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Papers and correspondence of Patricia Hannah Clarke, b. 1919


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Reference CLARKE/
Former reference GB 0103 P.H. Clarke papers
Covering dates 1963 to 2002
Held by London University, University College London (UCL) Manuscripts Room
Extent 9 boxes. ca 260 items
Archival history The papers were received from Professor Clarke in 2002. Placed in the Library, University College London 2003.
Creators Clarke, Patricia Hannah, b 1919, biochemist

Administrative history:
Patricia Hannah Green was born in Pontypridd, Wales, on 29 July 1919. She studied at Howells School, Llandaff before winning a scholarship to the University of Cambridge to study Biochemistry. She entered Girton College in 1937, graduating in 1940. She then left Cambridge for war work at the Armament Research Department of the Ministry of Supply, initially relocated from Woolwich to Swansea, where she worked on the chemistry of explosives. She returned to biochemistry in 1944, joining B.C.J.G. Knight's research group at the Wellcome Research Laboratories at Beckenham, Kent. In 1940 she had married Michael Clarke and, following the birth of her two children in 1947 and 1949, Clarke stopped work in order to bring them up. She returned to part-time employment in 1951, working with S.T. Cowan at the National Collection of Type Cultures of bacteria, based at the Central Public Health Laboratory at Colindale, London. In 1953 Clarke resumed full-time work as Assistant Lecturer in the Department of Biochemistry at University College London. She remained at UCL for the rest of her career, being appointed Lecturer 1956, Reader 1966 and Professor of Microbial Biochemistry in 1974 (Professor Emeritus 1984). She was also Honorary Professorial Fellow at University of Wales Institute of Science and Technology 1984-1987 and Royal Society Kan Tong-Po Professor at the Chinese University of Hong Kong 1986. Clarke had many other professional commitments. She served on the Council of the Society for General Microbiology 1960-1970, the Executive Committee of the Biochemical Society 1978-1981 and the Council of the Freshwater Biological Association 1980-1984. Clarke also was a member of the Science Research Council (1979-1984), the Governing Body of Wye College (1980-1986), the Council of the London School of Hygiene and Tropical Medicine (1982-1984) and the Council of the University of Bath (1987-1993). Other commitments included the British National Bibliography Research Fund 1990-2000 and, locally, the Council of Cheltenham Ladies College 1984-1990 and the Board of Governors of Deer Park School, Cirencester 1988-1999. Clarke's entry in International Women in Science (ed. C.M.C. Haines, Oxford, 2001), summarises her scientific work as follows: 'Clarke's main research, with her students and colleagues, was on the properties and the evolution of bacterial enzymes. By selecting mutants with the ability to grow on novel substrates they obtained strains producing altered enzymes, altered transport systems and altered regulatory systems. They were the first to show that a single site mutation could result in altered substrate specificity. They also showed that a range of novel enzymes could evolve from successive single site mutations. She also collaborated with biochemical engineers in research on methods for producing and purifying bacterial enzymes for industrial use and became involved in developments in biotechnology'. For her contributions to microbial biochemistry, Clarke was elected FRS in 1976 (Leeuwenhoek Lecture 1979), serving on Council and as Vice-President 1981-1982.

Contents:
Creation of material: 1963 to 2002 (bulk, 1980s and 1990s). Catalogued by the National Cataloguing Unit for the Archives of Contemporary Scientists as NCUACS catalogue no.120/6/03, 56 pp. UCL ref: GB 0103 P.H. Clarke papers Biographical papers include autobiographical material compiled and assembled in connection with the preparation of her Personal Record as a Fellow of the Royal Society, a full curriculum vitae and a transcript of her video-tape interview for the Biochemical Society. There is also documentation of a number of the later honours she was accorded. Clarke's interest in school education in general and science teaching in particular, is documented, with papers relating to Deer Park School Cirencester of which Clarke was a Governor 1988-1999. Her concern for education is also reflected in her correspondence with local and national politicians, although other topics are covered. There is significant documentation of both Clarke's interest in the historical contribution of women scientists, and her concern to ensure that more women became scientists with career prospects the same as those of their male colleagues. The material was assembled by Clarke in connection with a number of specific activities: her 1991 lecture 'Women in Science at University College 1878-1978'; a Royal Society meeting on 'Women in Science and Technology: opportunities for change?', 28 May 1993; her service on the Committee on Women in Science, Engineering and Technology established in 1993 by William Waldegrave MP, Minister for Public Service and Science, whose report The Rising Tide was published in 1994; and a meeting on Women in Science at the Royal Society, 27 March 2001. There is documentation for a few of Clarke's publications from the 1980s on, most substantially her Royal Society Biographical Memoirs of colleagues Roger Yate Stanier and Malcolm Douglas Lilly and her entry on Muriel Robertson for the New Dictionary of National Biography. There is also an incomplete set of offprints of her published work. Lectures material includes documentation of her 1979 Royal Society Leeuwenhoek Lecture 'Experiments in microbial evolution: new enzymes, new metabolic activities' and the 19th J.D. Bernal Lecture on 'New directions in biology: basic science and biotechnology', delivered at Birkbeck College London, 1988. Societies and organisations material is not extensive. There is material relating to eight United Kingdom and overseas organisations, including the British National Bibliographical Research Fund and the Royal Society, chiefly its Archives Working Group and Library Committee, and the Palm Oil Research Institute of Malaysia and the Research Grants Council of Hong Kong. The material spans 1975-2001. Visits and conferences material covers some of Clarke's travel and attendance at meetings over the period 1971-1998, although documentation of the earlier visits is in the form of later typescript accounts compiled by Clarke from her diary entries. Of particular significance is the documentation of her visits to the Far East through the 1970s, 1980s and 1990s, including Singapore, Malaysia 1990-1992, China and Hong Kong. Correspondence forms the largest component in the collection. The bulk of this material was arranged by Clarke by group of correspondents and then further subdivided by individual correspondent, and it has been retained in this original order. There is correspondence with her fellow researchers at University College London, with colleagues in the UK and with fellow scientists in the USA and Europe. Few correspondents are represented by extended exchanges of letters, the exceptions being R.E. Drew and B.W. Holloway.



BIOGRAPHICAL, A.1-A.33  CLARKE/A  1976-2001

Former reference: SECTION A

25 items

BIOGRAPHICAL AND AUTOBIOGRAPHICAL  CLARKE/A/1  1977-2001

Former reference: A.1-A.17

13 items

'CV Personal Record for Royal Society etc'  CLARKE/A/1/1  1999

Former reference: A.1, A.2

Contents:
Contents of Clarke's envelope so inscribed. Autobiographical account compiled by Clarke for the author of her Biographical Memoir.

'Personal Record'  CLARKE/A/1/1/a  [n.d.]

Former reference: A.1

Contents:
37pp typescript autobiographical account.

Curriculum vitae; list of Clarke's PhD students with notes on their careers  CLARKE/A/1/1/b  [n.d.]

Former reference: A.2

Autobiographical video recording for the Biochemical Society  CLARKE/A/1/2  1993-1995

Former reference: A.3-A.6

Administrative history:
As part of the Biochemical Society's programme of video-taped interviews with leading biochemists, Clarke was interviewed by J. Gareth Morris at University College London on 10 May 1994.

'Video recording for the Biochemical Society 1994 (1)'  CLARKE/A/1/2/a  1994

Former reference: A.3, A.4

Contents:
Draft typescript text with later manuscript additions. 2 folders.

'Correspondence re Biochemical Society video recording 1994 (2)'  CLARKE/A/1/2/b  1993-1995

Former reference: A.5

Contents:
Correspondence re arrangements for interview and arising therefrom.

Typescript outline of contents of video recording  CLARKE/A/1/2/c  1994

Former reference: A.6

Lists of 'Published papers 1947-1992' and 'Some key papers and reviews'  CLARKE/A/1/3  1992

Former reference: A.7

Two autobiographical notes  CLARKE/A/1/4  2001

Former reference: A.8

Contents:
These typescript notes, written in July and August 2001 refer respectively to Clarke's biochemistry students from 1960 (prompted by receiving a postcard from one of the former students), and to the circumstances behind her appointment to a Chair at University College London.

Typescript accounts of research  CLARKE/A/1/5  1980, 1981

Former reference: A.9

Contents:
1980 account prepared for 'Academic innovation' series on research at University College London during the 1970s; 1981 reports prepared for visit to UCL of Science Research Council Visiting Group.

Biographical entry prepared for C.M.C. Haines, 'International Women in Science: a Biographical Dictionary to 1950' (ABC-Clio: Oxford, 2001)  CLARKE/A/1/6  2000-2001

Former reference: A.10

Contents:
Correspondence; biographial information sent to Haines; draft of entry.

' 'Secret' life of scientist Pat'  CLARKE/A/1/7  2001

Former reference: A.11

Contents:
Photocopy of profile by Di Alexander, 'Wilts & Glos. Standard', 1 March 2001.

Letter re post of Principal, Queen Elizabeth College, University of London  CLARKE/A/1/8  1977

Former reference: A.12

Award of Leverhulme Trust Emeritus Fellowship  CLARKE/A/1/9  1984, 1987

Former reference: A.13

Administrative history:
Clarke was awarded a grant for research on gene structure and function in Pseudomonas aeruginosa.

Contents:
Correspondence; reports on grant.

Correspondence re nomination of Clarke for appointment as Dame Commander of the British Empire  CLARKE/A/1/10  1984, 1985

Former reference: A.14

Administrative history:
Clarke declined the honour. A later (1985) note records her reasons for so doing and the note is annotated in 1998 with an indication that Clarke had not altered her views.

Award of Honorary Degree, University of Kent at Canterbury, July 1984  CLARKE/A/1/11  1984

Former reference: A.15

Contents:
Brief correspondenee re arrangements.

Award of Honorary Degree, Council for National Academic Awards, May 1990  CLARKE/A/1/12  1989-1990

Former reference: A.16

Contents:
Correspondence re arrangements.

Election to Honorary Membership, Society for General Microbiology, 1996  CLARKE/A/1/13  1997

Former reference: A.17

Contents:
Biographical outline from 'SGM Quarterly', February 1997.

PERSONAL CORRESPONDENCE  CLARKE/A/2  1976-2000

Former reference: A.18, A.19

2 items

'Personal misc correspondence'  CLARKE/A/2/1  1976-2000

Former reference: A.18

Contents:
Letters of congratulation, personal news, etc. In chronological order.

Correspondence with Sir Frederick Warner and R.F. Bud, Science Museum, re preservation of historic acetone fermentation plant at former Royal Naval Cordite Factory, Holton Heath, Dorset  CLARKE/A/2/2  1994

Former reference: A.19

EDUCATION ISSUES  CLARKE/A/3  1978-1997

Former reference: A.20-A.31

8 items

Administrative history:
Clarke had a longstanding concern for the quality of school education. She supported the comprehensive system of education and had a particular interest in science teaching in schools. She served as a Governor (Vice-Chairman) of Deer Park School Cirencester 1988-1999 and was Chairman of its curriculum committee.

National school education policies  CLARKE/A/3/1  1978-1997

Former reference: A.20-A.25

2 items

Correspondence  CLARKE/A/3/1/a  1991-1997

Former reference: A.20

Contents:
Chiefly correspondence with Secretaries of State of the Department of Education and Science (successively the Department for Education and the Department for Education and Employment) re issues in comprehensive school education.

Newspaper cuttings and other background information on education policy  CLARKE/A/3/1/b  1978-1996

Former reference: A.21-A.24

Contents:
4 folders.

Correspondence re education spending in Gloucestershire  CLARKE/A/3/2  1992-1995

Former reference: A.25

1 item

Deer Park School, Cirencester  CLARKE/A/3/3  1992-c1999

Former reference: A.26-A.29

3 items

'Science in schools', 2pp typescript account by Clarke of her association with Deer Park School; miscellaneous material re her last meeting as a governor  CLARKE/A/3/3/a  c 1999

Former reference: A.26

Opening of new Science Block, 1991  CLARKE/A/3/3/b  1991

Former reference: A.27

Administrative history:
At Clarke's suggestion Richard Dawkins, Reader in Zoology, University of Oxford, was asked to perform the opening ceremony. He accepted and the building was opened on 21 April.

Contents:
Correspondence with R. Dawkins; Clarke's words of welcome; photocopies of newspaper coverage.

School science projects  CLARKE/A/3/3/c  1992-1997

Former reference: A.28,A.29

Administrative history:
Deer Park School, partly prompted by Clarke, initiated a number of science projects. One, in conjunction with the University of Bath, was a large scale study of ant behaviour (1994).

Contents:
2 folders.

Stratford-upon-Avon Grammar School for Girls  CLARKE/A/3/4  1993

Former reference: A.30

1 item

Contents:
Correspondence and papers re opening of school science laboratory by Clarke, 30 September 1993.

Miscellaneous correspondence on education issues  CLARKE/A/3/5  1993-1996

Former reference: A.31

1 item

POLITICS  CLARKE/A/4  1986-1999

Former reference: A.32, A.33

2 items

Administrative history:
Clarke was a long-standing member of the Labour Party.

Contents:
Correspondence with government ministries and Clarke's local MP re various issues. In chronological order.

1986-1992  CLARKE/A/4/1  [n.d.]

Former reference: A.32

Contents:
Includes Clarke's criticisms of use of British bases for US attack on Libya, 1986, and of proposal to close remaining UK coal mines, 1992.

1993-1999  CLARKE/A/4/2  [n.d.]

Former reference: A.33

Contents:
Includes Clarke's support for a ban on tobacco advertising 1993-1995, and criticisms of treatment of asylum seekers 1995.

WOMEN IN SCIENCE, B.1-B.48  CLARKE/B  1979-2002

Former reference: SECTION B

44 items

Contents:
This is the one of the larger sections in the collection and documents both Clarke's interest in the historical contribution of women scientists and her concern to ensure that more women became scientists and that their career prospects were the same as those of their male colleagues. The material was assembled by Clarke in connection with a number of specific activities: her 1991 lecture 'Women in Science at University College 1878-1978'; a Royal Society meeting on 'Women in Science and Technology: opportunities for change?', 28 May 1993; her service on the Committee on Women in Science, Engineering and Technology established in 1993 by William Waldegrave, Minister for Public Service and Science, whose report 'The Rising Tide' was published in 1994; and and a meeting on Women in Science at the Royal Society, 27 March 2001. The bulk of the material was found in Clarke's envelopes. These formed a sequence running from A1 to F. This arrangement has been retained and the inscriptions on the envelopes reproduced in the catalogue entries. At the end of this sequence is material found separately.

'Women in Science A1 [...] General Reports'  CLARKE/B/1  c 1990s

Former reference: B.1-B.3

3 items

Contents:
Printed and photocopied typescript reports, papers etc. 3 folders. At B.1 is Clarke's typescript list of reports in A1. The list does not include all the material found.

'Women in Science A2. Scientists'  CLARKE/B/2  c 1990s

Former reference: B.4-B.7

4 items

Contents:
Printed and photocopied typescript reports, papers etc on individual women scientists.

Individual women scientists, A.-H.  CLARKE/B/2/1  [n.d.]

Former reference: B.4

Contents:
Material on M. Anning, A. Arber, J.B. Burnell, C. Haslett, D.M.C. Hodgkin.

Individual women scientists, I.-S.  CLARKE/B/2/2  [n.d.]

Former reference: B.5

Contents:
Material on E.M. Inglis, K. Lonsdale, M. Rothschild, M. Somerville, M. Stephenson.

General contributions  CLARKE/B/2/3  [n.d.]

Former reference: B.6

Contents:
Material on contributions by women scientists to particular scientific disciplines.

Academic performance of women at university  CLARKE/B/2/4  1994

Former reference: B.7

Contents:
Letter from N.G. McCrum, enclosing copy of article, with Clarke's reply.

'Women in Science B1. UCL Historical'  CLARKE/B/3  1979-1991

Former reference: B.8-B.11

4 items

Contents:
Material on position of women academics, particularly scientists, at University College London. At B.8 is Clarke's typescript list of papers in B1 and B2. The list does not include all the material found.

Typescript drafts and printed copy of Clarke's lecture 'Women in Science at University College 1878-1978'  CLARKE/B/3/1  1991

Former reference: B.8

Correspondence re Clarke's lecture 'Women in Science at University College'  CLARKE/B/3/2  1991

Former reference: B.9

Draft report and related material on equal opportunities at University College London  CLARKE/B/3/3  1984

Former reference: B.10

Printed and photocopied material on women scientists at UCL  CLARKE/B/3/4  c 1979

Former reference: B.11

'Women in Science B2. UCL scientists'  CLARKE/B/4  c 1990s

Former reference: B.12-B.15

3 items

Lists of women UCL science graduates 1878-1905 and women Fellows of the Royal Society; manuscript notes and photocopied material on women scientists  CLARKE/B/4/1  [n.d.]

Former reference: B.12

Printed and photocopied material relating to Kathleen Lonsdale  CLARKE/B/4/2  [n.d.]

Former reference: B.13, B.14

Contents:
2 folders.

Photocopied material relating to Agnes Arber  CLARKE/B/4/3  [n.d.]

Former reference: B.15

'Women in Science C. Meeting at Royal Society 1993'  CLARKE/B/5  1993

Former reference: B.16-B.19

4 items

Administrative history:
Clarke chaired the panel discussion at the meeting and helped compile the final report. One of the features was a questionnaire handed out to those present; the results were analysed in the report.

Contents:
Papers re Royal Society meeting on 'Women in Science and Technology: opportunities for change?', 28 May 1993.

Programme; handout presented by J.B. Burnell  CLARKE/B/5/1  [n.d.]

Former reference: B.16

Spiral bound final report of the meeting  CLARKE/B/5/2  [n.d.]

Former reference: B.17

Typescript reports on the meeting by J. Mason, P. Nuttall and C. Turley  CLARKE/B/5/3  [n.d.]

Former reference: B.18

Questionnaires on women in science  CLARKE/B/5/4  [n.d.]

Former reference: B.19

Conditions of access: Restrict?

'Women in Science D1. The Rising Tide. Publications'  CLARKE/B/6  1992-1994

Former reference: B.20-B.24

5 items

Administrative history:
This material and that in D2 (B.25-B.28) relate to Clarke's service on the Committee on Women in Science, Engineering and Technology, set up by W. Waldegrave MP, Chancellor of the Duchy of Lancaster and Minister for Science, in 1993. It was established following on from the government White Paper 'Realising our potential: a strategy for Science, Engineering and Technology' Cmnd 2250 (1993). The Committee's report 'The Rising Tide' was published in 1994.

Copy of 'Realising our potential: a strategy for Science, Engineering and Technology' Cmnd 2250 (1992)  CLARKE/B/6/1  1992

Former reference: B.20

Correspondence and papers arising from White Paper  CLARKE/B/6/2  1992-1993

Former reference: B.21

Contents:
Includes letter from N.J. Lane to Clarke seeking her views on women in science, with Clarke's reply, September 1992.

Copy of 'The Rising Tide. A report on Women in Science, Engineering and Technology'  CLARKE/B/6/3  1994

Former reference: B.22

Spiral bound notebook labelled 'PH Clarke OST Women in Science 1993'  CLARKE/B/6/4  1993

Former reference: B.23

Contents:
Manuscript notes from launch of the report in February 1994.

Papers on the response to the report  CLARKE/B/6/5  1994

Former reference: B.24

Contents:
Includes 'Women in Science, Engineering and Technology', the official government response, and press-releases on government measures arising therefrom.

'Women in Science D2. The Rising Tide. OST Committee correspondence'  CLARKE/B/7  1993-1994

Former reference: B.25-B.28

4 items

Contents:
Chiefly papers of the Committee and its work; press cuttings on the reception of the report.

'Issues to be addressed'; minutes of meetings of the Committee  CLARKE/B/7/1  1993-1994

Former reference: B.25

Comments on and section of draft report  CLARKE/B/7/2  1993

Former reference: B.26

Newspaper and magazine coverage of the launch of the report  CLARKE/B/7/3  1994

Former reference: B.27

Contents:
Also includes newspaper cuttings re the broader issue of women in science.

Letter re activities of Cornwall Women in Engineering Science & Technology  CLARKE/B/7/4  1994

Former reference: B.28

Contents:
With enclosures and Clarke's reply.

'Women in Science E. Royal Society'  CLARKE/B/8  1992-1995

Former reference: B.29-B.32

4 items

Administrative history:
The material chiefly concerns the Royal Society's celebration of the fiftieth anniversary of admission of the first women to the Fellowship of the Royal Society in 1945.

Correspondence re 'The admission of the first women to the Royal Society of London' by J. Mason, Notes & Records of the Royal Society, vol 46 (1992)  CLARKE/B/8/1  1992

Former reference: B.29

Contents:
Includes offprint.

Programme for exhibition on 'Women in Botany: from Drawing Room to Laboratory'  CLARKE/B/8/2  1994

Former reference: B.30

Royal Society meeting on The Rising Tide - the next wave', Royal Society, London, 19 April 1995  CLARKE/B/8/3  1995

Former reference: B.31

Contents:
Letter to Clarke re the programme; list of participants; exhbition brochure.

'The women Fellows' jubilee' by J. Mason  CLARKE/B/8/4  1995

Former reference: B.32

Contents:
16pp typescript.

'Women in Science F. Women in Science Newsletter. AWISE [Association for Women in Science and Engineering]'  CLARKE/B/9/  1992-1998

Former reference: B.33-B.35

2 items

Women and Science newsletters  CLARKE/B/9/1  1992-1994

Former reference: B.33

Contents:
Issues 1-11.

Association for Women in Science and Engineering and related material  CLARKE/B/9/2  c 1993-1998

Former reference: B.34, B.35

Contents:
2 folders.

'Women'  CLARKE/B/10  1996-1998, n.d.

Former reference: B.36-B.38

3 items

Contents:
Contents of Clarke's folder so inscribed divided into three for ease of reference.

Reports from the Office of Science and Technology's Development Unit on Women in Science, Engineering and Technology  CLARKE/B/10/1  1996

Former reference: B.36

Printed material on women in science and academia  CLARKE/B/10/2  1998

Former reference: B.37

Miscellaneous typescript and manuscript material  CLARKE/B/10/3  n.d.

Former reference: B.38

Material on women in science found separately  CLARKE/B/11  1987-2002

Former reference: B.39-B.48

8 items

Miscellaneous correspondence  CLARKE/B/11/1  1987-1997

Former reference: B.39

Science Policy Support Group Policy Analysis Forum on Women in Science, London, 13 March 1992  CLARKE/B/11/2  1992

Former reference: B.40

Contents:
Programme; list of participants; information; Clarke's manuscript notes on proceedings

Correspondence re Dorothy Hodgkin Fellowships  CLARKE/B/11/3  1995, 1999

Former reference: B.41

Administrative history:
Clarke served on the Royal Society's Dorothy Hodgkin Fellowship selection panel B from 1995 to 1999 when she resigned.

Correspondence with J. Mason and H. Rose  CLARKE/B/11/4  1998

Former reference: B.42

Contents:
Correspondence re inaccuracies in Rose's Foreword to 'Women, Science and Medicine 1500-1700'.

Royal Society meeting on Women in Science, Royal Society, London, 27 March 2001  CLARKE/B/11/5  2001

Former reference: B.43-B.45

Invitation; programme; information; Clarke's manuscript notes on proceedings  CLARKE/B/11/5/1  [n.d.]

Former reference: B.43

Printed background information on schemes to promote women in science  CLARKE/B/11/5/2  [n.d.]

Former reference: B.44, B.45

Contents:
2 folders.

Information about opportunities for women scientists in the European Molecular Biology Organisation.  CLARKE/B/11/6  2002

Former reference: B.46

Newspaper and magazine cuttings  CLARKE/B/11/7  [n.d.]

Former reference: B.47

Contents:
The cuttings relate to women in science and opportunities for women in other careers.

Miscellaneous material  CLARKE/B/11/8  n.d.

Former reference: B.48

PUBLICATIONS AND LECTURES, C.1-C.54  CLARKE/C  1972-2000

Former reference: SECTION C

48 items

PUBLICATIONS  CLARKE/C/1  1972-2000

Former reference: C.1-C.43

38 items

'Introduction: Pseudomonas aeruginosa, an opportunist pathogen', in Pseudomonas Infection and Alginates: biochemistry, genetics and pathology, eds. P. Gacesa and N.J. Russell (London: Chapman & Hall, 1990).  CLARKE/C/1/1  1987-1989

Former reference: C.1, C.2

2 items

Administrative history:
This planned book arose from a workshop on Extracellular virulence factors of Pseudomonas aeruginosa, held at Gregynog Hall, University of Wales, 15-17 September 1986. See also E.18.

Draft of chapter  CLARKE/C/1/1/a  1988

Former reference: C.1

Contents:
16pp typescript.

Correspondence with editors and publishers  CLARKE/C/1/1/b  1987-1989

Former reference: C.2

'Microbes for the control of pollution'  CLARKE/C/1/2  1985

Former reference: C.3-C.5

1 item

Administrative history:
This was found in an envelope inscribed '[...] Commissioned 1985 by the ILB. Deposited not published. Invited by B.R. Rabin'.

Contents:
144pp typescript. 3 folders.

'Regulation of Expression of Microbial Genes', in Further milestones in biochemistry, eds M.G. Ord and L.A. Stocken, Greenwich, Conn. JAI Press, 1997, pp 234-273  CLARKE/C/1/3  1996-1997

Former reference: C.6-C.11

6 items

45pp typescript draft, May  CLARKE/C/1/3/a  1996

Former reference: C.6

References, tables, figures for preceding draft  CLARKE/C/1/3/b  [n.d.]

Former reference: C.7

46pp copy edited typescript  CLARKE/C/1/3/c  1997

Former reference: C.8

References, tables, figures for copy edited draft  CLARKE/C/1/3/d  1997

Former reference: C.9

Proof copy  CLARKE/C/1/3/e  1997

Former reference: C.10

Correspondence etc.  CLARKE/C/1/3/f  1996-1997

Former reference: C.11

'Muriel Robertson 1883-1973', New Dictionary of National Biography  CLARKE/C/1/4  1974-1999

Former reference: C.12-C.14

3 items

Typescript draft  CLARKE/C/1/4/a  1996

Former reference: C.12

Correspondence with editors and others  CLARKE/C/1/4/b  1994-1999

Former reference: C.13

Background information on Robertson  CLARKE/C/1/4/c  1974-1997

Former reference: C.14

'Roger Yate Stanier 1916-1982', Biographical Memoirs of Fellows of the Royal Society vol 32 (1986)  CLARKE/C/1/5  1983-1986

Former reference: C.15-C.19

5 items

Contents:
See also F.73.

Off-print of the Memoir  CLARKE/C/1/5/a  [n.d.]

Former reference: C.15

Correspondence with friends and colleagues of Stanier  CLARKE/C/1/5/b  1983

Former reference: C.16

Contents:
Letters to Clarke giving information about and reminiscences of Stanier.

Background information on Stanier  CLARKE/C/1/5/c  1983

Former reference: C.17

Contents:
Includes 4pp typescript on Stanier by W.C. Evans

Letters commenting on Clarke's draft  CLARKE/C/1/5/d  1985

Former reference: C.18

Letters of appreciation to Clarke  CLARKE/C/1/5/e  [n.d.]

Former reference: C.19

'Malcolm Douglas Lilly 1939-1998', Biographical Memoirs of Fellows of the Royal Society vol 46 (2000)  CLARKE/C/1/6  1998-2001

Former reference: C.20-C.31

10 items

Administrative history:
Lilly undertook postgraduate reseach under Clarke at University College London 1959-1962. He remained at UCL for the rest of his career, being appointed Professor of Biochemical Engineering in 1979.

26pp typescript draft  CLARKE/C/1/6/a  2000

Former reference: C.20

Draft bibliography  CLARKE/C/1/6/b  2000

Former reference: C.21

Contents:
30pp typescript.

Off-print  CLARKE/C/1/6/c  2000

Former reference: C.22

Correspondence and papers from the Royal Society  CLARKE/C/1/6/d  1998-2001

Former reference: C.23

Contents:
Includes invitation to write the memoir and copies of information on Lilly held by the Royal Society, and later correspondence re publication.

Background information  CLARKE/C/1/6/e  1998-2000

Former reference: C.24

Contents:
Includes copy of the Guardian obituary of Lilly (18 June 1998), Lilly's curriculum vitae; transcript of autobiographical tape-recording; etc.

Clarke's typescript and manuscript notes on Lilly's life, the structure of the memoir; sources to be consulted.  CLARKE/C/1/6/f  1998-1999

Former reference: C.25

Clarke's lists of friends and colleagues of Lilly  CLARKE/C/1/6/g  [n.d.]

Former reference: C.26

Correspondence from friends and colleagues of Lilly  CLARKE/C/1/6/h  1999-2000

Former reference: C.27-C.29

Contents:
Letters to Clarke giving information about and reminiscences of Lilly. Individual exchanges of correspondence are numbered by Clarke in a sequence from 3-44 (not complete).

3-29  CLARKE/C/1/6/h/1  [n.d.]

Former reference: C.27

31-37  CLARKE/C/1/6/h/2  [n.d.]

Former reference: C.28

41-44 and others  CLARKE/C/1/6/h/3  [n.d.]

Former reference: C.29

Contents:
Includes correspondence with Peter Dunnill, originally working as a co-author of the memoir.

Correspondence with Lilly's widow and letters of appreciation from friends and colleagues on completion of the memoir  CLARKE/C/1/6/i  1998-2001

Former reference: C.30

Spiral bound notebook  CLARKE/C/1/6/j  1998-2001

Former reference: C.31

Contents:
Labelled on front cover 'Malcolm Lilly RS Biog Memoir', used as a diary for work in progress on the memoir.

'An experiment in enzyme evolution: studies with Pseudomonas aeruginosa amidase', with R.E. Drew, Bioscience Reports vol 8 (1988)  CLARKE/C/1/7  1986-1988

Former reference: C.32

Contents:
Correspondence with editors.

Review of: M. Allaby, Facing the future: the case for science (London: Bloomsbury, 1995), in Science Progress  CLARKE/C/1/8  1995

Former reference: C.33-C.35

3 items

Contents:
This was originally entitled 'Beyond Doom: the case for science'. Much of the material is correspondence with publishers and M. Allaby re a reference queried by Clarke.

2pp typescript; 2pp earlier typescript draft annotated 'Replaced'  CLARKE/C/1/8/a  [n.d.]

Former reference: C.33

Correspondence with Science Progress  CLARKE/C/1/8/b  [n.d.]

Former reference: C.34

Correspondence with publishers and author  CLARKE/C/1/8/c  [n.d.]

Former reference: C.35

Review of: B. Gates, Kindred Nature: Victorian and Edwardian Women Embrace the Living World (Chicago, 1998), in Notes and Records of the Royal Society  CLARKE/C/1/9  1999

Former reference: C.36

Contents:
2pp typescript; proof copy.

Editorial correspondence  CLARKE/C/1/10  1984-1994

Former reference: C.37-C.42

5 items

Contents:
Arranged alphabetically by publishing house or journal.

Chapman and Hall  CLARKE/C/1/10/a  1988

Former reference: C.37

Contents:
Refereeing.

Nature  CLARKE/C/1/10/b  1990

Former reference: C.38

Contents:
Refereeing.

Pergamon Press  CLARKE/C/1/10/c  1988

Former reference: C.39

Contents:
Request for advice.

Science Progress  CLARKE/C/1/10/d  1984-1994

Former reference: C.40, C.41

Administrative history:
Clarke served as an editor of this journal, joint to 1989, then sole editor to 1994.

Contents:
Correspondence and papers re editorial policy, contributors, editorship. 2 folders.

Trends in Biotechnology  CLARKE/C/1/10/e  1990

Former reference: C.42

Contents:
Refereeing.

Offprints of articles by Clarke  CLARKE/C/1/11  1972-2000

Former reference: C.43

Contents:
Not a complete set.

LECTURES  CLARKE/C/2  1979-1998

Former reference: C.44-C.54

10 items

'Experiments in microbial evolution: new enzymes, new metabolic activities', Royal Society Leeuwenhoek Lecture, 8 November 1979  CLARKE/C/2/1  1978-1979

Former reference: C.44

Contents:
Correspondence re arrangements; notice; abstract.

'How to evolve a new microbe. A case study in enzyme evolution', 1982  CLARKE/C/2/2  1982

Former reference: C.45

Contents:
20pp typescript + tables and figures; manuscript list of slides. Manuscript note on front page 'Originally asked for manuscript for publication but did not follow up'.

'The scientific foundations of modern biotechnology', 2nd Encontro Nacional de Biotechnologia, Porto, Portugal, 1984  CLARKE/C/2/3  1984

Former reference: C.46

Contents:
30pp typescript + figures. Manuscript note on front page 'Asked for manuscript for publication but did not publish after all'.

'Tailoring bacterial enzymes', International Symposium on Microbiology in the Eighties, Singapore, May 1985  CLARKE/C/2/4  1985

Former reference: C.47

Contents:
15pp typescript + figures.

'Experiments on the evolution of bacteria with novel enzyme activities (Experimental evolution)', invited lecture at the Karolinska Institute, Stockholm, Sweden, 1985  CLARKE/C/2/5  1985

Former reference: C.48

Contents:
22pp typescript.

'Further Education Colleges and Polytechnics. The Scope and Implications', Department of Education and Science Invitation Conference on Biotechnology, Keble College, Oxford, 19-20 March 1986  CLARKE/C/2/6  1986

Former reference: C.49

Contents:
9pp typescript. See also E.17.

'The ubiquitous pseudomonads', European Molecular Biology Workshop, Geneva, Switzerland, September 1986  CLARKE/C/2/7  1986

Former reference: C.50

Contents:
17pp typescript + captions for figures.

'New directions in biology: basic science and biotechnology', 19th J.D. Bernal Lecture, Birkbeck College London, 12 May 1988  CLARKE/C/2/8  1987-1988

Former reference: C.51, C.52

29pp typescript draft + notes  CLARKE/C/2/8/a  1988

Former reference: C.51

Correspondence re arrangements; background material.  CLARKE/C/2/8/b  1987-1988

Former reference: C.52

'Protein engineering in vivo', Anniversary Congress of University of Groningen on Prospects in Protein Engineering, University of Groningen, The Netherlands, 14-18 August 1989  CLARKE/C/2/9  1989

Former reference: C.53

Contents:
Covering letter with 4pp typescript abstract; 7pp typescript with manuscript corrections; list of slides.

'The Human Genome Project', talk to Cirencester Science and Technology Society, 25 February 1998  CLARKE/C/2/10  1998

Former reference: C.54

Contents:
13pp typescript; copies of figures for overhead transparencies.

SOCIETIES AND ORGANISATIONS, D.1-D.25  CLARKE/D  1975-2001

Former reference: SECTION D

25 items

BRITISH NATIONAL BIBLIOGRAPHICAL RESEARCH FUND  CLARKE/D/1  1975-2001

Former reference: D.1-D.7

7 items

Administrative history:
This Fund was established in 1975 with funds from the British Library following the dissolution of the Council of the British National Bibliography Ltd (1949-1975). It supported bibliographic and related research in the UK. The Fund was taken over by by Resource, the Council for Museums, Archives and Libraries, in 2000 and abolished in 2001. Clarke represented the Royal Society on the Fund's Committee from 1991 and opposed its abolition.

Minutes of meetings  CLARKE/D/1/1  1990-2001

Former reference: D.1-D.3

3 items

Contents:
Also includes at D.1 letter of 18 October 1990 welcoming Clarke to the Committee.

Minutes  CLARKE/D/1/1/a  1990-1994

Former reference: D.1

Minutes  CLARKE/D/1/1/b  1995-1997

Former reference: D.2

Minutes  CLARKE/D/1/1/c  1998-2001

Former reference: D.3

Correspondence and papers re final years of the Committee  CLARKE/D/1/2  1998-2001

Former reference: D.4-D.7

4 items

Contents:
Includes lobbying to try to ensure the survival of the Committee.

1998-1999  CLARKE/D/1/2/a  [n.d.]

Former reference: D.4

2000  CLARKE/D/1/2/b  [n.d.]

Former reference: D.5

2001  CLARKE/D/1/2/c  [n.d.]

Former reference: D.6

Contents:
Includes report, for the record, on the work of the Fund written by Clarke for the Royal Society and brief note on her involvement with the Fund.

Background information  CLARKE/D/1/2/d  1992, 1998

Former reference: D.7

PALM OIL RESEARCH INSTITUTE OF MALAYSIA  CLARKE/D/2  1989-1992

Former reference: D.8

1 item

Administrative history:
Clarke served on the Biology Subcommittee of the Institute's Programme Advisory Committee 1990-1992. In connection with her membership she made a number of visits to Malaysia, some of which are documented further in section E.

Contents:
Correspondence and papers re meetings of the Subcommittee.

RESEARCH GRANTS COUNCIL OF HONG KONG  CLARKE/D/3  1988-2000

Former reference: D.9-D.14

6 items

Administrative history:
Clarke evaluated research projects for the Research Grants Council of Hong Kong.

Contents:
Correspondence and papers re assessment of projects.

Grant proposals  CLARKE/D/3/1  1988, 1991

Former reference: D.9

Work on indigo and sulfur black dye  CLARKE/D/3/2  1993

Former reference: D.10

Work on Bacillus subtilis  CLARKE/D/3/3  1993

Former reference: D.11

Work on Bacillus subtilis cloning  CLARKE/D/3/4  1998

Former reference: D.12

Work on cultured mycelial products of mushroom species  CLARKE/D/3/5  1999

Former reference: D.13

Work on cultured mushroom mycelia  CLARKE/D/3/6  2000

Former reference: D.14

ROYAL SOCIETY  CLARKE/D/4  1985-1997

Former reference: D.15-D.20

6 items

Administrative history:
Clarke was elected to the Fellowship of the Royal Society in 1976. She was on Council and a Vice-President 1981-1982 and served on a number of committees including the Research Grants Scheme Board 1997-1999, the Notes & Records Editorial Advisory Board 1989-1997, the Library Committee 1980-1990 (Chairman 1983-1990) and its Working Group on Archives Policy (Chairman 1985-1990), and the Advisory Committee to the National Cataloguing Unit for the Archives of Contemporary Scientists 1987-1997.

Contents:
The material, which is not extensive, chiefly documents Clarke's association with the Royal Society's Library Committee and its Working Group on Archives Policy.

Archives Working Group  CLARKE/D/4/1  1985-1989

Former reference: D.15, D.16

2 items

Invitation to serve, 1985; report, 1988  CLARKE/D/4/1/a  1985, 1988

Former reference: D.15

Reports  CLARKE/D/4/1/b  1988, 1989

Former reference: D.16

Library Committee  CLARKE/D/4/2  1990

Former reference: D.17-D.19

3 items

Minutes of Clarke's last meeting as chairman  CLARKE/D/4/2/a  1990

Former reference: D.17

'The Library of the Royal Society'  CLARKE/D/4/2/b  1990

Former reference: D.18

Contents:
12pp typescript annotated '1990 for Library Committee'.

Correspondence and papers re history of the Royal Society Library  CLARKE/D/4/2/c  1992

Former reference: D.19

Contents:
Clarke wrote the Foreword to 'The Library and Archives of the Royal Society' by M.B. Hall (London: Royal Society, 1992).

Miscellaneous correspondence  CLARKE/D/4/3  1987-1997

Former reference: D.20

SOCIETY FOR THE PROTECTION OF LEARNING AND SCIENCE  CLARKE/D/5  1986-1999

Former reference: D.21, D.22

2 items

Administrative history:
Clarke was invited to become a member of the Council of Management of the Society in 1986. She served to 1999.

Photocopy of invitation to serve, 1986; miscellaneous correspondence 1992-1999  CLARKE/D/5/1  1986-1999

Former reference: D.21

Minutes of meetings  CLARKE/D/5/2  1993-1999

Former reference: D.22

UNIVERSITY OF BATH  CLARKE/D/6  1993-1996

Former reference: D.23

1 item

Administrative history:
Clarke served on the Council of the University of Bath as a lay member to 1993.

Contents:
Correspondence re Council service.

UNIVERSITY OF KARACHI  CLARKE/D/7  1991-1993

Former reference: D.24

1 item

Contents:
Acting as external examiner

WYE COLLEGE, UNIVERSITY OF LONDON  CLARKE/D/8  1986

Former reference: D.25

1 item

Contents:
Letters re Clarke's resignation as a University of London representative on the Governing Body of Wye College.

VISITS AND CONFERENCES, E.1-E.36  CLARKE/E  1971-1998

Former reference: SECTION E

34 items

Contents:
The material includes later accounts prepared by Clarke in or around 1998.

Visit to Australia 1971  CLARKE/E/1  c 1998

Former reference: E.1

1 item

Administrative history:
Clarke spent her sabbatical in 1971 working with Bruce Holloway in his laboratory in the Department of Genetics, Monash University, Australia. She travelled via the USA, where she visited colleagues, and also gave some lectures in New Zealand.

Contents:
Clarke's typescript accounts of her travels in the USA, New Zealand and Australia. The accounts are based in part on her diary records.

Clarke's later typescript accounts of visits to Singapore and Malaysia during the 1970s, 1980s and 1990s  CLARKE/E/2  c 1998

Former reference: E.2

1 item

Discussion Meeting on New Horizons in Industrial Microbiology, Royal Society, London, 20-21 June 1979  CLARKE/E/3  1979

Former reference: E.3

1 item

Administrative history:
Clarke spoke on 'Microbiology and pollution: the biodegradation of natural and synthetic organic compounds'.

Contents:
Programme; correspondence arising.

Joint Royal Society/Science and Engineering Research Council visit to Japan, 14-24 April 1982  CLARKE/E/4  1984, 1988

Former reference: E.4-E.6

2 items

Administrative history:
Clarke was one of two Royal Society representatives (with Sir James Baddiley).

Report to the Royal Society  CLARKE/E/4/1  1982

Former reference: E.4

Clarke's typescript report on visit  CLARKE/E/4/2  1982

Former reference: E.5, E.6

Contents:
The report gives firstly her personal account of the visit and secondly, her reports on visits to individual science and technology institutions in Japan. 2 folders.

Meeting on Pseudomonas Genetics and their Biosurface Phenomenon, Warren Spring Laboratory, Stevenage, Hertfordshire, 14 October 1985  CLARKE/E/5  1985

Former reference: E.7

1 item

Contents:
Letter re arrangements, agenda; list of participants.

4th General Assembly of the International Foundation for Science, Rabat, Morocco, 15-18 October 1984  CLARKE/E/6  1984-c 1998

Former reference: E.8-E.10

2 items

Administrative history:
Clarke attended as the official UK delegate on behalf of the Royal Society.

Papers for the General Assembly  CLARKE/E/6/1  1984

Former reference: E.8, E.9

Contents:
2 folders.

1988 booklet on the IFS; note by Clarke on her participation at the General Assembly, c 1998.  CLARKE/E/6/2  1988, c 1998

Former reference: E.10

Visit to Hong Kong and China, January-February 1986  CLARKE/E/7  1984-1990

Former reference: E.11-E.16

6 items

Administrative history:
Clarke was invited to visit the Chinese University of Hong Kong (CUHK) on the Kan Tong Po Visiting Professorship Scheme. She gave a series of seminars to the Departments of Biology and Biochemistry on work on Pseudomonas aeruginosa and on 'Evolution of novel catabolic activities in bacteria'. She produced a report for the university on research in biotechnology. Clarke also visited the University of Hong Kong. The Royal Society then suggested Clarke extend her visit into later February and go on to China under the Exchange Scheme with the Academia Sinica.

Correspondence re arrangements to visit Hong Kong  CLARKE/E/7/1  1984-1985

Former reference: E.11

Notices for seminars by Clarke; biographical outline of Clarke.  CLARKE/E/7/2  [n.d.]

Former reference: E.12

Clarke's 'Report on Research and Teaching in Biotechnology at the Chinese University of Hong Kong, February; information on the Department of Biology at the CUHK.  CLARKE/E/7/3  1986

Former reference: E.13

Clarke's 'Report on visit to China under Exchange Scheme with Academia Sinica'; brochure on Shanghai Institute of Biochemistry.  CLARKE/E/7/4  1986

Former reference: E.14

Correspondence arising from visits to Hong Kong  CLARKE/E/7/5  1986, 1990

Former reference: E.15

Clarke's later typescript accounts of visits to Hong Kong and China  CLARKE/E/7/6  c 1998

Former reference: E.16

Department of Education and Science Invitation Conference on Biotechnology, Keble College, Oxford, 19-20 March 1986  CLARKE/E/8  1986

Former reference: E.17

1 item

Administrative history:
Clarke spoke on 'Further Education Colleges and Polytechnics. The Scope and implications', see C.49.

Contents:
Programme; list of participants.

Workshop on Extracellular virulence factors of Pseudomonas aeruginosa, Gregynog Hall, University of Wales, 15-17 September 1986  CLARKE/E/9  1985-1986

Former reference: E.18

1 item

Administrative history:
Clarke chaired the second session on Structural aspects of pathogenity - the organism. She contributed to the planned volume arising from the meeting, see C.

Contents:
Brief correspondence re arrangements; programme; manuscript notes.

Sixth Symposium of the Federation of Asian and Oceanic Biochemists, Karachi, Pakistan, October-November 1987  CLARKE/E/12  1987-c 1998

Former reference: E.19, E.20

2 items

Administrative history:
Clarke spoke on 'New products from microbial fermentations'. The proceedings were published in 1989.

7pp typescript draft of Clarke's contribution  CLARKE/E/12/1  1987

Former reference: E.19

Correspondence arising; Clarke's later account of the visit to Pakistan  CLARKE/E/12/2  1987, 1989, c 1998

Former reference: E.20

Contents:
Clarke's account was transcribed from notes taken at the time of the visit.

Visit to Malaysia, 22 March-7 April 1988  CLARKE/E/13  1988

Former reference: E.21, E.22

2 items

Administrative history:
Clarke visited the University of Malaya as External Examiner in Microbiology for the Department of Genetics and Cellular Biology. She also visited the Palm Oil Research Institute (see D.8) where she spoke on 'Recent developments in Biotechnology in Britain'.

Reports on the Department of Genetics and Cellular Biology  CLARKE/E/13/1  1988

Former reference: E.21

Itinerary; 7pp typescript notes for Clarke's talk on biotechnology; correspondence arising from visit  CLARKE/E/13/2  1988

Former reference: E.22

UK-Japan Biotechnology Workshop, Royal Society, London, 25-26 April 1988  CLARKE/E/14  1988

Former reference: E.23

1 item

Contents:
Programme; bound abstracts, annotated by Clarke.

Visit to Hong Kong, August 1988  CLARKE/E/15  1987-1988

Former reference: E.24-E.26

3 items

Administrative history:
Clarke visited Hong Kong to attend the 8th International Conference on Global Impacts of Applied Microbiology, held with the International Conference on Applied Biology and Biotechnology, Chinese University of Hong Kong, 1-5 August. She spoke on 'New enzymes from bacteria'. Clarke made other visits in Hong Kong on behalf of the British Council and the Royal Society

Correspondence re arrangements  CLARKE/E/15/1  1987-1988

Former reference: E.24

7pp annotated typescript of Clarke's contribution; 1p references.  CLARKE/E/15/2  [n.d.]

Former reference: E.25

Manuscript notes on visit; typescript reports to the British Council and Royal Society  CLARKE/E/15/3  1988

Former reference: E.26

Programme Advisory Commitee Seminar on Current Developments in Protein Engineering, Palm Oil Research Institute of Malaysia, 16 March 1990  CLARKE/E/16  1990

Former reference: E.27

1 item

Contents:
Programme; abstract; 9pp typescript.

Workshop on Library Provision for the Culture of Science, Technology and Medicine, Royal Society, London, 23 October 1990  CLARKE/E/17  1990

Former reference: E.28

1 item

Contents:
List of participants; typescript proceedings.

Royal Society Anniversary Day, 30 November 1990  CLARKE/E/18  1990

Former reference: E.29

1 item

Administrative history:
Clarke seconded the Vote of Thanks to the President of the Royal Society.

Contents:
Letter of invitation; programme; copy of proposal of vote of thanks and Clarke's 4pp typescript speech seconding it.

Meeting on J.B.S. Haldane: Science and Society, Science Museum London, 10-11 April 1992  CLARKE/E/19  1992

Former reference: E.30

1 item

Administrative history:
Clarke was a member of the organising committee. See also E.33-E.35 below.

Contents:
Programme; list of particpants; abstracts.

Programme Advisory Commitee meeting, Palm Oil Research Institute of Malaysia, 13-18 April 1992  CLARKE/E/20  1992

Former reference: E.31, E.32

2 items

Schedule and programme  CLARKE/E/20/1  [n.d.]

Former reference: E.31

Report on Status of palm oil tissue culture research in relation to abnormalities  CLARKE/E/20/2  [n.d.]

Former reference: E.32

Contents:
This was prepared for the meeting.

J.B.S. Haldane Centenary Meeting, University College London, 6 November 1992  CLARKE/E/21  1992

Former reference: E.33-E.35

3 items

Administrative history:
Clarke spoke on 'Haldane and Biochemistry: enzymes and the origin of life'. See also E.30 above.

7pp typescript of Clarke's lecture; figures for transparencies  CLARKE/E/21/1  [n.d.]

Former reference: E.33

Contents:
Also includes covering letter sent with abstract.

Abstracts of contributions  CLARKE/E/21/2  [n.d.]

Former reference: E.34

Background information on Haldane  CLARKE/E/21/3  [n.d.]

Former reference: E.35

Contents:
Includes Clarke's manuscript notes, photocopies and printed material.

Invitations declined  CLARKE/E/22  1985-1994

Former reference: E.36

CORRESPONDENCE, F.1-F.78  CLARKE/F  1963-2001

Former reference: SECTION F

75 items

Contents:
The bulk of this material was arranged by Clarke in envelopes organised by group of correspondents. It has been retained in this original order. Many of the envelopes are further subdivided by correspondent, sometimes with a later note by Clarke explaining her relationship with the correspondent. At F.74-F.78 is a little correspondence found loose.

'Bruce Holloway'  CLARKE/F/1  1963-2001

Former reference: F.1-F.7

7 items

Administrative history:
Bruce Holloway was an Australian colleague of Clarke's who made his career at Monash University, Victoria. Their association through research on Pseudomonas aeruginosa spanned some four decades and is described in Clarke's note of 2001 at F.

Contents:
Correspondence chiefly reporting on work on Pseudomonas aeruginosa and related research but also including arrangements for visits and with family, personal and social news of colleagues

Note by Clarke on B.W. Holloway, 2001; curriculum vitae 1970  CLARKE/F/1/1  1970, 2001

Former reference: F.1

1963-1967  CLARKE/F/1/2  [n.d.]

Former reference: F.2

Contents:
Correspondence re Pseudomonas genetics

1969-1975  CLARKE/F/1/3  [n.d.]

Former reference: F.3

Contents:
Work on P. aeruginosa strains; contribution to Genetics and Biochemistry of Pseudomonas, eds. Clarke and M.H. Richmond (London: Wiley, 1975); visits to UK.

1976-1981  CLARKE/F/1/4  [n.d.]

Former reference: F.4

Contents:
Chiefly genetic linkage mapping of Pseuodmonas.

1982-1985  CLARKE/F/1/5  [n.d.]

Former reference: F.5

Contents:
Visits and social news; P.aeruginosa gene mapping

1982, 1985  CLARKE/F/1/6  [n.d.]

Former reference: F.6

Conditions of access: Application for FRS 1982; Fulbright 1985

Contents:
Career

1988-1998  CLARKE/F/1/7  [n.d.]

Former reference: F.7

Contents:
Chiefly personal and social news.

'Pseudomonas Group Rob Drew'  CLARKE/F/2  1989-1998

Former reference: F.8-F.11

4 items

Administrative history:
Robert E. Drew was a colleague of Clarke's based at the University College London Department of Biochemistry and Molecular Biology

Contents:
Chiefly correspondence re work in progress, including drafts of work sent to Clarke for comment. Chiefly research on genetics of Pseudomonas aeruginosa, though later correspondence includes social and personal news.

1989-1990  CLARKE/F/2/1  [n.d.]

Former reference: F.8

Contents:
Includes typescript draft of 'Cloning, DNA sequence and purification of amicC, a new gene regulating expression of the Pseudomonas aliphtic amidase' by Drew and S.Wilson, sent to Clarke for comment.

1991-1992  CLARKE/F/2/2  [n.d.]

Former reference: F.9

Contents:
Includes typescript draft of 'Regulation of amidase expresion in Pseudomonas aeruginosa' by Drew and S. Wilson, sent to Clarke for comment, c 1992

1993, 1995  CLARKE/F/2/3  [n.d.]

Former reference: F.10

Contents:
Includes copy of presentation on 'The P. aeruginosa transcriptioin antiterminator AmiR, binds to the Leader mRNA in the amidase operan' by Drew et al.

1996-c2000  CLARKE/F/2/4  [n.d.]

Former reference: F.11

Contents:
Includes copy of presentation on 'Antitermination of amidase expression in Pseudomonas aeruginosa is controlled by a novel cytoplasmic amide-binding protein' by Drew et al.

'UCL Research Group Students etc'  CLARKE/F/3  1975-1996

Former reference: F.12-F.26

13 items

Contents:
Correspondence with former University College research students, laboratory workers and visiting researchers. Some have a note by Clarke giving some biographical information. Arranged in alphabetical order by surname.

Betz, J.L.  CLARKE/F/3/1  1985-1994

Former reference: F.12

Administrative history:
Betz was a Ph.D. student of Clarke's.

Daly, G.  CLARKE/F/3/2  1975

Former reference: F.13

Administrative history:
Greta Daly was a technician who studied for her B.Sc in biochemistry before moving to Australia.

Day, M.J.  CLARKE/F/3/3  1974-1995

Former reference: F.14

Administrative history:
Day was a research student of Clarke's who spent much of his career at the University of Wales, Cardiff.

Contents:
Includes correspondence re career.

Draper, P.  CLARKE/F/3/4  1984

Former reference: F.15

Contents:
With typescript note by Clarke.

Finer, N.  CLARKE/F/3/5  1984

Former reference: F.16

Administrative history:
Finer was an ex-technician of Clarke's.

Contents:
One letter only.

Karunakaran, V.  CLARKE/F/3/6  1990

Former reference: F.17

Conditions of access: Request for reference

Contents:
One letter only, re career.

Keshavaraz, T.  CLARKE/F/3/7  1985-2001

Former reference: F.18

Conditions of access: Includes job recommendations

Administrative history:
Clarke and M.D. Lilly supervised Keshavaraz's Ph.D. in biochemical engineering at University College London.

Contents:
Chiefly re career. With typescript note by Clarke.

Laverack, P.D.  CLARKE/F/3/8  1989, 1990

Former reference: F.19

Administrative history:
Laverack was a former technician in Clarke's laboratory.

Meadow, P.M.  CLARKE/F/3/9  1987, 1991

Former reference: F.20

Administrative history:
Pauline Meadow (married name Enticknap) held a Beit Fellowship for research with Clarke at UCL 1956-1957. They developed a research group and when her Fellowship ended she was appointed Lecturer. She later became Reader in Biochemistry and Sub-dean of the Medical Faculty.

Contents:
Brief correspondence.

Rice, P.M. and C.  CLARKE/F/3/10  1976-1994

Former reference: F.21, F.22

Administrative history:
Peter and Catherine Rice were Ph.D. students of Clarke's

1976-1979  CLARKE/F/3/10/a  [n.d.]

Former reference: F.21

Contents:
Typescript

1980-1994  CLARKE/F/3/10/b  [n.d.]

Former reference: F.22

Conditions of access: Includes job recommendations

Contents:
Chiefly re career.

Sambanthamurthi, R.  CLARKE/F/3/11  1982-1996

Former reference: F.23, F.24

Administrative history:
Sambanthamurthi was a Malaysian research student of Clarke's 1979-1983.

1982-1986  CLARKE/F/3/11/a  [n.d.]

Former reference: F.23

Contents:
Correspondence re studies and career. Also includes personal news.

1988-1996  CLARKE/F/3/11/b  [n.d.]

Former reference: F.24

Contents:
Chiefly personal and career news.

Sangodcar, U.  CLARKE/F/3/12  1986, 2002

Former reference: F.25

Contents:
One letter only, 1986, with later typescript note by Clarke.

Trewavas, A.  CLARKE/F/3/13  1999

Former reference: F.26

Contents:
One letter only.

'UCL Misc'  CLARKE/F/4  1982-1998

Former reference: F.27-F.32

6 items

Contents:
Correspondence with University College London colleagues. Arranged in alphabetical order by surname.

Armitage, J.P.  CLARKE/F/4/1  1995-1998

Former reference: F.27

Administrative history:
Armitage was a student on the UCL B.Sc. Microbiology course. After graduation in 1972 she went on to Ph.D. research. She remained at UCL to 1985 when she moved to Oxford. She was appointed Professor of Biochemistry at the University of Oxford in 1996.

Contents:
Correspondence and papers chiefly re career.

Banks, B.  CLARKE/F/4/2  1990

Former reference: F.28

Conditions of access: Request for reference

Administrative history:
Barbara Banks joined the UCL Biochemistry M.Sc. course in 1957. She did a Ph.D. in the Chemistry Department and then joined the Physiology Department.

Contents:
Career.

Bawden, L.-A.  CLARKE/F/4/3  1999

Former reference: F.29

Contents:
One letter only, with reminiscences.

Lighthill, M.J.  CLARKE/F/4/4  1998

Former reference: F.30

Administrative history:
The mathematician, Sir James Lighthill, was Provost of University College London. He gave strong support to science and technology and to the position of women in the College.

Contents:
Obituaries of Lighthill, including appreciation by Clarke, Guardian, 25 July 1998; letter of condolence to Lady Lighthill.

Man, D.  CLARKE/F/4/5  1981-1985

Former reference: F.31

Robson, E.B.  CLARKE/F/4/6  1984

Former reference: F.32

Administrative history:
Bette Robson was Head of the UCL Department of Genetics and Biometry.

Contents:
One letter only.

'Correspondence with scientists etc UK'  CLARKE/F/5  1968-1999

Former reference: F.33-F.56

25 items

Contents:
Correspondence with British scientists and other colleagues. Arranged in alphabetical order.

Ambler, R.P.  CLARKE/F/5/1  1972-2000

Former reference: F.33

Administrative history:
Ambler worked in the Edinburgh University Department of Molecular Biology.

Contents:
Correspondence re Clarke and Ambler's 'collaboration on the amino acid sequence of the amidase of Pseudomonas aeruginosa' Also includes exchange re commemoration meeting for M.R. Pollock, 2000.

Auffret, A.D.  CLARKE/F/5/2  1988

Former reference: F.34

Administrative history:
Auffret worked with R.P. Ambler at Edinburgh on the amidase sequence.

Contents:
Exchange re work on amidase.

Billing, E.  CLARKE/F/5/3  1978

Former reference: F.35

Contents:
Strains of Erwinia.

Brenner, S.  CLARKE/F/5/4  1968

Former reference: F.36

Contents:
Strains of Pseuodmonas aeruginosa.

Buchanan, B.J.  CLARKE/F/5/5  1997, 1998

Former reference: F.37

Contents:
Correspondence re Waltham Abbey connection.

Buchanan, R.A.  CLARKE/F/5/6  1995-1998

Former reference: F.38

Contents:
Correspondence re history of science and personal news.

Cambridge Biochemistry Department  CLARKE/F/5/7  1976-1999

Former reference: F.39-F.44

6 items

Contents:
Correspondence with colleagues associated with the Department of Biochemistry at Cambridge. A typescript note by Clarke (F.39) lists the correspondents and explains her relationship with them.

Bacon, J.S.D.  CLARKE/F/5/7/a  1982

Former reference: F.39

Corran, H.S.  CLARKE/F/5/7/b  1992-1999

Former reference: F.40

Contents:
Chiefly personal news and news of colleagues. Includes 3pp typescript of Corran's obituary of their mutual friend R.L.M. Synge, 1994.

Elsden, S.R.  CLARKE/F/5/7/c  1976-1981

Former reference: F.41

Contents:
Includes correspondence re Stickland-type reaction.

Gale, E.F.  CLARKE/F/5/7/d  1991-1995

Former reference: F.42

Contents:
Chiefly personal news.

Harris, H.  CLARKE/F/5/7/e  1995

Former reference: F.43

Heyningen, R. van  CLARKE/F/5/7/f  1996-1997

Former reference: F.44

Contents:
Personal correspondence.

Davies, M.  CLARKE/F/5/8  1982

Former reference: F.45

Dawes, E.A.  CLARKE/F/5/9  1976

Former reference: F.46

Contents:
Exchange re 100th volume of the Journal of General Microbiology.

Derewenda, Z.  CLARKE/F/5/10  1989

Former reference: F.47

Howe, T.G.B.  CLARKE/F/5/11  1974

Former reference: F.48

Contents:
Correspondence re Pseudomonas aeruginosa strains.

Knowles, C.J.  CLARKE/F/5/12  1976, 1984

Former reference: F.49

Contents:
Includes copy of typescript paper 'The effect of cyclic AMP on respiratory activity in Escherichia coli K-12', sent to Clarke for comment after its rejection for publication, 1976.

Kornberg, H.L.  CLARKE/F/5/13  1963

Former reference: F.50

Contents:
One letter only from Kornberg re propionate and growth in Pseudomonas aeruginosa.

Simon, B.  CLARKE/F/5/14  1992, 1994, 2002

Former reference: F.51

Administrative history:
Simon was Professor of Education at the University of Leicester.

Contents:
Personal news; history of Cirencester schools.

Slater, J.H.  CLARKE/F/5/15  1981-1991

Former reference: F.52

Administrative history:
Slater was Professor of Applied Microbiology at the University of Wales.

Contents:
Includes typescript of 'Environmentally directed mutations in the dehalogenase system of Pseuodmonas putida' by Slater et al, sent to Clarke for comment.

Smith, W.  CLARKE/F/5/16  1985

Former reference: F.53

Contents:
One letter only.

Spratt, B.G.  CLARKE/F/5/17  1991

Former reference: F.54

Weightman, A.J.  CLARKE/F/5/18  1991

Former reference: F.55

Conditions of access: Restrict: application for grant.

Contents:
Travel grant.

Wright, L.F.  CLARKE/F/5/19  1977

Former reference: F.56

Contents:
Correspondence and papers re work on Pseudomonas aeruginosa.

'Europe'  CLARKE/F/6  1978-1988

Former reference: F.57-F.59

2 items

Stalon, V.  CLARKE/F/6/1  1978-1985

Former reference: F.58, F.59

Administrative history:
Victor Stalon worked in the microbiology unit of the Science Faculty of the Université Libre de Bruxelles, Belgium.

1978-1979  CLARKE/F/6/1/a  [n.d.]

Former reference: F.57

Contents:
Correspondence re arginine metabolism.

1983-1985  CLARKE/F/6/1/b  [n.d.]

Former reference: F.58

Contents:
Includes draft typescript of 'L-arginine utilization by Pseudomonas species' by Stalon and A. Mercenier sent to Clarke for comment, 1983, and further correspondence on arginine pathways, 1984-1985.

Miscellaneous correspondents  CLARKE/F/6/2  [n.d.]

Former reference: F.59

'Correspondence with scientists US'  CLARKE/F/7  1968-1997

Former reference: F.60-F.73

14 items

Contents:
Correspondence with US scientists and other colleagues. Arranged in alphabetical order.

Dykhuizen, D.E.  CLARKE/F/7/1  1985

Former reference: F.60

Contents:
Letter, with enclosures, re mutation in Escherichia coli

Gunsalus, I.C.  CLARKE/F/7/2  1969-1981

Former reference: F.61

Contents:
Correspondence re Pseudomonas aeruginosa, personal news. Includes typescript biographical note on Gunsalus by Clarke.

Knowles, J.R.  CLARKE/F/7/3  1976, 1985

Former reference: F.62

Kustu, S.  CLARKE/F/7/4  1980

Former reference: F.63

Contents:
One letter only re work on nitrogen control.

Lin, E.C.C.  CLARKE/F/7/5  1984

Former reference: F.64

Contents:
One letter only, of good wishes on retirement.

Miller, S.L.  CLARKE/F/7/6  1985

Former reference: F.65

Contents:
One letter only, with enclosures.

Olsen, R.  CLARKE/F/7/7  1980

Former reference: F.66

Administrative history:
Clarke lectured to the Division of Biological Sciences course on Mechanisms of Molecular Evolution on 'Experimental evolution of biochemical pathways' on 4 November 1980.

Contents:
Correspondence re visit by Clarke to University of Michigan.

Ornston, L.N.  CLARKE/F/7/8  1972-1973, 1985

Former reference: F.67

Contents:
Chiefly correspondence re Ornston's contribution to Genetics and Biochemistry of Pseudomonas, eds. Clarke and M.H. Richmond (London: Wiley, 1975).

Palleroni, N.J.  CLARKE/F/7/9  1973

Former reference: F.68

Contents:
Correspondence re Palleroni's contribution to Genetics and Biochemistry of Pseudomonas, eds. Clarke and M.H. Richmond (London: Wiley, 1975).

Phibbs, P.V.  CLARKE/F/7/10  1991

Former reference: F.69

Contents:
Exchange re proposal to establish a Pseudomonas stock culture collection at East Carolina University.

Reiner, A.M.  CLARKE/F/7/11  1977

Former reference: F.70

Sager, R.D.  CLARKE/F/7/12  1980-1997

Former reference: F.71

Administrative history:
Ruth Sager was a distinguished cancer geneticist. She was one of the first women to be elected to the US National Academy of Sciences and the American Academy of Arts and Sciences.

Contents:
Chiefly correspondence re visits by Sager and A.B. Pardee to the UK and personal news.

Shooter, E.  CLARKE/F/7/13  1986-1997

Former reference: F.72

Contents:
Personal news.

Stanier, R.Y.  CLARKE/F/7/14  1968-1969

Former reference: F.73

Administrative history:
Clarke wrote the Royal Society Biographical Memoir of Stanier, see C.15-C.19.

Contents:
Correspondence re properties of strains of Pseudomonas. Also includes brief typescript note by Clarke on Stanier's influence on her work.

Miscellaneous correspondence found loose  CLARKE/F/8  1983-2000

Former reference: F.74-F.78

5 items

Contents:
In chronological order.

1983, 1985, 1988  CLARKE/F/8/1  [n.d.]

Former reference: F.74

1986  CLARKE/F/8/2  [n.d.]

Former reference: F.75

Conditions of access: Restrict: references

1994  CLARKE/F/8/3  [n.d.]

Former reference: F.76

Contents:
Exchange with J.R. Quayle re his Royal Society Biographical Memoir of the biochemist W.C. Evans (1911-1988).

1991  CLARKE/F/8/4  [n.d.]

Former reference: F.77

Conditions of access: Restrict

2000  CLARKE/F/8/5  [n.d.]

Former reference: F.78

Conditions of access: Restrict: job reference

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