE METABOLISM  CSAC 113.4.86/D.451-D.453  1978-79

GLUTAMINE METABOLISM  CSAC 113.4.86/D.451  1978-1979

Contents:
Ms. and typescript notes and drafts, diagrams, etc., a few only dated November 1978-October 1979, some probably intended for a lecture. Work related to Bibliog. 378, 381.

GLUTAMINE METABOLISM  CSAC 113.4.86/D.452  n.d

Contents:
Bibliographical references.

GLUTAMINE METABOLISM  CSAC 113.4.86/D.453  n.d

Contents:
Background material, including some draft papers by others, some annotated by Krebs.

CALCIUM CONCENTRATION IN SALINE  CSAC 113.4.86/D.454  1979

CALCIUM CONCENTRATION IN SALINE  [no ref. or date]

Contents:
Notes, drafts, background material, April 1979.
Also included are correspondence with H. Rasmussen, 1969, and papers by Rasmussen and Nagata, 1969-70, to which Krebs refers in his notes.

BENZOATE  CSAC 113.4.86/D.455-D.458  1979-81

Contents:
The results of this collaborative work were not published until after Krebs's death, in Biochem, J., 1983 (Bibliog. 396). Many of his notes and drafts are of very late date.

BENZOATE  CSAC 113.4.86/D.455  1979-1981

Contents:
Correspondence with A. Sols suggesting collaborative research on the topic, discussing results and drafts, etc., 1979-81. Also includes Krebs's letter to A.J. Sinskey requesting a meeting at Harvard to discuss benzoate.

BENZOATE  CSAC 113.4.86/D.456  1979-1981

Contents:
Drafts and notes, 1979-81. Krebs's latest dated note is 18 September. Work continues in the hand of D. Wiggins to December.

BENZOATE  CSAC 113.4.86/D.457  n.d

Contents:
Drafts and comments for published paper (Bibliog. 396).

BENZOATE  CSAC 113.4.86/D.458  1981

Contents:
Ms. and typescript draft for a slide lecture on benzoic acid at Baltimore (ms. dated November 1979) and part of another talk or lecture, April 1981.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.459-D.511  1979-81

Contents:
The term 'evolution' is used ambiguously - as it was by Krebs - to cover the history or sequential tracing of metabolic pathways and more philosophical concepts of purpose and necessity; in this latter respect it forms a link with Krebs's ideas on 'Teleology' almost thirty years previously (D.101-D.111).
The immediate trigger for the work was an invitation in 1979 to give the Dunham Lectures at Harvard in April 1981. Krebs's original intention was to lecture on juvenile delinquency, but he was persuaded to choose a topic more closely related to his life's work in biochemistry. He turned his mind immediately to the ideas and material to be included (R. Hems, personal communication 1984) and envisaged the lectures as a summation of the thinking on metabolic processes which he had expressed in more piecemeal fashion in previous research projects and publications. His third lecture enabled him to include some discussion of social and moral evolution, or order in society, which had become of increasing concern to him.
During the lengthy gestation of the Dunham Lectures, Krebs took the opportunity to give several lectures, and to publish several papers on the subject. Among these was the collaborative article with J.E. Baldwin in Nature (Bibliog. 385); Baldwin had suggested to Krebs in March 1980 an important reason why direct oxidation of acetate could not provide on alternative to the citric acid cycle, and Krebs acknowledged his help in other papers, as well as referring to it constantly in his notes, drafts and lectures. The Dunham Lectures themselves were not published, as Krebs died before he could complete the manuscript (see especially D.502-D.505).
The surviving material is very extensive and indicates the importance Krebs placed on the topic and his wish to explore it adequately. Many of the drafts overlap, were cannibalised for later work or extended to incorporate new ideas resulting from discussions, correspondence or reading. The allocation of material is therefore hazardous. It is presented here as follows:
D.459-D.473 Notes and drafts
D.474-D.490 Lectures, papers, publications
D.491-D.505 The Dunham Lectures
D.506-D.510 Correspondence
D.511 Background material
For further material on Krebs's visit to Harvard for the Dunham Lectures, see F.346-F.349.
For additional research notes and ideas, see D.94-D.96, and the 'jotters' for the relevant period.
Notes and drafts
In approximate chronological order; sequences kept together by Krebs on a particular topic have been retained (see, e.g., D.460, D.464, D.468, D.469). The importance to Krebs of his discussion with J.E. Baldwin on 30 March 1980 is very apparent form the notes.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.459  June, October 1979

Contents:
Brief notes only.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.460  April 1980

Contents:
Contents of a plastic envelope inscribed 'History', mainly notes and drafts arising from Krebs's discussion with J.E. Baldwin on 30 March. The two main topics are 'Comments on the oxidizability of acetic acid in living material' and 'The Evolution of the citric acid cycle and other metabolic cycles'; drafts for the latter are in a 'jotter' similar to those in Section A and there is also a ms. draft letter to Baldwin on the importance of his idea.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.461  April 18-30 1980

Contents:
Includes 12pp. 'Comments on the evolution of metabolic cycles' as well as shorter notes.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.462  May 1980

Contents:
Notes on 'Cycles' of 13 May incorporate earlier notes on 'Cyclic Processes' dated August 1971.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.463  June-August 1980

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.464  1980

Contents:
Contents of a plastic envelope inscribed 'Reaction Mechanisms'; various notes, drafts, calculations and diagrams, bibliographical references, a few dated April, October 1980.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.465  September-December 1980

Contents:
Includes notes arising from further discussions with Baldwin, comments on joint paper in Nature, etc.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.466  January 1981

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.467  March-May 1981

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.468  some dated May, June 1981

Contents:
Contents of a plastic envelope inscribed 'Evolution general. Creationism. Popper'; notes, drafts, background material

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.469  June 1981

Contents:
Contents of a plastic envelope inscribed 'Multiple Use of Resources'; includes notes of discussion with G. Pontecorvo

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.470  June-August 1981

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.471  September, October 1981

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.472, D.473  Undated

2 folders.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.474  [n.d.]


Related information: See H.420.

Contents:
Lectures, papers, publications
'Cyclic Processes in Biology'
25pp. typescript draft, with a ms. note 'For Italian Encyclopaedia'; latest reference 1976. Not listed in Bibliography.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.475  1980-1981

Contents:
Lectures, papers, publications
'The Evolution of Metabolic Pathways'
Two typescript and ms. drafts, 19pp. with different annotations.
The talk was given as a slide lecture at Miami, November 1980; a set of slides, notice of lecture and letter of thanks from Freshman Student audience are included. One of the drafts is headed 'Edinburgh Reading', and the other 'Talk Edinburgh Meeting of Soc. Gen. Microbiol.' and has a ms. addendum. (The meeting was held in September 1981 and the paper was published in the Symposium Proceedings (Bibliog. 387).
Also included is a notice of two lectures given by Krebs in November 1980 at Medical College of Georgia, on 'The Evolution of Metabolic Cycles' and 'The History of the TCA Cycle'.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.476-D.483  1980-1981

Contents:
Lectures in German, on the evolution of the citric acid cycle and other metabolic cycles, given on various occasions November 1980-June 1981, at Halle, Göttingen, Düsseldorf, Lindau and possibly other locations. The texts are basically the same, but all have different ms. corrections, deletions, amendments, etc., and some have indications of where given. (SUPP. Bibliog. 62.)

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.476  n.d

Contents:
'Halle 11.11.80'
10pp. typescript and ms.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.477  n.d

Contents:
'Über die Evolution des Citronensäurecyklus und andere cyklischer Stoffwechselwege', with a note 'Halle script' and a 3pp. summary headed 'Lindau Halle Posted 1.5.81'

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.478  1980

Contents:
'Lecture Göttingen 27.5.80'
Ms. and typescript drafts, and a letter, June.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.479  n.d

Contents:
17pp. typescript and ms. draft headed 'Dusseldorf Lindau'.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.480  n.d

Contents:
Another version, more heavily corrected.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.481  1982

Contents:
12pp. typescript and ms. draft, heavily corrected, headed 'Lindau' and 'Use at München 1982'.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.482  1982
Language:  German

Contents:
Typescript drafts of lectures on evolution of citric acid cycle (9pp.) and on evolution of citric acid and other metabolic cycles (12pp.).

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.483  1981
Language:  German

Contents:
Miscellaneous shorter drafts for lectures, 1981.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.484-D.486  [n.d.]

Contents:
Drafts and material for Nature article (Bibliog. 385).

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.484  1980

Contents:
Ms. and typescript version of article as first drafted by Krebs under his name only; sent to Baldwin with covering letter, October 1980.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.485  n.d

Contents:
Three versions of above, all with variations and alterations following discussions with or comments from Baldwin. Miscellaneous loose pages of amendments and corrections.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.486  n.d

Contents:
Draft with Baldwin's and Krebs's names. Reprint of paper as published, with copy of earlier paper (Bibliog. 387) marked with deletions and alterations to be used as basis for Nature article.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.487  n.d

Contents:
'Evolutionary concepts in biological thought'.
Originally given as a 'keynote' lecture and subsequently published (Bibliog. 386). Two versions, with different texts and corrections.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.488  1980-1981

Contents:
'The Evolution of Metabolic Pathways'.
Heavily-corrected draft of talk given at meeting of Soc. Gen. Microbiol., Edinburgh, 1981, prepared for publication (Bibliog. 387), 23pp.
Includes 3pp. summary sent to symposium organiser, October 1980, and brief note from J.R. Krebs commenting on the draft.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.489  n.d

Contents:
Miscellaneous shorter drafts, notes, references.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.490  n.d

Contents:
Reprints of Krebs's publications kept with material (Bibliog. 113, 293, 310, 351, 387).

EVOLUTION OF METABOLIC PATHWAYS  [no ref.]  1981

Contents:
The Dunham lectures. (Given at Harvard, 19, 21, 26 May 1981.)
The general title was 'Evolution and regulation of the metabolic pathways' and the topics covered were 'Why Cycles?, The Usefulness of the Evolutionary Process, Comprehension of Metabolic Organization'. The titles of the three chapters prepared for publication before Krebs's death were:
1. The Evolution of the Citric Acid Cycle
2. The Evolution of Other Metabolic Cycles
3. Linear Reaction Sequences

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.491  n.d

Contents:
Synopsis of all three lectures.
Miscellaneous drafts for introductory remarks.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.492  n.d

Contents:
'Lecture 1'
Multiple drafts, all with annotations, revisions, emendations, etc.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.493  n.d

Contents:
Miscellaneous notes, drafts, tables, probably intended for first lecture. Includes 'Comment on biochemical evolution' in which Krebs discusses the use of the term, and his report on audience reactions to a previous lecture by him on the subject.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.494  n.d

Contents:
'Lecture 2'
Miscellaneous ms. and typescript notes and drafts.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.495  n.d

Contents:
'Lecture III'
Ms. and typescript notes and drafts.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.496-D.501  [n.d.]

Contents:
Notes and drafts intended for Dunham lectures.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.496  1980

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.497  1981

Contents:
Papers

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.498  n.d

Contents:
On iatrogenic medicine (referred to in third Dunham lecture).

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.499  n.d

Contents:
Unidentified.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.500  n.d

Contents:
Slides, diagrams, comments on slides.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.501  n.d

Contents:
'Evolution, Harvard. Refs.'

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.502-D.505  [n.d.]


Related information: See also D.507.

Contents:
Drafts for proposed publication of Dunham lectures.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.502  1981

Contents:
Typescript of introductory remarks, and first three chapters, submitted to Harvard University Press after Krebs's death, December 1981.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.503  n.d

Contents:
Draft figures and tables.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.504  n.d

Contents:
Miscellaneous drafts as edited for book.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.505  1981-1982

Contents:
Editorial correspondence with Harvard University Press and with The Sciences re proposed book, 1981-82.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.506-D.510  [n.d.]

Contents:
Correspondence
Including data, background material, notes of discussions in preparation for Dunham lectures.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.506  n.d; 1979-81

Contents:
Blake, C.
Gest, H.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.507  1980; nd

Contents:
King, P.
Newsholme, E.A.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.508  1981

Contents:
Paulus, H.
Includes Paulus's paper on evolution of the ornithine cycle intended for inclusion in Krebs's book of the Dunham Lectures.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.509  1980

Contents:
Quayle, J.R.
Extensive notes, arrangements to meet, printed matter, etc.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.510  1981

Contents:
Walsh, C.

EVOLUTION OF METABOLIC PATHWAYS  CSAC 113.4.86/D.511  n.d

1 box.

Contents:
Background material

CITRATE CYCLE  CSAC 113.4.86/D.512  1980

CITRATE CYCLE  [no ref.]  n.d

Contents:
Brief ms. notes only, mainly related to an article by P.J. Randle; a copy of the article (annotated by Krebs) with a covering letter from Randle, is included.

HEPATOCYTES  CSAC 113.4.86/D.513, D.514  1981

Contents:
Contents of folder inscribed 'Hepatocytes 1981'. The notes and drafts run June-October 1981 and represent some of Krebs's last work, on isolated liver cells and preparation techniques, based in part on an examination of methods described in papers by P.O. Seglen. A posthumous collaborative paper related to the work, 'The effect of cysteine oxidation on isolated liver cells', appeared in 1983 (Bibliog. 395).

HEPATOCYTES  CSAC 113.4.86/D.513  1981

Contents:
Notes and drafts, June-October 1981 (last dated note is 26 October).

HEPATOCYTES  CSAC 113.4.86/D.514  n.d

Contents:
Undated ms. notes, folder of experimental data headed 'Seglen Comparison', 3pp. draft on 'Manipulation of isolated liver cells'. Also included are copies of earlier papers by Krebs on the subject, kept with the material (Bibliog. 347, 376).

MISCELLANEOUS NOTES  CSAC 113.4.86/D.515-D.548  1950-81


Related information: See the introductory note to Section D.

Contents:
D.515-D.529 A chronological sequence of dated material, 1950-81.
D.530-D.546 An alphabetical sequence of material referring to specific research topics.
D.547, D.548 Undated and unidentified notes.

Dated material (chronological)  [no ref. or date]

MISCELLANEOUS NOTES  CSAC 113.4.86/D.515  1950, 1957

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.516  1961, 1962, 1965, 1966

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.517  1967-69

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.518  1970

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.519  1971

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.520  1972-73

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.521  1974

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.522  1974-75

Contents:
Miscellaneous tabulated data by Krebs, D. Wiggins, R.C. Farrell, M. Stubbs, R. Hems

MISCELLANEOUS NOTES  CSAC 113.4.86/D.523  1975

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.524  1976

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.525  1977

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.526  1978

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.527  1979

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.528  1980

Contents:
Papers

MISCELLANEOUS NOTES  CSAC 113.4.86/D.529  1981

Contents:
Papers

Research topics (alphabetical)  [no ref. or date]

MISCELLANEOUS NOTES  CSAC 113.4.86/D.530  1975 and undated

Contents:
Acidosis
Aldolase

MISCELLANEOUS NOTES  CSAC 113.4.86/D.531  [n.d.]

Contents:
ATP

MISCELLANEOUS NOTES  CSAC 113.4.86/D.532  [n.d.]

Contents:
Citrate Synthase

MISCELLANEOUS NOTES  CSAC 113.4.86/D.533  1974-77

Contents:
Histidine and methionine

MISCELLANEOUS NOTES  CSAC 113.4.86/D.534-D.539  1974-78

Contents:
Isolated liver cells
A substantial collection of material, related to or developing from previous work on lysine but not kept with it.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.534  1974-75

Contents:
Notes and drafts, by Krebs, D. Wiggins, M. Stubbs.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.535  1977-78

Contents:
Notes and drafts, mainly on staining methods with trypan blue.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.536  n.d

Contents:
Drafts for paper given at Guildford (some pages dated June, July 1978). Two heavily-corrected typescript and ms. versions, one with title 'Criteria of metabolic competence of isolated hepatocytes' (Bibliog. 376).

MISCELLANEOUS NOTES  CSAC 113.4.86/D.537  n.d

Contents:
'An explanation for the inhibition of glucose synthesis from lactate by ethanol in isolated hepatocytes'
Two drafts, one with extensive corrections in the hand of M. Spry, for a paper so titled.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.538  1976

Contents:
Correspondence with T.F. Slater.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.539  [n.d.]

Contents:
Background material, some annotated.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.540  1969-70 & undated

Contents:
Ketone

MISCELLANEOUS NOTES  CSAC 113.4.86/D.541  1976

Contents:
Krogh principle

MISCELLANEOUS NOTES  CSAC 113.4.86/D.542  1974 & undated

Contents:
Mitochondria

MISCELLANEOUS NOTES  CSAC 113.4.86/D.543  c1980

Contents:
Mono-oxygenase

MISCELLANEOUS NOTES  CSAC 113.4.86/D.544  1972, 1977 & undated

Contents:
Pentose phosphate

MISCELLANEOUS NOTES  CSAC 113.4.86/D.545  1973

Contents:
Shuttles and Carriers
4pp. ms. draft, dated 28 January 1973, and with a ms. note attached 'For autograph hunters'.

MISCELLANEOUS NOTES  CSAC 113.4.86/D.546  n.d c1978

Contents:
Toxicity of glutamate

Undated and unidentified notes  CSAC 113.4.86/D.547-D.548  [n.d.]

Undated and unidentified notes  [no ref.]  n.d

Contents:
2 Folders, with Krebs's original designation 'Memos'.

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.549-D.569  [n.d.]

Contents:
With the exception of the binder at D.549, these are loose octavo sheets of the standard format used for the Memoranda and, like them, are usually dated. A few have specific topic headings but most are an extensive unalphabetised series of references to work on all aspects of metabolism drawn from a wide range of journals. They are all additional to the bibliographies and background material kept elsewhere in Section D and especially with the 'Research Projects' at D.101-D.514, and testify to the importance attached by Krebs to maintaining a continuous overview of current research.
The material is presented in year order as for as this is ascertainable.

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.549  Mainly 1957-65

Contents:
Spring-back binder, labelled 'References' on spine.

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.550  1960, 1961

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.551  1962

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.552  1963

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.553  1964

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.554  1965

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.555  1966

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.556  1967

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.557  1968

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.558  1969

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.559  1970

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.560  1971

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.561  1972

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.562  1973

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.563  1974

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.564  1975

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.565  1976

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.566  1977

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.567  1973

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.568  1979, 1980

Contents:
Papers

BIBLIOGRAPHICAL REFERENCES  CSAC 113.4.86/D.569  Undated or miscellaneous

Contents:
Papers

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